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TNAVSLKPELGRFGVWLGSRSITPELAGQIESLAYGAAWIGASPDADLAWVEPASEQTTSLQLATGIVNI CSAPADEVAASYQRIESAHPGRFLLGVGVGHPEHTQEYQKPYDALVAYLDDLDKAMVPDSRRVLAALGPR MLRLAAQRSAGAHPYLTTPEHTGTARQLVGNTVFLAPEHKVVLTTDAAQASAVDRKFIDFYLGLSNYVNN WLKLGFTEDDVRKPGSDRLIDALVAYGTPDQIARRLGEHHEAGADHVAIQVLRPSREDKSMAALTELSGA LGLTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0841 | - | - | 100% (286) | hypothetical protein MUL_0841 |
| M. ulcerans Agy99 | MUL_0842 | - | 9e-97 | 63.21% (280) | hypothetical protein MUL_0842 |
| M. ulcerans Agy99 | MUL_4079 | - | 2e-06 | 22.29% (341) | coenzyme F420-dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 1e-97 | 62.28% (289) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5006 | - | 1e-106 | 68.18% (286) | hypothetical protein Mflv_5006 |
| M. tuberculosis H37Rv | Rv3463 | - | 1e-97 | 62.28% (289) | hypothetical protein Rv3463 |
| M. leprae Br4923 | MLBr_00348 | - | 4e-05 | 21.17% (326) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3778 | - | 4e-88 | 59.12% (274) | hypothetical protein MAB_3778 |
| M. marinum M | MMAR_1083 | - | 1e-158 | 97.55% (286) | hypothetical protein MMAR_1083 |
| M. avium 104 | MAV_4405 | - | 1e-116 | 72.03% (286) | hypothetical protein MAV_4405 |
| M. smegmatis MC2 155 | MSMEG_1513 | - | 1e-102 | 65.85% (284) | hypothetical protein MSMEG_1513 |
| M. thermoresistible (build 8) | TH_0027 | - | 2e-99 | 68.06% (263) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_1367 | - | 1e-105 | 67.86% (280) | hypothetical protein Mvan_1367 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3492|M.bovis_AF2122/97 MTNCAAGKPSSGPNLGRFGSFGR--GVTPQQATEIEALGYGAVWVGGSP-
Rv3463|M.tuberculosis_H37Rv MTNCAAGKPSSGPNLGRFGSFGR--GVTPQQATEIEALGYGAVWVGGSP-
MUL_0841|M.ulcerans_Agy99 MT----NAVSLKPELGRFGVWLGSRSITPELAGQIESLAYGAAWIGASP-
MMAR_1083|M.marinum_M MT----NAVSLKPELGRFGVWLGSRSITPELAGQIESLGYGAAWIGASP-
MAV_4405|M.avium_104 MT----EGVSLKPDLGPFGVWLSTRSITAELAARIESLGYGAAWIGGSP-
MSMEG_1513|M.smegmatis_MC2_155 MT----DALSLKPNLGRYGVWTA-GAVTPKQAAEIEKLGYGAVWIGGSP-
TH_0027|M.thermoresistible__bu MT----DAVSLKPDLGRFGVWTG-GPIPRELAAEIEKLGYRALWVGGSP-
Mflv_5006|M.gilvum_PYR-GCK MTN--SEGPSLKPALGRFGVWTG-EPATPDQAVEIEKLGYGTVWVGASP-
Mvan_1367|M.vanbaalenii_PYR-1 MTA--SEGPSLKPALGRFGVWTG-APVSPDQAVEIEKLGYGTVWVGASP-
MAB_3778|M.abscessus_ATCC_1997 MG---------ESKLNRYGVWKG-GPVTPEQARTIEDLGYGSVWVGGVF-
MLBr_00348|M.leprae_Br4923 MVER-ANAMKLGLQLGYWAAQPP--GNAAELVAAAEGAGFDAVFTGEAWG
* *. :. . . . * .: : : *
Mb3492|M.bovis_AF2122/97 PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRIEAAYPGRFL
Rv3463|M.tuberculosis_H37Rv PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRIEAAYPGRFL
MUL_0841|M.ulcerans_Agy99 DADLAWVEPASEQTTSLQLATGIVNICSAPADEVAASYQRIESAHPGRFL
MMAR_1083|M.marinum_M DADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAASYQRIESAHPGRFL
MAV_4405|M.avium_104 DAELSWVDPALAGTTSLHLATGIVNIWSAPAAAVAESFHRIESGHPGRFL
MSMEG_1513|M.smegmatis_MC2_155 AADLSSVEPILENTETLQVATGIVNIWASDANTVAESFHRIEKAHPGRFV
TH_0027|M.thermoresistible__bu AAELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFHRIEKAYPGRFV
Mflv_5006|M.gilvum_PYR-GCK AADLAFVEPILEKTETLQVATGIVNIWTADADEVAESYHRIEKAFPGRFL
Mvan_1367|M.vanbaalenii_PYR-1 AADLAFVEPILEKTRSLQVATGIVNIWTADAAEVSESYHRIEKAFPGRFL
MAB_3778|M.abscessus_ATCC_1997 TADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAAFHRIEAAYPGRFL
MLBr_00348|M.leprae_Br4923 SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHI
: * : :.:.:*:: : : : :: **.:
Mb3492|M.bovis_AF2122/97 LGIGVGHAEMIS-----EYRKPYNALVEYLDRLDDYGVPAN---------
Rv3463|M.tuberculosis_H37Rv LGIGVGHAEMIS-----EYRKPYNALVEYLDRLDDYGVPAN---------
MUL_0841|M.ulcerans_Agy99 LGVGVGHPEHTQ-----EYQKPYDALVAYLDDLDKAMVPDS---------
MMAR_1083|M.marinum_M LGVGVGHPEHTQ-----EYQKPYDALVAYLDDLDKAMVPDS---------
MAV_4405|M.avium_104 LGIGAGHREHTR-----EYVKPYDAVVSYLDELDAAVIPTS---------
MSMEG_1513|M.smegmatis_MC2_155 LGVGVGHPEHTG-----EYRKPYDALVEYLDVLDAAKVPTS---------
TH_0027|M.thermoresistible__bu LGLGVGHPEATE-----EYAKPYEAMVTYLDVLDEATVPTS---------
Mflv_5006|M.gilvum_PYR-GCK LGVGVGHPEHTQ-----EYTKPYQALVDYLDKLDAAKVPTS---------
Mvan_1367|M.vanbaalenii_PYR-1 LGIGVGHPEHTQ-----EYVKPYQALVDYLDKLDAAKVPTS---------
MAB_3778|M.abscessus_ATCC_1997 LGVGAGHPEASA-----EYRKPYDALVEYLDGLDAAGVPKE---------
MLBr_00348|M.leprae_Br4923 LGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHY
**:*.. : : ** . *:* :
Mb3492|M.bovis_AF2122/97 ---------------------------RRVVAALGPRVLGLSARRSAGAH
Rv3463|M.tuberculosis_H37Rv ---------------------------RRVVAALGPRVLGLSARRSAGAH
MUL_0841|M.ulcerans_Agy99 ---------------------------RRVLAALGPRMLRLAAQRSAGAH
MMAR_1083|M.marinum_M ---------------------------RRVLAALGPRMLRLAAQRSAGAH
MAV_4405|M.avium_104 ---------------------------RRVLAALGPRMLRLAAQRSAGAH
MSMEG_1513|M.smegmatis_MC2_155 ---------------------------RRVLAALGDKVLKLSAARSAGAH
TH_0027|M.thermoresistible__bu ---------------------------RRVLAALGPRMLQLAAQRSAGAH
Mflv_5006|M.gilvum_PYR-GCK ---------------------------RMVVAALGPKVLKLAAQRSAGAH
Mvan_1367|M.vanbaalenii_PYR-1 ---------------------------RRVVAALGPKVLQLAAQRSAGAH
MAB_3778|M.abscessus_ATCC_1997 ---------------------------RRVLAALGPKVLKLSADRTAGAH
MLBr_00348|M.leprae_Br4923 PLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
::.* * : : *:* *
Mb3492|M.bovis_AF2122/97 PYLTTPEHTARARELIGP------------SAFLAPEHKVVLTTDSARAR
Rv3463|M.tuberculosis_H37Rv PYLTTPEHTARARELIGP------------SAFLAPEHKVVLTTDSARAR
MUL_0841|M.ulcerans_Agy99 PYLTTPEHTGTARQLVGN------------TVFLAPEHKVVLTTDAAQAS
MMAR_1083|M.marinum_M PYLTTPEHTGTARQLVGN------------TVFLAPEHKVVLTTDAAQAR
MAV_4405|M.avium_104 PFLTTPEHTAKARELVGG------------SVFLAPAHKVVLTTDRDRAR
MSMEG_1513|M.smegmatis_MC2_155 PYLTTPEHTEHARAVLGE------------AVFLAPEHKVVLNTDAAAAR
TH_0027|M.thermoresistible__bu PYLTTPQHTGQARNRIGP------------SVFLAPEHKVVLDTDAAAAR
Mflv_5006|M.gilvum_PYR-GCK PYLTTPVHTGQARELLGP------------TVLIAPEHKVVLTDDAEKAR
Mvan_1367|M.vanbaalenii_PYR-1 PYLTTPVHTGQARELLGP------------TVLIAPEHKVVLTNDADKAR
MAB_3778|M.abscessus_ATCC_1997 PYLTTPEHTRQAREIIGP------------DALLVPEHKVVLSTDAPSAR
MLBr_00348|M.leprae_Br4923 PIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAF
* : :* : . :. : . ::*: * *
Mb3492|M.bovis_AF2122/97 TVGRQALDMYFN------LANYRNNWKRLGFTD--------------DEV
Rv3463|M.tuberculosis_H37Rv TVGRQALDMYFN------LANYRNNWKRLGFTD--------------DEV
MUL_0841|M.ulcerans_Agy99 AVDRKFIDFYLG------LSNYVNNWLKLGFTE--------------DDV
MMAR_1083|M.marinum_M AVGRKFIDFYLG------LSNYVNNWLKLGFTE--------------DDV
MAV_4405|M.avium_104 AAGRQAIEHNLG------LSNYVHNWLRLGFTE--------------ADV
MSMEG_1513|M.smegmatis_MC2_155 ALGRKTVEFYLD------LSNYVNNWRKLGFTD--------------SDV
TH_0027|M.thermoresistible__bu EIGRQTIGFYLR------LRNYVNNWKQLGFTD--------------DDI
Mflv_5006|M.gilvum_PYR-GCK EIGRGTVDFYLG------LSNYVNNWKRLGFTE--------------EDL
Mvan_1367|M.vanbaalenii_PYR-1 EIGRGTVDFYLG------LSNYLNNWKRLGFTD--------------EDL
MAB_3778|M.abscessus_ATCC_1997 EIGRRTVDFYLT------LSNYVNNWKRLGFND--------------EDL
MLBr_00348|M.leprae_Br4923 AGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKA
: : : : . : ::*: : .
Mb3492|M.bovis_AF2122/97 SRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTED--DNLV
Rv3463|M.tuberculosis_H37Rv SRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTED--DNLV
MUL_0841|M.ulcerans_Agy99 RKPGSDRLIDALVAYGTPDQIARRLGEHHEAGADHVAIQVLRPSREDKSM
MMAR_1083|M.marinum_M RKPGSDRLIDALVAYGTPDQIARRLGEHLEAGADHVAIQVLRPSREDKPM
MAV_4405|M.avium_104 RPPGSDRLIDAVIGYGTPQAVAARLREHLDAGADHVAIQVLGGDSEETLL
MSMEG_1513|M.smegmatis_MC2_155 EKPGSDKLIDAVVAHGTAGDIAARLRQHIAAGADHVSIQVLGEP--EDLI
TH_0027|M.thermoresistible__bu AEPGSDELIDAMVAHGTAEQVADALREHLDRGADHVAIQVLGGR--ERLL
Mflv_5006|M.gilvum_PYR-GCK ERPGSDRFIDAVVAYGSPDEIAARLSEHLAAGADHVAIQVLGGG--DELL
Mvan_1367|M.vanbaalenii_PYR-1 TRPGSDRFIDAVVAHGSPDEIAARLTEHLAAGADHVAIQVLGGS--DELL
MAB_3778|M.abscessus_ATCC_1997 TSPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVLIQVLGDK---GLV
MLBr_00348|M.leprae_Br4923 AEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLA
.: ::*: : * :. : *. : :..
Mb3492|M.bovis_AF2122/97 SALT--ELAKP---------------LRLT--------------
Rv3463|M.tuberculosis_H37Rv SALT--ELAKP---------------LRLT--------------
MUL_0841|M.ulcerans_Agy99 AALT--ELSGA---------------LGLTR-------------
MMAR_1083|M.marinum_M AALT--ELSGA---------------LGLTR-------------
MAV_4405|M.avium_104 PALT--ELADA---------------LGLTRTN-----------
MSMEG_1513|M.smegmatis_MC2_155 PTLT--ELAGP---------------LELKN-------------
TH_0027|M.thermoresistible__bu PTLXXSPRCGPNWGRCTSWSRARVWWTSPRSPRSAGRPGSGSSM
Mflv_5006|M.gilvum_PYR-GCK STLE--ELAGP---------------LDLKAAD-----------
Mvan_1367|M.vanbaalenii_PYR-1 STLE--ELAGP---------------LGLTA-------------
MAB_3778|M.abscessus_ATCC_1997 DTLT--SLADA-----------------LR--------------
MLBr_00348|M.leprae_Br4923 GLF-----------------------------------------
: