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GISKVERLMNLVIALLSTRSFITADRIRETVFGYSDDASDEAFSRMFERDKNELRDLGIPLETGRVSPSD PAEGYRINRESYALPAVELTPDEAAAVAVATQLWESPELITATQSALLKLRAAGIDIEAADDDIAITSTA ALPGLRGSEEVLGILLSAIDSGRAVRFRHRPSRSEPYMTRTVEPWGVVTDRGRWYLVGHDRDRDAVRTFR LSRIGADVTPIGDAGSVSRPDGIDLREIVKRVVGDWPATGQARVWVAEGRATALRRRGTVVGPKMVGGRA GDEITVDIGMFDRLAREVASYGADALALEPQSLRDDVIARLRAQLSTVSEVEAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3444 | - | - | 100% (335) | hypothetical protein Mvan_3444 |
| M. vanbaalenii PYR-1 | Mvan_1247 | - | 4e-09 | 28.44% (218) | helix-turn-helix, type 11 domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2933 | - | 4e-06 | 27.05% (329) | helix-turn-helix, type 11 domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2123c | - | 1e-129 | 70.82% (329) | hypothetical protein Mb2123c |
| M. gilvum PYR-GCK | Mflv_3091 | - | 1e-157 | 84.19% (329) | hypothetical protein Mflv_3091 |
| M. tuberculosis H37Rv | Rv2096c | - | 1e-129 | 70.82% (329) | hypothetical protein Rv2096c |
| M. leprae Br4923 | MLBr_01329 | - | 1e-120 | 66.15% (325) | hypothetical protein MLBr_01329 |
| M. abscessus ATCC 19977 | MAB_2185 | - | 1e-126 | 67.69% (325) | hypothetical protein MAB_2185 |
| M. marinum M | MMAR_3082 | - | 1e-128 | 69.49% (331) | hypothetical protein MMAR_3082 |
| M. avium 104 | MAV_2407 | - | 1e-134 | 74.54% (326) | hypothetical protein MAV_2407 |
| M. smegmatis MC2 155 | MSMEG_1359 | - | 4e-11 | 26.65% (319) | DeoR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3928 | - | 2e-17 | 56.00% (75) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2328 | - | 1e-128 | 69.49% (331) | hypothetical protein MUL_2328 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3444|M.vanbaalenii_PYR-1 ---------------------MGISKVERLMNLVIALLSTRSFITADRIR
Mflv_3091|M.gilvum_PYR-GCK MCPDAHIACRKGFLARLKLIAVAISKVERLMNLVIALLSTRSFITADRIR
Mb2123c|M.bovis_AF2122/97 ---------------------MATSKVERLVNLVIALLSTRGYITAEKIR
Rv2096c|M.tuberculosis_H37Rv ---------------------MATSKVERLVNLVIALLSTRGYITAEKIR
MAV_2407|M.avium_104 -------------------MPMATSKVERLVNLVIALLSTRGYITAEKIR
MLBr_01329|M.leprae_Br4923 ---------------------MATSKVERLVNLVIALLSTRGYMTAEKIR
MMAR_3082|M.marinum_M ---------------------MATSKVERMVNLVIALLSTRGYITAEKVR
MUL_2328|M.ulcerans_Agy99 ---------------------MATSKVERMVNLVIALLSTRGYITAEKVR
MAB_2185|M.abscessus_ATCC_1997 ---------------------MAISKVERLMNLVICLLSTRTYVTAERIR
TH_3928|M.thermoresistible__bu --------------------------------------------------
MSMEG_1359|M.smegmatis_MC2_155 --------------------MARTVDTTGRVVQLLGLLQSRRVWTGEELA
Mvan_3444|M.vanbaalenii_PYR-1 ETVFGYSDDASDEAFSRMFERDKNELRDLGIPLETGRVSPSDPAEGYRIN
Mflv_3091|M.gilvum_PYR-GCK ETVYGYSGAASDEAFSRMFERDKNELRDLGIPLETGRASSSDPAEGYRIN
Mb2123c|M.bovis_AF2122/97 SSVAGYSDSPSVEAFSRMFERDKNELRDLGIPLEVGRVSALEPTEGYRIN
Rv2096c|M.tuberculosis_H37Rv SSVAGYSDSPSVEAFSRMFERDKNELRDLGIPLEVGRVSALEPTEGYRIN
MAV_2407|M.avium_104 SSVAGYSESASAEAFSRMFERDKNELRDLGIPLEVGRVSPMDPTEGYRIN
MLBr_01329|M.leprae_Br4923 SSVAGYSDSPTVEAFSRMFERDKNELRDLGIPLEVGKVSALDPSEGYRIN
MMAR_3082|M.marinum_M SSVAGYSDSPTAEAFSRMFERDKNELRDLGIPLEVGRVSSTDPTEGYRIN
MUL_2328|M.ulcerans_Agy99 SSVAGYSDSPTAEAFSRMFERDKNELRDLGIPLEVGRVSSTDPTEGYRIN
MAB_2185|M.abscessus_ATCC_1997 TSVAGYSDSPSDEAFSRMFERDKNELRDLGIPLETGKVSSFDATEGYRIR
TH_3928|M.thermoresistible__bu --------------------------------------------------
MSMEG_1359|M.smegmatis_MC2_155 ERLG---------VTGRSVRRDIERLRELGYPVHASKGQG----GGYQLG
Mvan_3444|M.vanbaalenii_PYR-1 RESYALPAVELTPDEAAAVAVATQLWESPELITATQSALLKLRAAGIDIE
Mflv_3091|M.gilvum_PYR-GCK REAYALPAVELTPDEAAAVAVATQLWQSPELITATQGALLKLRAAGIEVE
Mb2123c|M.bovis_AF2122/97 RDAYALSPVELTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVD
Rv2096c|M.tuberculosis_H37Rv RDAYALSPVELTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVD
MAV_2407|M.avium_104 RDAYALAPVDLTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVD
MLBr_01329|M.leprae_Br4923 RDAYALPPVELTPDEAAAVAVATQLWESQELITATQGALLKLRAAGVDID
MMAR_3082|M.marinum_M RDAYALPPVELTPDETAAVAVATQLWESPELITATQGALLKLRAAGVDVD
MUL_2328|M.ulcerans_Agy99 RDAYALPPVELTPDETAAVAVATQLWESPELITATQGALLKLRAAGVDVD
MAB_2185|M.abscessus_ATCC_1997 RDAYELPDITLTADESAAVAVATQLWQSPELVTAAQGALMKLRAAGVDVD
TH_3928|M.thermoresistible__bu --------------------------------------------------
MSMEG_1359|M.smegmatis_MC2_155 -AGMALPPLLLDPDEAVAMAVCLRLAAGGSVAGVGESALRALSKLDQVMP
Mvan_3444|M.vanbaalenii_PYR-1 A--ADDDIAITSTAALPGLRGSE-----EVLGILLSAIDSGRAVRFRHRP
Mflv_3091|M.gilvum_PYR-GCK A--PDGDVAITSTAALPGLRGSE-----EVLGILLSAIDSGRAVTFSYRP
Mb2123c|M.bovis_AF2122/97 PLDTGAPVAIASAAAVSGLRGSE-----DVLGILLSAIDSGQVVQFSHRS
Rv2096c|M.tuberculosis_H37Rv PLDTGAPVAIASAAAVSGLRGSE-----DVLGILLSAIDSGQVVQFSHRS
MAV_2407|M.avium_104 PLDDGAPVAIASPAGVPGLRGSE-----EVLGILLSAIDSRQAVQFPHRP
MLBr_01329|M.leprae_Br4923 PLDT--PVVIASSSGVSSLRGSE-----DFLSILLSAIGSRQAVQFPYRP
MMAR_3082|M.marinum_M ---PDAPVAIASPAGVPGLRGSE-----DVLGILLAAIDSGQAVRFPHRA
MUL_2328|M.ulcerans_Agy99 ---PDAPVAIASPAGVPGLRGSE-----DVLGILLAAIDSGQAVRFPHRA
MAB_2185|M.abscessus_ATCC_1997 P--AAENVSVAAPAAMPGGRGSE-----SVLRILLSAIDSGQAVQFGHRP
TH_3928|M.thermoresistible__bu --------------------------------------------------
MSMEG_1359|M.smegmatis_MC2_155 ARLRSQVAAIHDATVTLGPNATDTAVAPDVLMTLARACRDREHVSTGYTD
Mvan_3444|M.vanbaalenii_PYR-1 SRSEPYMTRTVEPWGVVTDRGRWYLVGHDRDRDAVRTFRLSRIGADVTPI
Mflv_3091|M.gilvum_PYR-GCK ARSEPYVTRTLEPWGVVTDRGRWYVVGHDRDRDDVRTFRLSRIGADVMPT
Mb2123c|M.bovis_AF2122/97 SRAEPYTVRTVEPWGVVTEKGRWYLVGHDRDRDATRVFRLSRIGAQVTPI
Rv2096c|M.tuberculosis_H37Rv SRAEPYTVRTVEPWGVVTEKGRWYLVGHDRDRDATRVFRLSRIGAQVTPI
MAV_2407|M.avium_104 SRAEPYATRTVEPWGVVTQKGRWYLVGHDRDRDATRTFRLSRIGPGVTPI
MLBr_01329|M.leprae_Br4923 SRAEPYTMRNVEPWGVITENSCWYLVGHDCDRNATRTFRLSRIGSEVAPI
MMAR_3082|M.marinum_M SRHEPYVTRTVEPWGVVTEKGRWYLVGHDRDRGATRTFRLSRIGADVAPV
MUL_2328|M.ulcerans_Agy99 SRHEPYVTRTVEPWGVVTEKGRWYLVGHDRDRGATRTFRLSRIGADVAPV
MAB_2185|M.abscessus_ATCC_1997 SRTEPYVTRTVEPWGVITDRGRWYLVGHDRDRDATRTFRLSRIGEDVTKI
TH_3928|M.thermoresistible__bu --------------------------------------------------
MSMEG_1359|M.smegmatis_MC2_155 LRGN-QTQRRLEPYQLVTTGRRWYLMAYDRDREDWRSLRLDRMS-DVRAT
Mvan_3444|M.vanbaalenii_PYR-1 GDAGSVSRPDGIDLREIVKRVVGDW---PATGQARVWVAEGRATALRRRG
Mflv_3091|M.gilvum_PYR-GCK GPTGVVRKPDGVDLRAIVARVVGEW---PAAGKATVWVADGRATALRRQG
Mb2123c|M.bovis_AF2122/97 GPAGATTVPAGVDLRSIVAQKVTEV---PTGEQATVWVAEGRATALRRAG
Rv2096c|M.tuberculosis_H37Rv GPAGATTVPAGVDLRSIVAQKVTEV---PTGEQATVWVAEGRATALRRAG
MAV_2407|M.avium_104 GPPGAVTVPDGVDLRRIVAQTVTDVSATPAGGQARVWVADGRATALRRAG
MLBr_01329|M.leprae_Br4923 GPAGAVTVPDGVDLRRIVSDAVAEV---STGATARVWVVDGRATALRHAG
MMAR_3082|M.marinum_M GAPGEAEVPEDVDLRQIVARTVAES---PTGMQATVWVADGRATALRRAG
MUL_2328|M.ulcerans_Agy99 GAPGESKIPEDVDLRQIVARTVAES---PTGMQATVWVADGRATALRRAG
MAB_2185|M.abscessus_ATCC_1997 EKPGTIRRPEGADLRAIVAAAVGDG---PVRITARVWIAEGRAQELRRMG
TH_3928|M.thermoresistible__bu -------------------------------------VADGRAMTLRRQA
MSMEG_1359|M.smegmatis_MC2_155 G--TTFTARPAPDAAAYVGRAISAS---AYPYVARVRYFAPEKVVAQRFP
. ::
Mvan_3444|M.vanbaalenii_PYR-1 TVVGPKMVGGRAGDEITVDIGMFDRLAREVASYGADALALEPQSLRDDVI
Mflv_3091|M.gilvum_PYR-GCK TVLGPRTVGGRSGEEISVDIGMFDRLAREVAGYGADALVLEPESLREDVI
Mb2123c|M.bovis_AF2122/97 RSAGPRQLGGRDGEVIELEIRSSDRLAREITGYGADAIVLQPGSLRDDVL
Rv2096c|M.tuberculosis_H37Rv RSAGPRQLGGRDGEVIELEIRSSDRLAREITGYGADAIVLQPGSLRDDVL
MAV_2407|M.avium_104 RPVGTRQLGGRDGEVIELDIRATDQLARDIAGYGADAVVLEPQSLRDDVL
MLBr_01329|M.leprae_Br4923 RPAGVRRLGGRDGQVIELDIGSIDRLARDIAGHGADAVVLEPDALRDDVL
MMAR_3082|M.marinum_M RSMGPRRLAGRDGEVIELEIGSSDRLARDITGHGADAIVLEPPALREDVL
MUL_2328|M.ulcerans_Agy99 PSMGPRRLAGRDGEVIKLEIGSSDRLARDITGHGADAIVLEPPALREDVL
MAB_2185|M.abscessus_ATCC_1997 VVVDSRRLGERDGDIVEIDVASPDRLVRSIASHGADAVALEPAQVRDEVV
TH_3928|M.thermoresistible__bu TAAEPMTLAGRNGQVLTLEVGTGDRMAREIASYGPDAVALEPVSLRADVI
MSMEG_1359|M.smegmatis_MC2_155 PGTATFEPDGPDACIVTSGAEYPEQLAMYFATVGHDFEVLEPAEVIDAVG
. : :::. .: * * .*:* : *
Mvan_3444|M.vanbaalenii_PYR-1 ARLRAQLSTVSEVEAR---------
Mflv_3091|M.gilvum_PYR-GCK ARLEAHLAPVEAGKGADRL------
Mb2123c|M.bovis_AF2122/97 ARLRAQAGALA--------------
Rv2096c|M.tuberculosis_H37Rv ARLRAQAGALA--------------
MAV_2407|M.avium_104 ARLRAHAGADAVGAGRPGGRGGVSA
MLBr_01329|M.leprae_Br4923 IRLRAHAGTGPS-------------
MMAR_3082|M.marinum_M ARLRALAGVEEALA-----------
MUL_2328|M.ulcerans_Agy99 ARLRALAGVEEALA-----------
MAB_2185|M.abscessus_ATCC_1997 ARLQEQAGVTA--------------
TH_3928|M.thermoresistible__bu ERLRAQAGVSEERIAQ---------
MSMEG_1359|M.smegmatis_MC2_155 AMADRLRRAVR--------------