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MWKCGRMRADRLVAILLLLQQRKQVTASEVALELEVSERTARRDLEALSGAGVPVYAMPGRGGGWRLLGG ARTDLSGLTASEARALFLVAGPASTATPSVKAALRKLVRALPEPFREQAEAAATSVVVDPRHWGSSQPEP RPPRFLDELQEAVIRGVQVRLGYVDRKGSQTERTVHPLGIVAKRPTWYLVSNTDAGRRTFRIDRVSSVEL TDDAVQRPQGFDLAESWREIADEVDRKRTPLEAQAMCAADGLGLLRMVLGGRLEVGGSTPDGRIEIVIRG HNEYALAGELAGLIEWLEVTGPQGVRDHLASIGGALVARYS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2933 | - | - | 100% (321) | helix-turn-helix, type 11 domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_1247 | - | 3e-17 | 31.71% (205) | helix-turn-helix, type 11 domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_2934 | - | 4e-15 | 31.16% (215) | helix-turn-helix, type 11 domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_5106 | - | 4e-18 | 32.52% (206) | helix-turn-helix, type 11 domain-containing protein |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2185 | - | 7e-06 | 25.36% (343) | hypothetical protein MAB_2185 |
M. marinum M | - | - | - | - | - |
M. avium 104 | MAV_2407 | - | 3e-06 | 28.14% (334) | hypothetical protein MAV_2407 |
M. smegmatis MC2 155 | MSMEG_1359 | - | 4e-18 | 33.33% (210) | DeoR-family protein transcriptional regulator |
M. thermoresistible (build 8) | TH_1858 | - | 7e-19 | 32.11% (218) | DeoR-family protein transcriptional regulator |
M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_1359|M.smegmatis_MC2_155 ---MARTVDTTGRVVQLLGLLQSRRVWTGEELAERLG---------VTGR TH_1858|M.thermoresistible__bu MWQAADVSETTSRVLRLLGLLQSRRVWSGEELAERLG---------VTTR Mflv_5106|M.gilvum_PYR-GCK ------MSETTGRVLQLLGLLQSRRVWSGDELAARLR---------VTTR MAB_2185|M.abscessus_ATCC_1997 ----MAISKVERLMNLVICLLSTRTYVTAERIRTSVAGYSDSPSDEAFSR MAV_2407|M.avium_104 --MPMATSKVERLVNLVIALLSTRGYITAEKIRSSVAGYSESASAEAFSR Mvan_2933|M.vanbaalenii_PYR-1 --MWKCGRMRADRLVAILLLLQQRKQVTASEVALELE---------VSER : :: **. * :...: : . * MSMEG_1359|M.smegmatis_MC2_155 SVRRDIERLRELGYPVHASKGQ----GGGYQLG--AGMALPPLLLDPDEA TH_1858|M.thermoresistible__bu SVRRDVERLRDLGYPVHASRGH----GGGYQLG--AGAALPPLLLDPEEA Mflv_5106|M.gilvum_PYR-GCK SVRRDIDRLRELGYPVHASTGH----GGGYQLG--AGAALPPLLLDPDEA MAB_2185|M.abscessus_ATCC_1997 MFERDKNELRDLGIPLETGKVSSFDATEGYRIRR-DAYELPDITLTADES MAV_2407|M.avium_104 MFERDKNELRDLGIPLEVGRVSPMDPTEGYRINR-DAYALAPVDLTPDEA Mvan_2933|M.vanbaalenii_PYR-1 TARRDLEALSGAGVPVYAMPGR----GGGWRLLGGARTDLSGLTASEARA .** : * * *: . *::: *. : .: MSMEG_1359|M.smegmatis_MC2_155 VAMAVCLRLAAGGSVAGVGESALRALSKLDQVMPARLRSQVAAIHDATVT TH_1858|M.thermoresistible__bu VAVAVCLRLAAGGSIAGVGESALRALGKLDQVMPARLRSQVSAVHEATTT Mflv_5106|M.gilvum_PYR-GCK VAVAVCLRVAAGGSVAGVGESALRALSKLDQVMPSRLRSQVAAVHDTTVT MAB_2185|M.abscessus_ATCC_1997 AAVAVATQLWQSPELVTAAQGALMKLRAAGVDVDPAAEN--VSVAAPAAM MAV_2407|M.avium_104 AAVAVATQLWESPELITATQGALLKLRAAGVDVDPLDDGAPVAIASPAGV Mvan_2933|M.vanbaalenii_PYR-1 LFLVAGPASTATPSVKAALRKLVRALPEP---FREQAEAAATSVVVDPRH :.. .: . . : * . :: . MSMEG_1359|M.smegmatis_MC2_155 LGPNATDTAVAPDVLMTLARACRDREHVSTGYTDLRGN-QTQRRLEPYQL TH_1858|M.thermoresistible__bu LGPNQPDQPVAPDVLMTLARACRDHEHVNTGYTDRAGN-RSRRRLEPYQL Mflv_5106|M.gilvum_PYR-GCK LAG-ATDTPVEPEVLMTLARASRDHEHVTVGYTDVRGN-VTSRRVEPYQL MAB_2185|M.abscessus_ATCC_1997 PGGRGSES-----VLRILLSAIDSGQAVQFGHRPSRTEPYVTRTVEPWGV MAV_2407|M.avium_104 PGLRGSEE-----VLGILLSAIDSRQAVQFPHRPSRAEPYATRTVEPWGV Mvan_2933|M.vanbaalenii_PYR-1 WGSSQPEPR-PPRFLDELQEAVIRGVQVRLGYVDRKGS-QTERTVHPLGI . .: .* * * * : . * :.* : MSMEG_1359|M.smegmatis_MC2_155 VTTGRRWYLMAYDRDREDWRSLRLDRMS-DVRATG--TTFTARPAPDAAA TH_1858|M.thermoresistible__bu VTTGRRWYLLAYDRDRGDWRSLRLDRMT-DVRALG--STFTPRPAPDAAE Mflv_5106|M.gilvum_PYR-GCK VTTGRRWYLMCFDRDRDDWRSLRLDRMS-DVRAVG--TTFIPREAPDAAS MAB_2185|M.abscessus_ATCC_1997 ITDRGRWYLVGHDRDRDATRTFRLSRIGEDVTKIEKPGTIRRPEGADLRA MAV_2407|M.avium_104 VTQKGRWYLVGHDRDRDATRTFRLSRIGPGVTPIGPPGAVTVPDGVDLRR Mvan_2933|M.vanbaalenii_PYR-1 VAKRPTWYLVSN--TDAGRRTFRIDRVS-SVELTD--DAVQRPQGFDLAE :: ***: *::*:.*: .* :. . * MSMEG_1359|M.smegmatis_MC2_155 YVGRAISAS---AYPYVARVRYFAPEKVVAQRFPPGTATFEPDGPDA-CI TH_1858|M.thermoresistible__bu FVRHSISAS---PYRHVARVRFRAPERVVSQHFPAAAVMIEPDGPDT-CI Mflv_5106|M.gilvum_PYR-GCK YVRRAISSS---PYPYVARVRYRAPADVVARVFPAASVDVEPDGPDA-CI MAB_2185|M.abscessus_ATCC_1997 IVAAAVGDG---PVRITARVWIAEGRAQELRRMGVVVDSRRLGERDG-DI MAV_2407|M.avium_104 IVAQTVTDVSATPAGGQARVWVADGRATALRRAGRPVGTRQLGGRDG-EV Mvan_2933|M.vanbaalenii_PYR-1 SWREIADEVDRKRTPLEAQAMCAADGLGLLRMVLGGRLEVGGSTPDGRIE *:. : . * MSMEG_1359|M.smegmatis_MC2_155 VTSGAEYPEQLAMYFATVGHDFEVLEPAEVIDAVGAMADRLRRAVR---- TH_1858|M.thermoresistible__bu VTAGADDPQRIVLHLAAPGLPFEVLEPAEVAEAAAAVADLLTRASGRT-- Mflv_5106|M.gilvum_PYR-GCK VTVGADDPQRMVPWLAMPGCEFEVLEPDEVVDAVRVVAERIARAGAGGD- MAB_2185|M.abscessus_ATCC_1997 VEIDVASPDRLVRSIASHGADAVALEPAQVRDEVVARLQEQAGVTA---- MAV_2407|M.avium_104 IELDIRATDQLARDIAGYGADAVVLEPQSLRDDVLARLRAHAGADAVGAG Mvan_2933|M.vanbaalenii_PYR-1 IVIRGHNEYALAGELAGLIEWLEVTGPQGVRDHLASIGGALVARYS---- : :. :* . * : : MSMEG_1359|M.smegmatis_MC2_155 ---------- TH_1858|M.thermoresistible__bu ---------- Mflv_5106|M.gilvum_PYR-GCK ---------- MAB_2185|M.abscessus_ATCC_1997 ---------- MAV_2407|M.avium_104 RPGGRGGVSA Mvan_2933|M.vanbaalenii_PYR-1 ----------