For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
WRWRSPGRQCSSARASASPRSRWRHAREVRTRRDRRRGHLRRRARSWRRRPTSDVPVGSGTIVGEVVVTQ PVAGEFKAFSAVCTHTGCLVNKVADGTIDCPCHGSRFSLDGAVVNGPAEKPLQPVAVRVQGDSIVAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4709 | - | - | 100% (138) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0732 | - | 4e-06 | 39.13% (69) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00880 | qcrA | 8e-05 | 34.92% (63) | putative Rieske iron-sulphur reductase component |
| M. abscessus ATCC 19977 | MAB_4653 | - | 2e-08 | 31.51% (146) | hypothetical protein MAB_4653 |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4414 | - | 5e-08 | 38.53% (109) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_6548 | - | 3e-30 | 67.47% (83) | Rieske iron-sulfur protein |
| M. thermoresistible (build 8) | TH_1303 | - | 2e-07 | 39.08% (87) | iron-sulfur binding oxidoreductase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1755 | - | 8e-34 | 73.81% (84) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu MTSLWLADRTNQPPPPRTLDAGDRRADVVVVGAGITGLITAVLLARGGKD
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu VLVVEAAYVGAGATGNTTAKISVLQGSRMSKILAKHGPRRARQYVEGNLE
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MLBr_00880|M.leprae_Br4923 --------------------------------------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu GLEWLVRHCAAHGLSVQREDAYTFAQSLQGVPAARTEYLAAKIAGLDVEW
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MLBr_00880|M.leprae_Br4923 -------------MSLNPKDGAGASRELDETTQGTMSREELVALGGRLDG
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu VDDAEGGVPFPFHGAVRLADQAQFDPMPLLDSLVVELEERGGRLVQGLRV
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MLBr_00880|M.leprae_Br4923 VNTVYKEQRWPIEGTKAEKRTERMVTFWLLLGGVLGLTLLLIFLFWPWEY
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu HKVSGRGDGLTLHARSGAGDEFDLRADRCVLATGIPILDRGGFFARLEPN
MAB_4653|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4414|M.avium_104 --------------------------------------------------
MLBr_00880|M.leprae_Br4923 KPKEASGSFLYTIATPLYGLTFGLSILAIAIG------------------
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu RSYCLAYEVPGEITRGMYISTDSPTRSLRYAPTGAGDLLIVGGAGHPVGH
MAB_4653|M.abscessus_ATCC_1997 -----------MNPRGLRRYVDDLLRGRRPKSFRPDD---FEAAQIRTAI
MAV_4414|M.avium_104 -----------MNARGLRRYVDDLLRGRRPRPFLPDD---FEAAQLRTAI
MLBr_00880|M.leprae_Br4923 --AVQFQKRFIPEEISIQERHDGASPEIDRKTVVANLTDALESSTIRRRK
MSMEG_6548|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_1755|M.vanbaalenii_PYR-1 -------------------------------------------------M
Mflv_4709|M.gilvum_PYR-GCK --------------------------------------------------
TH_1303|M.thermoresistible__bu EKNPASSVAELDEWARRHFPGAQQRYFWSAQDYSPIDDLPYVGPILPGNE
MAB_4653|M.abscessus_ATCC_1997 ELRASRPGD---DAPSQEFLAELGRRLAEQISDTPVSSAPRRW--QAPRR
MAV_4414|M.avium_104 ELRAARPDSEVADAPRPEFLADLHRRLAEQMSGAPTRPRPGR---GSTRR
MLBr_00880|M.leprae_Br4923 LIGLSLGVGLGAFGLSTLVTFIGGFIKNPWKPVVPTANGMKAMLWTSGWT
MSMEG_6548|M.smegmatis_MC2_155 -MHATRRQALVGTGITLAATAVAGCTTYGDGPAKSDPSDSAGPAPGGGEV
Mvan_1755|M.vanbaalenii_PYR-1 AVEIPRKTVLAGAGLGLAAAAVAACS---GGTSKR-------PA---GEE
Mflv_4709|M.gilvum_PYR-GCK -MWRWRSPGRQCSSARASASPRSRWRHAREVRTRRDRRRGHLRRRARSWR
TH_1303|M.thermoresistible__bu SIFVAIGFDKWGMTNGAAAALALSSRILGGRTDWAEAFASWSPHEVSGIP
MAB_4653|M.abscessus_ATCC_1997 TVLVGTSTAAAAAAVAVTADHLMTP---TPQTDTHQAPGEIVPNTGSWQR
MAV_4414|M.avium_104 QVIVGTSAAATAAVAAVSIDRTVIAGQSGPDRAPQIASGTLAPNQGSWQR
MLBr_00880|M.leprae_Br4923 PRYHGETIYLARATGSHSGAPFIRMRPEDVDAGGMETVFPWRESDGDGTT
:
MSMEG_6548|M.smegmatis_MC2_155 IAEVADVPV----------------------GSGVIVG---DTVVTQPTA
Mvan_1755|M.vanbaalenii_PYR-1 LTSTADVPV----------------------GSGVILG---DVLVTQPVA
Mflv_4709|M.gilvum_PYR-GCK RRPTSDVPV----------------------GSGTIVG---EVVVTQPVA
TH_1303|M.thermoresistible__bu KAMMLNLQVGMYLARGWLTPVTRTGDRSPDDGCGVVSGPPWHLQARSRVD
MAB_4653|M.abscessus_ATCC_1997 VAVSNAVPDGG----------------VHPFDLGFVNG------FVRRVG
MAV_4414|M.avium_104 VAASSEVPDGV----------------LRAFDLGAVSG------FVRRVD
MLBr_00880|M.leprae_Br4923 MESHEKLITIKMG--------IRNPVMLIRIRPSDMPRVVKRRGQENFNF
: . :
MSMEG_6548|M.smegmatis_MC2_155 GVFKGFSSKCTHKGCTVN--EIADGTIHCPCHGSEFNLDGTVAKG---PA
Mvan_1755|M.vanbaalenii_PYR-1 GEYKGLPAVCTHNGCLVN--EIADETIYCPCHGSMFSLDGEVVAG---PA
Mflv_4709|M.gilvum_PYR-GCK GEFKAFSAVCTHTGCLVN--KVADGTIDCPCHGSRFSLDGAVVNG---PA
TH_1303|M.thermoresistible__bu GVEHRVSPVCPHLGGIVNW-NDADQAWECPLHGSRFAPDGALLEG---PA
MAB_4653|M.abscessus_ATCC_1997 GRVEAVSGVCTHQGCKLWF-DGTNNRLQCPCHTTSFTTDGRVITHQLPIA
MAV_4414|M.avium_104 GKVQAISGVCTHQGCKLWF-DAPDDTLRCPCHTTSFSPSGKVLTHQLPIE
MLBr_00880|M.leprae_Br4923 GEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALQYAKPIFG-PA
* .. *.* * . . ** * : *
MSMEG_6548|M.smegmatis_MC2_155 TRPLDAKSVEVEGDSIVLQ-----------------
Mvan_1755|M.vanbaalenii_PYR-1 ERPLEPVAIHVQGESIVLGT----------------
Mflv_4709|M.gilvum_PYR-GCK EKPLQPVAVRVQGDSIVAD-----------------
TH_1303|M.thermoresistible__bu TRGLTAS-----------------------------
MAB_4653|M.abscessus_ATCC_1997 PKPLPTLQVRETEGHIEVFAPDRPV-----------
MAV_4414|M.avium_104 PKPLPALMVREADGIIEVFAPVRRT-----------
MLBr_00880|M.leprae_Br4923 ARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTT
: *