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THATRDRAVDVARLAALVVVMFGHCALLLATIDGSGVRIGNLIGQVPAVAPVTWIVQVMPLFFLAGGAAG AYGHRAGTPWGAWLFTRAQRLYRPVFWYLAAWSVGLLAAWAALGADSAAGLGGESVALLWFLGVYVVTLA FVPALVRMRTGRAAAVVIAFLVAAAAAMDAVRLNTGTPAVAVGNFLFVWLIPVALGVAYARRLIGRHVAL AVAVAAFAVQTVLVAAGPYEVSLVVTGTEQISNVSPPTLLLAMHCLWMSCLFVAAAGAIGRWAQRPRVWT VVAAGNAGAMTLYLWHIVAIAIAAFGLHALGVDAYDVTASGFWGLLALRALVFSVVMFALFRLLAPLERH PLPWWDAPATAAGARATAAGALLCASAVVLVVMAKFGLGDGTGWSALAVFLGLAAAARTCAAAPAAVSGP QAPTEVGSRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3210 | - | - | 100% (432) | hypothetical protein Mvan_3210 |
| M. vanbaalenii PYR-1 | Mvan_4565 | - | 1e-82 | 42.26% (407) | hypothetical protein Mvan_4565 |
| M. vanbaalenii PYR-1 | Mvan_3490 | - | 2e-36 | 30.73% (423) | hypothetical protein Mvan_3490 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1705 | - | 5e-07 | 30.48% (187) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3453 | - | 1e-170 | 69.39% (428) | hypothetical protein Mflv_3453 |
| M. tuberculosis H37Rv | Rv1678 | - | 5e-07 | 30.48% (187) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1297c | - | 3e-87 | 43.34% (413) | hypothetical protein MAB_1297c |
| M. marinum M | MMAR_2582 | - | 1e-153 | 64.34% (429) | hypothetical protein MMAR_2582 |
| M. avium 104 | MAV_4113 | - | 2e-82 | 42.29% (428) | hypothetical protein MAV_4113 |
| M. smegmatis MC2 155 | MSMEG_3709 | - | 1e-160 | 67.15% (411) | hypothetical protein MSMEG_3709 |
| M. thermoresistible (build 8) | TH_0209 | - | 9e-54 | 46.72% (259) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3178 | - | 1e-150 | 63.40% (429) | hypothetical protein MUL_3178 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3210|M.vanbaalenii_PYR-1 ----------------MTHATRDRAVDVARLAALVVVMFGHCALLLATID
Mflv_3453|M.gilvum_PYR-GCK ----------------MTQSTRDRAVDVIRLAALVVVMFGHCALLLATID
MSMEG_3709|M.smegmatis_MC2_155 MPTPEAVPTRASDVDRATRPDRDRAVDVARLAALVAVMFGHCALLLATID
MMAR_2582|M.marinum_M -MRKTSLTPDPAALARSTPPGRDRAVDVARLCALVVVMFGHCALLLATID
MUL_3178|M.ulcerans_Agy99 -MRKTSLTPDPAALARSTPPGRVRAVDVARLWALVVVMFGHRALLLATID
TH_0209|M.thermoresistible__bu --------------------------------------------LPATID
MAB_1297c|M.abscessus_ATCC_199 -MTMTLGLPTADEVGAATPATRDRALDVIRIVSLAGVVLGHTIMAVSTID
MAV_4113|M.avium_104 -----MRFPDAAEVAARTPADRDRVLDVIRIVSLGGVVLGHTVMAASIIR
Mb1705|M.bovis_AF2122/97 --MARVRRGTELLLSPQSPPATGGLIVLTGLRLLAGLIWLYNVVWKVPPD
Rv1678|M.tuberculosis_H37Rv --MARVRRGTELLLSPQSPPATGGLIVLTGLRLLAGLIWLYNVVWKVPPD
Mvan_3210|M.vanbaalenii_PYR-1 GSG------VRIGNLIGQVPAVAPVTWIVQVMPLFFLAGGAAGAYGHR--
Mflv_3453|M.gilvum_PYR-GCK SGG------VRIANLIGEVPAVAPATWVVQVMPLFFLAGGAAGVHSYH--
MSMEG_3709|M.smegmatis_MC2_155 STG------VRVGNILGALPALAPITWILQVMPLFFLAGGAAGTYSRH--
MMAR_2582|M.marinum_M SHG------VRIGNLLGELPALTPLTWLVQVMPLFFLAGGAAGAYGWHPT
MUL_3178|M.ulcerans_Agy99 SHG------VRIGNLLGELPALTPLTWLVQVMPLFFMAGGAAGAYGWHPT
TH_0209|M.thermoresistible__bu RGG------VRIANILGALPALAPVTWAVQVMPLFFLAGGAAGAYGWCAA
MAB_1297c|M.abscessus_ATCC_199 NGV------LLWGNLLNGRPVFQALTWVFQIMPLFFFAGVAASVGSWK--
MAV_4113|M.avium_104 DHV------LIWDNLLTTSALFQAMTWLLQIMPLFFFAGAAACVSSWT--
Mb1705|M.bovis_AF2122/97 FGERGRRDLYHFTHLAVEHPVFTPFSWVIEHAVLPYFT------------
Rv1678|M.tuberculosis_H37Rv FGERGRRDLYHFTHLAVEHPVFTPFSWVIEHAVLPYFT------------
:: . . . :* .: * :::
Mvan_3210|M.vanbaalenii_PYR-1 ----AGTPWGAWLFTRAQRLYRPVFWYLAAWSVGLLAAWAALGADSAAGL
Mflv_3453|M.gilvum_PYR-GCK ----TGTPWGAWLFRRAQRLCRPVFWYLAVWAAVLAAARVVLGADSAVRL
MSMEG_3709|M.smegmatis_MC2_155 ----AGTPWGTWLFTRAQRLCRPVFAYLAAWVVALVAVHLTLGADSTAAL
MMAR_2582|M.marinum_M ---EPAVPWGAWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGL
MUL_3178|M.ulcerans_Agy99 ---EPAVPWGAWLLTRAQRLCRPVFWYLAAWTGALVVVRATLGAQSAAGL
TH_0209|M.thermoresistible__bu NRRDQAPTWGGWLMVRAQRLCRPLFCYLGMWAVALLTLRLTVGGADADRI
MAB_1297c|M.abscessus_ATCC_199 ----PGTSWGSWLMHRCTRLYRPVFYYLGFWAVALLILRQILPLHVYEPV
MAV_4113|M.avium_104 ----PGTDWGGWLMRRCTRLFRPVFYYLAFWAVTLTVLYQALPQHIYEPI
Mb1705|M.bovis_AF2122/97 -----AFGWGVLFAESALAVLLLTGTAVRLAALIGIGQSVAIGLSVAESP
Rv1678|M.tuberculosis_H37Rv -----AFGWGVLFAESALAVLLLTGTAVRLAALIGIGQSVAIGLSVAESP
. ** : . : : :
Mvan_3210|M.vanbaalenii_PYR-1 GGESVALLWFLGVYVVTLAFVPALVRMRTGRAAAVVIAFLVAAAAAMDAV
Mflv_3453|M.gilvum_PYR-GCK GGESVALLWFLGVYLVALAFVPALVRLRSGRAVAGVLAALLVVAASTDAL
MSMEG_3709|M.smegmatis_MC2_155 GRECVALLWFLGVYLVVLAFVPALTRMSSGRAVGALVTALVALAAVFDGL
MMAR_2582|M.marinum_M GRECVALLWFLGVYLVVLAFVPALTRLRTGYGIAAVSVTLLVLAAAVDQI
MUL_3178|M.ulcerans_Agy99 GRECVALLWFLGVYLVVLAFVPALTRVRTGYGIATVSVTLLVLAAAVDQI
TH_0209|M.thermoresistible__bu GREVVALLWFLGVYLIVPALVPAMTRLRT---------------------
MAB_1297c|M.abscessus_ATCC_199 AGVSTQLLWFLGAYVLVLAAIPLLARITTTRAMFTALAAVYLGIAAIDVL
MAV_4113|M.avium_104 AGVSTQLLWFLGAYVLVLAAMPVLYRITTTGRLAAGVAAVYGAIALIDVI
Mb1705|M.bovis_AF2122/97 GEWPWAYAMLLGIHVVLLFTCSTRYAAVDAVRAAATG-------------
Rv1678|M.tuberculosis_H37Rv GEWPWAYAMLLGIHVVLLFTCSTRYAAVDAVRAAATG-------------
. :** ::: .
Mvan_3210|M.vanbaalenii_PYR-1 RLNTGTPAVAVGNFLFVWLIPVALGVAYARRLIGRHVALAVAVAAFAVQT
Mflv_3453|M.gilvum_PYR-GCK RFATGDEAAGLTNFVIVWLIPVVIGVGYAQRLIGRRAAAVGAAAAFTTAW
MSMEG_3709|M.smegmatis_MC2_155 RFAVGTPAAGTANLVVVWLIPVVIGVAYARRLIRPRIALAVAVCTLAGQI
MMAR_2582|M.marinum_M RFAVGTAESGAANFLIVWLIPVALGVGYARRLIGPRAALVAAVAAFAAQL
MUL_3178|M.ulcerans_Agy99 RLAVGTAESGAANFLIVWLIPVALGVGYARRLIGPRAALVAAVDAFAAQL
TH_0209|M.thermoresistible__bu -----------------------------------AAAPMVLVVAFCGQL
MAB_1297c|M.abscessus_ATCC_199 RLGLDAPKGIGYVNFVVWLLPAVLGVGYRRQLITQRAALVLAATVFAINV
MAV_4113|M.avium_104 RLHWPALMPLGYLNLAVWLIPAMFGAAYRRGLLGGRAALAVAAAFFAADV
Mb1705|M.bovis_AF2122/97 -----------------------------------SAARTAAQRLLAGWG
Rv1678|M.tuberculosis_H37Rv -----------------------------------SAARTAAQRLLAGWG
* :
Mvan_3210|M.vanbaalenii_PYR-1 VLVAAGPYEVSLVVTGTEQISNVSPPTLLLAMHCLWMSCLFVAAAGAIGR
Mflv_3453|M.gilvum_PYR-GCK ALVVFGPYEVSLVVTGAERISNVSPPTLLLAMHCVWMSCVFVVAAAAIGR
MSMEG_3709|M.smegmatis_MC2_155 MLALVGPYDVSLVVTGAERVSNVSPPTMLLALHCTWVSCLFVACARAVGR
MMAR_2582|M.marinum_M RLAGTGVYDVSLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRR
MUL_3178|M.ulcerans_Agy99 RLVGTGVYDVSLVVTGADRMSNVAPPTLLLALHCTWMSCAFVAAAAVIRR
TH_0209|M.thermoresistible__bu ILAATGRYEVALVVTGIERVSNVSPPTLVLALQCTWMSCAFVVAAPAVRR
MAB_1297c|M.abscessus_ATCC_199 ALVTFGPYTISLVGVAGQKVPNMIPPSLVLAGHAIILSALASAAMPAINR
MAV_4113|M.avium_104 ALVRWGPYQLSMVGTGDHHLSNTSPPSLLLAGHAIILSALAIAAAPAIAR
Mb1705|M.bovis_AF2122/97 IVLGLIGLVAVWRGLGDDRPAYVGIRALEFSLGEYNLRGALALIAIALAM
Rv1678|M.tuberculosis_H37Rv IVLGLIGLVAVWRGLGDDRPAYVGIRALEFSLGEYNLRGALALIAIALAM
: . .: . :: :: : .:
Mvan_3210|M.vanbaalenii_PYR-1 WAQRPRVWTVVAAGNAGAMTLYLWHIVAIAIAAFGLHALGVDAYDVTASG
Mflv_3453|M.gilvum_PYR-GCK WARRPRVWRVVAAGNAGAMTLYLWHIVAIAIAAFGLHAVGLQAYDVAAPD
MSMEG_3709|M.smegmatis_MC2_155 WAHRPRVWHVVAVGNGGAMTLYLWHIPVIAAAALGLHALGLDAFDPHAPE
MMAR_2582|M.marinum_M WAARPRVWQLVAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPW
MUL_3178|M.ulcerans_Agy99 WAGRPRVWQLVAMGNGGAMTLYLWHIPAIAVAAFVLHAVGLDAFDVHTPW
TH_0209|M.thermoresistible__bu LAERP---------------------------------------------
MAB_1297c|M.abscessus_ATCC_199 WAQRPRVWWAVAIGNSGAMTLYLWHMPALLGMHLAFDFLGFDRYDTTAPD
MAV_4113|M.avium_104 WAQRPRVWWWTAIGNSGAMTLYLWHMPVLLGVHLAFDYLGCPRFPG-APD
Mb1705|M.bovis_AF2122/97 LAAAKRGWRTVAL-------------------------------------
Rv1678|M.tuberculosis_H37Rv LAAAKRGWRTVAL-------------------------------------
*
Mvan_3210|M.vanbaalenii_PYR-1 FWGLLALRALVFSVVMFALFRLLAPLERHPLPWWDAP-ATAAGARATAAG
Mflv_3453|M.gilvum_PYR-GCK LWAQLLVRTLVFAVVMLILFRLLSPLERRPLPWWDGA-VTESGPRAIGAG
MSMEG_3709|M.smegmatis_MC2_155 FWGLLALRAVVFAVLMAIAFRLLSPIEHRPLPWWDDQ-VQATGARSIVAG
MMAR_2582|M.marinum_M FWCLLALRAVVFTLVMAATFWLLSPLEHRRLPWWDEP-VRVVGARASAAG
MUL_3178|M.ulcerans_Agy99 FWCLLALRAVVFTLVMAATFWLLSPLEHRRLPWWDEP-VPVVGTRASASG
TH_0209|M.thermoresistible__bu ---------------------------------WTG--------------
MAB_1297c|M.abscessus_ATCC_199 FIALSVLQVATMMLLVTGLFLALRPLENNPLPGWDGGYIARPGARSAAAG
MAV_4113|M.avium_104 FLAISVAQVLLVVVAVAVLFVALRPLENNPLSGWDGAPAVMSRGWGAAVG
Mb1705|M.bovis_AF2122/97 ----------------------------------------------VAAV
Rv1678|M.tuberculosis_H37Rv ----------------------------------------------VAAV
Mvan_3210|M.vanbaalenii_PYR-1 ALLCASAVVLVVMAKFGLGDGTGWSALAVFLGLAAAARTCAAAPAAVSGP
Mflv_3453|M.gilvum_PYR-GCK ALVCAAGVALVLTAKFGLGESAGWAACAGFVAAVVAARFCARVAPHDLGP
MSMEG_3709|M.smegmatis_MC2_155 ALICVAGAVLTLMAKNGLDGVVGWSALAGFVASTAAARLCAGR----TGP
MMAR_2582|M.marinum_M LLVCGAGVALLLVAKNGLSGAPGWVSLGCFLVALVAARAMTGPPSG-AGE
MUL_3178|M.ulcerans_Agy99 LLVCGARVALLLVAKNGLSGAPGWVSLGCFLVALVAARAMTGPPSG-AGE
TH_0209|M.thermoresistible__bu ------RAVLLVLAKSGLGGAVGWTALGVFLATAAAARITAGSPTRPAAT
MAB_1297c|M.abscessus_ATCC_199 TALMLAGGFTLASVVWGLKGF-GLVCWVVVLAGLILARVLANRTKI----
MAV_4113|M.avium_104 ALLCVAGVALLAAIRWGLKDD-GLVCMAVVVAALVAARIVAQHAGPAGHG
Mb1705|M.bovis_AF2122/97 VAVAAAAAIYLQVGRTAVWLGGTNTTAAVFVCAAVVSLATEFRIGRVEGA
Rv1678|M.tuberculosis_H37Rv VAVAAAAAIYLQVGRTAVWLGGTNTTAAVFVCAAVVSLATEFRIGRVEGA
.: .: :
Mvan_3210|M.vanbaalenii_PYR-1 --QAPTEVGSRRP--------
Mflv_3453|M.gilvum_PYR-GCK DVRSPSESPENENLEHIASNS
MSMEG_3709|M.smegmatis_MC2_155 ---AGTGSAARG---------
MMAR_2582|M.marinum_M AERAPAAVRQRVG--------
MUL_3178|M.ulcerans_Agy99 AQRAPAAVRQRVG--------
TH_0209|M.thermoresistible__bu HPSAGDEAVGAIR--------
MAB_1297c|M.abscessus_ATCC_199 ---------------------
MAV_4113|M.avium_104 SSSRPCSMA------------
Mb1705|M.bovis_AF2122/97 ---------------------
Rv1678|M.tuberculosis_H37Rv ---------------------