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MMTSSRDELSATPSEREPAIEIDGLHVVRGGRPAVRDVTVRIARGTITGLLGPSGCGKTTLMRCIVGTQI VAKGTVTVLGHPAGSAPLRHRVGYVTQNPTIYDDLRVIDNVRYFAALYGTSPAAADQAVDAVGLGDQRSA YCGNLSGGQRTRASLACALVAEPELLVLDEPTVGLDPVLRVDLWQQFNDLAAKGTTLVVSSHVMDEADHC GDLLLMREGRLLAHTTPARLREDTSCSSLEQAFLAVIRQYAAAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3762 | - | - | 100% (254) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6509 | - | 4e-35 | 38.98% (254) | ABC-type drug export system, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6766 | - | 7e-35 | 39.53% (215) | ABC transporter, ATP-binding protein, NodI family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1713c | - | 3e-95 | 67.87% (249) | ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_1936 | - | 1e-30 | 35.37% (229) | daunorubicin resistance ABC transporter ATPase subunit |
| M. tuberculosis H37Rv | Rv1687c | - | 3e-95 | 67.87% (249) | ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 2e-27 | 33.94% (221) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1858 | - | 8e-31 | 36.14% (202) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2486 | - | 1e-94 | 72.22% (234) | antibiotic resistance ABC transporter, efflux system, |
| M. avium 104 | MAV_3085 | - | 1e-103 | 74.30% (249) | ABC transporter ATP-binding subunit |
| M. thermoresistible (build 8) | TH_3667 | - | 8e-32 | 38.91% (239) | PUTATIVE ferric cations import ATP-binding protein FbpC |
| M. ulcerans Agy99 | MUL_1666 | - | 1e-93 | 68.40% (250) | antibiotic resistance ABC transporter, efflux system, |
| M. vanbaalenii PYR-1 | Mvan_3296 | - | 3e-98 | 72.22% (252) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1713c|M.bovis_AF2122/97 ---MMISSSDELLRDGAD------------------PAVIIDQLRVIRGK
Rv1687c|M.tuberculosis_H37Rv ---MMISSSDELLRDGAD------------------PAVIIDQLRVIRGK
MMAR_2486|M.marinum_M ----MTSTSVESLTGGSQ------------------PAVSIKHLRVIRGK
MUL_1666|M.ulcerans_Agy99 ---MVTSTSVESVTGGSQ------------------PAVSIKHLRVIRGK
MAV_3085|M.avium_104 ----MMSSSGDELIGGAE------------------PAVRIEHLRVVRGK
Mvan_3296|M.vanbaalenii_PYR-1 ---MMSSSMDELLPPVPA------------------PVIDIRDLAVVRGG
MSMEG_3762|M.smegmatis_MC2_155 ---MMTSSRDELSATPSERE----------------PAIEIDGLHVVRGG
TH_3667|M.thermoresistible__bu VIKTMKTKPADTSGAGPAVSNPAVSNPDVSAPQLRGADVEVQGLHKSFGA
Mflv_1936|M.gilvum_PYR-GCK ------------MPFP--------------------PAIEALDLVKRFGD
MAB_1858|M.abscessus_ATCC_1997 ------------MTEV--------------------IQVRELTFTYPKTP
MLBr_00590|M.leprae_Br4923 ----MSSACTVPETPE--------------------VVIRLRGVCKHYGS
: .
Mb1713c|M.bovis_AF2122/97 RLALQDVSVRVACGTITGLLGPSGSGKTTLIRCIVGSQIIASGSVSVLGQ
Rv1687c|M.tuberculosis_H37Rv RLALQDVSVRVACGTITGLLGPSGSGKTTLIRCIVGSQIIASGSVSVLGQ
MMAR_2486|M.marinum_M HSALHDFSVDIARGTITGLLGPSGCGKTTLMRSIVGTQIVTSGTVTVLGH
MUL_1666|M.ulcerans_Agy99 HSALHDFSVDIARGTITGLLGPSGCGKTTLMRSIVGTQIVTSGTVTVLGH
MAV_3085|M.avium_104 RPALHDFSVQIAKGSITGLLGPSGCGKTTLIRCIVGTQILTKGSVTVLGK
Mvan_3296|M.vanbaalenii_PYR-1 RVALDGVSVQVARGTITGLLGPSGCGKTTLMRCIVGTQIVAGGSVLVLGH
MSMEG_3762|M.smegmatis_MC2_155 RPAVRDVTVRIARGTITGLLGPSGCGKTTLMRCIVGTQIVAKGTVTVLGH
TH_3667|M.thermoresistible__bu KAVLRGVDLTVSAGTLTAVLGPSGCGKTTLLRILAGFDDPDAGTVRIGGH
Mflv_1936|M.gilvum_PYR-GCK QTAVAGVSFVVPPGTVLGLLGPNGAGKTTTVRMMTTLTEPTSGTARVAGF
MAB_1858|M.abscessus_ATCC_1997 EPAVRGMDFTVGEGEIFGFLGPSGAGKSTTQKLLIGLLRGHGGRATVWGR
MLBr_00590|M.leprae_Br4923 ILAVSNLDLDIHSAEVLALLGPNGAGKTTTVEMCEGFVRPDAGTIEVLGL
.: .. . : . : ..***.*.**:* . * : *
Mb1713c|M.bovis_AF2122/97 PAG-----SAELRHRVGYMPQDPTIYNDLRVIDNIRYFAELCGVD--RQA
Rv1687c|M.tuberculosis_H37Rv PAG-----SAELRHRVGYMPQDPTIYNDLRVIDNIRYFAELCGVD--RQA
MMAR_2486|M.marinum_M PAG-----SAVLRRQVGYLPQDPAIYHDLRIIDNVRYFAALYGYN--RQA
MUL_1666|M.ulcerans_Agy99 PAG-----SAVLRRQVGYLPQDPAIYHDLRIIDNVRYFAALYGYN--RQA
MAV_3085|M.avium_104 PAG-----SAELRHRVGYLPQDPTIYNDLRVVDNVRYFAALYGFD--GQA
Mvan_3296|M.vanbaalenii_PYR-1 PAG-----SAQLRHRVGYVTQDPTIYPDLPVVDNVRYFAALSGTD--RQD
MSMEG_3762|M.smegmatis_MC2_155 PAG-----SAPLRHRVGYVTQNPTIYDDLRVIDNVRYFAALYGTS--PAA
TH_3667|M.thermoresistible__bu TLAGGGAPVPAHRRRVGLMPQEGALFPHLSVAENIAFGLRRTRRAGRADT
Mflv_1936|M.gilvum_PYR-GCK DVR---THPDEVRRHMGLTGQVATVDELLTGRENIRMIGGLYGIRR-RDL
MAB_1858|M.abscessus_ATCC_1997 EPG---AWGRNYYQRIGVSFELPNHYQKLTALENLRFFASLYAGPT-RDP
MLBr_00590|M.leprae_Br4923 DPI---TDNARLRARIGVMLQGGGGYPAARAGEMLNLVAS-YAADP-LDP
::* : : :
Mb1713c|M.bovis_AF2122/97 AD---EVIEAVDLRDHRTARCANLSGGQRARVSLACALVGRPDLLVLDEP
Rv1687c|M.tuberculosis_H37Rv AD---EVIEAVDLRDHRTARCANLSGGQRARVSLACALVGRPDLLVLDEP
MMAR_2486|M.marinum_M AD---DAIARVGLTDHRTDYCANLSGGQRTRVSLACALVCHPTLLVLDEP
MUL_1666|M.ulcerans_Agy99 AD---DAIARVGLTDHRTDYCANLSGGQRTRVSLACALVCHPTLLVPDEP
MAV_3085|M.avium_104 AD---AAIDRVGLTDHRIALCGNLSGGQRTRVSLACALVRRPDLLVLDEP
Mvan_3296|M.vanbaalenii_PYR-1 VD---DAIEAVGLHGYRKARAGNLSGGQKTRVSLACALVARPDLLVLDEP
MSMEG_3762|M.smegmatis_MC2_155 AD---QAVDAVGLGDQRSAYCGNLSGGQRTRASLACALVAEPELLVLDEP
TH_3667|M.thermoresistible__bu VR---YWLEVVGLEGAAEARPHELSGGQQQRVALARALAAEPRVLLLDEP
Mflv_1936|M.gilvum_PYR-GCK KNLGDQLLHQFSLTDAADRPVRSYSGGMRRRLDLAVSLLASPPVLFLDEP
MAB_1858|M.abscessus_ATCC_1997 ----MELLDAVGLADDANTRVGAFSKGMQMRLTFVRALINDPELLFLDEP
MLBr_00590|M.leprae_Br4923 ----EWLLETLGLTDVARTTYRRLSGGQQQRLALACTLVGRPELVFLDEP
: ..* . * * : * :. :* * ::. ***
Mb1713c|M.bovis_AF2122/97 TIGLDPVLRVELWDRFTALARRG--TTLLVSSHVMDEADRCGDLLLLRQG
Rv1687c|M.tuberculosis_H37Rv TIGLDPVLRVELWDRFTALARRG--TTLLVSSHVMDEADRCGDLLLLRQG
MMAR_2486|M.marinum_M TVGLDPVLRVDLWQQFAELARAR--TTLLISSHVMDEAEHCGDLLLMRAG
MUL_1666|M.ulcerans_Agy99 TVGLDPVLRVDLWQQFAELARAR--TTLLISSHVMNEAEHCGDLLLMRAG
MAV_3085|M.avium_104 TVGLDPVLRADLWDQFAALARGG--TTLLVSSHVMDEADHCGDLLLMREG
Mvan_3296|M.vanbaalenii_PYR-1 TVGLDPVLRADLWDRFDRLARDG--TTLLVSSHVMDEADRCEDLVLLRAG
MSMEG_3762|M.smegmatis_MC2_155 TVGLDPVLRVDLWQQFNDLAAKG--TTLVVSSHVMDEADHCGDLLLMREG
TH_3667|M.thermoresistible__bu FVALDAGLRVRVREEIAAILRAAGTTAVLVTHDQSEALSLADSVALLMDG
Mflv_1936|M.gilvum_PYR-GCK TTGLDPRSRSELWDVLRGLVAQG-TTLLLTTQYLEEADQLADNIVVIDRG
MAB_1858|M.abscessus_ATCC_1997 TSGLDPVNARKVKDMVLELKARG-RTIFITTHAMSAADELCDRVAFVVDG
MLBr_00590|M.leprae_Br4923 TAGMDTHARLLVWELIDTLRRDG-VTVVLTTHQLKEAEELADRLVIIDHG
.:*. : : . : * .: : . . : .: *
Mb1713c|M.bovis_AF2122/97 QLLAHTTPHRLRKETGCTSLEEAFLSIVRRTTTVPAAG------------
Rv1687c|M.tuberculosis_H37Rv QLLAHTTPHRLRKETGCTSLEEAFLSIVRRTTTVPAAG------------
MMAR_2486|M.marinum_M RLVAQTTPTQLRKDTGCMSLEEAFLSMIRRHTTTHQAE------------
MUL_1666|M.ulcerans_Agy99 RLVAQTTPTQLRKDTGCMSLEEAFLSMIRRHTTTHQAE------------
MAV_3085|M.avium_104 RLVAHTTPNRLREDTGCTSLEDAFLSIIKRSTMREAG-------------
Mvan_3296|M.vanbaalenii_PYR-1 KILAHTTPARLREDTGCQSLEHAFLAIIRRGTAKSTA-------------
MSMEG_3762|M.smegmatis_MC2_155 RLLAHTTPARLREDTSCSSLEQAFLAVIRQYAAAA---------------
TH_3667|M.thermoresistible__bu RLAQVGAPADIYERPATPAAARFVGATVELPGQARDGVVHTALGSHPARL
Mflv_1936|M.gilvum_PYR-GCK RIIAEGSPLHLKQQAGRASLVVTVADAADLESARGLLARTGAEVYVDAGA
MAB_1858|M.abscessus_ATCC_1997 RIVAMNSPAELKLEYGRRSVRVEYRGAAGELAG-----------------
MLBr_00590|M.leprae_Br4923 RMIAAGTPTELMHTGAKDQLRFSAPPRLDLSLLAFALPEDYKTTELTPGE
:: :* : .
Mb1713c|M.bovis_AF2122/97 --------------------------------------------------
Rv1687c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2486|M.marinum_M --------------------------------------------------
MUL_1666|M.ulcerans_Agy99 --------------------------------------------------
MAV_3085|M.avium_104 --------------------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 --------------------------------------------------
TH_3667|M.thermoresistible__bu PVPDGPVVVVLRPEELRLERSRDGVPAAAVQSVRFYGPQSAVQVRLADDT
Mflv_1936|M.gilvum_PYR-GCK RRLTATADGLDDMVKVAGWLRDSGITVDDIGLSRPSLDDVFLMLTGHRTD
MAB_1858|M.abscessus_ATCC_1997 --QDFPLDGLADNDAFHAVLR--GHHVETIHSEEASLDDVFVAVTGRRLA
MLBr_00590|M.leprae_Br4923 YLVAGPID-PQVLATVTAWCAQINVLTTNMRVEQHSLEDVFLDLTGRKLR
Mb1713c|M.bovis_AF2122/97 ---------------------------------------
Rv1687c|M.tuberculosis_H37Rv ---------------------------------------
MMAR_2486|M.marinum_M ---------------------------------------
MUL_1666|M.ulcerans_Agy99 ---------------------------------------
MAV_3085|M.avium_104 ---------------------------------------
Mvan_3296|M.vanbaalenii_PYR-1 ---------------------------------------
MSMEG_3762|M.smegmatis_MC2_155 ---------------------------------------
TH_3667|M.thermoresistible__bu VVTVLTAGDAGVSVGEPVGVRVDGSVLAYPAPGRPPARS
Mflv_1936|M.gilvum_PYR-GCK DTEEVGA--------------------------------
MAB_1858|M.abscessus_ATCC_1997 ---------------------------------------
MLBr_00590|M.leprae_Br4923 ---------------------------------------