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MSVDVGSVDEIPVGEGRTFAVEDTQVAVFRLRDGSLRAVDAVCPHRGGPLADGLADDCVVVCPLHGHTFD MSTGSEVTGADLSVRSYPVDAVDGTIRLTL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3495 | - | - | 100% (100) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4166 | - | 6e-10 | 31.82% (110) | Rieske (2Fe-2S) domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1329 | - | 3e-06 | 30.53% (95) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 3e-05 | 37.74% (53) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3012 | - | 9e-42 | 80.43% (92) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3526 | - | 3e-05 | 37.74% (53) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4369c | - | 1e-09 | 35.29% (102) | putative ferredoxin subunit of phenylpropionate dioxygenase |
| M. marinum M | MMAR_4726 | - | 1e-09 | 32.08% (106) | hypothetical protein MMAR_4726 |
| M. avium 104 | MAV_0928 | - | 2e-09 | 30.91% (110) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5593 | - | 3e-12 | 38.04% (92) | pyruvate dehydrogenase |
| M. thermoresistible (build 8) | TH_0525 | - | 2e-10 | 30.97% (113) | Rieske |
| M. ulcerans Agy99 | MUL_3820 | - | 3e-05 | 34.33% (67) | ring-hydroxylating dioxygenase, large terminal subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M ----------------------------MGEKTTR----------PRLAQ
MAV_0928|M.avium_104 -----------------------MASETEGAQTKRPE--------PRLAQ
TH_0525|M.thermoresistible__bu ----------------MTAEQRSAPQQNTPRESTRQSPGQNGSQPKRLAQ
MSMEG_5593|M.smegmatis_MC2_155 ----------------------------MTVEEAG-------------QE
Mb3556|M.bovis_AF2122/97 ---------------------------MSTDTSGVGVREIDAGALPTRYA
Rv3526|M.tuberculosis_H37Rv ---------------------------MSTDTSGVGVREIDAGALPTRYA
MAB_4369c|M.abscessus_ATCC_199 -------------------------------------------------M
MUL_3820|M.ulcerans_Agy99 MDRDQLIDLTRRALKLARDKTTDLAPHQHAVDAREYTSLDRHERDRAMVL
Mvan_3495|M.vanbaalenii_PYR-1 -MSVDVGSVDEIPVGE----GRTFAVEDTQVAVFRLRDGSLRAVDAVCPH
Mflv_3012|M.gilvum_PYR-GCK -MKS-----EEIPVGE----GRTLAIDGAQVAVFRLRDGSLRAVDAVCPH
MMAR_4726|M.marinum_M GREHIVATVDEIPPGT----HKLVPIGRHGVGVYNVN-GTFYAIANYCPH
MAV_0928|M.avium_104 GREHVVATVDEIPPGT----HKLVPIGRHGVGVYNVN-GTFYAIANYCPH
TH_0525|M.thermoresistible__bu GREHVVAKVDEIPPGT----HKLVPIGRHGVGVYNVN-GTFYAIANYCPH
MSMEG_5593|M.smegmatis_MC2_155 LEWHRVADHDELDEGQ----VSACPAGRKTVALTKLN-GRYGAIDNRCPH
Mb3556|M.bovis_AF2122/97 RGWHCLGVAKDYLEGK----PHGVEAFGTKLVVFADSHGDLKVLDGYCRH
Rv3526|M.tuberculosis_H37Rv RGWHCLGVAKDYLEGK----PHGVEAFGTKLVVFADSHGDLKVLDGYCRH
MAB_4369c|M.abscessus_ATCC_199 SSGIRVAALEDIPEGEGIVVAKAIAGTADNVALLRDADGSVWALDDTCTH
MUL_3820|M.ulcerans_Agy99 DSPQLVGYSSELPGPD---TYRTKTIMGRSILLTRAADRAVRAFDNVCLH
.: : : .. * *
Mvan_3495|M.vanbaalenii_PYR-1 RGGPLADGLADDC-------------------------------------
Mflv_3012|M.gilvum_PYR-GCK RGGPLADGLADDC-------------------------------------
MMAR_4726|M.marinum_M QGGPLCSGRARGR------------TMVDESAPGD-------AVMVRD--
MAV_0928|M.avium_104 QGGPLCSGRPRGR------------TIVDETAPGD-------SVMVRD--
TH_0525|M.thermoresistible__bu EGGPLCSGRPRGR------------TIVDDSVPGN-------AVMVRD--
MSMEG_5593|M.smegmatis_MC2_155 QGGPLGQGTLENDKIRCPWHGFDFDPFTGEAAGGPDFNVTTYPVDVRDDG
Mb3556|M.bovis_AF2122/97 MGGDLSEGTVKGD-------------------------------------
Rv3526|M.tuberculosis_H37Rv MGGDLSEGTVKGD-------------------------------------
MAB_4369c|M.abscessus_ATCC_199 ADASLAEGWVEDG-------------------------------------
MUL_3820|M.ulcerans_Agy99 RQSRVATGCGTALR------------------------------------
. : *
Mvan_3495|M.vanbaalenii_PYR-1 -----------------------------VVVCPLHGHTFD------MST
Mflv_3012|M.gilvum_PYR-GCK -----------------------------VIVCPLHGHTFD------LSS
MMAR_4726|M.marinum_M ---------------------------LEFIYCPWHQWGFE------LAT
MAV_0928|M.avium_104 ---------------------------LEYIYCPWHQWGFE------LAT
TH_0525|M.thermoresistible__bu ---------------------------MEFIYCPWHQWGFE------LAT
MSMEG_5593|M.smegmatis_MC2_155 IYVGAPPPAPAARTVSDVLVETMTNWGVDTVFGMVGHSNLG------LAE
Mb3556|M.bovis_AF2122/97 -----------------------------EVACPFHDWRWGGDGRCKLVP
Rv3526|M.tuberculosis_H37Rv -----------------------------EVACPFHDWRWGGDGRCKLVP
MAB_4369c|M.abscessus_ATCC_199 -----------------------------YVECPLHSSKFC-----LKTG
MUL_3820|M.ulcerans_Agy99 ------------------------------FTCPYHGWTYDNGGRLVGLP
.
Mvan_3495|M.vanbaalenii_PYR-1 GSEVTG----ADLSVRSYPVDAVDGTIRLTL-------------------
Mflv_3012|M.gilvum_PYR-GCK GEEVSG----AQMSVRSYPVEEIDGEIRLGLA------------------
MMAR_4726|M.marinum_M GTTAVK----PEWSIRTYPVRVIGRDVLVMA-------------------
MAV_0928|M.avium_104 GTTAVK----PEWSIRTYPVRVVGNDVVVQA-------------------
TH_0525|M.thermoresistible__bu GTTAVK----PEWSIRTYPVRVVGDEVLVTA-------------------
MSMEG_5593|M.smegmatis_MC2_155 AMHRAE----NAGKLRYFGIRHEGAAAFAASAYGKLTGRPAACFGIAGPG
Mb3556|M.bovis_AF2122/97 YARRTP----RMARTRSWTTDVRSGLLFVWHDHEGNP-----------PD
Rv3526|M.tuberculosis_H37Rv YARRTP----RMARTRSWTTDVRSGLLFVWHDHEGNP-----------PD
MAB_4369c|M.abscessus_ATCC_199 AVDGLP----ATKDTCPHRIEVRDGDIFLFPGEKPRPL------------
MUL_3820|M.ulcerans_Agy99 GREGFPGIAVGSDGLTELPATEFAGFLWVSLHPAARLDVPAHLGPLAGEL
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 STNLLTGLYDAKADRAPVLALSGNVESAVAGKGAFQDIDLLAAFADVAVY
Mb3556|M.bovis_AF2122/97 PAVRIPEIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFG
Rv3526|M.tuberculosis_H37Rv PAVRIPEIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFG
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 QSWGIGRWSPLGEKVLGSPIDWKLATDTFAENYHFATVHRRTFAT-----
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 SEMVRDGSEHAELMTMALKHAILERGVAHLVVPDEVQVIQSDRRSSGPEG
Mb3556|M.bovis_AF2122/97 -------------LPTYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAH
Rv3526|M.tuberculosis_H37Rv -------------LPTYFKNVFEGHIASQYLHNVGRPDVDDLGTSYGEAH
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 -------------IARSNCTVFDSYGPHHRLIFPLNTILELENVPEGQWD
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 RMPDLRVAPPSTPLERALDRIAAATRPAVIVGAGAKFDMAAIVALAERLH
Mb3556|M.bovis_AF2122/97 LDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQN----------
Rv3526|M.tuberculosis_H37Rv LDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQN----------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 PFHHMVVIYALFPNVVLSVTIANGELFRIYPGDRP---------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 APVLTTFKAKGQIADDHPLACGALGRSGTPVASWMMNKADLLVVFGASFS
Mb3556|M.bovis_AF2122/97 ---------------SFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKG
Rv3526|M.tuberculosis_H37Rv ---------------SFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKG
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 ---------------------------------------------GSSIT
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 NHTGISPYKPVIQVDTDPLVLGRFNPVAVPVLGDVGVTASALTQRLRTHP
Mb3556|M.bovis_AF2122/97 FLQDVEIWKHKTRIDNPLLVE------------EDGAVYQLRRWYEQFYV
Rv3526|M.tuberculosis_H37Rv FLQDVEIWKHKTRIDNPLLVE------------EDGAVYQLRRWYEQFYV
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 VHQNSTPLDLS----------------------DESVATGAQAVFDYAHA
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 DLVDQRAEIAERWSVWRTEKARRATKQPGGRIAAATVFDELGRLVPAGAV
Mb3556|M.bovis_AF2122/97 DVADIKPEMVERFEIEVDTKR--ANEFWNAEVEKNLKSREVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv DVADIKPEMVERFEIEVDTKR--ANEFWNAEVEKNLKSREVSDDVPAEQH
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 TVRDEDYRLAETLQTNLESGARQRLVFGRNEPGLQHRHITWAQALETPG-
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 LTVDVGNHAYSFGRYFETKDEQTVLMSGYLGSIGFGFPAAMGAWAAAPDR
Mb3556|M.bovis_AF2122/97 --------------------------------------------------
Rv3526|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 PIVAVTGDGGFGQYLADFTTAVKYGMNITHILLNNGELGKITQEQRSSEY
Mb3556|M.bovis_AF2122/97 --------------------------------------------------
Rv3526|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MAV_0928|M.avium_104 --------------------------------------------------
TH_0525|M.thermoresistible__bu --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 EVWQTSLLNPDFAAYARDCGAYGNQVISHTELGTVIAEALAHPGPALVEI
Mb3556|M.bovis_AF2122/97 --------------------------------------------------
Rv3526|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 -------
Mflv_3012|M.gilvum_PYR-GCK -------
MMAR_4726|M.marinum_M -------
MAV_0928|M.avium_104 -------
TH_0525|M.thermoresistible__bu -------
MSMEG_5593|M.smegmatis_MC2_155 ITDAWSN
Mb3556|M.bovis_AF2122/97 -------
Rv3526|M.tuberculosis_H37Rv -------
MAB_4369c|M.abscessus_ATCC_199 -------
MUL_3820|M.ulcerans_Agy99 -------