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TGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFGRGVTPAQAKEIEALGYGAVWVGGSPPAELEWVEPIL EATTTLQVATGIVNIWTAAPGPVAESFHRIEAACPGRFLLGIGVGHREAHVEYRKPLDALTDYLDKLDSY GVPKHRRVVAALGPKVLQLSAEHSAGAHPYLTTPEHTRSAREIIGPDAFLAPEHKVVLTTDAEQARAVGR KALDLYLGLANYLNNFKRLGFTDDELAKPGADRFIDAVVAYGTVDAIAARLSEHLAAGADHVPVQVLTSP DKLVPALAELAGPLGLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1514 | - | - | 100% (298) | hypothetical protein MSMEG_1514 |
| M. smegmatis MC2 155 | MSMEG_4141 | - | e-107 | 65.65% (294) | hypothetical protein MSMEG_4141 |
| M. smegmatis MC2 155 | MSMEG_1513 | - | e-102 | 66.43% (280) | hypothetical protein MSMEG_1513 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 1e-120 | 76.62% (278) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5005 | - | 1e-127 | 78.01% (282) | hypothetical protein Mflv_5005 |
| M. tuberculosis H37Rv | Rv3463 | - | 1e-120 | 76.62% (278) | hypothetical protein Rv3463 |
| M. leprae Br4923 | MLBr_00131 | - | 3e-05 | 24.69% (239) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3778 | - | 1e-94 | 65.06% (269) | hypothetical protein MAB_3778 |
| M. marinum M | MMAR_1084 | - | 1e-123 | 76.84% (285) | hypothetical protein MMAR_1084 |
| M. avium 104 | MAV_4404 | - | 1e-132 | 82.80% (279) | hypothetical protein MAV_4404 |
| M. thermoresistible (build 8) | TH_0027 | - | 1e-94 | 63.10% (271) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0842 | - | 1e-125 | 77.27% (286) | hypothetical protein MUL_0842 |
| M. vanbaalenii PYR-1 | Mvan_1368 | - | 1e-135 | 85.71% (273) | hypothetical protein Mvan_1368 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5005|M.gilvum_PYR-GCK -------------------MSDVT------PDLGRFGSFGRG-VTPEQAQ
Mvan_1368|M.vanbaalenii_PYR-1 -------------------MTDTK------PDLGRFGSFGRG-VTPQQAK
MSMEG_1514|M.smegmatis_MC2_155 -----MTGIPREGGGVEADMTDTTPAAGPKPDLGRYGSFGRG-VTPAQAK
MMAR_1084|M.marinum_M ----------MPDPETDSDARSSASPVAGKPNLGRFGSFGRG-VTPAQAR
MUL_0842|M.ulcerans_Agy99 ----------MPAPETDSDARSSASPAAGKPNLGRFGSFGRG-VTPAQAR
MAV_4404|M.avium_104 -----------------------MTQAAGKPDLGRFGSFGRG-VTPQQAK
Mb3492|M.bovis_AF2122/97 ------------------MTNCAAGKPSSGPNLGRFGSFGRG-VTPQQAT
Rv3463|M.tuberculosis_H37Rv ------------------MTNCAAGKPSSGPNLGRFGSFGRG-VTPQQAT
MAB_3778|M.abscessus_ATCC_1997 ---------------------------MGESKLNRYGVWKGGPVTPEQAR
TH_0027|M.thermoresistible__bu ----------------------MTDAVSLKPDLGRFGVWTGGPIPRELAA
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPR
. *. . : . : .
Mflv_5005|M.gilvum_PYR-GCK QIEALGYGAVWVGGSPPAELDWVEPLLAA-------TTTLQVATGIVNIW
Mvan_1368|M.vanbaalenii_PYR-1 DIEALGYGAVWVGGSPPAELDWVEPLLDA-------TTTLQVATGIVNIW
MSMEG_1514|M.smegmatis_MC2_155 EIEALGYGAVWVGGSPPAELEWVEPILEA-------TTTLQVATGIVNIW
MMAR_1084|M.marinum_M DIEALGYGAVWVGGSPPAELAWVEPILAA-------TTTLQVATGIVNIW
MUL_0842|M.ulcerans_Agy99 DIEALGYGAVWVGGSPPAELAWVEPILAA-------TTTLQVATGIVNIW
MAV_4404|M.avium_104 DIEALGYGAVWVGGSPPAELAWVEPLLEA-------TTTLQVATGIVNIW
Mb3492|M.bovis_AF2122/97 EIEALGYGAVWVGGSPPAALSWVEPILQA-------TTTLCVATGIVNIW
Rv3463|M.tuberculosis_H37Rv EIEALGYGAVWVGGSPPAALSWVEPILQA-------TTTLCVATGIVNIW
MAB_3778|M.abscessus_ATCC_1997 TIEDLGYGSVWVGGVFTADLAYVEPLLAV-------TENLTVASGIVNIW
TH_0027|M.thermoresistible__bu EIEKLGYRALWVGGSPAAELDFVEPILEA-------TETLQVATGIVNIW
MLBr_00131|M.leprae_Br4923 SVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAG
: * .: . : : * :. :.:
Mflv_5005|M.gilvum_PYR-GCK TADAGPVAESFHRIESAHPGRFLLGIGVGHPEAHQQYR--------RPID
Mvan_1368|M.vanbaalenii_PYR-1 TAAAGPVAESFHRIEAAHPGRFLLGIGVGHPEAHQEYV--------KPLD
MSMEG_1514|M.smegmatis_MC2_155 TAAPGPVAESFHRIEAACPGRFLLGIGVGHREAHVEYR--------KPLD
MMAR_1084|M.marinum_M SAPAKPVAESFHRIEAAYPGRFLLGIGVGHPEAITEYHSTS-----NAVD
MUL_0842|M.ulcerans_Agy99 SAPAKPVAESFHRIEAAYPGRFLLGIGVGHPEAITEYHSTG-----NAVD
MAV_4404|M.avium_104 TAPAGPVAESFHRIEAAYPGRFLLGIGVGHPEAHTEYR--------KPYD
Mb3492|M.bovis_AF2122/97 SAPAQRVAESFHRIEAAYPGRFLLGIGVGHAEMISEYR--------KPYN
Rv3463|M.tuberculosis_H37Rv SAPAQRVAESFHRIEAAYPGRFLLGIGVGHAEMISEYR--------KPYN
MAB_3778|M.abscessus_ATCC_1997 TSPVDEIAAAFHRIEAAYPGRFLLGVGAGHPEASAEYR--------KPYD
TH_0027|M.thermoresistible__bu TAPARTVAQSFHRIEKAYPGRFVLGLGVGHPEATEEYA--------KPYE
MLBr_00131|M.leprae_Br4923 RRNPAVTAQAAATLHLLTRGKAMLGIGVGEREGNEPYGVEWTKPVARFQE
* : :. *: :**:*.*. * * . :
Mflv_5005|M.gilvum_PYR-GCK ALVEYLDKLDEYGVPRGRR-----------------------VVAALGPK
Mvan_1368|M.vanbaalenii_PYR-1 ALTDYLDKLDEYGVPRGRR-----------------------VVAALGPK
MSMEG_1514|M.smegmatis_MC2_155 ALTDYLDKLDSYGVPKHRR-----------------------VVAALGPK
MMAR_1084|M.marinum_M ALIEYLNRLDDYGVPANRR-----------------------VVAALGPR
MUL_0842|M.ulcerans_Agy99 ALIEYLNRLDDYGVPANRR-----------------------VVAALGPR
MAV_4404|M.avium_104 ALADYLTRLDQYGVPAGRR-----------------------VVAALGPR
Mb3492|M.bovis_AF2122/97 ALVEYLDRLDDYGVPANRR-----------------------VVAALGPR
Rv3463|M.tuberculosis_H37Rv ALVEYLDRLDDYGVPANRR-----------------------VVAALGPR
MAB_3778|M.abscessus_ATCC_1997 ALVEYLDGLDAAGVPKERR-----------------------VLAALGPK
TH_0027|M.thermoresistible__bu AMVTYLDVLDEATVPTSRR-----------------------VLAALGPR
MLBr_00131|M.leprae_Br4923 ALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAHGPR
*: * *. :** **:
Mflv_5005|M.gilvum_PYR-GCK VLKLSADRAAGAHPYLTT-PEHTARARELIGPEAFLAPEHKVVLTTDERS
Mvan_1368|M.vanbaalenii_PYR-1 VLQLSATRAAGAHPYLTT-PEHTARARELIGPEALLAPEHKVVLTTDAK-
MSMEG_1514|M.smegmatis_MC2_155 VLQLSAEHSAGAHPYLTT-PEHTRSAREIIGPDAFLAPEHKVVLTTDAE-
MMAR_1084|M.marinum_M VLRLAARRSAGAHPYLTT-PEHTAAARELIGPSAFLAPEHKVVLTTDAQ-
MUL_0842|M.ulcerans_Agy99 VLRLAARRSAGAHPYLTT-PEHTGAARELIGPSAFLAPEHKVVLTTDAQ-
MAV_4404|M.avium_104 VLRLSAERSAGAHPYLTT-PEHTARARELIGPSAFLAPEHKVVLTTDAE-
Mb3492|M.bovis_AF2122/97 VLGLSARRSAGAHPYLTT-PEHTARARELIGPSAFLAPEHKVVLTTDSA-
Rv3463|M.tuberculosis_H37Rv VLGLSARRSAGAHPYLTT-PEHTARARELIGPSAFLAPEHKVVLTTDSA-
MAB_3778|M.abscessus_ATCC_1997 VLKLSADRTAGAHPYLTT-PEHTRQAREIIGPDALLVPEHKVVLSTDAP-
TH_0027|M.thermoresistible__bu MLQLAAQRSAGAHPYLTT-PQHTGQARNRIGPSVFLAPEHKVVLDTDAA-
MLBr_00131|M.leprae_Br4923 MLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPAAV-
:* :. : . * : . * . * : : . . . .. : : .
Mflv_5005|M.gilvum_PYR-GCK REEHVTDPDRAREVGRKALEIYLDLANYLNSWKRLGFSDEDVAKPGSDR-
Mvan_1368|M.vanbaalenii_PYR-1 ---------QAREVGRKALDIYLNLANYLNNWKRLGFGDQDVAKPGSDR-
MSMEG_1514|M.smegmatis_MC2_155 ---------QARAVGRKALDLYLGLANYLNNFKRLGFTDDELAKPGADR-
MMAR_1084|M.marinum_M ---------RARAVGRKALDIYLNLANYLNSWKRLGFCERDIARPGSDR-
MUL_0842|M.ulcerans_Agy99 ---------RARAVGRKALDIYLNLANYLNSWKRLGFSERDIARPGSDR-
MAV_4404|M.avium_104 ---------HARAVGRKALDIYFNLANYRNNWKRLGFTDDEITRPGSDR-
Mb3492|M.bovis_AF2122/97 ---------RARTVGRQALDMYFNLANYRNNWKRLGFTDDEVSRPGSDR-
Rv3463|M.tuberculosis_H37Rv ---------RARTVGRQALDMYFNLANYRNNWKRLGFTDDEVSRPGSDR-
MAB_3778|M.abscessus_ATCC_1997 ---------SAREIGRRTVDFYLTLSNYVNNWKRLGFNDEDLTSPGSDA-
TH_0027|M.thermoresistible__bu ---------AAREIGRQTIGFYLRLRNYVNNWKQLGFTDDDIAEPGSDE-
MLBr_00131|M.leprae_Br4923 ---------RGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHP
. ** . * . **. : * :
Mflv_5005|M.gilvum_PYR-GCK -------------------------------LVDAVVAYGTAEQIAARLR
Mvan_1368|M.vanbaalenii_PYR-1 -------------------------------LVDAVVAYGTVDAIAARLT
MSMEG_1514|M.smegmatis_MC2_155 -------------------------------FIDAVVAYGTVDAIAARLS
MMAR_1084|M.marinum_M -------------------------------LVDAVVAYGTPAAIAARLN
MUL_0842|M.ulcerans_Agy99 -------------------------------LVDAVVAYGTPAAIAARLN
MAV_4404|M.avium_104 -------------------------------LVDALVAYGSVDRIAARLR
Mb3492|M.bovis_AF2122/97 -------------------------------LVDAVVAYGTPDAIAARLN
Rv3463|M.tuberculosis_H37Rv -------------------------------LVDAVVAYGTPDAIAARLN
MAB_3778|M.abscessus_ATCC_1997 -------------------------------FIDAVVAHGTAAEIATRLN
TH_0027|M.thermoresistible__bu -------------------------------LIDAMVAHGTAEQVADALR
MLBr_00131|M.leprae_Br4923 MGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVA
::. :: *: : :
Mflv_5005|M.gilvum_PYR-GCK EHLDAGADHVPVQ----VLTGSDKLVPALA--------------------
Mvan_1368|M.vanbaalenii_PYR-1 EHLDAGADHVPVQ----VLTGSEKLVPALA--------------------
MSMEG_1514|M.smegmatis_MC2_155 EHLAAGADHVPVQ----VLTSPDKLVPALA--------------------
MMAR_1084|M.marinum_M EHLQAGADHVPVQ----VLTKSENLVPALA--------------------
MUL_0842|M.ulcerans_Agy99 EHLQAGADHVPVQ----VLTKSENLVPALA--------------------
MAV_4404|M.avium_104 EHLDAGADHVPVQ----VLTKDENLVSALA--------------------
Mb3492|M.bovis_AF2122/97 EHLLAGADHVPIQ----VLTEDDNLVSALT--------------------
Rv3463|M.tuberculosis_H37Rv EHLLAGADHVPIQ----VLTEDDNLVSALT--------------------
MAB_3778|M.abscessus_ATCC_1997 EHLDAGADQVLIQ----VLG-DKGLVDTLT--------------------
TH_0027|M.thermoresistible__bu EHLDRGADHVAIQ----VLGGRERLLPTLXXSPRCGPNWGRCTSWSRARV
MLBr_00131|M.leprae_Br4923 EWRDHGLKYLVVINGSLVNSSLRKTVSALLP-------------------
* * . : : * : :*
Mflv_5005|M.gilvum_PYR-GCK --------ELAGPLGLESTEEQR
Mvan_1368|M.vanbaalenii_PYR-1 --------ELAGPLGLQRKG---
MSMEG_1514|M.smegmatis_MC2_155 --------ELAGPLGLA------
MMAR_1084|M.marinum_M --------ELAGPLGLTGA----
MUL_0842|M.ulcerans_Agy99 --------ELAGPLGLAGA----
MAV_4404|M.avium_104 --------ELAGPLGLKPS----
Mb3492|M.bovis_AF2122/97 --------ELAKPLRLT------
Rv3463|M.tuberculosis_H37Rv --------ELAKPLRLT------
MAB_3778|M.abscessus_ATCC_1997 --------SLADALR--------
TH_0027|M.thermoresistible__bu WWTSPRSPRSAGRPGSGSSM---
MLBr_00131|M.leprae_Br4923 --------HARVLRGLKKL----