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MSLSRRHALLGTGITLAASAVAGCATYGRSVTPAPAAPESPGPEETTETTAALAATADVPVGSGIVVGDV VLTQPNTGEFKAFSAVCTHAGCTVSEVIGASITCPCHGSSFHLDGTVATGPAKRALDTTPITVQGDSITR A
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3864 | - | - | 100% (141) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1755 | - | 1e-30 | 49.28% (138) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3559 | - | 1e-06 | 43.94% (66) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2218 | qcrA | 4e-08 | 46.97% (66) | Rieske iron-sulfur protein QcrA |
| M. gilvum PYR-GCK | Mflv_4709 | - | 6e-28 | 63.86% (83) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv2195 | qcrA | 4e-08 | 46.97% (66) | Rieske iron-sulfur protein QcrA |
| M. leprae Br4923 | MLBr_00880 | qcrA | 3e-08 | 46.15% (65) | putative Rieske iron-sulphur reductase component |
| M. abscessus ATCC 19977 | MAB_4653 | - | 2e-09 | 35.20% (125) | hypothetical protein MAB_4653 |
| M. marinum M | MMAR_3239 | qcrA | 9e-07 | 46.03% (63) | Rieske iron-sulfur protein QcrA |
| M. avium 104 | MAV_4414 | - | 2e-07 | 30.77% (130) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6548 | - | 2e-40 | 56.74% (141) | Rieske iron-sulfur protein |
| M. thermoresistible (build 8) | TH_1043 | qcrA | 6e-08 | 46.15% (65) | Probable Rieske iron-sulfur protein QcrA |
| M. ulcerans Agy99 | MUL_3552 | qcrA | 6e-07 | 46.03% (63) | Rieske iron-sulfur protein QcrA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3864|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3239|M.marinum_M -----------------------------------MSDGSTETGVSREPD
MUL_3552|M.ulcerans_Agy99 -----------------------------------MSDGSTETGVSREPD
Mb2218|M.bovis_AF2122/97 MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPD
Rv2195|M.tuberculosis_H37Rv MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPD
MLBr_00880|M.leprae_Br4923 ----------------------------------MSLNPKDGAGASRELD
TH_1043|M.thermoresistible__bu -----------------------------MTDDVKGTDTPGQLGVPGQPT
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
Mvan_3864|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3239|M.marinum_M EAALAEMSQQELLELGGSIDGVRIAHKEPRWPVEGTKAEKRAERGVALWL
MUL_3552|M.ulcerans_Agy99 EAALAEMSQQELLELGGSIDGVRIAHKEPRWPVEGTKAEKRAERGVALWL
Mb2218|M.bovis_AF2122/97 EAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWL
Rv2195|M.tuberculosis_H37Rv EAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWL
MLBr_00880|M.leprae_Br4923 ETTQGTMSREELVALGGRLDGVNTVYKEQRWPIEGTKAEKRTERMVTFWL
TH_1043|M.thermoresistible__bu EAELAQMSREELLELGGKLDGVQTVFKEPRWPVPGTKAEKRAERQVAFWL
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
Mvan_3864|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3239|M.marinum_M LLGGFFGLALLLVFLFWPWEYKPSGDKGNLLYSLATPLYGLTFGMSVLAI
MUL_3552|M.ulcerans_Agy99 LLGGFFGLALLLVFLFWPWEYKPSGDKGNLLYSLATPLYGLTFGMSVLAI
Mb2218|M.bovis_AF2122/97 LLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSI
Rv2195|M.tuberculosis_H37Rv LLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSI
MLBr_00880|M.leprae_Br4923 LLGGVLGLTLLLIFLFWPWEYKPKEASGSFLYTIATPLYGLTFGLSILAI
TH_1043|M.thermoresistible__bu MLGGFSGLALLLIFLFWPWEYRPLGDEGAWIYNLTTPLYGLTFGLSILSI
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
Mvan_3864|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3239|M.marinum_M AIGAVLFQKRFIPEEITIQDRHDGASREVDRKTVVANLADAFEASTIGRR
MUL_3552|M.ulcerans_Agy99 AIGAVLFQKRFIPEEITIQDRHDGASREVDRKTVVANLADAFEASTIGRR
Mb2218|M.bovis_AF2122/97 AIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRR
Rv2195|M.tuberculosis_H37Rv AIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRR
MLBr_00880|M.leprae_Br4923 AIGAVQFQKRFIPEEISIQERHDGASPEIDRKTVVANLTDALESSTIRRR
TH_1043|M.thermoresistible__bu GIGAVLYQKKFIPHEISIQERHDGRSPEIHRKTIVANLTDALEGSTIKRR
MAB_4653|M.abscessus_ATCC_1997 ---------------MNPRGLRRYVDDLLRGRRPKSFRPDDFEAAQIRTA
MAV_4414|M.avium_104 ---------------MNARGLRRYVDDLLRGRRPRPFLPDDFEAAQLRTA
Mvan_3864|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3239|M.marinum_M KMVGASLGVGLGAFGLGTLVAFAGGLIKNPWKPVVPTADGKKAVLWTSGW
MUL_3552|M.ulcerans_Agy99 KMVGASLGVGLGAFGLGTLVAFAGGLIKNPWKPVVPTADGKKAVLWTSGW
Mb2218|M.bovis_AF2122/97 KLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGW
Rv2195|M.tuberculosis_H37Rv KLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGW
MLBr_00880|M.leprae_Br4923 KLIGLSLGVGLGAFGLSTLVTFIGGFIKNPWKPVVPTANGMKAMLWTSGW
TH_1043|M.thermoresistible__bu KVIGLSLGLGLGAFGLGTLVAFVGGLVKNPWKPVVPTAEGKKAELWTSGW
MAB_4653|M.abscessus_ATCC_1997 IELRASR---------------PGD---DAPSQEFLAELGRRLAEQISDT
MAV_4414|M.avium_104 IELRAAR---------------PDSEVADAPRPEFLADLHRRLAEQMSGA
Mvan_3864|M.vanbaalenii_PYR-1 --------MSLSRRHALLGTG-------ITLAASAVAGC--ATYGRSVTP
MSMEG_6548|M.smegmatis_MC2_155 --------MHATRRQALVGTG-------ITLAATAVAGC--TTYGD--GP
Mflv_4709|M.gilvum_PYR-GCK --------MWRWRSPGRQCS-----------SARASASP--RSRWRHARE
MMAR_3239|M.marinum_M TPRFHGETIYLARATGLGDGPPYTKMRPEDLDAGGMETV--FPWRESDGD
MUL_3552|M.ulcerans_Agy99 TPRFHGETIYLARATGLGDGPPYAKMRPEDLDAGGMETV--FPWRESDGD
Mb2218|M.bovis_AF2122/97 TPRYQGETIYLARATGTEDGPPFIKMRPEDIDAGGMETV--FPWRESDGD
Rv2195|M.tuberculosis_H37Rv TPRYQGETIYLARATGTEDGPPFIKMRPEDMDAGGMETV--FPWRESDGD
MLBr_00880|M.leprae_Br4923 TPRYHGETIYLARATGSHSGAPFIRMRPEDVDAGGMETV--FPWRESDGD
TH_1043|M.thermoresistible__bu TPRYPGETIYLVRSTGAVGTAPFQKVRPEDIDAGGMETV--FPWRESDGD
MAB_4653|M.abscessus_ATCC_1997 PVSSAPRRWQAPRRTVLVGTSTAAAAAAVAVTADHLMTP---TPQTDTHQ
MAV_4414|M.avium_104 PTRPRPGR-GSTRRQVIVGTSAAATAAVAAVSIDRTVIAGQSGPDRAPQI
*
Mvan_3864|M.vanbaalenii_PYR-1 APAAP-ESPGPEETTETTAALAATADVPVGSGIVVGDVVLTQPNTGEFKA
MSMEG_6548|M.smegmatis_MC2_155 AKSDPSDSAGP--APGGGEVIAEVADVPVGSGVIVGDTVVTQPTAGVFKG
Mflv_4709|M.gilvum_PYR-GCK VRTRRDRRRGHLRRRARSWRRRPTSDVPVGSGTIVGEVVVTQPVAGEFKA
MMAR_3239|M.marinum_M GTTVESHEKLQRISMGVRNPVMLIRIKPTDMHRVVKRQGQESFNFGELFA
MUL_3552|M.ulcerans_Agy99 GTTVESHEKLQRISMGVRNPVMLIRIKPTDMHRVVKRQGQESFNFGELFA
Mb2218|M.bovis_AF2122/97 GTTVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFA
Rv2195|M.tuberculosis_H37Rv GTTVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFA
MLBr_00880|M.leprae_Br4923 GTTMESHEKLITIKMGIRNPVMLIRIRPSDMPRVVKRRGQENFNFGEFFA
TH_1043|M.thermoresistible__bu GTTPESAHKLTEIAMGVRNPVMLIRIRPQDMPRVVKRKGQESFNYGEFFA
MAB_4653|M.abscessus_ATCC_1997 APGEIVPNTGSWQRVAVSNAVPDGGVHPFDLGFVNG---FVRRVGGRVEA
MAV_4414|M.avium_104 ASGTLAPNQGSWQRVAASSEVPDGVLRAFDLGAVSG---FVRRVDGKVQA
. . : * . .
Mvan_3864|M.vanbaalenii_PYR-1 FSAVCTHAGCTVSEVIGA--SITCPCHGSSFHLDG--TVATGPAKRALDT
MSMEG_6548|M.smegmatis_MC2_155 FSSKCTHKGCTVNEIADG--TIHCPCHGSEFNLDG--TVAKGPATRPLDA
Mflv_4709|M.gilvum_PYR-GCK FSAVCTHTGCLVNKVADG--TIDCPCHGSRFSLDG--AVVNGPAEKPLQP
MMAR_3239|M.marinum_M FTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQ
MUL_3552|M.ulcerans_Agy99 FTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQ
Mb2218|M.bovis_AF2122/97 FTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQ
Rv2195|M.tuberculosis_H37Rv FTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQ
MLBr_00880|M.leprae_Br4923 FTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALQYAKPIFGPAARALAQ
TH_1043|M.thermoresistible__bu YTKVCSHLGCPASLYEQQTHLLLCPCHQSQFDLLHYARPVFGPAARALAQ
MAB_4653|M.abscessus_ATCC_1997 VSGVCTHQGCKL-WFDGTNNRLQCPCHTTSFTTDGRVITHQLPIAPKPLP
MAV_4414|M.avium_104 ISGVCTHQGCKL-WFDAPDDTLRCPCHTTSFSPSGKVLTHQLPIEPKPLP
: *:* ** : **** : * *
Mvan_3864|M.vanbaalenii_PYR-1 TPITVQGDSITRA------------------
MSMEG_6548|M.smegmatis_MC2_155 KSVEVEGDSIVLQ------------------
Mflv_4709|M.gilvum_PYR-GCK VAVRVQGDSIVAD------------------
MMAR_3239|M.marinum_M LPITIDTEGYLVANGDFIEPVGPAFWERTTS
MUL_3552|M.ulcerans_Agy99 LPITIDTEGYLVANGDFIEPVGPAFWERTTS
Mb2218|M.bovis_AF2122/97 LPITIDTDGYLVANGDFVEPVGPAFWERTTT
Rv2195|M.tuberculosis_H37Rv LPITIDTDGYLVANGDFVEPVGPAFWERTTT
MLBr_00880|M.leprae_Br4923 LPITIDTDGYLVANGDFVEPVGPAFWERTT-
TH_1043|M.thermoresistible__bu LPITVNEDGYLVANGDFIEPVGPAFWERKS-
MAB_4653|M.abscessus_ATCC_1997 TLQVRETEGHIEVFAPDRPV-----------
MAV_4414|M.avium_104 ALMVREADGIIEVFAPVRRT-----------
: :.