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MMSSSMDELLPPVPAPVIDIRDLAVVRGGRVALDGVSVQVARGTITGLLGPSGCGKTTLMRCIVGTQIVA GGSVLVLGHPAGSAQLRHRVGYVTQDPTIYPDLPVVDNVRYFAALSGTDRQDVDDAIEAVGLHGYRKARA GNLSGGQKTRVSLACALVARPDLLVLDEPTVGLDPVLRADLWDRFDRLARDGTTLLVSSHVMDEADRCED LVLLRAGKILAHTTPARLREDTGCQSLEHAFLAIIRRGTAKSTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3296 | - | - | 100% (254) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3091 | - | 7e-33 | 40.00% (230) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4796 | - | 2e-30 | 37.38% (214) | daunorubicin resistance ABC transporter ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1713c | - | 4e-98 | 70.87% (254) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_2197 | - | 1e-32 | 34.38% (224) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1687c | - | 4e-98 | 70.87% (254) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 6e-30 | 33.78% (222) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3698 | - | 6e-31 | 36.79% (212) | ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2486 | - | 4e-88 | 64.82% (253) | antibiotic resistance ABC transporter, efflux system, |
| M. avium 104 | MAV_3085 | - | 1e-97 | 72.91% (251) | ABC transporter ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_3762 | - | 3e-98 | 72.22% (252) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3667 | - | 9e-31 | 36.55% (238) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_1666 | - | 4e-87 | 63.78% (254) | antibiotic resistance ABC transporter, efflux system, |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 MTGREAPTLTVVFDGDERKFAPGHDIHIGRDIHADVRITHPLVSRIHLII
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 RFVDGKWIAEDQRSLNGIFVNGRQVGWVEVRDDTVINLGDPGGPRLTFAL
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 GGLGGETQLGIAPPTMRGYVSGAQQQAPYTGAQQHGTTGQPYHSTQQHYP
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 TGGYQSGPQTYGQPPSQQHPYGAAPSGPQTYGTSGPTRPRQQYPSEPTPV
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 -----------------------------------------------MMI
Rv1687c|M.tuberculosis_H37Rv -----------------------------------------------MMI
MMAR_2486|M.marinum_M ------------------------------------------------MT
MUL_1666|M.ulcerans_Agy99 -----------------------------------------------MVT
MAV_3085|M.avium_104 ------------------------------------------------MM
Mvan_3296|M.vanbaalenii_PYR-1 -----------------------------------------------MMS
MSMEG_3762|M.smegmatis_MC2_155 -----------------------------------------------MMT
MAB_3698|M.abscessus_ATCC_1997 PASYSNEPVEPFGTRAMRALGIGGAPKPTPGAITVGRAPDNTIVVNDVLA
MLBr_00590|M.leprae_Br4923 ------------------------------------------------MS
TH_3667|M.thermoresistible__bu -------------------------------------------VIKTMKT
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 SSSDEL--LRDGADPAVIIDQLR---------------------------
Rv1687c|M.tuberculosis_H37Rv SSSDEL--LRDGADPAVIIDQLR---------------------------
MMAR_2486|M.marinum_M STSVES--LTGGSQPAVSIKHLR---------------------------
MUL_1666|M.ulcerans_Agy99 STSVES--VTGGSQPAVSIKHLR---------------------------
MAV_3085|M.avium_104 SSSGDE--LIGGAEPAVRIEHLR---------------------------
Mvan_3296|M.vanbaalenii_PYR-1 SSMDEL--LPPVPAPVIDIRDLA---------------------------
MSMEG_3762|M.smegmatis_MC2_155 SSRDELSATPSEREPAIEIDGLH---------------------------
MAB_3698|M.abscessus_ATCC_1997 SRHHALLLPTPGGLEIQDLHTINGTFVNGVQVEQSSLREGDTVTIGNVDL
MLBr_00590|M.leprae_Br4923 SACTVP----ETPEVVIRLRGVC---------------------------
TH_3667|M.thermoresistible__bu KPADTSGAGPAVSNPAVSNPDVSAPQLRGADVEVQG--------------
Mflv_2197|M.gilvum_PYR-GCK ---------MPDTSPVVEIRGLR---------------------------
:
Mb1713c|M.bovis_AF2122/97 --------------------------VIRGKRLALQDVSVRVACGTITGL
Rv1687c|M.tuberculosis_H37Rv --------------------------VIRGKRLALQDVSVRVACGTITGL
MMAR_2486|M.marinum_M --------------------------VIRGKHSALHDFSVDIARGTITGL
MUL_1666|M.ulcerans_Agy99 --------------------------VIRGKHSALHDFSVDIARGTITGL
MAV_3085|M.avium_104 --------------------------VVRGKRPALHDFSVQIAKGSITGL
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------VVRGGRVALDGVSVQVARGTITGL
MSMEG_3762|M.smegmatis_MC2_155 --------------------------VVRGGRPAVRDVTVRIARGTITGL
MAB_3698|M.abscessus_ATCC_1997 VVQDGTLVKPTTATRVGGLEVQSIDFVVEGGKKLLDDISFSAGPGSLTAV
MLBr_00590|M.leprae_Br4923 --------------------------KHYGSILAVSNLDLDIHSAEVLAL
TH_3667|M.thermoresistible__bu ------------------------LHKSFGAKAVLRGVDLTVSAGTLTAV
Mflv_2197|M.gilvum_PYR-GCK --------------------------KAFGRTQALDGLDLAVAPGDVTGF
* : .. . . : ..
Mb1713c|M.bovis_AF2122/97 LGPSGSGKTTLIRCIVGSQIIASGSVSVLGQ--PAGSAEL---RHRVGYM
Rv1687c|M.tuberculosis_H37Rv LGPSGSGKTTLIRCIVGSQIIASGSVSVLGQ--PAGSAEL---RHRVGYM
MMAR_2486|M.marinum_M LGPSGCGKTTLMRSIVGTQIVTSGTVTVLGH--PAGSAVL---RRQVGYL
MUL_1666|M.ulcerans_Agy99 LGPSGCGKTTLMRSIVGTQIVTSGTVTVLGH--PAGSAVL---RRQVGYL
MAV_3085|M.avium_104 LGPSGCGKTTLIRCIVGTQILTKGSVTVLGK--PAGSAEL---RHRVGYL
Mvan_3296|M.vanbaalenii_PYR-1 LGPSGCGKTTLMRCIVGTQIVAGGSVLVLGH--PAGSAQL---RHRVGYV
MSMEG_3762|M.smegmatis_MC2_155 LGPSGCGKTTLMRCIVGTQIVAKGTVTVLGH--PAGSAPL---RHRVGYV
MAB_3698|M.abscessus_ATCC_1997 IGPSGAGKSTLARLIVGNTQPSAGKVSFEGHGVHAEYAVM---RNRIGMV
MLBr_00590|M.leprae_Br4923 LGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARL---RARIGVM
TH_3667|M.thermoresistible__bu LGPSGCGKTTLLRILAGFDDPDAGTVRIGGHTLAGGGAPVPAHRRRVGLM
Mflv_2197|M.gilvum_PYR-GCK LGPNGAGKSTAIRVLLGLLRADGGDVRLLGADPWRDAVAL---HRRIAYV
:**.*.**:* . * * : . * . : : ::. :
Mb1713c|M.bovis_AF2122/97 PQDPTIYNDLRVIDNIRYFAELCG-------VDRQAADEVIEAVDLRDHR
Rv1687c|M.tuberculosis_H37Rv PQDPTIYNDLRVIDNIRYFAELCG-------VDRQAADEVIEAVDLRDHR
MMAR_2486|M.marinum_M PQDPAIYHDLRIIDNVRYFAALYG-------YNRQAADDAIARVGLTDHR
MUL_1666|M.ulcerans_Agy99 PQDPAIYHDLRIIDNVRYFAALYG-------YNRQAADDAIARVGLTDHR
MAV_3085|M.avium_104 PQDPTIYNDLRVVDNVRYFAALYG-------FDGQAADAAIDRVGLTDHR
Mvan_3296|M.vanbaalenii_PYR-1 TQDPTIYPDLPVVDNVRYFAALSG-------TDRQDVDDAIEAVGLHGYR
MSMEG_3762|M.smegmatis_MC2_155 TQNPTIYDDLRVIDNVRYFAALYG-------TSPAAADQAVDAVGLGDQR
MAB_3698|M.abscessus_ATCC_1997 PQDDVVHPQLTVSQALHYAAELRLPPDTTKEDREQVVSRVLEELEMTKHA
MLBr_00590|M.leprae_Br4923 LQGGGGYPAARAGEMLNLVASYAA--------DPLDPEWLLETLGLTDVA
TH_3667|M.thermoresistible__bu PQEGALFPHLSVAENIAFGLRRTR-----RAGRADTVRYWLEVVGLEGAA
Mflv_2197|M.gilvum_PYR-GCK PGDVTLWPNLTGMQAIDFLTALRG-----DGVDTRRRDELIERFELDPHK
: : : . :
Mb1713c|M.bovis_AF2122/97 TARCANLSGGQRARVSLACALVGRPDLLVLDEPTIGLDPVLRVELWDRFT
Rv1687c|M.tuberculosis_H37Rv TARCANLSGGQRARVSLACALVGRPDLLVLDEPTIGLDPVLRVELWDRFT
MMAR_2486|M.marinum_M TDYCANLSGGQRTRVSLACALVCHPTLLVLDEPTVGLDPVLRVDLWQQFA
MUL_1666|M.ulcerans_Agy99 TDYCANLSGGQRTRVSLACALVCHPTLLVPDEPTVGLDPVLRVDLWQQFA
MAV_3085|M.avium_104 IALCGNLSGGQRTRVSLACALVRRPDLLVLDEPTVGLDPVLRADLWDQFA
Mvan_3296|M.vanbaalenii_PYR-1 KARAGNLSGGQKTRVSLACALVARPDLLVLDEPTVGLDPVLRADLWDRFD
MSMEG_3762|M.smegmatis_MC2_155 SAYCGNLSGGQRTRASLACALVAEPELLVLDEPTVGLDPVLRVDLWQQFN
MAB_3698|M.abscessus_ATCC_1997 ETRVDKLSGGQRKRASVAMELLTGPSLLILDEPTSGLDPALDRQVMSLMR
MLBr_00590|M.leprae_Br4923 RTTYRRLSGGQQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELID
TH_3667|M.thermoresistible__bu EARPHELSGGQQQRVALARALAAEPRVLLLDEPFVALDAGLRVRVREEIA
Mflv_2197|M.gilvum_PYR-GCK KAR--TYSKGNRQKVAIVAAFSTRSELFILDEPTSGLDPLMEKTFQECVR
* *:: : ::. : . :.. *** .:*. . . .
Mb1713c|M.bovis_AF2122/97 ALARRG-TTLLVSSHVMDEADRCGD-LLLLRQGQLLAHTTPHR-LRKETG
Rv1687c|M.tuberculosis_H37Rv ALARRG-TTLLVSSHVMDEADRCGD-LLLLRQGQLLAHTTPHR-LRKETG
MMAR_2486|M.marinum_M ELARAR-TTLLISSHVMDEAEHCGD-LLLMRAGRLVAQTTPTQ-LRKDTG
MUL_1666|M.ulcerans_Agy99 ELARAR-TTLLISSHVMNEAEHCGD-LLLMRAGRLVAQTTPTQ-LRKDTG
MAV_3085|M.avium_104 ALARGG-TTLLVSSHVMDEADHCGD-LLLMREGRLVAHTTPNR-LREDTG
Mvan_3296|M.vanbaalenii_PYR-1 RLARDG-TTLLVSSHVMDEADRCED-LVLLRAGKILAHTTPAR-LREDTG
MSMEG_3762|M.smegmatis_MC2_155 DLAAKG-TTLVVSSHVMDEADHCGD-LLLMREGRLLAHTTPAR-LREDTS
MAB_3698|M.abscessus_ATCC_1997 QLADAG-RVVVVVTHSLTYLSYCDQ-VLLLAPGGKTAYCGPPRSIGQEMG
MLBr_00590|M.leprae_Br4923 TLRRDG-VTVVLTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAK
TH_3667|M.thermoresistible__bu AILRAAGTTAVLVTHDQSEALSLADSVALLMDGRLAQVGAPADIYERPAT
Mflv_2197|M.gilvum_PYR-GCK EVAGRG-AAVLLSSHILAEVEKLCDSVTIVRSGRTVRSGTLAQMRQFMRT
: . :: :* : : :: *
Mb1713c|M.bovis_AF2122/97 CTSLEEAFLSIVRRTTTVPAAG----------------------------
Rv1687c|M.tuberculosis_H37Rv CTSLEEAFLSIVRRTTTVPAAG----------------------------
MMAR_2486|M.marinum_M CMSLEEAFLSMIRRHTTTHQAE----------------------------
MUL_1666|M.ulcerans_Agy99 CMSLEEAFLSMIRRHTTTHQAE----------------------------
MAV_3085|M.avium_104 CTSLEDAFLSIIKRSTMREAG-----------------------------
Mvan_3296|M.vanbaalenii_PYR-1 CQSLEHAFLAIIRRGTAKSTA-----------------------------
MSMEG_3762|M.smegmatis_MC2_155 CSSLEQAFLAVIRQYAAAA-------------------------------
MAB_3698|M.abscessus_ATCC_1997 TTDWADIFANAAADPDGVHQAYLSRHPAANKPATAASPPGDLGKPPKTSL
MLBr_00590|M.leprae_Br4923 DQLRFSAPPRLDLSLLAFALPEDYKTTELTPG------EYLVAGPIDPQV
TH_3667|M.thermoresistible__bu PAAARFVGATVELPGQARDGVVHTALGSHPARLPVPDGPVVVVLRPEELR
Mflv_2197|M.gilvum_PYR-GCK TVTVRVRGDGRALVDAPYVHDLRTDDGALRFSVDRDHLDRAVLDLTALGI
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 LRQVSTVARRQGRLILADRGYFIFLALLPFVLAGLVLSVPGSAGFNVALP
MLBr_00590|M.leprae_Br4923 LATVTAWCAQINVLTTNMRVEQHSLEDVFLDLTGRKLR------------
TH_3667|M.thermoresistible__bu LERSRDGVPAAAVQSVRFYGPQSAVQVRLADDTVVTVLTAGDAGVSVGEP
Mflv_2197|M.gilvum_PYR-GCK EDLAVAPASLEDMFLQEYQGANR---------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 DNPNEPGLLLALTNLGASFLGLALTIRDLIGERVIFRREQAVGLSATAYL
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu VGVRVDGSVLAYPAPGRPPARS----------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 LAKIITYCGAAIVQSAIMTAVIVIVRGGPTQGAVLLGSANFELWVAVAAT
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 ACAATVLGLVLSSLATSAEQVMPMLVIATMTQIVFSGGLIPVTGRAGLEQ
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3698|M.abscessus_ATCC_1997 LSFLFPSRWGFAATAATCDLRKLVPVGPQDELWNHDAGTWLFDMGILGLL
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
TH_3667|M.thermoresistible__bu --------------------------------------------------
Mflv_2197|M.gilvum_PYR-GCK --------------------------------------------------
Mb1713c|M.bovis_AF2122/97 ----------------
Rv1687c|M.tuberculosis_H37Rv ----------------
MMAR_2486|M.marinum_M ----------------
MUL_1666|M.ulcerans_Agy99 ----------------
MAV_3085|M.avium_104 ----------------
Mvan_3296|M.vanbaalenii_PYR-1 ----------------
MSMEG_3762|M.smegmatis_MC2_155 ----------------
MAB_3698|M.abscessus_ATCC_1997 SLVMAGFVRWRIRLKG
MLBr_00590|M.leprae_Br4923 ----------------
TH_3667|M.thermoresistible__bu ----------------
Mflv_2197|M.gilvum_PYR-GCK ----------------