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NLSGVGLWSSQLRYGNPEEAAEAAAELDGLGFTALWIPDVGGPVLDSVENLLGATQKTVIATGILNLWMH EPAEVAARYATLTDKHGERFLLGIGVSHAPLIDSKEPGLYRKPLAATEKFLDAIDASEQPVPKANRVLAA LGPKMLQLSATKAGGAHPYLSTPTHTAQAREVLGDGPLLLPEQTVLLTDDRDKAREIGTDWLRSYLALPN YANNLLRLGFTEEDLSSVSDRVFDALIAWGDEDAVRSRVQEHLDAGANHVCVQVLTADPREFPREQWRRL AAALL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_2688 | - | - | 100% (286) | hypothetical protein Mflv_2688 |
M. gilvum PYR-GCK | Mflv_5005 | - | 6e-56 | 44.87% (263) | hypothetical protein Mflv_5005 |
M. gilvum PYR-GCK | Mflv_5006 | - | 2e-55 | 44.91% (265) | hypothetical protein Mflv_5006 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3492 | - | 1e-54 | 45.56% (248) | hypothetical protein Mb3492 |
M. tuberculosis H37Rv | Rv3463 | - | 1e-54 | 45.56% (248) | hypothetical protein Rv3463 |
M. leprae Br4923 | MLBr_00348 | - | 9e-09 | 24.40% (209) | putative coenzyme F420-dependent oxidoreductase |
M. abscessus ATCC 19977 | MAB_3778 | - | 1e-53 | 44.15% (265) | hypothetical protein MAB_3778 |
M. marinum M | MMAR_1083 | - | 2e-54 | 41.90% (284) | hypothetical protein MMAR_1083 |
M. avium 104 | MAV_0983 | - | 1e-124 | 74.30% (284) | hypothetical protein MAV_0983 |
M. smegmatis MC2 155 | MSMEG_1514 | - | 2e-54 | 46.43% (252) | hypothetical protein MSMEG_1514 |
M. thermoresistible (build 8) | TH_2753 | - | 1e-125 | 75.09% (285) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_0841 | - | 2e-48 | 39.44% (284) | hypothetical protein MUL_0841 |
M. vanbaalenii PYR-1 | Mvan_3854 | - | 1e-149 | 89.16% (286) | hypothetical protein Mvan_3854 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2688|M.gilvum_PYR-GCK MN----------LSGVGLWS------SQLRYGNPE----EAAEAAAELDG Mvan_3854|M.vanbaalenii_PYR-1 MN----------LSGVGLWS------SQLRYGNPD----EAADAAAELDG MAV_0983|M.avium_104 ME----------LTGVGIWS------SQLRYGDPA----ESADAAAELDE TH_2753|M.thermoresistible__bu VN----------LEGVGIWS------SQLRYGDQA----EAAEAAAELEE MMAR_1083|M.marinum_M MT-----------NAVSLKP------ELGRFGVWLGSRSITPELAGQIES MUL_0841|M.ulcerans_Agy99 MT-----------NAVSLKP------ELGRFGVWLGSRSITPELAGQIES Mb3492|M.bovis_AF2122/97 MT-----------NCAAGKPSSGP--NLGRFGSFG--RGVTPQQATEIEA Rv3463|M.tuberculosis_H37Rv MT-----------NCAAGKPSSGP--NLGRFGSFG--RGVTPQQATEIEA MSMEG_1514|M.smegmatis_MC2_155 MTGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFG--RGVTPAQAKEIEA MAB_3778|M.abscessus_ATCC_1997 MG----------------ES------KLNRYGVWKG-GPVTPEQARTIED MLBr_00348|M.leprae_Br4923 --------------MVERANAMKLGLQLGYWAAQPP--GNAAELVAAAEG . :. :. . : Mflv_2688|M.gilvum_PYR-GCK LGFTALWIPDVG-GPVLDSVENLLGATQKTVIATGILNLWMHEPAEVAAR Mvan_3854|M.vanbaalenii_PYR-1 LGFTALWIPDVG-GPVLDSVDNLLSATEKTVIATGILNLWMHEPAEVAAR MAV_0983|M.avium_104 LGFPALWIPDVG-GPVFDAVGHLLGATKRTVIATGILNLWMHSPAEVAES TH_2753|M.thermoresistible__bu LGFPALWIPDVG-GPVLDSVQNLLGATKRTVIATGILNLWMHEPADVAAG MMAR_1083|M.marinum_M LGYGAAWIGASP-DADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAAS MUL_0841|M.ulcerans_Agy99 LAYGAAWIGASP-DADLAWVEPASEQTTSLQLATGIVNICSAPADEVAAS Mb3492|M.bovis_AF2122/97 LGYGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAES Rv3463|M.tuberculosis_H37Rv LGYGAVWVGGSP-PAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAES MSMEG_1514|M.smegmatis_MC2_155 LGYGAVWVGGSP-PAELEWVEPILEATTTLQVATGIVNIWTAAPGPVAES MAB_3778|M.abscessus_ATCC_1997 LGYGSVWVGGVF-TADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAA MLBr_00348|M.leprae_Br4923 AGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMA .: : : : * :.:.:::: * Mflv_2688|M.gilvum_PYR-GCK YATLTDKHGERFLLGIGVSHAPLIDSKEPGLYRKPLAATEKFLDAI---- Mvan_3854|M.vanbaalenii_PYR-1 YAALTETHGERFLLGIGVSHAPLIDSNEPGRYRKPLAATKAFLDGI---- MAV_0983|M.avium_104 YAALTAEHGDRFLLGIGVSHAPLIDAGQPGRYRKPLAATARFLDGL---- TH_2753|M.thermoresistible__bu YAQLTADHGDRFLLGIGVSHAPLINSREPGRYRRPLAATSAFLDGL---- MMAR_1083|M.marinum_M YQRIESAHPGRFLLGVGVGHPEHTQ-----EYQKPYDALVAYLDDL---- MUL_0841|M.ulcerans_Agy99 YQRIESAHPGRFLLGVGVGHPEHTQ-----EYQKPYDALVAYLDDL---- Mb3492|M.bovis_AF2122/97 FHRIEAAYPGRFLLGIGVGHAEMIS-----EYRKPYNALVEYLDRL---- Rv3463|M.tuberculosis_H37Rv FHRIEAAYPGRFLLGIGVGHAEMIS-----EYRKPYNALVEYLDRL---- MSMEG_1514|M.smegmatis_MC2_155 FHRIEAACPGRFLLGIGVGHREAHV-----EYRKPLDALTDYLDKL---- MAB_3778|M.abscessus_ATCC_1997 FHRIEAAYPGRFLLGVGAGHPEASA-----EYRKPYDALVEYLDGL---- MLBr_00348|M.leprae_Br4923 ALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVW : *.:**:*.. : :* ::* : Mflv_2688|M.gilvum_PYR-GCK --------DASEQPVPKANR----------------------VLAALGPK Mvan_3854|M.vanbaalenii_PYR-1 --------DASPQPVPTANR----------------------VLAALGPK MAV_0983|M.avium_104 --------DGAPRPVPIERR----------------------VLAALGPK TH_2753|M.thermoresistible__bu --------DSAATPVPMQNR----------------------VLAALGPK MMAR_1083|M.marinum_M --------DKAM--VPDSRR----------------------VLAALGPR MUL_0841|M.ulcerans_Agy99 --------DKAM--VPDSRR----------------------VLAALGPR Mb3492|M.bovis_AF2122/97 --------DDYG--VPANRR----------------------VVAALGPR Rv3463|M.tuberculosis_H37Rv --------DDYG--VPANRR----------------------VVAALGPR MSMEG_1514|M.smegmatis_MC2_155 --------DSYG--VPKHRR----------------------VVAALGPK MAB_3778|M.abscessus_ATCC_1997 --------DAAG--VPKERR----------------------VLAALGPK MLBr_00348|M.leprae_Br4923 AREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPK * :* ::.* **: Mflv_2688|M.gilvum_PYR-GCK MLQLSATKAGGAHPYLSTPTHTAQAREVLGD------------GPLLLPE Mvan_3854|M.vanbaalenii_PYR-1 MLQLSATRAGGAHPYLTTPEHTRQAREVLGS------------GPLLLPE MAV_0983|M.avium_104 MLKLSASRAGGAHPYLVTPDHTASARATLGH------------GPLLLPE TH_2753|M.thermoresistible__bu MLTLAAERSRGAHPYLTTPEHTARARETLGE------------GPLLLPE MMAR_1083|M.marinum_M MLRLAAQRSAGAHPYLTTPEHTGTARQLVGN------------TVFLAPE MUL_0841|M.ulcerans_Agy99 MLRLAAQRSAGAHPYLTTPEHTGTARQLVGN------------TVFLAPE Mb3492|M.bovis_AF2122/97 VLGLSARRSAGAHPYLTTPEHTARARELIGP------------SAFLAPE Rv3463|M.tuberculosis_H37Rv VLGLSARRSAGAHPYLTTPEHTARARELIGP------------SAFLAPE MSMEG_1514|M.smegmatis_MC2_155 VLQLSAEHSAGAHPYLTTPEHTRSAREIIGP------------DAFLAPE MAB_3778|M.abscessus_ATCC_1997 VLKLSADRTAGAHPYLTTPEHTRQAREIIGP------------DALLVPE MLBr_00348|M.leprae_Br4923 NVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICAS : *:* * * : :* : . :. : .. Mflv_2688|M.gilvum_PYR-GCK QTVLLTDDRDKAREIGTDWLRSYLA------LPNYANNLLRLGFTE---- Mvan_3854|M.vanbaalenii_PYR-1 QSVLLTDDRDQAREVGIDWLRSYLA------LPNYANNLLRLGFSE---- MAV_0983|M.avium_104 QTVILTDSAEEARRIGTDWLRAYLA------LPNYANNLLRSGFSE---- TH_2753|M.thermoresistible__bu QTVILSADRDEARSIGIPWLRGYLA------MPNYANNMLRSGFTD---- MMAR_1083|M.marinum_M HKVVLTTDAAQARAVGRKFIDFYLG------LSNYVNNWLKLGFTE---- MUL_0841|M.ulcerans_Agy99 HKVVLTTDAAQASAVDRKFIDFYLG------LSNYVNNWLKLGFTE---- Mb3492|M.bovis_AF2122/97 HKVVLTTDSARARTVGRQALDMYFN------LANYRNNWKRLGFTD---- Rv3463|M.tuberculosis_H37Rv HKVVLTTDSARARTVGRQALDMYFN------LANYRNNWKRLGFTD---- MSMEG_1514|M.smegmatis_MC2_155 HKVVLTTDAEQARAVGRKALDLYLG------LANYLNNFKRLGFTD---- MAB_3778|M.abscessus_ATCC_1997 HKVVLSTDAPSAREIGRRTVDFYLT------LSNYVNNWKRLGFND---- MLBr_00348|M.leprae_Br4923 AQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDE :::: . * : *: : : : *: : Mflv_2688|M.gilvum_PYR-GCK ----------EDLSS-VSDRVFDALIAWGDEDAVRSRVQEHLDAGANHVC Mvan_3854|M.vanbaalenii_PYR-1 ----------DDVSS-VSDRLFDALIAWGDEDAVRRRVQEHLDAGADHVC MAV_0983|M.avium_104 ----------DDLSQ-VSDRLFNAIIAWGDEEAVMRRVAEHRSAGADHVC TH_2753|M.thermoresistible__bu ----------EDVQT-VSDRLFDALIAWGDEETVLGRVREHQSAGADHVC MMAR_1083|M.marinum_M ----------DDVRKPGSDRLIDALVAYGTPDQIARRLGEHLEAGADHVA MUL_0841|M.ulcerans_Agy99 ----------DDVRKPGSDRLIDALVAYGTPDQIARRLGEHHEAGADHVA Mb3492|M.bovis_AF2122/97 ----------DEVSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVP Rv3463|M.tuberculosis_H37Rv ----------DEVSRPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVP MSMEG_1514|M.smegmatis_MC2_155 ----------DELAKPGADRFIDAVVAYGTVDAIAARLSEHLAAGADHVP MAB_3778|M.abscessus_ATCC_1997 ----------EDLTSPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVL MLBr_00348|M.leprae_Br4923 VTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMM :. .: ..:: : * : :: **. : Mflv_2688|M.gilvum_PYR-GCK VQVLTADPREFPREQWRRLAAALL--- Mvan_3854|M.vanbaalenii_PYR-1 VQVLTADPREFPREQWRRLAEALL--- MAV_0983|M.avium_104 VQVLLADPTAFPREEWRRIAAASR--- TH_2753|M.thermoresistible__bu VQVLGADQQAFPREQWRRLAAALR--- MMAR_1083|M.marinum_M IQVLRPSREDKPMAALTELSGALGLTR MUL_0841|M.ulcerans_Agy99 IQVLRPSREDKSMAALTELSGALGLTR Mb3492|M.bovis_AF2122/97 IQVLTE--DDNLVSALTELAKPLRLT- Rv3463|M.tuberculosis_H37Rv IQVLTE--DDNLVSALTELAKPLRLT- MSMEG_1514|M.smegmatis_MC2_155 VQVLTS--PDKLVPALAELAGPLGLA- MAB_3778|M.abscessus_ATCC_1997 IQVLGD---KGLVDTLTSLADALR--- MLBr_00348|M.leprae_Br4923 VS-------ASSVEQVRDLAGLF---- :. ::