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NLSPLDEYPIHQVPAPITSPATSDRNFYDRSYFNVLDRDGRFMALTGIGYYPRLGVKDAYFLVRRGDTQT AVHLSDALDDDRFHQNVNGYRLDVVEPLQELHLTLAETEGVSADLTWRGLYPAALERPHEMLTERRVTLQ ACRFAQVGSWQGWIEIDGDRLTVDHTTSVGSRDRSWGIRPVGEPEPAGRPDAAFGGMWWLYLPLAFDDYQ LFLILQEDPDGHRSLYDCTRRWRDGRVEQLDGVRATIHYTPGTRIPYGAHVEFMNRAGDRIQLNVESKLF APIAFGSGYGGDSSWAHGTWKGGPFSERVSFDLTDPAVMARAPFSLIDHVGTAVCTESDGRTSEGAGLFE HGVIGPHHPSGFSDWTDVAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1820 | - | - | 100% (371) | hypothetical protein Mvan_1820 |
| M. vanbaalenii PYR-1 | Mvan_1868 | - | e-138 | 60.98% (369) | hypothetical protein Mvan_1868 |
| M. vanbaalenii PYR-1 | Mvan_3398 | - | 2e-14 | 24.39% (287) | hypothetical protein Mvan_3398 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3194 | - | 1e-141 | 62.33% (369) | hypothetical protein Mb3194 |
| M. gilvum PYR-GCK | Mflv_4498 | - | 1e-138 | 61.79% (369) | hypothetical protein Mflv_4498 |
| M. tuberculosis H37Rv | Rv3169 | - | 1e-141 | 62.33% (369) | hypothetical protein Rv3169 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4483 | - | 6e-66 | 40.53% (380) | hypothetical protein MAB_4483 |
| M. marinum M | MMAR_1392 | - | 1e-142 | 62.87% (369) | hypothetical protein MMAR_1392 |
| M. avium 104 | MAV_4060 | - | 1e-141 | 62.87% (369) | hypothetical protein MAV_4060 |
| M. smegmatis MC2 155 | MSMEG_4982 | - | 6e-29 | 29.10% (378) | hypothetical protein MSMEG_4982 |
| M. thermoresistible (build 8) | TH_0686 | - | 1e-135 | 59.79% (378) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2484 | - | 1e-142 | 62.87% (369) | hypothetical protein MUL_2484 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3194|M.bovis_AF2122/97 MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFLIT
Rv3169|M.tuberculosis_H37Rv MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFLIT
MMAR_1392|M.marinum_M MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFVIS
MUL_2484|M.ulcerans_Agy99 MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFVIS
MAV_4060|M.avium_104 ---MLGPLDEYPVHQIPQPIAWPGSSDRNFYDRSYFNAHD-RTGNIFVIS
TH_0686|M.thermoresistible__bu ---MLGPLDEFPVHQIPQPIAWPGSSDRNFYDRSYLNAHD-RTGDIFLIT
Mflv_4498|M.gilvum_PYR-GCK ---MLGPMDEFPVHQIPQPIAWPGSSDRNFYDRSYFNAHD-RTGDIFVIT
Mvan_1820|M.vanbaalenii_PYR-1 --MNLSPLDEYPIHQVPAPITSPATSDRNFYDRSYFNVLD-RDGRFMALT
MAB_4483|M.abscessus_ATCC_1997 --MSLSPFDDYPIHQIADVVRHVGTSDRNFYDRYYFGCHGGRADLPYLIT
MSMEG_4982|M.smegmatis_MC2_155 ---MLTPHDELLCHQLPTTFDHVDQSDLRWTERIVMYGFD-RSGDINVMT
* * *: **:. . ** .: :* : . * . ::
Mb3194|M.bovis_AF2122/97 GIGYYPNLGVKDAFVLIRR---------ADIQTAVHLSDAIDSDR---LH
Rv3169|M.tuberculosis_H37Rv GIGYYPNLGVKDAFVLIRR---------ADIQTAVHLSDAIDSDR---LH
MMAR_1392|M.marinum_M GIGYYPNLGVKDAFLLIRR---------GDTQTAVHLSDAIDQDR---LH
MUL_2484|M.ulcerans_Agy99 GIGYYPNLGVKDAFLLIRR---------GDTQTAVHLSDAIDQDR---LH
MAV_4060|M.avium_104 GIGYYPNLGVKDAFFLVRR---------GDTQTAVHLCDAIDQDR---LN
TH_0686|M.thermoresistible__bu GIGYYPNLGVKDAFVLLARRGSGTSGGCGETQTAVHLSDAIDQDR---LN
Mflv_4498|M.gilvum_PYR-GCK GLGYYPNLGVKDAFFLVRR---------GDTQTAVHLSDAIDQDR---LN
Mvan_1820|M.vanbaalenii_PYR-1 GIGYYPRLGVKDAYFLVRR---------GDTQTAVHLSDALDDDR---FH
MAB_4483|M.abscessus_ATCC_1997 GLGVYPNLGVTDAFASVRN---------GDDIVVFRASRALGDDR---AD
MSMEG_4982|M.smegmatis_MC2_155 GLARYPNRNVTDAYAMITRR--------DATARVVRMSTELNPETGPLGS
*:. **. .*.**: : . ..: . :. :
Mb3194|M.bovis_AF2122/97 QHVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPH
Rv3169|M.tuberculosis_H37Rv QHVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPH
MMAR_1392|M.marinum_M QHVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPH
MUL_2484|M.ulcerans_Agy99 QHVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPH
MAV_4060|M.avium_104 QHVNGYRIEVKEPLRKLRLVLD-----ETEGVAADLTWEGLFDVVQEQPH
TH_0686|M.thermoresistible__bu QHVNGYRIEVLEPLRKLRVVLE-----ETEGMAVDLTWEGLFDPVQEQPH
Mflv_4498|M.gilvum_PYR-GCK QHVGNYRVEVIEPLRKLRIVLD-----ETDGIAADLTWEGLFDAVQEQPH
Mvan_1820|M.vanbaalenii_PYR-1 QNVNGYRLDVVEPLQELHLTLA-----ETEGVSADLTWRGLYPAALERPH
MAB_4483|M.abscessus_ATCC_1997 LTVGPYRIEVVEGLKKVRVILEPGWHDATYDISFDLTYTGEIPASLEPGH
MSMEG_4982|M.smegmatis_MC2_155 YSVGPYTYTIEEPLRTVRAVLAP----NEQGVSLDLRLRGQFPTYEQTPA
*. * : * *: :: * .:: ** * :
Mb3194|M.bovis_AF2122/97 VLRSGNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIR
Rv3169|M.tuberculosis_H37Rv VLRSGNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIR
MMAR_1392|M.marinum_M LLRSGNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIR
MUL_2484|M.ulcerans_Agy99 LLRSGNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIR
MAV_4060|M.avium_104 ILRSGNRVTLDAQRFAQLGSWSGRIVIDGQEIAVDPATWIGSRDRSWGIR
TH_0686|M.thermoresistible__bu VLRSGNRVTLDAQRFAQVGTWSGVIVVDGEEIAVDPRHWIGTRDRSWGIR
Mflv_4498|M.gilvum_PYR-GCK IMRRGTRVTLNAQRFAQVGSWSGQLSIDGTDIAVDPAQWIGTRDRSWGIR
Mvan_1820|M.vanbaalenii_PYR-1 EMLTERRVTLQACRFAQVGSWQGWIEIDGDRLTVDHTTSVGSRDRSWGIR
MAB_4483|M.abscessus_ATCC_1997 YQRQLGRVMFDTSRFAQTGTWTGQLTIDGTTHELDGVNWSGNRDRSWGIR
MSMEG_4982|M.smegmatis_MC2_155 FHRSRGRVSEDARRFYQNGQVEGWIEIDGERIEIDPGSWWFGRDHSWGIR
** :: ** * * * : :** :* **:*****
Mb3194|M.bovis_AF2122/97 --PVGE--PEPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRS
Rv3169|M.tuberculosis_H37Rv --PVGE--PEPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRS
MMAR_1392|M.marinum_M --PVGE--PEPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRS
MUL_2484|M.ulcerans_Agy99 --PVGE--PEPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRS
MAV_4060|M.avium_104 --PIGE--PEPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEQPDGFRS
TH_0686|M.thermoresistible__bu --PIGE--PEPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPDGFRS
Mflv_4498|M.gilvum_PYR-GCK --PIGE--AEPAGRPDDPPFEGMWWLYIPMAFDDFGIVIIIQEDPLGFRS
Mvan_1820|M.vanbaalenii_PYR-1 --PVGE--PEPAGRP-DAAFGGMWWLYLPLAFDDYQLFLILQEDPDGHRS
MAB_4483|M.abscessus_ATCC_1997 --PVGE--GEPAGRR-ATLAGGFFWLYNVISFPQYSIVFINQEDEHGNKV
MSMEG_4982|M.smegmatis_MC2_155 NGPGGGSLSEGAHLQPQEIPDGTLYYMGIFQFDDELVHFAQRETSTGERW
* * * * * : : * : : : :* * :
Mb3194|M.bovis_AF2122/97 LNDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPV
Rv3169|M.tuberculosis_H37Rv LNDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPV
MMAR_1392|M.marinum_M LNDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPV
MUL_2484|M.ulcerans_Agy99 LNDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPV
MAV_4060|M.avium_104 LNDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDASAPDGTPV
TH_0686|M.thermoresistible__bu LNDCTRIFRDGR---VEQLGWPRVQIHYTSGTRIPYGATITASTPDGTPL
Mflv_4498|M.gilvum_PYR-GCK LNDCTRVWKDGR---VEQLGWPRVKIQYRSGTRIPTGATVEATALDGSPL
Mvan_1820|M.vanbaalenii_PYR-1 LYDCTRRWRDGR---VEQLDGVRATIHYTPGTRIPYGAHVEFMNRAGDRI
MAB_4483|M.abscessus_ATCC_1997 VSGARRVWRDPSK-GIEELGPIAHDITLIPGTREARSAVVTLG-----DI
MSMEG_4982|M.smegmatis_MC2_155 QFEGEVLYPIETGRPAGTIIDVEHDLKFRDDLRVISGGTFTVHRGDRTTS
: : : . * .. .
Mb3194|M.bovis_AF2122/97 HFDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIAR
Rv3169|M.tuberculosis_H37Rv HFDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIAR
MMAR_1392|M.marinum_M HFDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIAR
MUL_2484|M.ulcerans_Agy99 HFDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIAR
MAV_4060|M.avium_104 HFDVESKLPVPIHVGGGYGGDSDWLHGMWKGEKFTERLTYDMTDPAIIAR
TH_0686|M.thermoresistible__bu VFEVESKLAVPIHIGGGYGGDSDWLHGMWKGEKFTERLTYDMTDPSVSGR
Mflv_4498|M.gilvum_PYR-GCK HFDVESKLAVPIHVGGGYGGDSDWLHGVWKGPNFTERLTYDMTDPAVIGR
Mvan_1820|M.vanbaalenii_PYR-1 QLNVESKLFAPIAFGSGYGGDSSWAHGTWKGGPFSERVSFDLTDPAVMAR
MAB_4483|M.abscessus_ATCC_1997 TITADIVLPHYFGFGTGYGLDPDWRHGMWQGDLVVQGKRYKTAELDATLK
MSMEG_4982|M.smegmatis_MC2_155 TIEVRPMTDFWPGLAG-YMEVDGYASGHWRGRDFIDGFTADIGD--IDVV
: . .. * .: * *:* . : :
Mb3194|M.bovis_AF2122/97 AGFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP-
Rv3169|M.tuberculosis_H37Rv AGFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP-
MMAR_1392|M.marinum_M SGFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP-
MUL_2484|M.ulcerans_Agy99 SGFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP-
MAV_4060|M.avium_104 SGFGVIDHVGRAICRDGDKAPVEGWGLYEHGALGRHDPSGFSDWLTVAP-
TH_0686|M.thermoresistible__bu AMFGVIDHVGRATCH-IDGRTVEGWGLFEHGALGRHDPSGFTDWMSVAP-
Mflv_4498|M.gilvum_PYR-GCK AGFGVIDHVGRAVCREADGTEREGWGLFEHGALGRHDPSGFADWLTVAP-
Mvan_1820|M.vanbaalenii_PYR-1 APFSLIDHVGTAVCTESDGRTSEGAGLFEHGVIGPHHPSGFSDWTDVAD-
MAB_4483|M.abscessus_ATCC_1997 L-LCPVDNLA-TFRLIENGVETHGSGLFEFGPIGPHKPSGFTGFVDTHQE
MSMEG_4982|M.smegmatis_MC2_155 KPVSFLSETLCEVSMDSGSGPKIGHGLVEMVFVGAYPRYGYTGW------
. :.. . * ** * :* : *::.:
Mb3194|M.bovis_AF2122/97 -----
Rv3169|M.tuberculosis_H37Rv -----
MMAR_1392|M.marinum_M -----
MUL_2484|M.ulcerans_Agy99 -----
MAV_4060|M.avium_104 -----
TH_0686|M.thermoresistible__bu -----
Mflv_4498|M.gilvum_PYR-GCK -----
Mvan_1820|M.vanbaalenii_PYR-1 -----
MAB_4483|M.abscessus_ATCC_1997 RDSDS
MSMEG_4982|M.smegmatis_MC2_155 -----