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SDGATDFTEEQLRELAERGASELEGASAIDILRWTDEHFGPVDGPRGWATCKYVVACNMQDAVTVSLASD VRPGVPVLFLDTGYHFPETIGTRDAVEAVYDIHLLNVTPEHTVAEQDELLGKDLFARDPNECCRLRKVEP LRRALRGYAAWVSGLRRVEAPTRADAPLISFDESFKVVKVNPIAAWTDEQVDEYIERNGVLVNPLVQEGY PSIGCAPCTAKPAPGEDPRSGRWRGRNKVECGLHAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2153 | - | - | 100% (247) | phosphoadenosine phosphosulfate reductase |
| M. avium 104 | MAV_1786 | - | e-108 | 73.28% (247) | phosphoadenosine phosphosulfate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2413 | cysH | 1e-110 | 74.41% (254) | phosphoadenosine phosphosulfate reductase |
| M. gilvum PYR-GCK | Mflv_2685 | - | 4e-96 | 69.17% (240) | phosphoadenosine phosphosulfate reductase |
| M. tuberculosis H37Rv | Rv2392 | cysH | 1e-110 | 74.41% (254) | phosphoadenosine phosphosulfate reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1661c | - | 2e-97 | 70.04% (247) | phosphoadenosine phosphosulfate reductase (CysH) |
| M. marinum M | MMAR_3417 | cysH_1 | 1e-116 | 79.41% (238) | 3'-phosphoadenosine 5'-phosphosulfate reductase CysH_1 |
| M. smegmatis MC2 155 | MSMEG_4528 | - | 1e-102 | 72.73% (242) | phosphoadenosine phosphosulfate reductase |
| M. thermoresistible (build 8) | TH_1444 | cysH | 1e-106 | 74.06% (239) | PROBABLE 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE REDUCTASE |
| M. ulcerans Agy99 | MUL_2696 | cysH_1 | 1e-117 | 79.83% (238) | phosphoadenosine phosphosulfate reductase |
| M. vanbaalenii PYR-1 | Mvan_3858 | - | 1e-97 | 69.71% (241) | phosphoadenosine phosphosulfate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2685|M.gilvum_PYR-GCK MT-DTMS--ETDLQELAERGAAELGEHATAQDLLRWTDENFGPASG----
Mvan_3858|M.vanbaalenii_PYR-1 ----MYT--EQDLRQLAERGAAELGEHATAEELLRWTDEHFG--------
TH_1444|M.thermoresistible__bu MT-DLMT--ETDLRALAERGAAEMAG-AGAEELLRWTDEHFGGAPAG---
MSMEG_4528|M.smegmatis_MC2_155 MT-DVTTSTENELRELAERGAAELAD-ASAEELLRWTDEHFG--------
MAB_1661c|M.abscessus_ATCC_199 MSRETTTKDLDSLRALAERGAAELQD-ASAEELLRWTDENFG--------
MMAR_3417|M.marinum_M MSD---QPNETQLRELAARGAAEMEG-ASATDLLRWADEHFGGINGP---
MUL_2696|M.ulcerans_Agy99 MSD---QPNETQLRELAARGAAEMEG-ASATDLLRWADEHFGGINGP---
MAV_2153|M.avium_104 MSDGATDFTEEQLRELAERGASELEG-ASAIDILRWTDEHFGPVDGP---
Mb2413|M.bovis_AF2122/97 MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
Rv2392|M.tuberculosis_H37Rv MSGETTRLTEPQLRELAARGAAELDG-ATATDMLRWTDETFGDIGGAGGG
.*: ** ***:*: * * ::***:** **
Mflv_2685|M.gilvum_PYR-GCK --------RGDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
Mvan_3858|M.vanbaalenii_PYR-1 ---------GDYIVASNMQDAVLVDLAAKVRPGVDVLFLDTGYHFVETIG
TH_1444|M.thermoresistible__bu ----SAGARSGYVVASNMQDAVLIHLAAKVRPGVDVLFLDTGYHFAETIG
MSMEG_4528|M.smegmatis_MC2_155 ---------GNYVVASNMQDAVLVEMAAKVRPGVDVLFLDTGYHFAETIG
MAB_1661c|M.abscessus_ATCC_199 ---------GNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAETIG
MMAR_3417|M.marinum_M ----RGWATCNYVVASNMQDAVLIDLASKVRPGVPVIFLDTGYHFAETIG
MUL_2696|M.ulcerans_Agy99 ----RGWATCNYVVASNMQDAVLIDLASKVRPGVPVIFLDTGYHFAETIG
MAV_2153|M.avium_104 ----RGWATCKYVVACNMQDAVTVSLASDVRPGVPVLFLDTGYHFPETIG
Mb2413|M.bovis_AF2122/97 VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
Rv2392|M.tuberculosis_H37Rv VSGHRGWTTCNYVVASNMADAVLVDLAAKVRPGVPVIFLDTGYHFVETIG
*:**.** *** : :*:.***** *:******** ****
Mflv_2685|M.gilvum_PYR-GCK TRDAVEAVYDVNVVNVRPEHSVTEQDAMLGRNLFERNANECCRLRKVVPL
Mvan_3858|M.vanbaalenii_PYR-1 TRDAVEAVYDVNVVNVRPEHSVAEQDALLGKNLFERNANECCRLRKVEPL
TH_1444|M.thermoresistible__bu TRDAVQAVYDVNVVNVTAEHTVAEQDRLLGKDLFARDPNECCRLRKVEPL
MSMEG_4528|M.smegmatis_MC2_155 TRDAVEAVYDVHVVNVTPERTVAEQDELLGKNLFARDPGECCRLRKVVPL
MAB_1661c|M.abscessus_ATCC_199 TRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPL
MMAR_3417|M.marinum_M TRDAIEAVYDIRVLNISPEHTVAEQDKLLGKDLFARDPNECCRLRKVVPL
MUL_2696|M.ulcerans_Agy99 TRDAIEAVYDIRVLNISPEHTVAEQDKLLGKDLFARDPNECCRLRKVVPL
MAV_2153|M.avium_104 TRDAVEAVYDIHLLNVTPEHTVAEQDELLGKDLFARDPNECCRLRKVEPL
Mb2413|M.bovis_AF2122/97 TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
Rv2392|M.tuberculosis_H37Rv TRDAIESVYDVRVLNVTPEHTVAEQDELLGKDLFARNPHECCRLRKVVPL
****:::***:.::*: .*::*::** ::*::** :. ******** **
Mflv_2685|M.gilvum_PYR-GCK SKALSGYSAWVTGIRRVEAPTRANAPLISWDKAFGLVKINPLAAWSDDDM
Mvan_3858|M.vanbaalenii_PYR-1 SKALRGYSAWVTGIRRVEAPTRANAPLISWDSAFGLVKINPLAAWSDDDM
TH_1444|M.thermoresistible__bu SRALRGYSAWVTGIRRVEAPTRANAPFISFDESFGLVKINPLAAWTDQDM
MSMEG_4528|M.smegmatis_MC2_155 TNALKGYSAWVTGIRRVEAPTRANAPLISWDNAFGLVKINPIAAWTDEDM
MAB_1661c|M.abscessus_ATCC_199 RKSLAGYAAWVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDEDM
MMAR_3417|M.marinum_M TNALRGYAAWITGLRRVESPTRANAPVISFDEAFKLVKINPLVSWTDQDV
MUL_2696|M.ulcerans_Agy99 TNALRGYAAWITGLRRVESPTRANAPVISFDEAFKLVKINPLVAWTDQDV
MAV_2153|M.avium_104 RRALRGYAAWVSGLRRVEAPTRADAPLISFDESFKVVKVNPIAAWTDEQV
Mb2413|M.bovis_AF2122/97 GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
Rv2392|M.tuberculosis_H37Rv GKTLRGYSAWVTGLRRVDAPTRANAPLVSFDETFKLVKVNPLAAWTDQDV
.:* **:**::*:***::****:**.:*:*.:* :**:*.:.:*:*:::
Mflv_2685|M.gilvum_PYR-GCK QDYIDANGILVNPLVDEGYPSIGCAPCTHKPVEGADPRSGRWLGQSKTEC
Mvan_3858|M.vanbaalenii_PYR-1 QDYIDANGILVNPLVDEGYPSIGCAPCTNKPVEGADPRSGRWAGLSKTEC
TH_1444|M.thermoresistible__bu QDYIQTHGVLVNPLVDEGYPSIGCAPCTTKPAPGADPRSGRWQGTGKIEC
MSMEG_4528|M.smegmatis_MC2_155 QNYIDANGILVNPLVYEGYPSIGCAPCTSKPIPGADPRSGRWAGLSKTEC
MAB_1661c|M.abscessus_ATCC_199 QKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTEC
MMAR_3417|M.marinum_M QDYIQSNNVLVNPLVDEGYPSIGCAPCTAKPAVGEDPRSGRWRGRTKTEC
MUL_2696|M.ulcerans_Agy99 QDYIQSNNVLVNPLVDEGYPSIGCAPCTAKPAVGEDPRSGRWRGRTKTEC
MAV_2153|M.avium_104 DEYIERNGVLVNPLVQEGYPSIGCAPCTAKPAPGEDPRSGRWRGRNKVEC
Mb2413|M.bovis_AF2122/97 QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
Rv2392|M.tuberculosis_H37Rv QEYIADNDVLVNPLVREGYPSIGCAPCTAKPAEGADPRSGRWQGLAKTEC
:.** :. ****** ************ ** * *.***** * * **
Mflv_2685|M.gilvum_PYR-GCK GLHAS
Mvan_3858|M.vanbaalenii_PYR-1 GLHAS
TH_1444|M.thermoresistible__bu GLHSS
MSMEG_4528|M.smegmatis_MC2_155 GLHVS
MAB_1661c|M.abscessus_ATCC_199 GLHAS
MMAR_3417|M.marinum_M GLHAS
MUL_2696|M.ulcerans_Agy99 GLHAS
MAV_2153|M.avium_104 GLHAS
Mb2413|M.bovis_AF2122/97 GLHAS
Rv2392|M.tuberculosis_H37Rv GLHAS
*** *