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M. abscessus ATCC 19977 MAB_1661c (-)

annotation: phosphoadenosine phosphosulfate reductase (CysH)
coordinates: 1688935 - 1689648
length: 237

SRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAAQVRPGVDVLFL
DTGYHFAETIGTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPLRKSLAGYAA
WVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDEDMQKYIDEHGTLVNPLVDEGYPSIGCAPCTA
KPVLGGDARSGRWQGLAKTECGLHAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1661c--100% (237)phosphoadenosine phosphosulfate reductase (CysH)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2413cysH1e-10271.26% (254) phosphoadenosine phosphosulfate reductase
M. gilvum PYR-GCKMflv_2685-1e-10073.22% (239) phosphoadenosine phosphosulfate reductase
M. tuberculosis H37RvRv2392cysH1e-10271.26% (254) phosphoadenosine phosphosulfate reductase
M. leprae Br4923-----
M. marinum MMMAR_3711cysH1e-10172.06% (247) 3'-phosphoadenosine 5'-phosphosulfate reductase CysH
M. avium 104MAV_1786-1e-10171.66% (247) phosphoadenosine phosphosulfate reductase
M. smegmatis MC2 155MSMEG_4528-1e-11181.20% (234) phosphoadenosine phosphosulfate reductase
M. thermoresistible (build 8)TH_1444cysH1e-10375.74% (235) PROBABLE 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE REDUCTASE
M. ulcerans Agy99MUL_2696cysH_11e-10173.19% (235) phosphoadenosine phosphosulfate reductase
M. vanbaalenii PYR-1Mvan_3858-1e-10378.76% (226) phosphoadenosine phosphosulfate reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2685|M.gilvum_PYR-GCK          MT-DTMS--ETDLQELAERGAAELGEHATAQDLLRWTDENFGP-------
Mvan_3858|M.vanbaalenii_PYR-1       ----MYT--EQDLRQLAERGAAELGEHATAEELLRWTDEHFG--------
TH_1444|M.thermoresistible__bu      MT-DLMT--ETDLRALAERGAAEMAG-AGAEELLRWTDEHFGG-------
MSMEG_4528|M.smegmatis_MC2_155      MT-DVTTSTENELRELAERGAAELAD-ASAEELLRWTDEHFG--------
MAB_1661c|M.abscessus_ATCC_199      MSRETTTKDLDSLRALAERGAAELQD-ASAEELLRWTDENFG--------
Mb2413|M.bovis_AF2122/97            MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
Rv2392|M.tuberculosis_H37Rv         MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
MAV_1786|M.avium_104                MTERTTKLPEAELRELAARGAAELEG-ASASDVLRWTDETFG-------G
MUL_2696|M.ulcerans_Agy99           MSDQPN---ETQLRELAARGAAEMEG-ASATDLLRWADEHFG-------G
MMAR_3711|M.marinum_M               MIETSN-LTEAELRELAARGAAELEG-ASATELLQWTDETFG----GANR
                                               .*: ** *****:   * * ::*:*:** **        

Mflv_2685|M.gilvum_PYR-GCK          ASG-----RGDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
Mvan_3858|M.vanbaalenii_PYR-1       ---------GDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
TH_1444|M.thermoresistible__bu      APAGSAGARSGYVVASNMQDAVLIHLAAKVRPGVDVLFLDTGYHFAETIG
MSMEG_4528|M.smegmatis_MC2_155      ---------GNYVVASNMQDAVLVEMAAKVRPGVDVLFLDTGYHFAETIG
MAB_1661c|M.abscessus_ATCC_199      ---------GNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAETIG
Mb2413|M.bovis_AF2122/97            VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
Rv2392|M.tuberculosis_H37Rv         VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
MAV_1786|M.avium_104                VNGPRGWATCNYVVASSMQEAVLIDLAAKVRPGVPVVFLDTGYHFAETIG
MUL_2696|M.ulcerans_Agy99           INGPRGWATCNYVVASNMQDAVLIDLASKVRPGVPVIFLDTGYHFAETIG
MMAR_3711|M.marinum_M               AAGVAGVQTANYVVASNMQDAVLIDLASKVRPGVPVLFLDTGYHFAETIG
                                              .*:***.* :***:.:*::***** *:********.****

Mflv_2685|M.gilvum_PYR-GCK          TRDAVEAVYDVNVVNVRPEHSVTEQDAMLGRNLFERNANECCRLRKVVPL
Mvan_3858|M.vanbaalenii_PYR-1       TRDAVEAVYDVNVVNVRPEHSVAEQDALLGKNLFERNANECCRLRKVEPL
TH_1444|M.thermoresistible__bu      TRDAVQAVYDVNVVNVTAEHTVAEQDRLLGKDLFARDPNECCRLRKVEPL
MSMEG_4528|M.smegmatis_MC2_155      TRDAVEAVYDVHVVNVTPERTVAEQDELLGKNLFARDPGECCRLRKVVPL
MAB_1661c|M.abscessus_ATCC_199      TRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPL
Mb2413|M.bovis_AF2122/97            TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
Rv2392|M.tuberculosis_H37Rv         TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
MAV_1786|M.avium_104                TRDAIESVYDIRVLNVTPEHSVAEQDKLLGKDLFARDPGECCRLRKVAPL
MUL_2696|M.ulcerans_Agy99           TRDAIEAVYDIRVLNISPEHTVAEQDKLLGKDLFARDPNECCRLRKVVPL
MMAR_3711|M.marinum_M               SRDAVESVYDVQVLTITPEHTVAEQDKLLGKDLFARDPGECCRLRKVVPL
                                    :***:::***:.*:.: .*::*::** ::*::**  :. ******** **

Mflv_2685|M.gilvum_PYR-GCK          SKALSGYSAWVTGIRRVEAPTRANAPLISWDKAFGLVKINPLAAWSDDDM
Mvan_3858|M.vanbaalenii_PYR-1       SKALRGYSAWVTGIRRVEAPTRANAPLISWDSAFGLVKINPLAAWSDDDM
TH_1444|M.thermoresistible__bu      SRALRGYSAWVTGIRRVEAPTRANAPFISFDESFGLVKINPLAAWTDQDM
MSMEG_4528|M.smegmatis_MC2_155      TNALKGYSAWVTGIRRVEAPTRANAPLISWDNAFGLVKINPIAAWTDEDM
MAB_1661c|M.abscessus_ATCC_199      RKSLAGYAAWVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDEDM
Mb2413|M.bovis_AF2122/97            GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
Rv2392|M.tuberculosis_H37Rv         GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
MAV_1786|M.avium_104                GKTLRGYSAWVTGLRRSEAATRANAPVIGFDEGFKLVKVNPMATWTDEDV
MUL_2696|M.ulcerans_Agy99           TNALRGYAAWITGLRRVESPTRANAPVISFDEAFKLVKINPLVAWTDQDV
MMAR_3711|M.marinum_M               RQALSNFSAWVTGLRRVEAPTRANAPVISFDEAFKLVKINPLAAWSDDEV
                                     .:* .::**:**:** ::.******.:.:*. * ***:*.:.:*:*:::

Mflv_2685|M.gilvum_PYR-GCK          QDYIDANGILVNPLVDEGYPSIGCAPCTHKPVEGADPRSGRWLGQSKTEC
Mvan_3858|M.vanbaalenii_PYR-1       QDYIDANGILVNPLVDEGYPSIGCAPCTNKPVEGADPRSGRWAGLSKTEC
TH_1444|M.thermoresistible__bu      QDYIQTHGVLVNPLVDEGYPSIGCAPCTTKPAPGADPRSGRWQGTGKIEC
MSMEG_4528|M.smegmatis_MC2_155      QNYIDANGILVNPLVYEGYPSIGCAPCTSKPIPGADPRSGRWAGLSKTEC
MAB_1661c|M.abscessus_ATCC_199      QKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTEC
Mb2413|M.bovis_AF2122/97            QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
Rv2392|M.tuberculosis_H37Rv         QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
MAV_1786|M.avium_104                QNYIDEHNVLVNPLIYEGYSSIGCAPCTAKPLAGADPRSGRWQGLAKTEC
MUL_2696|M.ulcerans_Agy99           QDYIQSNNVLVNPLVDEGYPSIGCAPCTAKPAVGEDPRSGRWRGRTKTEC
MMAR_3711|M.marinum_M               QDYIVANNVLVNPLVDEGYPSIGCAPCTVKPAAGADPRSGRWQGLAKTEC
                                    *.**  :. *****: ***.******** **  * *.***** *  * **

Mflv_2685|M.gilvum_PYR-GCK          GLHAS
Mvan_3858|M.vanbaalenii_PYR-1       GLHAS
TH_1444|M.thermoresistible__bu      GLHSS
MSMEG_4528|M.smegmatis_MC2_155      GLHVS
MAB_1661c|M.abscessus_ATCC_199      GLHAS
Mb2413|M.bovis_AF2122/97            GLHAS
Rv2392|M.tuberculosis_H37Rv         GLHAS
MAV_1786|M.avium_104                GLHAS
MUL_2696|M.ulcerans_Agy99           GLHAS
MMAR_3711|M.marinum_M               GLHAS
                                    *** *