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MNLSGVGLWSSQLRYGNPDEAADAAAELDGLGFTALWIPDVGGPVLDSVDNLLSATEKTVIATGILNLWM HEPAEVAARYAALTETHGERFLLGIGVSHAPLIDSNEPGRYRKPLAATKAFLDGIDASPQPVPTANRVLA ALGPKMLQLSATRAGGAHPYLTTPEHTRQAREVLGSGPLLLPEQSVLLTDDRDQAREVGIDWLRSYLALP NYANNLLRLGFSEDDVSSVSDRLFDALIAWGDEDAVRRRVQEHLDAGADHVCVQVLTADPREFPREQWRR LAEALL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3854 | - | - | 100% (286) | hypothetical protein Mvan_3854 |
| M. vanbaalenii PYR-1 | Mvan_1368 | - | 8e-59 | 50.60% (251) | hypothetical protein Mvan_1368 |
| M. vanbaalenii PYR-1 | Mvan_1367 | - | 1e-55 | 45.28% (265) | hypothetical protein Mvan_1367 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 8e-56 | 47.97% (246) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_2688 | - | 1e-149 | 89.16% (286) | hypothetical protein Mflv_2688 |
| M. tuberculosis H37Rv | Rv3463 | - | 8e-56 | 47.97% (246) | hypothetical protein Rv3463 |
| M. leprae Br4923 | MLBr_00348 | - | 6e-08 | 20.96% (334) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3778 | - | 2e-55 | 44.53% (265) | hypothetical protein MAB_3778 |
| M. marinum M | MMAR_1083 | - | 2e-58 | 44.72% (284) | hypothetical protein MMAR_1083 |
| M. avium 104 | MAV_0983 | - | 1e-127 | 75.70% (284) | hypothetical protein MAV_0983 |
| M. smegmatis MC2 155 | MSMEG_1514 | - | 2e-56 | 47.41% (251) | hypothetical protein MSMEG_1514 |
| M. thermoresistible (build 8) | TH_2753 | - | 1e-126 | 75.79% (285) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0841 | - | 1e-52 | 44.15% (265) | hypothetical protein MUL_0841 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3854|M.vanbaalenii_PYR-1 MN----------LSGVGLWS------SQLRYGNPD----EAADAAAELDG
Mflv_2688|M.gilvum_PYR-GCK MN----------LSGVGLWS------SQLRYGNPE----EAAEAAAELDG
MAV_0983|M.avium_104 ME----------LTGVGIWS------SQLRYGDPA----ESADAAAELDE
TH_2753|M.thermoresistible__bu VN----------LEGVGIWS------SQLRYGDQA----EAAEAAAELEE
MMAR_1083|M.marinum_M MT-----------NAVSLKP------ELGRFGVWLGSRSITPELAGQIES
MUL_0841|M.ulcerans_Agy99 MT-----------NAVSLKP------ELGRFGVWLGSRSITPELAGQIES
Mb3492|M.bovis_AF2122/97 MT-----------NCAAGKPSSGP--NLGRFGSFG--RGVTPQQATEIEA
Rv3463|M.tuberculosis_H37Rv MT-----------NCAAGKPSSGP--NLGRFGSFG--RGVTPQQATEIEA
MSMEG_1514|M.smegmatis_MC2_155 MTGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFG--RGVTPAQAKEIEA
MAB_3778|M.abscessus_ATCC_1997 MG----------------ES------KLNRYGVWKG-GPVTPEQARTIED
MLBr_00348|M.leprae_Br4923 --------------MVERANAMKLGLQLGYWAAQPP--GNAAELVAAAEG
. :. :. . :
Mvan_3854|M.vanbaalenii_PYR-1 LGFTALWIPDVG-GPVLDSVDNLLSATEKTVIATGILNLWMHEPAEVAAR
Mflv_2688|M.gilvum_PYR-GCK LGFTALWIPDVG-GPVLDSVENLLGATQKTVIATGILNLWMHEPAEVAAR
MAV_0983|M.avium_104 LGFPALWIPDVG-GPVFDAVGHLLGATKRTVIATGILNLWMHSPAEVAES
TH_2753|M.thermoresistible__bu LGFPALWIPDVG-GPVLDSVQNLLGATKRTVIATGILNLWMHEPADVAAG
MMAR_1083|M.marinum_M LGYGAAWIGASP-DADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAAS
MUL_0841|M.ulcerans_Agy99 LAYGAAWIGASP-DADLAWVEPASEQTTSLQLATGIVNICSAPADEVAAS
Mb3492|M.bovis_AF2122/97 LGYGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAES
Rv3463|M.tuberculosis_H37Rv LGYGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAES
MSMEG_1514|M.smegmatis_MC2_155 LGYGAVWVGGSP-PAELEWVEPILEATTTLQVATGIVNIWTAAPGPVAES
MAB_3778|M.abscessus_ATCC_1997 LGYGSVWVGGVF-TADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAA
MLBr_00348|M.leprae_Br4923 AGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMA
.: : : : * :.:.:::: *
Mvan_3854|M.vanbaalenii_PYR-1 YAALTETHGERFLLGIGVSHAPLIDSNEPGRYRKPLAATKAFLDGI----
Mflv_2688|M.gilvum_PYR-GCK YATLTDKHGERFLLGIGVSHAPLIDSKEPGLYRKPLAATEKFLDAI----
MAV_0983|M.avium_104 YAALTAEHGDRFLLGIGVSHAPLIDAGQPGRYRKPLAATARFLDGL----
TH_2753|M.thermoresistible__bu YAQLTADHGDRFLLGIGVSHAPLINSREPGRYRRPLAATSAFLDGL----
MMAR_1083|M.marinum_M YQRIESAHPGRFLLGVGVGHPEHTQ-----EYQKPYDALVAYLDDL----
MUL_0841|M.ulcerans_Agy99 YQRIESAHPGRFLLGVGVGHPEHTQ-----EYQKPYDALVAYLDDL----
Mb3492|M.bovis_AF2122/97 FHRIEAAYPGRFLLGIGVGHAEMIS-----EYRKPYNALVEYLDRL----
Rv3463|M.tuberculosis_H37Rv FHRIEAAYPGRFLLGIGVGHAEMIS-----EYRKPYNALVEYLDRL----
MSMEG_1514|M.smegmatis_MC2_155 FHRIEAACPGRFLLGIGVGHREAHV-----EYRKPLDALTDYLDKL----
MAB_3778|M.abscessus_ATCC_1997 FHRIEAAYPGRFLLGVGAGHPEASA-----EYRKPYDALVEYLDGL----
MLBr_00348|M.leprae_Br4923 ALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVW
: *.:**:*.. : :* ::* :
Mvan_3854|M.vanbaalenii_PYR-1 --------DASPQPVPTANR----------------------VLAALGPK
Mflv_2688|M.gilvum_PYR-GCK --------DASEQPVPKANR----------------------VLAALGPK
MAV_0983|M.avium_104 --------DGAPRPVPIERR----------------------VLAALGPK
TH_2753|M.thermoresistible__bu --------DSAATPVPMQNR----------------------VLAALGPK
MMAR_1083|M.marinum_M --------DKAM--VPDSRR----------------------VLAALGPR
MUL_0841|M.ulcerans_Agy99 --------DKAM--VPDSRR----------------------VLAALGPR
Mb3492|M.bovis_AF2122/97 --------DDYG--VPANRR----------------------VVAALGPR
Rv3463|M.tuberculosis_H37Rv --------DDYG--VPANRR----------------------VVAALGPR
MSMEG_1514|M.smegmatis_MC2_155 --------DSYG--VPKHRR----------------------VVAALGPK
MAB_3778|M.abscessus_ATCC_1997 --------DAAG--VPKERR----------------------VLAALGPK
MLBr_00348|M.leprae_Br4923 AREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPK
* :* ::.* **:
Mvan_3854|M.vanbaalenii_PYR-1 MLQLSATRAGGAHPYLTTPEHTRQAREVLGS------------GPLLLPE
Mflv_2688|M.gilvum_PYR-GCK MLQLSATKAGGAHPYLSTPTHTAQAREVLGD------------GPLLLPE
MAV_0983|M.avium_104 MLKLSASRAGGAHPYLVTPDHTASARATLGH------------GPLLLPE
TH_2753|M.thermoresistible__bu MLTLAAERSRGAHPYLTTPEHTARARETLGE------------GPLLLPE
MMAR_1083|M.marinum_M MLRLAAQRSAGAHPYLTTPEHTGTARQLVGN------------TVFLAPE
MUL_0841|M.ulcerans_Agy99 MLRLAAQRSAGAHPYLTTPEHTGTARQLVGN------------TVFLAPE
Mb3492|M.bovis_AF2122/97 VLGLSARRSAGAHPYLTTPEHTARARELIGP------------SAFLAPE
Rv3463|M.tuberculosis_H37Rv VLGLSARRSAGAHPYLTTPEHTARARELIGP------------SAFLAPE
MSMEG_1514|M.smegmatis_MC2_155 VLQLSAEHSAGAHPYLTTPEHTRSAREIIGP------------DAFLAPE
MAB_3778|M.abscessus_ATCC_1997 VLKLSADRTAGAHPYLTTPEHTRQAREIIGP------------DALLVPE
MLBr_00348|M.leprae_Br4923 NVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICAS
: *:* * * : :* : . :. : ..
Mvan_3854|M.vanbaalenii_PYR-1 QSVLLTDDRDQAREVGIDWLRSYLA------LPNYANNLLRLGFSE----
Mflv_2688|M.gilvum_PYR-GCK QTVLLTDDRDKAREIGTDWLRSYLA------LPNYANNLLRLGFTE----
MAV_0983|M.avium_104 QTVILTDSAEEARRIGTDWLRAYLA------LPNYANNLLRSGFSE----
TH_2753|M.thermoresistible__bu QTVILSADRDEARSIGIPWLRGYLA------MPNYANNMLRSGFTD----
MMAR_1083|M.marinum_M HKVVLTTDAAQARAVGRKFIDFYLG------LSNYVNNWLKLGFTE----
MUL_0841|M.ulcerans_Agy99 HKVVLTTDAAQASAVDRKFIDFYLG------LSNYVNNWLKLGFTE----
Mb3492|M.bovis_AF2122/97 HKVVLTTDSARARTVGRQALDMYFN------LANYRNNWKRLGFTD----
Rv3463|M.tuberculosis_H37Rv HKVVLTTDSARARTVGRQALDMYFN------LANYRNNWKRLGFTD----
MSMEG_1514|M.smegmatis_MC2_155 HKVVLTTDAEQARAVGRKALDLYLG------LANYLNNFKRLGFTD----
MAB_3778|M.abscessus_ATCC_1997 HKVVLSTDAPSAREIGRRTVDFYLT------LSNYVNNWKRLGFND----
MLBr_00348|M.leprae_Br4923 AQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDE
:::: . * : *: : : : *: :
Mvan_3854|M.vanbaalenii_PYR-1 ----------DDVSS-VSDRLFDALIAWGDEDAVRRRVQEHLDAGADHVC
Mflv_2688|M.gilvum_PYR-GCK ----------EDLSS-VSDRVFDALIAWGDEDAVRSRVQEHLDAGANHVC
MAV_0983|M.avium_104 ----------DDLSQ-VSDRLFNAIIAWGDEEAVMRRVAEHRSAGADHVC
TH_2753|M.thermoresistible__bu ----------EDVQT-VSDRLFDALIAWGDEETVLGRVREHQSAGADHVC
MMAR_1083|M.marinum_M ----------DDVRKPGSDRLIDALVAYGTPDQIARRLGEHLEAGADHVA
MUL_0841|M.ulcerans_Agy99 ----------DDVRKPGSDRLIDALVAYGTPDQIARRLGEHHEAGADHVA
Mb3492|M.bovis_AF2122/97 ----------DEVSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVP
Rv3463|M.tuberculosis_H37Rv ----------DEVSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVP
MSMEG_1514|M.smegmatis_MC2_155 ----------DELAKPGADRFIDAVVAYGTVDAIAARLSEHLAAGADHVP
MAB_3778|M.abscessus_ATCC_1997 ----------EDLTSPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVL
MLBr_00348|M.leprae_Br4923 VTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMM
:. .: ..:: : * : :: **. :
Mvan_3854|M.vanbaalenii_PYR-1 VQVLTADPREFPREQWRRLAEALL---
Mflv_2688|M.gilvum_PYR-GCK VQVLTADPREFPREQWRRLAAALL---
MAV_0983|M.avium_104 VQVLLADPTAFPREEWRRIAAASR---
TH_2753|M.thermoresistible__bu VQVLGADQQAFPREQWRRLAAALR---
MMAR_1083|M.marinum_M IQVLRPSREDKPMAALTELSGALGLTR
MUL_0841|M.ulcerans_Agy99 IQVLRPSREDKSMAALTELSGALGLTR
Mb3492|M.bovis_AF2122/97 IQVLTE--DDNLVSALTELAKPLRLT-
Rv3463|M.tuberculosis_H37Rv IQVLTE--DDNLVSALTELAKPLRLT-
MSMEG_1514|M.smegmatis_MC2_155 VQVLTS--PDKLVPALAELAGPLGLA-
MAB_3778|M.abscessus_ATCC_1997 IQVLGD---KGLVDTLTSLADALR---
MLBr_00348|M.leprae_Br4923 VS-------ASSVEQVRDLAGLF----
:. ::