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GYSAADESFTHQLPTTFDQVHDPDPTWSDRCYFFAASPDGTMLLASGYGNNPNTATGLGYVKVSLADGRH WDLLAGRPVTGGDRDDLAAGPMRWTCVEPLKKWRLDVTPNDSGIEWELYYEPTAPMWELLPMKVRDNDGR VLADMYHMKEPGRWTGWVKIDGERISVDGFHGGRDRTFGVRVSDKIDFWLWLDAGFEDQAIEAWVIESSD GTVHYVDGGITRTDGTLSKRFVKIDHDVTFDAGRKRPAGAVLVFTDEDGQTYRVTADSPHRHVNAYYGLP MSHCRYQDLGDGGYFIHFRWDSDDAGQLAETEDKSMALDQLMRFDFDGRTGWGVFELLMGGAGYRRYPNW PAMDMTSFTQDKTPVDRLQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3398 | - | - | 100% (371) | hypothetical protein Mvan_3398 |
| M. vanbaalenii PYR-1 | Mvan_1820 | - | 2e-14 | 24.39% (287) | hypothetical protein Mvan_1820 |
| M. vanbaalenii PYR-1 | Mvan_1868 | - | 4e-14 | 26.05% (357) | hypothetical protein Mvan_1868 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3194 | - | 4e-16 | 26.82% (358) | hypothetical protein Mb3194 |
| M. gilvum PYR-GCK | Mflv_4498 | - | 7e-12 | 25.17% (298) | hypothetical protein Mflv_4498 |
| M. tuberculosis H37Rv | Rv3169 | - | 4e-16 | 26.82% (358) | hypothetical protein Rv3169 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4483 | - | 2e-14 | 28.38% (303) | hypothetical protein MAB_4483 |
| M. marinum M | MMAR_1392 | - | 3e-14 | 26.53% (294) | hypothetical protein MMAR_1392 |
| M. avium 104 | MAV_5274 | - | 0.0 | 84.01% (369) | hypothetical protein MAV_5274 |
| M. smegmatis MC2 155 | MSMEG_4982 | - | 1e-19 | 25.65% (386) | hypothetical protein MSMEG_4982 |
| M. thermoresistible (build 8) | TH_0414 | - | 3e-18 | 25.86% (290) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2484 | - | 2e-14 | 26.53% (294) | hypothetical protein MUL_2484 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1392|M.marinum_M MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFVIS
MUL_2484|M.ulcerans_Agy99 MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFVIS
Mb3194|M.bovis_AF2122/97 MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFLIT
Rv3169|M.tuberculosis_H37Rv MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFLIT
Mflv_4498|M.gilvum_PYR-GCK ---MLGPMDEFPVHQIPQPIAWPGSSDRNFYDRSYFNAHD-RTGDIFVIT
MAB_4483|M.abscessus_ATCC_1997 --MSLSPFDDYPIHQIADVVRHVGTSDRNFYDRYYFGCHGGRADLPYLIT
MSMEG_4982|M.smegmatis_MC2_155 ---MLTPHDELLCHQLPTTFDHVDQSDLRWTERIVMYGFD-RSGDINVMT
TH_0414|M.thermoresistible__bu ---VLTPYDELMCHQLSTTFDHVAQSDLRWTERVVIYGFD-PESLTSVMT
Mvan_3398|M.vanbaalenii_PYR-1 --MGYSAADESFTHQLPTTFDQVHDPDPTWSDRCYFFAAS-PDGTMLLAS
MAV_5274|M.avium_104 --MGYSAADESFTHQLPTTFDQVHDADPTWSDRCYFFAAA-PDGTMLLAS
. *: **:. . .* : :* : . : :
MMAR_1392|M.marinum_M GIGYYPNLGVKDAFLLIR-RGDTQTAVHLSDAIDQDRLH----------Q
MUL_2484|M.ulcerans_Agy99 GIGYYPNLGVKDAFLLIR-RGDTQTAVHLSDAIDQDRLH----------Q
Mb3194|M.bovis_AF2122/97 GIGYYPNLGVKDAFVLIR-RADIQTAVHLSDAIDSDRLH----------Q
Rv3169|M.tuberculosis_H37Rv GIGYYPNLGVKDAFVLIR-RADIQTAVHLSDAIDSDRLH----------Q
Mflv_4498|M.gilvum_PYR-GCK GLGYYPNLGVKDAFFLVR-RGDTQTAVHLSDAIDQDRLN----------Q
MAB_4483|M.abscessus_ATCC_1997 GLGVYPNLGVTDAFASVR-NGDDIVVFRASRALGDDRAD----------L
MSMEG_4982|M.smegmatis_MC2_155 GLARYPNRNVTDAYAMITRRDATARVVRMSTELNPETG--PLGS-----Y
TH_0414|M.thermoresistible__bu GMARYPNRNVTDAYAMVT-VDGQAHVVRTSREIVPFGGENPGGTDGLTFW
Mvan_3398|M.vanbaalenii_PYR-1 GYGNNPNTATGLGYVKVSLADGRHWDLLAGRPVTGGDRD---------DL
MAV_5274|M.avium_104 GYGNNPNTASGLGYVKVSLADGRHWDLLSGRPVTGDDRG---------EL
* . ** .: : . . :
MMAR_1392|M.marinum_M HVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPHL
MUL_2484|M.ulcerans_Agy99 HVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPHL
Mb3194|M.bovis_AF2122/97 HVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPHV
Rv3169|M.tuberculosis_H37Rv HVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPHV
Mflv_4498|M.gilvum_PYR-GCK HVGNYRVEVIEPLRKLRIVLD-----ETDGIAADLTWEGLFDAVQEQPHI
MAB_4483|M.abscessus_ATCC_1997 TVGPYRIEVVEGLKKVRVILEPGWHDATYDISFDLTYTGEIPASLEPGHY
MSMEG_4982|M.smegmatis_MC2_155 SVGPYTYTIEEPLRTVRAVLAPNE----QGVSLDLRLRGQFPTYEQTPAF
TH_0414|M.thermoresistible__bu SVGPYRYEVREPLRRVRATLEPG-----HGLALDVDFAGTFDCYEQAPAF
Mvan_3398|M.vanbaalenii_PYR-1 AAGPMRWTCVEPLKKWRLDVTPN----DSGIEWELYYEPTAPMWELLPMK
MAV_5274|M.avium_104 RAGPMRWTCVEPLKKWRLDVGPN----NSGIEWELYYEPTAPMWELLPMK
.. * *: * : .: ::
MMAR_1392|M.marinum_M LRS-GNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIR
MUL_2484|M.ulcerans_Agy99 LRS-GNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIR
Mb3194|M.bovis_AF2122/97 LRS-GNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIR
Rv3169|M.tuberculosis_H37Rv LRS-GNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIR
Mflv_4498|M.gilvum_PYR-GCK MRR-GTRVTLNAQRFAQVGSWSGQLSIDGTDIAVDPAQWIGTRDRSWGIR
MAB_4483|M.abscessus_ATCC_1997 QRQ-LGRVMFDTSRFAQTGTWTGQLTIDGTTHELDGVNWSGNRDRSWGIR
MSMEG_4982|M.smegmatis_MC2_155 HRS-RGRVSEDARRFYQNGQVEGWIEIDGERIEIDPGSWWFGRDHSWGIR
TH_0414|M.thermoresistible__bu FRD-RGRVDEDARRFYQVGRASGGITVGDRRIDID-DSWHFGRDHSWGVR
Mvan_3398|M.vanbaalenii_PYR-1 VRDNDGRVLADMYHMKEPGRWTGWVKIDGERISVD--GFHGGRDRTFGVR
MAV_5274|M.avium_104 VSGPDGRLLADMYHMKEPGRWSGWVRIDGQRVSVD--GFHGGRDRTFGVR
*: : :: : * * : :.. :* : **:::*:*
MMAR_1392|M.marinum_M PVGEP----EPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRS
MUL_2484|M.ulcerans_Agy99 PVGEP----EPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRS
Mb3194|M.bovis_AF2122/97 PVGEP----EPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRS
Rv3169|M.tuberculosis_H37Rv PVGEP----EPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRS
Mflv_4498|M.gilvum_PYR-GCK PIGEA----EPAGRPDDPPFEGMWWLYIPMAFDDFGIVIIIQEDPLGFRS
MAB_4483|M.abscessus_ATCC_1997 PVGEG----EPAGRRAT-LAGGFFWLYNVISFPQYSIVFINQEDEHGNKV
MSMEG_4982|M.smegmatis_MC2_155 NGPGGGSLSEGAHLQPQEIPDGTLYYMGIFQFDDELVHFAQRETSTGERW
TH_0414|M.thermoresistible__bu RGGGGGDLPETSILQPRTIPDGVLYFMGIFEFDDRLVHFAQRETADGEVF
Mvan_3398|M.vanbaalenii_PYR-1 VSDKID-----------------FWLWLDAGFEDQAIEAWVIESSDGTVH
MAV_5274|M.avium_104 VSDRID-----------------FWLWLDAGFGDHAIEAWVIESCDGTVL
: * : : * *
MMAR_1392|M.marinum_M LNDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPV
MUL_2484|M.ulcerans_Agy99 LNDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPV
Mb3194|M.bovis_AF2122/97 LNDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPV
Rv3169|M.tuberculosis_H37Rv LNDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPV
Mflv_4498|M.gilvum_PYR-GCK LNDCTRVWKDGR---VEQLGWPRVKIQYRSGTRIPTGATVEATALDGSPL
MAB_4483|M.abscessus_ATCC_1997 VSGARRVWRDPSKG-IEELGPIAHDITLIPGTREARSAVVTLG-----DI
MSMEG_4982|M.smegmatis_MC2_155 QFEGEVLYPIETGRPAGTIIDVEHDLKFRDDLRVISGGTFTVHRGDRTTS
TH_0414|M.thermoresistible__bu HYEGEMLAPSSTGRPSTPITRVSHDFTFRDDLRVISGGKVTIHTADGSAE
Mvan_3398|M.vanbaalenii_PYR-1 YVDGGITRTDGT--LSKRFVKIDHDVTFDAGRKRPAGAVLVFTDEDGQTY
MAV_5274|M.avium_104 YADGGITYADGT--LSKRFVKIEHEVEFDGERKRPARAVLVFTDEDGRAH
: . : . .
MMAR_1392|M.marinum_M HFDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIAR
MUL_2484|M.ulcerans_Agy99 HFDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIAR
Mb3194|M.bovis_AF2122/97 HFDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIAR
Rv3169|M.tuberculosis_H37Rv HFDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIAR
Mflv_4498|M.gilvum_PYR-GCK HFDVESKLAVPIHVGGGYGGDSDWLHGVWKGPNFTERLTYDMTDPAVIGR
MAB_4483|M.abscessus_ATCC_1997 TITADIVLPHYFGFGTGYGLDPDWRHGMWQGDLVVQGKRYKTAELDATLK
MSMEG_4982|M.smegmatis_MC2_155 TIEVRPMTDFWPGLAG-YMEVDGYASGHWRGRDFIDGFTADIGDIDVVKP
TH_0414|M.thermoresistible__bu DITITPLTGFWPGFAG-YDEYRGYASGHWRGPSYVDSFVVDTTDPAEVGQ
Mvan_3398|M.vanbaalenii_PYR-1 RVTADSPHRHVNAYYGLPMSHCRYQD--LGDGGYFIHFRWDSDDAGQLAE
MAV_5274|M.avium_104 RVVAEAPHPQVNAYYGLPMAHCHYED--LGGGSYFIHFAWDSSDPEQLSE
. : . :
MMAR_1392|M.marinum_M SGFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP-
MUL_2484|M.ulcerans_Agy99 SGFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP-
Mb3194|M.bovis_AF2122/97 AGFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP-
Rv3169|M.tuberculosis_H37Rv AGFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP-
Mflv_4498|M.gilvum_PYR-GCK AGFGVIDHVGRAVCREADGTEREGWGLFEHGALGRHDPSGFADWLTVAP-
MAB_4483|M.abscessus_ATCC_1997 L-LCPVDNLATFRLIEN-GVETHGSGLFEFGPIGPHKPSGFTGFVDTHQE
MSMEG_4982|M.smegmatis_MC2_155 VSFLSETLCE--VSMDSGSGPKIGHGLVEMVFVGAYPRYGYTGW------
TH_0414|M.thermoresistible__bu VSLLSETFCR--VRC----GDAVGHGLVEMVFVGRNERYGYAGY------
Mvan_3398|M.vanbaalenii_PYR-1 T---EDKSMALDQLMRFDFDGRTGWGVFELLMGGAGYRR-YPNWPAMDMT
MAV_5274|M.avium_104 T---EDKSMALDQLMRFERDGHTGWGIFELLLGGQGYRR-YPNWRAMDMS
* *: * * :..:
MMAR_1392|M.marinum_M ---------------------
MUL_2484|M.ulcerans_Agy99 ---------------------
Mb3194|M.bovis_AF2122/97 ---------------------
Rv3169|M.tuberculosis_H37Rv ---------------------
Mflv_4498|M.gilvum_PYR-GCK ---------------------
MAB_4483|M.abscessus_ATCC_1997 RDSDS----------------
MSMEG_4982|M.smegmatis_MC2_155 ---------------------
TH_0414|M.thermoresistible__bu ---------------------
Mvan_3398|M.vanbaalenii_PYR-1 SFTQDKTPVDRLQS-------
MAV_5274|M.avium_104 AFTQDKTPVDRLPADGDGADR