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M. thermoresistible (build 8) TH_0414 (-)

annotation: conserved hypothetical protein
coordinates: 899998 - 901125
length: 376

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0414--100% (376)conserved hypothetical protein
M. thermoresistible (build 8)TH_4622-4e-3429.05% (389) PUTATIVE putative conserved hypothetical protein
M. thermoresistible (build 8)TH_0686-5e-2627.58% (388) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3194-4e-2828.39% (384) hypothetical protein Mb3194
M. gilvum PYR-GCKMflv_4498-2e-2628.17% (394) hypothetical protein Mflv_4498
M. tuberculosis H37RvRv3169-4e-2828.39% (384) hypothetical protein Rv3169
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4483-1e-2426.80% (388) hypothetical protein MAB_4483
M. marinum MMMAR_1392-1e-2426.30% (384) hypothetical protein MMAR_1392
M. avium 104MAV_4060-2e-2526.92% (390) hypothetical protein MAV_4060
M. smegmatis MC2 155MSMEG_4982-1e-12559.16% (382) hypothetical protein MSMEG_4982
M. ulcerans Agy99MUL_2484-8e-2526.30% (384) hypothetical protein MUL_2484
M. vanbaalenii PYR-1Mvan_1868-2e-2527.99% (393) hypothetical protein Mvan_1868

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1392|M.marinum_M               MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHDRTGNI-FVIS
MUL_2484|M.ulcerans_Agy99           MPQPLGPLDEYPVHQLPQPIAWPGSSDRNFYDRSYFNAHDRTGNI-FVIS
MAV_4060|M.avium_104                ---MLGPLDEYPVHQIPQPIAWPGSSDRNFYDRSYFNAHDRTGNI-FVIS
Mb3194|M.bovis_AF2122/97            MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHDRTGNI-FLIT
Rv3169|M.tuberculosis_H37Rv         MPQMLGPLDEYPLHQLPQPIAWPGSSDRNFYDRSYFNAHDRTGNI-FLIT
Mflv_4498|M.gilvum_PYR-GCK          ---MLGPMDEFPVHQIPQPIAWPGSSDRNFYDRSYFNAHDRTGDI-FVIT
Mvan_1868|M.vanbaalenii_PYR-1       ---MLGPMDEYPVHQVPQPIAWPGSSDRNFYDRAYYNAHDRTGDI-FVIT
MAB_4483|M.abscessus_ATCC_1997      --MSLSPFDDYPIHQIADVVRHVGTSDRNFYDRYYFGCHGGRADLPYLIT
TH_0414|M.thermoresistible__bu      ---VLTPYDELMCHQLSTTFDHVAQSDLRWTERVVIYGFDPESLT-SVMT
MSMEG_4982|M.smegmatis_MC2_155      ---MLTPHDELLCHQLPTTFDHVDQSDLRWTERIVMYGFDRSGDI-NVMT
                                        * * *:   **:.  .     ** .: :*     ..  .    :::

MMAR_1392|M.marinum_M               GIGYYPNLGVKDAFLLIR-RGDTQTAVHLSDAIDQDRLH----------Q
MUL_2484|M.ulcerans_Agy99           GIGYYPNLGVKDAFLLIR-RGDTQTAVHLSDAIDQDRLH----------Q
MAV_4060|M.avium_104                GIGYYPNLGVKDAFFLVR-RGDTQTAVHLCDAIDQDRLN----------Q
Mb3194|M.bovis_AF2122/97            GIGYYPNLGVKDAFVLIR-RADIQTAVHLSDAIDSDRLH----------Q
Rv3169|M.tuberculosis_H37Rv         GIGYYPNLGVKDAFVLIR-RADIQTAVHLSDAIDSDRLH----------Q
Mflv_4498|M.gilvum_PYR-GCK          GLGYYPNLGVKDAFFLVR-RGDTQTAVHLSDAIDQDRLN----------Q
Mvan_1868|M.vanbaalenii_PYR-1       GIGYYPNLGVKDAFLLAR-RGDTQTAVHLSDAIDQDRLN----------Q
MAB_4483|M.abscessus_ATCC_1997      GLGVYPNLGVTDAFASVR-NGDDIVVFRASRALGDDRAD----------L
TH_0414|M.thermoresistible__bu      GMARYPNRNVTDAYAMVT-VDGQAHVVRTSREIVPFGGENPGGTDGLTFW
MSMEG_4982|M.smegmatis_MC2_155      GLARYPNRNVTDAYAMITRRDATARVVRMSTELNPETG--PLGS-----Y
                                    *:. *** .*.**:           ..: .  :                 

MMAR_1392|M.marinum_M               HVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPHL
MUL_2484|M.ulcerans_Agy99           HVNGYRIDVIEPLRKLRLVLD-----ETEGVSADLTWEGLFDVVAEQPHL
MAV_4060|M.avium_104                HVNGYRIEVKEPLRKLRLVLD-----ETEGVAADLTWEGLFDVVQEQPHI
Mb3194|M.bovis_AF2122/97            HVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPHV
Rv3169|M.tuberculosis_H37Rv         HVNGYRVEVVEPLRKLRIVLD-----ETEGVAADLTWEGLFDVVQEQPHV
Mflv_4498|M.gilvum_PYR-GCK          HVGNYRVEVIEPLRKLRIVLD-----ETDGIAADLTWEGLFDAVQEQPHI
Mvan_1868|M.vanbaalenii_PYR-1       HVGNYRVEVIEPLRKLRIVLD-----ETEGIAADLTWEGLFDVVQEQPHI
MAB_4483|M.abscessus_ATCC_1997      TVGPYRIEVVEGLKKVRVILEPGWHDATYDISFDLTYTGEIPASLEPGHY
TH_0414|M.thermoresistible__bu      SVGPYRYEVREPLRRVRATLEPG-----HGLALDVDFAGTFDCYEQAPAF
MSMEG_4982|M.smegmatis_MC2_155      SVGPYTYTIEEPLRTVRAVLAPNE----QGVSLDLRLRGQFPTYEQTPAF
                                     *. *   : * *: :*  *         .:: *:   * :    :    

MMAR_1392|M.marinum_M               LRSGNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIRP
MUL_2484|M.ulcerans_Agy99           LRSGNRVTLDAQRFAQLGTWSGQIQVDGQQIDVDPATWIGSRDRSWGIRP
MAV_4060|M.avium_104                LRSGNRVTLDAQRFAQLGSWSGRIVIDGQEIAVDPATWIGSRDRSWGIRP
Mb3194|M.bovis_AF2122/97            LRSGNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIRP
Rv3169|M.tuberculosis_H37Rv         LRSGNRVTLDAQRFAQLGTWSGRIVVDGERIAVDPATWLGSRDRSWGIRP
Mflv_4498|M.gilvum_PYR-GCK          MRRGTRVTLNAQRFAQVGSWSGQLSIDGTDIAVDPAQWIGTRDRSWGIRP
Mvan_1868|M.vanbaalenii_PYR-1       MRRGNRVTLDAQRFAQVGTWSGLLSIDGEDIAVDPARWIGTRDRSWGIRP
MAB_4483|M.abscessus_ATCC_1997      QRQLGRVMFDTSRFAQTGTWTGQLTIDGTTHELDGVNWSGNRDRSWGIRP
TH_0414|M.thermoresistible__bu      FRDRGRVDEDARRFYQVGRASGGITVGDRRIDID-DSWHFGRDHSWGVRR
MSMEG_4982|M.smegmatis_MC2_155      HRSRGRVSEDARRFYQNGQVEGWIEIDGERIEIDPGSWWFGRDHSWGIRN
                                     *   **  :: ** * *   * : :..    :*   *   **:***:* 

MMAR_1392|M.marinum_M               VGEP----EPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRSL
MUL_2484|M.ulcerans_Agy99           VGEP----EPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEEPSGFRSL
MAV_4060|M.avium_104                IGEP----EPAGRPADPPFEGMWWLYVPMAFDDFAIVLIIQEQPDGFRSL
Mb3194|M.bovis_AF2122/97            VGEP----EPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRSL
Rv3169|M.tuberculosis_H37Rv         VGEP----EPAGRPADPPFEGMWWLYVPLAFDDFAVVLIIQEEPDGFRSL
Mflv_4498|M.gilvum_PYR-GCK          IGEA----EPAGRPDDPPFEGMWWLYIPMAFDDFGIVIIIQEDPLGFRSL
Mvan_1868|M.vanbaalenii_PYR-1       VGEA----EPAGRPDDPPFEGMWWLYVPMAFDDFGIVIIIQEDPQGFRSL
MAB_4483|M.abscessus_ATCC_1997      VGEG----EPAGRRAT-LAGGFFWLYNVISFPQYSIVFINQEDEHGNKVV
TH_0414|M.thermoresistible__bu      GGGGGDLPETSILQPRTIPDGVLYFMGIFEFDDRLVHFAQRETADGEVFH
MSMEG_4982|M.smegmatis_MC2_155      GPGGGSLSEGAHLQPQEIPDGTLYYMGIFQFDDELVHFAQRETSTGERWQ
                                            * :         *  :    : * :  : :  :*   *    

MMAR_1392|M.marinum_M               NDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPVH
MUL_2484|M.ulcerans_Agy99           NDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDATRPDGTPVH
MAV_4060|M.avium_104                NDCTRIWRDGR---VEQLGWPRVKIHYRSGTRIPTGATIDASAPDGTPVH
Mb3194|M.bovis_AF2122/97            NDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPVH
Rv3169|M.tuberculosis_H37Rv         NDCTRIWRDGH---VEQLGWPRVRIHYRSGTRIPTGATIEASTPDGAPVH
Mflv_4498|M.gilvum_PYR-GCK          NDCTRVWKDGR---VEQLGWPRVKIQYRSGTRIPTGATVEATALDGSPLH
Mvan_1868|M.vanbaalenii_PYR-1       NDCTRIWKDGR---VEQLGWPRVKIHYRSGTRIPTGATIEATAFDGSPLR
MAB_4483|M.abscessus_ATCC_1997      SGARRVWRDPSKG-IEELGPIAHDITLIPGTREARSAVVTLG-----DIT
TH_0414|M.thermoresistible__bu      YEGEMLAPSSTGRPSTPITRVSHDFTFRDDLRVISGGKVTIHTADGSAED
MSMEG_4982|M.smegmatis_MC2_155      FEGEVLYPIETGRPAGTIIDVEHDLKFRDDLRVISGGTFTVHRGDRTTST
                                         :           :      :    . *   .. .           

MMAR_1392|M.marinum_M               FDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIARS
MUL_2484|M.ulcerans_Agy99           FDVESKLAVPIHVGGGYGGDSDWLHGMWKGEKFVERLTYGMTDPAIIARS
MAV_4060|M.avium_104                FDVESKLPVPIHVGGGYGGDSDWLHGMWKGEKFTERLTYDMTDPAIIARS
Mb3194|M.bovis_AF2122/97            FDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIARA
Rv3169|M.tuberculosis_H37Rv         FDVESKLAVPTHVGGGYGGDSDWSHGMWKGEKFVERRTYDMTDPTIIARA
Mflv_4498|M.gilvum_PYR-GCK          FDVESKLAVPIHVGGGYGGDSDWLHGVWKGPNFTERLTYDMTDPAVIGRA
Mvan_1868|M.vanbaalenii_PYR-1       FEVESKLPVPIHVGGGYGGDSDWLHGVWKGEGFTERLTYDMTDPAIVGRA
MAB_4483|M.abscessus_ATCC_1997      ITADIVLPHYFGFGTGYGLDPDWRHGMWQGDLVVQGKRYKTAELDATLKL
TH_0414|M.thermoresistible__bu      ITITPLTGFWPGFAG-YDEYRGYASGHWRGPSYVDSFVVDTTDPAEVG--
MSMEG_4982|M.smegmatis_MC2_155      IEVRPMTDFWPGLAG-YMEVDGYASGHWRGRDFIDGFTADIGDIDVVK--
                                    :           ..  *    .:  * *:*    :       :       

MMAR_1392|M.marinum_M               GFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP--
MUL_2484|M.ulcerans_Agy99           GFGVIDHVGRAVCRDGDTDPVEGWGLYEHGALGRHDPSGFSDWLTVAP--
MAV_4060|M.avium_104                GFGVIDHVGRAICRDGDKAPVEGWGLYEHGALGRHDPSGFSDWLTVAP--
Mb3194|M.bovis_AF2122/97            GFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP--
Rv3169|M.tuberculosis_H37Rv         GFGVIDHVGRALCRDGDGNPVQGWGLFEHGALGRHDPSGFADWSTLAP--
Mflv_4498|M.gilvum_PYR-GCK          GFGVIDHVGRAVCREADGTEREGWGLFEHGALGRHDPSGFADWLTVAP--
Mvan_1868|M.vanbaalenii_PYR-1       GFGVIDHVGRAVCRDADGTEREGWGLFEHGALGRHDPSGFADWLTVAP--
MAB_4483|M.abscessus_ATCC_1997      LCPVDNLATFRLIENG--VETHGSGLFEFGPIGPHKPSGFTGFVDTHQER
TH_0414|M.thermoresistible__bu      QVSLLSETFCRVRC----GDAVGHGLVEMVFVGRNERYGYAGY-------
MSMEG_4982|M.smegmatis_MC2_155      PVSFLSETLCEVSMDSGSGPKIGHGLVEMVFVGAYPRYGYTGW-------
                                       . . .   :          * ** *   :*     *::.:       

MMAR_1392|M.marinum_M               ----
MUL_2484|M.ulcerans_Agy99           ----
MAV_4060|M.avium_104                ----
Mb3194|M.bovis_AF2122/97            ----
Rv3169|M.tuberculosis_H37Rv         ----
Mflv_4498|M.gilvum_PYR-GCK          ----
Mvan_1868|M.vanbaalenii_PYR-1       ----
MAB_4483|M.abscessus_ATCC_1997      DSDS
TH_0414|M.thermoresistible__bu      ----
MSMEG_4982|M.smegmatis_MC2_155      ----