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M. vanbaalenii PYR-1 Mvan_3434 (-)

annotation: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit
coordinates: 3650867 - 3652054
length: 395

IIVVGIGADGMAGLAPASRAELARATVVYGSRRQLELLDGTVTAPRRAWPTPLLPALGTLLDGGDADVHV
VASGDPMLHGIGSTLIRLHGPDKVAVLPHVSSVTLACARVGWSVQDTEIISLVWHEPHTAVRRGGQAVVL
SRDGSTPAELARLLTDAGRGDSELTVLEQLGGPKELRRTSTAREWAARPPADVDDLNVMAVRYLPDVRVL
GTLPDDAFAHDGQLTKQMIRAATLAALAPRPGELLWDVGAGSGSISIEWCRSGPGCRAIAFERDEARRAR
ITENAVAHGAGVEVRFDAPESFDSSPPPAAVFVGGGVSRPGMIDACWERLGPGGRLVANAVTVESEAVLA
QWYSRVGGELRRYQHYRGEAVGSFTGWRPAMPVTQWSVTKPDTT*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_3434 - - 100% (395) precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2098c cobLb 1e-116 68.03% (294) precorrin-6y methyltransferase
M. gilvum PYR-GCK Mflv_3101 - 1e-176 77.58% (388) precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT
M. tuberculosis H37Rv Rv2072c cobL 1e-153 68.54% (391) precorrin-6y methyltransferase CobL
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_2195 - 1e-119 56.82% (396) precorrin-6Y C5,15-methyltransferase CobL
M. marinum M MMAR_3054 cobL 1e-151 65.22% (391) precorrin-6y methyltransferase, CobL
M. avium 104 MAV_2424 cobL 1e-156 68.54% (391) precorrin-6Y C5,15-methyltransferase (decarboxylating)
M. smegmatis MC2 155 MSMEG_3878 cobL 1e-162 71.10% (391) precorrin-6Y C5,15-methyltransferase (decarboxylating)
M. thermoresistible (build 8) TH_0444 cobL 1e-164 73.91% (391) Probable precorrin-6y methyltransferase CobL
M. ulcerans Agy99 MUL_2298 cobL 1e-151 65.22% (391) precorrin-6y methyltransferase, CobL

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_3434|M.vanbaalenii_PYR-1       ------------------------------MIIVVGIGADGMAGLAPASR
Mflv_3101|M.gilvum_PYR-GCK          -----------------------------------------MSGLPEVSR
TH_0444|M.thermoresistible__bu      ------------------------------MITVVGIGADGMAGLSAESR
Mb2098c|M.bovis_AF2122/97           --------------------------------------------------
Rv2072c|M.tuberculosis_H37Rv        ------------------------------MIIVVGIGADGMTGLSEHSR
MMAR_3054|M.marinum_M               ------------------------------MIVVVGIGADGMPGLSDASR
MUL_2298|M.ulcerans_Agy99           ------------------------------MIVVVGIGADGIPGLSDASR
MAV_2424|M.avium_104                ------------------------------MIVVVGIGADGMAGLAEASR
MSMEG_3878|M.smegmatis_MC2_155      ----------------------------MKLIIVVGIGADGMPGLSAASR
MAB_2195|M.abscessus_ATCC_1997      MAQDAAMSPSGEEHGAPMSPSGHEPEAPTGRITVVGIGADGVDGLSARSR
                                                                                      

Mvan_3434|M.vanbaalenii_PYR-1       AELARATVVYGSRRQLELLDGT-VTAPRRAWPTPLLPALGTLLDGGDADV
Mflv_3101|M.gilvum_PYR-GCK          SELSRATVIYGSQRQLDLLDGT-VTAARRTWPSPLLPALPSLMDDSGGDI
TH_0444|M.thermoresistible__bu      AELARATVIYGSERQLGLLDDT-VTAERRAWPSPLLPALRSLDPDT--DP
Mb2098c|M.bovis_AF2122/97           --------------------------------------------------
Rv2072c|M.tuberculosis_H37Rv        SELRRATVIYGSKRQLALLDDT-VTAERWEWPTPMLPAVQGLSPDGA-DL
MMAR_3054|M.marinum_M               CELQRATIIYGSKRQLDLLDET-VTTSRREWPSPMLPALRQLPADGP-DI
MUL_2298|M.ulcerans_Agy99           CELQRATIIYGSKRQLDLLDET-VTASRPEWPSPMLPALQQLPADGP-DI
MAV_2424|M.avium_104                AELRSAAVIYGSKRQLDLLDDT-VPAPRRHWPSPMLPALQSLLDDHTGDV
MSMEG_3878|M.smegmatis_MC2_155      DELARATVVFGAPRQLALLDDT-VIADRREWPSPMLPALPTLFDDFGGDV
MAB_2195|M.abscessus_ATCC_1997      RELHRASVIFGSLRQLELLAEESLVAECRVWPSPLLPALPTMFDGLG-DV
                                                                                      

Mvan_3434|M.vanbaalenii_PYR-1       HVVASGDPMLHGIGSTLIRLHGPDKVAVLPHVSSVTLACARVGWSVQDTE
Mflv_3101|M.gilvum_PYR-GCK          HVIASGDPLLHGIGGTLITLLGAQRVAVLPHVSSVTLACARVGWPVQDTE
TH_0444|M.thermoresistible__bu      HVLASGDPLLHGIGATLIRHFGTDRVRILPHVSSVTLACARMGWPVQDTE
Mb2098c|M.bovis_AF2122/97           ----------------------------MPHVSAVTLACARMGWNVYDTE
Rv2072c|M.tuberculosis_H37Rv        HVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTE
MMAR_3054|M.marinum_M               HVVASGDPLMHGIGGTLIRLFGPEHVRVVPHVSAVTLACARMGWNVHDTE
MUL_2298|M.ulcerans_Agy99           HVVASGDPLMHGIGGTLIRLFGPEHVRVVPHVSAVTLACARMGWNVHDTE
MAV_2424|M.avium_104                HIVASGDPLLHGIGGTLIRLYGAGRVRVLPHVSSVTLACARMGWNVHDTE
MSMEG_3878|M.smegmatis_MC2_155      HVVASGDPLCHGIGATLIRLFGADRVRVLPHVSSVTLACARMGWTVPDTE
MAB_2195|M.abscessus_ATCC_1997      HVLASGDPMLHGIGTTLTRLFGAQRVDVHPHISSVSLACSRMGWAVNDIE
                                                                 **:*:*:***:*:** * * *

Mvan_3434|M.vanbaalenii_PYR-1       IISLVWHEPHTAVRRGGQAVVLSRDGSTPAELARLLTDAGRGDSELTVLE
Mflv_3101|M.gilvum_PYR-GCK          IISLVNADPHTAVRRGGQAVVLSRDGSTPAALARLLTDAGRGDSELTILE
TH_0444|M.thermoresistible__bu      VISVVTAEVHTAVRRGGRAVVLSRDGGTPAALARLLARTGRGESRLAVLE
Mb2098c|M.bovis_AF2122/97           VISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLE
Rv2072c|M.tuberculosis_H37Rv        VISLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLE
MMAR_3054|M.marinum_M               VISLVTAPPHTALRRGGQAIILSNSKATPSQLAALLHAHGRGDSEFSVLE
MUL_2298|M.ulcerans_Agy99           VISLVTAPPHTALRRGGQAIILSNSKATPSQLAALLHAHGSGDSEFSVLE
MAV_2424|M.avium_104                VISLVTGQPHTAVRRGGQAIVLSQGAATPTELAALLTAHGRGDSQFTVLE
MSMEG_3878|M.smegmatis_MC2_155      VISLVTAPPHTAVRRGGRAVVLSRDASTPTDLARLLTESGRGDSGFTVLE
MAB_2195|M.abscessus_ATCC_1997      IISLVNAPARSARRFGGRAVVLSRNAGTPRELAQTLSESGLGDSRLTVWE
                                    :**:*    ::* * **:*::** . .**  **  *   * *:* ::: *

Mvan_3434|M.vanbaalenii_PYR-1       QLGGPKELRRTSTAREWAARPPADVDDLNVMAVRYLPDVRV-----LGTL
Mflv_3101|M.gilvum_PYR-GCK          QLGGPGELRCSATAREWAARPPGDVDALNVIAVRYLPDARR-----HGAL
TH_0444|M.thermoresistible__bu      QLGGPRERRRDGTAERWAADPPTDVDDLNVIAVHYLPDARQ-----GQVL
Mb2098c|M.bovis_AF2122/97           QLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLPDER------TSWA
Rv2072c|M.tuberculosis_H37Rv        QLGGPAERRRDGTARAWACDPPLDVDELNVIAVRYLLDER------TSWA
MMAR_3054|M.marinum_M               QLGGRAERHRHGTARKWAAEAPVDVDDLNVIAIRYLPEAR------VLAP
MUL_2298|M.ulcerans_Agy99           QLGGPLERHRHGTARKWAAEAPVDVDDLNVIAIRYLPEAR------VLAP
MAV_2424|M.avium_104                RLGALDEHRRDGTARDWA-DGAADIDPLNVIAVRYLPDER------VWPL
MSMEG_3878|M.smegmatis_MC2_155      QLGGPGERRRDGTAADWSAAPAPDVDDLNVVAVTYRPEDRR-----AHAL
MAB_2195|M.abscessus_ATCC_1997      QLGGAGEHSFGGVARSWDHPLG---DALNVIAVEYVPAEEVAILPLVAGL
                                    :**.  *    ..*  *        * ***:*: *    .          

Mvan_3434|M.vanbaalenii_PYR-1       PDDAFAHDGQLTKQMIRAATLAALAPRPGELLWDVGAGSGSISIEWCRSG
Mflv_3101|M.gilvum_PYR-GCK          PDDAFAHDGQITKQAIRAATLAALAPRPGQLLWDVGAGSGSVSVEWCLAG
TH_0444|M.thermoresistible__bu      PDDQFDHDGQLTKQSIRAVTLAALAPRPGELLWDVGAGSGSIAIEWCRSA
Mb2098c|M.bovis_AF2122/97           PDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSW
Rv2072c|M.tuberculosis_H37Rv        PDEAFAHDGQITKHPIRVLTLAALAPRPGQRLWDVGAGSGAIAVQWCRSW
MMAR_3054|M.marinum_M               PDDAFAHDGQITKHGIRALTVAALAPRPGERLWDVGSGSGSIAVQWCRSW
MUL_2298|M.ulcerans_Agy99           PDDAFAHDGQITKHGIRALTVAALAPRPGERLWDVGSGSGSIAVQWCRSW
MAV_2424|M.avium_104                PDDAFTHDGQITKQRIRAVTLAALAPRPGERLWDVGAGSGSISVEWCLSG
MSMEG_3878|M.smegmatis_MC2_155      PDEQFSHDGQITKQSIRAVTLAALGPRPGELLWDVGSGSGSIAIEWCRSA
MAB_2195|M.abscessus_ATCC_1997      PESVFEHDGQITKHEIRAVTLAALGPRPGQRLWDVGAGSGSIAVEWSRSG
                                    *:. * ****:**: **. *:***.****: *****:***:::::*. : 

Mvan_3434|M.vanbaalenii_PYR-1       PGCRAIAFERDEARRARITENAVAHGAGVEVRFDAPESFDSSPPPAAVFV
Mflv_3101|M.gilvum_PYR-GCK          TGCRAVAFERDEARRARITVNANTFGVRIEVGSDAPDSFGMAPPPDAVFV
TH_0444|M.thermoresistible__bu      TGCRAVAFEQDEQRRERITANAAAFGAPVQVFGAAPAAFGGAPDPAAIFV
Mb2098c|M.bovis_AF2122/97           PGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFL
Rv2072c|M.tuberculosis_H37Rv        PGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDAFDDAARPSVIFL
MMAR_3054|M.marinum_M               PGCTAVAFERDERRRANIESNAVSFGVSIDARGEAPLAFEGTAEPSAIFL
MUL_2298|M.ulcerans_Agy99           PGCTAVAFERDERRRANIESNAVSFGVSVDARGEAPLAFEGTAEPSAIFL
MAV_2424|M.avium_104                TGCRATAFERDAQRRHNLAANAAAFGAAIDVRGDAPHAFVGAEPPSAIFI
MSMEG_3878|M.smegmatis_MC2_155      PGCTAVAFERDEQRRDRIRANVEAFGVRVDLRGAAPECFDGAPAPAAIFI
MAB_2195|M.abscessus_ATCC_1997      TGCSASAFEIEPSRRASIAANATKFGVDIDVFGAAPDDFEQAVAPDVIFV
                                    .** * *** :  **  :  *.  .*. ::    **  *  :  * .:*:

Mvan_3434|M.vanbaalenii_PYR-1       GGGVSRPGMIDACWERLGPGGRLVANAVTVESEAVLAQWYSRVGGELRRY
Mflv_3101|M.gilvum_PYR-GCK          GGGVSSPGLLQACWDALRDGGRMVVNAVTVESEAVLAHWYSQHGGELRRF
TH_0444|M.thermoresistible__bu      GGGVTGDGLLEACLQRLPAGGRLVANAVTAESEAVLAQWYSERGGELRRY
Mb2098c|M.bovis_AF2122/97           GGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRF
Rv2072c|M.tuberculosis_H37Rv        GGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELRRF
MMAR_3054|M.marinum_M               GGGLTQPGLLDSCLGHLPTGGRLVANVVTAESEAALVHAHSRLGGQLRRF
MUL_2298|M.ulcerans_Agy99           GGGLTQPGLLDSCLGHLPTGGRLVANVVTAESEAALVHAHSRLGGQLRRF
MAV_2424|M.avium_104                GGGLTRPGLLDACFDHLPSGGRLVANVVTTESEAVVIQAYTRFGGQLRRF
MSMEG_3878|M.smegmatis_MC2_155      GGGVTGPGVLEACFDRLSTGGRLVVNAVTVESEAVVAQWYSEKGGDLRRY
MAB_2195|M.abscessus_ATCC_1997      GGGVTQPGLLEACWERLPIGGRMVVNAVTAESEALLLRWYCRYGGELRRY
                                    ***::  *::::*   *  **.:*.*.**.**** : : : . **:***:

Mvan_3434|M.vanbaalenii_PYR-1       QHYRGEAVGSFTGWRPAMPVTQWSVTK----PDTT
Mflv_3101|M.gilvum_PYR-GCK          QHYRGEAVGTFTGWRPAMPVTQWSVTKAVSMPDTT
TH_0444|M.thermoresistible__bu      QHYRGEPIGRFTGWRPAYPVTQWSVTKR-------
Mb2098c|M.bovis_AF2122/97           QHYLGEPLGGFTGWRPQLPVTQWSVTKR-------
Rv2072c|M.tuberculosis_H37Rv        QHYLGEPLGGFTGWRPQLPVTQWSVTKR-------
MMAR_3054|M.marinum_M               QHYQGEPLGGFTGWRPQMPVTQWAVTKR-------
MUL_2298|M.ulcerans_Agy99           QHYQGEPLGGFTGWRPQMPVTQWAVTKR-------
MAV_2424|M.avium_104                QHYHGKALGAFTGWHPQFPVTQWAVTR--------
MSMEG_3878|M.smegmatis_MC2_155      QHYQGGAVGGFTAWRPALPVTQWSVVKA-------
MAB_2195|M.abscessus_ATCC_1997      RVEDAAPLGGFTSWRSRLPVVQWSTEKS-------
                                    :   . .:* **.*:.  **.**:. :

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_3434	-	-	100% (395)	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit