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LARQVARSLVVAVVTAWALSLTTVAAPVAGAASCPDVEVVFARGTSDTKGFGSVGRAFIDSLKWKLLGKK VSAYAVDYPASWNFSKSTSAGAVDANKHVQYVAGMCPDTKIVLGGMSQGAGVIDLITIGNRKIWFFTPAP LPDAMVNHVVAVAVFANPSRDYSYLGPLTDISPQYGHKTIDLCVDGDPYCSSGVNMFAHWSYPWNGMVNE AATFVAQRVLGQDT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3344 | - | - | 100% (225) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_3105 | - | 2e-58 | 52.07% (217) | cutinase |
| M. vanbaalenii PYR-1 | Mvan_0371 | - | 1e-47 | 50.76% (197) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2006c | cfp21 | 4e-46 | 45.25% (221) | cutinase precursor CFP21 |
| M. gilvum PYR-GCK | Mflv_3552 | - | 3e-92 | 77.51% (209) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 4e-46 | 45.25% (221) | cutinase precursor CFP21 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3809c | - | 6e-35 | 39.56% (225) | cutinase Cut4 |
| M. marinum M | MMAR_3837 | - | 6e-52 | 49.13% (230) | cutinase precursor |
| M. avium 104 | MAV_1682 | - | 4e-44 | 46.48% (213) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_1528 | - | 7e-44 | 47.25% (218) | cutinase |
| M. thermoresistible (build 8) | TH_4127 | - | 2e-40 | 45.32% (203) | PUTATIVE serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_0855 | cut4 | 7e-41 | 45.66% (219) | cutinase precursor, Cut4 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3344|M.vanbaalenii_PYR-1 -------------------MLARQVARSLVVAVVTA-WALSLTTVAAPVA
Mflv_3552|M.gilvum_PYR-GCK --------------------------------MVTG-WALSLSIASAPVA
Mb2006c|M.bovis_AF2122/97 -------------------MTPRSLVRIVGVVVATT-LALVSAPAGGRAA
Rv1984c|M.tuberculosis_H37Rv -------------------MTPRSLVRIVGVVVATT-LALVSAPAGGRAA
MMAR_3837|M.marinum_M -------------MCQHQNVNARQSTRLLGVGLATICAALLSAPLIIASA
MAV_1682|M.avium_104 ---------------------------MLGAGAMTAGATLLGAPLP---A
TH_4127|M.thermoresistible__bu --------------------------------VLGS--AALLAGVPAPTA
MSMEG_1528|M.smegmatis_MC2_155 ---MSLDLVFR------RARLVA-AAALIATVMLAAPLAAHAPTGALGAA
MUL_0855|M.ulcerans_Agy99 MWLFPLDAQKWARSGRGRTRLARRCAGLVATTIAACAVLLAFP---LVPK
MAB_3809c|M.abscessus_ATCC_199 ----------------MNRYVKRGSVGVSIFAVSAAAAVLANPSENSAIA
.
Mvan_3344|M.vanbaalenii_PYR-1 GAASCPDVEVVFARGTSDTKGFGSVGRAFIDSLKWKLLGKKVSAYAVDYP
Mflv_3552|M.gilvum_PYR-GCK VAASCPDVEVVFARGTADKPGVGFTGRQFVTALKKRLPGKTVSVYAVNYP
Mb2006c|M.bovis_AF2122/97 HADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYP
Rv1984c|M.tuberculosis_H37Rv HADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYP
MMAR_3837|M.marinum_M SAAACPDAEVTFARGTAEPPGVGGVGQAFIDSLRSQLGGRSLGVYAVNYP
MAV_1682|M.avium_104 SAAPCPDIEVTFARGTAEPPGVGGVGQAFVEALRSQAGARSLGVYPVNYP
TH_4127|M.thermoresistible__bu AAIPCSDVEVVFARGTSEPPGVGRVGQALANALQARLPGRTVSTYGVSYP
MSMEG_1528|M.smegmatis_MC2_155 RAADCPDIEVVFARGTDESPGIGRIGNAFVQALRGKVGGRSVGTYAVNYP
MUL_0855|M.ulcerans_Agy99 AAAACPDVQVVFARGTGEPPGLGRVGNAMVASLRQKT-DQSIGAYAVNYP
MAB_3809c|M.abscessus_ATCC_199 AAAGCPDVDVSFARGTNDSPGLGDVGKAFTDELTDRLAGKSVDIYAVNYP
* *.* * ***** : *.* *. : * : :.:. * *.**
Mvan_3344|M.vanbaalenii_PYR-1 ASWNFSKSTSAGAVDANKHVQYVAGMCPDTKIVLGGMSQGAGVIDLIT--
Mflv_3552|M.gilvum_PYR-GCK ASWNFSKSTSEGAVDANKHVQYVAAVCPRTKIVLGGMSQGAGVIDLIT--
Mb2006c|M.bovis_AF2122/97 ASDDYRASASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLST--
Rv1984c|M.tuberculosis_H37Rv ASDDYRASASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLST--
MMAR_3837|M.marinum_M ATEDWPPSASAGATDASTHVESMAASCPNTKLVLGGYSQGAMVIDLIT--
MAV_1682|M.avium_104 ADDDFAASASAGAGDASAHVQSMVADCPNTKLVLGGYSQGAMVIDLIT--
TH_4127|M.thermoresistible__bu ATYDFLAAT-DGANDATARITTLAQQCPSTRVVLGGYSQGAAVVDMLGGL
MSMEG_1528|M.smegmatis_MC2_155 ASYDFLAAA-DGANDASGHVQWMVNNCPNTRLVLGGYSQGAAVIDVIA--
MUL_0855|M.ulcerans_Agy99 ANKDFLAAA-DGANDASDHVQQMTNECPNTKLVLGGYSQGAAVINIVT--
MAB_3809c|M.abscessus_ATCC_199 ASFDWVRAG-DGANDMSYHVQEVARNCPNTQFVLGGFSQGAAVVDVLFG-
* :: : *: * . :: . ** *:.**** **** *:::
Mvan_3344|M.vanbaalenii_PYR-1 IGNRKIWFFTPAPLPDAMVNHVVAVAVFANPSR---DYSYLG-PLTDISP
Mflv_3552|M.gilvum_PYR-GCK VGNRIIWFFKPAPLPDKMVNHVAAIAVFGNPSR---DISSLG-PLTKISP
Mb2006c|M.bovis_AF2122/97 SAMPPAV-----------ADHVAAVALFGEPSSGFSSMLWGGGSLPTIGP
Rv1984c|M.tuberculosis_H37Rv SAMPPAV-----------ADHVAAVALFGEPSSGFSSMLWGGGSLPTIGP
MMAR_3837|M.marinum_M IARAPVAGFIPQTLSAEVADHVAAVAVFGNPTD-----RYLGGPISEISP
MAV_1682|M.avium_104 IAQAPVAGLIPQTLNADQAEHVSALALFGNPSD-----RYLGAPVSVVSP
TH_4127|M.thermoresistible__bu PPLGDRVGLVGSALPTGSVGNVAAVAVFGNPSA------KFGRPINT-SP
MSMEG_1528|M.smegmatis_MC2_155 AVPFPAIGFN-APLPANVPEHVAAVAVFGNPSA------KLG-LPLTASP
MUL_0855|M.ulcerans_Agy99 AAPLPGLGFT-QPLPAQAAQHVAAVTLFGNPSG------RAGGLMTALSP
MAB_3809c|M.abscessus_ATCC_199 -TNGTGLTFN-NPLPTDLEKRVAAIVLIGNPKN-----WQVAGMNLDLSI
.* *:.::.:*. . .
Mvan_3344|M.vanbaalenii_PYR-1 QYG--HKTIDLCVDGDPYCSSGVNMFA----------HWSYPWNGMVNEA
Mflv_3552|M.gilvum_PYR-GCK LYG--SKAIDLCATGDPYCSSGNNFFA----------HFAYPWNGMVNEA
Mb2006c|M.bovis_AF2122/97 LYS--SKTINLCAPDDPICTGGGNIMA----------HVSYVQSGMTSQA
Rv1984c|M.tuberculosis_H37Rv LYS--SKTINLCAPDDPICTGGGNIMA----------HVSYVQSGMTSQA
MMAR_3837|M.marinum_M WYG--HKAIDLCAPNDPICTPG-ALALPSHDEMFSAAHLSYAQSGMPSQA
MAV_1682|M.avium_104 WYG--AKAIDLCAPGDPVCTPGGPLALPSHDEMVSPAHLSYRQSGMPAQA
TH_4127|M.thermoresistible__bu VFG--GRGIDLCSDGDPICSNGRNPFA----------HTNYETSVHIETA
MSMEG_1528|M.smegmatis_MC2_155 VYG--SRAIDLCNAGDPVCGSGDSVPA----------HRAYD-GGPANQA
MUL_0855|M.ulcerans_Agy99 HFG--GKILNLCNTGDPICSDGDQWKA----------HTGYV-PGLTNKA
MAB_3809c|M.abscessus_ATCC_199 RDDQRSKIIDICNPGDGICDPNGGGLG---------PHMQYKSDGSADKA
. : :::* .* * . * * *
Mvan_3344|M.vanbaalenii_PYR-1 ATFVAQRVLGQDT-------------------------------------
Mflv_3552|M.gilvum_PYR-GCK ATFAAGRVLGTQN-------------------------------------
Mb2006c|M.bovis_AF2122/97 ATFAANRLDHAG--------------------------------------
Rv1984c|M.tuberculosis_H37Rv ATFAANRLDHAG--------------------------------------
MMAR_3837|M.marinum_M ATFVVSQL------------------------------------------
MAV_1682|M.avium_104 ATFVAAHL------------------------------------------
TH_4127|M.thermoresistible__bu ADFAAGLI------------------------------------------
MSMEG_1528|M.smegmatis_MC2_155 AAFVAGLL------------------------------------------
MUL_0855|M.ulcerans_Agy99 ASFVAGRI------------------------------------------
MAB_3809c|M.abscessus_ATCC_199 ADFVAGRLAAVAASSSAAAASSSTSTTASGVPASTSKSANPLSATTAPAP
* *.. :
Mvan_3344|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3552|M.gilvum_PYR-GCK --------------------------------------------------
Mb2006c|M.bovis_AF2122/97 --------------------------------------------------
Rv1984c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3837|M.marinum_M --------------------------------------------------
MAV_1682|M.avium_104 --------------------------------------------------
TH_4127|M.thermoresistible__bu --------------------------------------------------
MSMEG_1528|M.smegmatis_MC2_155 --------------------------------------------------
MUL_0855|M.ulcerans_Agy99 --------------------------------------------------
MAB_3809c|M.abscessus_ATCC_199 TSASPAPASSPSSSTPKPVAASTSRRVPAWMMPATDAPAAEVPAAVTSTI
Mvan_3344|M.vanbaalenii_PYR-1 -----------------
Mflv_3552|M.gilvum_PYR-GCK -----------------
Mb2006c|M.bovis_AF2122/97 -----------------
Rv1984c|M.tuberculosis_H37Rv -----------------
MMAR_3837|M.marinum_M -----------------
MAV_1682|M.avium_104 -----------------
TH_4127|M.thermoresistible__bu -----------------
MSMEG_1528|M.smegmatis_MC2_155 -----------------
MUL_0855|M.ulcerans_Agy99 -----------------
MAB_3809c|M.abscessus_ATCC_199 PAPDPARHGPLPGPGGQ