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VYTEQDLRQLAERGAAELGEHATAEELLRWTDEHFGGDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGY HFVETIGTRDAVEAVYDVNVVNVRPEHSVAEQDALLGKNLFERNANECCRLRKVEPLSKALRGYSAWVTG IRRVEAPTRANAPLISWDSAFGLVKINPLAAWSDDDMQDYIDANGILVNPLVDEGYPSIGCAPCTNKPVE GADPRSGRWAGLSKTECGLHAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3858 | - | - | 100% (232) | phosphoadenosine phosphosulfate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2413 | cysH | 1e-100 | 72.06% (247) | phosphoadenosine phosphosulfate reductase |
| M. gilvum PYR-GCK | Mflv_2685 | - | 1e-124 | 91.06% (235) | phosphoadenosine phosphosulfate reductase |
| M. tuberculosis H37Rv | Rv2392 | cysH | 1e-100 | 72.06% (247) | phosphoadenosine phosphosulfate reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1661c | - | 1e-103 | 78.76% (226) | phosphoadenosine phosphosulfate reductase (CysH) |
| M. marinum M | MMAR_3417 | cysH_1 | 1e-101 | 71.97% (239) | 3'-phosphoadenosine 5'-phosphosulfate reductase CysH_1 |
| M. avium 104 | MAV_2153 | - | 9e-98 | 69.71% (241) | phosphoadenosine phosphosulfate reductase |
| M. smegmatis MC2 155 | MSMEG_4528 | - | 1e-114 | 84.78% (230) | phosphoadenosine phosphosulfate reductase |
| M. thermoresistible (build 8) | TH_1444 | cysH | 1e-108 | 79.17% (240) | PROBABLE 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE REDUCTASE |
| M. ulcerans Agy99 | MUL_2696 | cysH_1 | 1e-101 | 72.38% (239) | phosphoadenosine phosphosulfate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3858|M.vanbaalenii_PYR-1 ----MYT--EQDLRQLAERGAAELGEHATAEELLRWTDEHFG--------
Mflv_2685|M.gilvum_PYR-GCK MT-DTMS--ETDLQELAERGAAELGEHATAQDLLRWTDENFGPASG----
TH_1444|M.thermoresistible__bu MT-DLMT--ETDLRALAERGAAEMAG-AGAEELLRWTDEHFGGAPAG---
MSMEG_4528|M.smegmatis_MC2_155 MT-DVTTSTENELRELAERGAAELAD-ASAEELLRWTDEHFG--------
MAB_1661c|M.abscessus_ATCC_199 MSRETTTKDLDSLRALAERGAAELQD-ASAEELLRWTDENFG--------
Mb2413|M.bovis_AF2122/97 MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
Rv2392|M.tuberculosis_H37Rv MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
MMAR_3417|M.marinum_M MSD---QPNETQLRELAARGAAEMEG-ASATDLLRWADEHFGGINGP---
MUL_2696|M.ulcerans_Agy99 MSD---QPNETQLRELAARGAAEMEG-ASATDLLRWADEHFGGINGP---
MAV_2153|M.avium_104 MSDGATDFTEEQLRELAERGASELEG-ASAIDILRWTDEHFGPVDGP---
.*: ** ***:*: * * ::***:** **
Mvan_3858|M.vanbaalenii_PYR-1 ---------GDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
Mflv_2685|M.gilvum_PYR-GCK --------RGDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
TH_1444|M.thermoresistible__bu ----SAGARSGYVVASNMQDAVLIHLAAKVRPGVDVLFLDTGYHFAETIG
MSMEG_4528|M.smegmatis_MC2_155 ---------GNYVVASNMQDAVLVEMAAKVRPGVDVLFLDTGYHFAETIG
MAB_1661c|M.abscessus_ATCC_199 ---------GNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAETIG
Mb2413|M.bovis_AF2122/97 VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
Rv2392|M.tuberculosis_H37Rv VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
MMAR_3417|M.marinum_M ----RGWATCNYVVASNMQDAVLIDLASKVRPGVPVIFLDTGYHFAETIG
MUL_2696|M.ulcerans_Agy99 ----RGWATCNYVVASNMQDAVLIDLASKVRPGVPVIFLDTGYHFAETIG
MAV_2153|M.avium_104 ----RGWATCKYVVACNMQDAVTVSLASDVRPGVPVLFLDTGYHFPETIG
*:**.** *** : :*:.***** *:******** ****
Mvan_3858|M.vanbaalenii_PYR-1 TRDAVEAVYDVNVVNVRPEHSVAEQDALLGKNLFERNANECCRLRKVEPL
Mflv_2685|M.gilvum_PYR-GCK TRDAVEAVYDVNVVNVRPEHSVTEQDAMLGRNLFERNANECCRLRKVVPL
TH_1444|M.thermoresistible__bu TRDAVQAVYDVNVVNVTAEHTVAEQDRLLGKDLFARDPNECCRLRKVEPL
MSMEG_4528|M.smegmatis_MC2_155 TRDAVEAVYDVHVVNVTPERTVAEQDELLGKNLFARDPGECCRLRKVVPL
MAB_1661c|M.abscessus_ATCC_199 TRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPL
Mb2413|M.bovis_AF2122/97 TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
Rv2392|M.tuberculosis_H37Rv TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
MMAR_3417|M.marinum_M TRDAIEAVYDIRVLNISPEHTVAEQDKLLGKDLFARDPNECCRLRKVVPL
MUL_2696|M.ulcerans_Agy99 TRDAIEAVYDIRVLNISPEHTVAEQDKLLGKDLFARDPNECCRLRKVVPL
MAV_2153|M.avium_104 TRDAVEAVYDIHLLNVTPEHTVAEQDELLGKDLFARDPNECCRLRKVEPL
****:::***:.::*: .*::*::** ::*::** :. ******** **
Mvan_3858|M.vanbaalenii_PYR-1 SKALRGYSAWVTGIRRVEAPTRANAPLISWDSAFGLVKINPLAAWSDDDM
Mflv_2685|M.gilvum_PYR-GCK SKALSGYSAWVTGIRRVEAPTRANAPLISWDKAFGLVKINPLAAWSDDDM
TH_1444|M.thermoresistible__bu SRALRGYSAWVTGIRRVEAPTRANAPFISFDESFGLVKINPLAAWTDQDM
MSMEG_4528|M.smegmatis_MC2_155 TNALKGYSAWVTGIRRVEAPTRANAPLISWDNAFGLVKINPIAAWTDEDM
MAB_1661c|M.abscessus_ATCC_199 RKSLAGYAAWVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDEDM
Mb2413|M.bovis_AF2122/97 GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
Rv2392|M.tuberculosis_H37Rv GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
MMAR_3417|M.marinum_M TNALRGYAAWITGLRRVESPTRANAPVISFDEAFKLVKINPLVSWTDQDV
MUL_2696|M.ulcerans_Agy99 TNALRGYAAWITGLRRVESPTRANAPVISFDEAFKLVKINPLVAWTDQDV
MAV_2153|M.avium_104 RRALRGYAAWVSGLRRVEAPTRADAPLISFDESFKVVKVNPIAAWTDEQV
.:* **:**::*:***::****:**.:*:*.:* :**:*.:.:*:*:::
Mvan_3858|M.vanbaalenii_PYR-1 QDYIDANGILVNPLVDEGYPSIGCAPCTNKPVEGADPRSGRWAGLSKTEC
Mflv_2685|M.gilvum_PYR-GCK QDYIDANGILVNPLVDEGYPSIGCAPCTHKPVEGADPRSGRWLGQSKTEC
TH_1444|M.thermoresistible__bu QDYIQTHGVLVNPLVDEGYPSIGCAPCTTKPAPGADPRSGRWQGTGKIEC
MSMEG_4528|M.smegmatis_MC2_155 QNYIDANGILVNPLVYEGYPSIGCAPCTSKPIPGADPRSGRWAGLSKTEC
MAB_1661c|M.abscessus_ATCC_199 QKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTEC
Mb2413|M.bovis_AF2122/97 QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
Rv2392|M.tuberculosis_H37Rv QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
MMAR_3417|M.marinum_M QDYIQSNNVLVNPLVDEGYPSIGCAPCTAKPAVGEDPRSGRWRGRTKTEC
MUL_2696|M.ulcerans_Agy99 QDYIQSNNVLVNPLVDEGYPSIGCAPCTAKPAVGEDPRSGRWRGRTKTEC
MAV_2153|M.avium_104 DEYIERNGVLVNPLVQEGYPSIGCAPCTAKPAPGEDPRSGRWRGRNKVEC
:.** :. ****** ************ ** * *.***** * * **
Mvan_3858|M.vanbaalenii_PYR-1 GLHAS
Mflv_2685|M.gilvum_PYR-GCK GLHAS
TH_1444|M.thermoresistible__bu GLHSS
MSMEG_4528|M.smegmatis_MC2_155 GLHVS
MAB_1661c|M.abscessus_ATCC_199 GLHAS
Mb2413|M.bovis_AF2122/97 GLHAS
Rv2392|M.tuberculosis_H37Rv GLHAS
MMAR_3417|M.marinum_M GLHAS
MUL_2696|M.ulcerans_Agy99 GLHAS
MAV_2153|M.avium_104 GLHAS
*** *