For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KSEEIPVGEGRTLAIDGAQVAVFRLRDGSLRAVDAVCPHRGGPLADGLADDCVIVCPLHGHTFDLSSGEE VSGAQMSVRSYPVEEIDGEIRLGLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3012 | - | - | 100% (96) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2488 | - | 2e-08 | 29.25% (106) | Rieske (2Fe-2S) domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4333 | - | 3e-07 | 33.33% (93) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0259 | nirD | 2e-05 | 36.11% (72) | nitrite reductase |
| M. tuberculosis H37Rv | Rv0253 | nirD | 2e-05 | 36.11% (72) | nitrite reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4369c | - | 2e-09 | 37.50% (96) | putative ferredoxin subunit of phenylpropionate dioxygenase |
| M. marinum M | MMAR_4726 | - | 2e-08 | 31.13% (106) | hypothetical protein MMAR_4726 |
| M. avium 104 | MAV_3508 | - | 1e-09 | 33.72% (86) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5593 | - | 3e-11 | 36.26% (91) | pyruvate dehydrogenase |
| M. thermoresistible (build 8) | TH_4003 | - | 9e-10 | 38.64% (88) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3820 | - | 5e-06 | 37.50% (64) | ring-hydroxylating dioxygenase, large terminal subunit |
| M. vanbaalenii PYR-1 | Mvan_3495 | - | 1e-41 | 80.43% (92) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3012|M.gilvum_PYR-GCK -------------MKS------------------EEIPVGEG---RTLAI
Mvan_3495|M.vanbaalenii_PYR-1 -------------MSVDVG-------------SVDEIPVGEG---RTFAV
MMAR_4726|M.marinum_M -------------MGEKTTRPRLAQGREHIVATVDEIPPGTH---KLVPI
MSMEG_5593|M.smegmatis_MC2_155 -------------MTVEEAGQELEWHR---VADHDELDEGQV---SACPA
Mb0259|M.bovis_AF2122/97 -------------MTLLNDIQVWTT-----ACAYDHLIPGRG---VGVLL
Rv0253|M.tuberculosis_H37Rv -------------MTLLNDIQVWTT-----ACAYDHLIPGRG---VGVLL
MAB_4369c|M.abscessus_ATCC_199 -------------MSSG-----------IRVAALEDIPEGEGIVVAKAIA
TH_4003|M.thermoresistible__bu -------------MSGEHTDTLRW----VRAACLDDVPGDE----PLGLV
MAV_3508|M.avium_104 -------------MVGRPRAGRLQKVG---SKVVAAIGRQEWMDRPSYRF
MUL_3820|M.ulcerans_Agy99 MDRDQLIDLTRRALKLARDKTTDLAPHQHAVDAREYTSLDRHERDRAMVL
:
Mflv_3012|M.gilvum_PYR-GCK DG-----------------------AQVAVFRLRDGSLRAVDAVCPHRGG
Mvan_3495|M.vanbaalenii_PYR-1 ED-----------------------TQVAVFRLRDGSLRAVDAVCPHRGG
MMAR_4726|M.marinum_M GR-----------------------HGVGVYNVN-GTFYAIANYCPHQGG
MSMEG_5593|M.smegmatis_MC2_155 GR-----------------------KTVALTKLN-GRYGAIDNRCPHQGG
Mb0259|M.bovis_AF2122/97 DDG----------------------SQVALFRLDDGSVHAVGNVDPFSGA
Rv0253|M.tuberculosis_H37Rv DDG----------------------SQVALFRLDDGSVHAVGNVDPFSGA
MAB_4369c|M.abscessus_ATCC_199 GTA----------------------DNVALLRDADGSVWALDDTCTHADA
TH_4003|M.thermoresistible__bu VDG----------------------IEIALFND-DGRIFALADRCTHGDA
MAV_3508|M.avium_104 EHL----------------------LSFAYNGLGSARNTVTNALNGVWLG
MUL_3820|M.ulcerans_Agy99 DSPQLVGYSSELPGPDTYRTKTIMGRSILLTRAADRAVRAFDNVCLHRQS
. . .
Mflv_3012|M.gilvum_PYR-GCK PLADGLADD-----------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 PLADGLADD-----------------------------------------
MMAR_4726|M.marinum_M PLCSGRARG------------RTMVDESAPG-------------------
MSMEG_5593|M.smegmatis_MC2_155 PLGQGTLENDKIRCPWHGFDFDPFTGEAAGGPDFNVTTYPVDVRDDGIYV
Mb0259|M.bovis_AF2122/97 AVMSRGIVG-----------------------------------------
Rv0253|M.tuberculosis_H37Rv AVMSRGIVG-----------------------------------------
MAB_4369c|M.abscessus_ATCC_199 SLAEGWVED-----------------------------------------
TH_4003|M.thermoresistible__bu RLSDGYIED-----------------------------------------
MAV_3508|M.avium_104 HPVHPPLAS-----------------------------------------
MUL_3820|M.ulcerans_Agy99 RVATGCGTA-----------------------------------------
Mflv_3012|M.gilvum_PYR-GCK -------------------------CVIVCPLHGHTFDLS---------S
Mvan_3495|M.vanbaalenii_PYR-1 -------------------------CVVVCPLHGHTFDMS---------T
MMAR_4726|M.marinum_M -----------------DAVMVRDLEFIYCPWHQWGFELA---------T
MSMEG_5593|M.smegmatis_MC2_155 GAPPPAPAARTVSDVLVETMTNWGVDTVFGMVGHSNLGLA---------E
Mb0259|M.bovis_AF2122/97 --------------------DRGGRAMVQSPILKQAFALD---------D
Rv0253|M.tuberculosis_H37Rv --------------------DRGGRAMVQSPILKQAFALD---------D
MAB_4369c|M.abscessus_ATCC_199 -------------------------GYVECPLHSSKFCLK---------T
TH_4003|M.thermoresistible__bu -------------------------GCIECPLHQALFDLA---------T
MAV_3508|M.avium_104 ----------------------LTSGALGTTVALDALSVL---------P
MUL_3820|M.ulcerans_Agy99 -------------------------LRFTCPYHGWTYDNGGRLVGLPGRE
.
Mflv_3012|M.gilvum_PYR-GCK GEEVSGAQMS-VRSYPVEEIDGEIRLGLA---------------------
Mvan_3495|M.vanbaalenii_PYR-1 GSEVTGADLS-VRSYPVDAVDGTIRLTL----------------------
MMAR_4726|M.marinum_M GTTAVKPEWS-IRTYPVRVIGRDVLVMA----------------------
MSMEG_5593|M.smegmatis_MC2_155 AMHRAENAGK-LRYFGIRHEGAAAFAASAYGKLTGRPAACFGIAGPGSTN
Mb0259|M.bovis_AF2122/97 GSCLDDPRVS-VPVYPARVTPEGRIQVARVAV------------------
Rv0253|M.tuberculosis_H37Rv GSCLDDPRVS-VPVYPARVTPEGRIQVARVAV------------------
MAB_4369c|M.abscessus_ATCC_199 GAVDGLPATKDTCPHRIEVRDGDIFLFPGEKPRPL---------------
TH_4003|M.thermoresistible__bu GEVRRGPAFEPVRSFEIRIDGDDIIVGL----------------------
MAV_3508|M.avium_104 GQ--PASEVVDASRFATRALGVGILASLGSAVTGVTDWQHTHEEDRRVG-
MUL_3820|M.ulcerans_Agy99 GFPGIAVGSDGLTELPATEFAGFLWVSLHPAARLDVPAHLGPLAGELQSW
.
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 LLTGLYDAKADRAPVLALSGNVESAVAGKGAFQDIDLLAAFADVAVYSEM
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 AVHGLLNVAATALYVQSWFDRRRGRHGRGILLTALGYGITVAGSYLGGAL
MUL_3820|M.ulcerans_Agy99 GIGRWSPLGEKVLGSPIDWKLATDTFAENYHFATVHRRTFATIARSNCTV
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 VRDGSEHAELMTMALKHAILERGVAHLVVPDEVQVIQSDRRSSGPEGRMP
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 VFESGIGIDQSGPRLRTSAWTPVLPASSLNGKPVRVEVDGVGLVVCQTKP
MUL_3820|M.ulcerans_Agy99 FDSYGPHHRLIFPLNTILELENVPEGQWDPFHHMVVIYALFPNVVLSVTI
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 DLRVAPPSTPLERALDRIAAATRPAVIVGAGAKFDMAAIVALAERLHAPV
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 GEVAAYGEFCPHLAAPMADGWLDRGRLVCPWHGSWFAAESGEVVRGPAAA
MUL_3820|M.ulcerans_Agy99 ANGELFRIYPGDRPGSSITVHQNSTPLDLSDESVATGAQAVFDYAHATVR
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 LTTFKAKGQIADDHPLACGALGRSGTPVASWMMNKADLLVVFGASFSNHT
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 PLPCYQARVVDGVVEVRGEQQPAPGGAVGIAKGGAS--------------
MUL_3820|M.ulcerans_Agy99 DEDYRLAETLQTNLESGARQRLVFGRNEPGLQHRHITWAQALETPG----
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 GISPYKPVIQVDTDPLVLGRFNPVAVPVLGDVGVTASALTQRLRTHPDLV
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 DQRAEIAERWSVWRTEKARRATKQPGGRIAAATVFDELGRLVPAGAVLTV
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 DVGNHAYSFGRYFETKDEQTVLMSGYLGSIGFGFPAAMGAWAAAPDRPIV
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 AVTGDGGFGQYLADFTTAVKYGMNITHILLNNGELGKITQEQRSSEYEVW
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3495|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4726|M.marinum_M --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155 QTSLLNPDFAAYARDCGAYGNQVISHTELGTVIAEALAHPGPALVEIITD
Mb0259|M.bovis_AF2122/97 --------------------------------------------------
Rv0253|M.tuberculosis_H37Rv --------------------------------------------------
MAB_4369c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4003|M.thermoresistible__bu --------------------------------------------------
MAV_3508|M.avium_104 --------------------------------------------------
MUL_3820|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3012|M.gilvum_PYR-GCK ----
Mvan_3495|M.vanbaalenii_PYR-1 ----
MMAR_4726|M.marinum_M ----
MSMEG_5593|M.smegmatis_MC2_155 AWSN
Mb0259|M.bovis_AF2122/97 ----
Rv0253|M.tuberculosis_H37Rv ----
MAB_4369c|M.abscessus_ATCC_199 ----
TH_4003|M.thermoresistible__bu ----
MAV_3508|M.avium_104 ----
MUL_3820|M.ulcerans_Agy99 ----