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M. tuberculosis H37Rv Rv1678 (-)

annotation: PROBABLE INTEGRAL MEMBRANE PROTEIN
coordinates: 1902397 - 1903299
length: 300

MARVRRGTELLLSPQSPPATGGLIVLTGLRLLAGLIWLYNVVWKVPPDFGERGRRDLYHFTHLAVEHPVF
TPFSWVIEHAVLPYFTAFGWGVLFAESALAVLLLTGTAVRLAALIGIGQSVAIGLSVAESPGEWPWAYAM
LLGIHVVLLFTCSTRYAAVDAVRAAATGSAARTAAQRLLAGWGIVLGLIGLVAVWRGLGDDRPAYVGIRA
LEFSLGEYNLRGALALIAIALAMLAAAKRGWRTVALVAAVVAVAAAAAIYLQVGRTAVWLGGTNTTAAVF
VCAAVVSLATEFRIGRVEGA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1678--100% (300)PROBABLE INTEGRAL MEMBRANE PROTEIN
M. tuberculosis H37RvRv1999c-8e-0625.31% (162) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1705-1e-169100.00% (300) integral membrane protein
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2598-2e-0526.42% (159) hypothetical protein MAB_2598
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4851-7e-0534.12% (85) hypothetical protein MUL_4851
M. vanbaalenii PYR-1Mvan_5886-3e-8857.39% (291) hypothetical protein Mvan_5886

CLUSTAL 2.0.9 multiple sequence alignment


Rv1678|M.tuberculosis_H37Rv         -----------------------------------MARVRRGTELLLS--
Mb1705|M.bovis_AF2122/97            -----------------------------------MARVRRGTELLLS--
Mvan_5886|M.vanbaalenii_PYR-1       ---------------------------------MTTASPRRAIDLVLS--
MUL_4851|M.ulcerans_Agy99           ---------------------------------MDCEVARETLSARLD--
MAB_2598|M.abscessus_ATCC_1997      MSSQQPGALRRELGTFDAVMIGLGSMIGAGIFAALAPAARSAGSALLIGL
                                                                           *   .  *   

Rv1678|M.tuberculosis_H37Rv         -----------------PQSPPATGGLIVLTGLRLLAGLIWLYN---VVW
Mb1705|M.bovis_AF2122/97            -----------------PQSPPATGGLIVLTGLRLLAGLIWLYN---VVW
Mvan_5886|M.vanbaalenii_PYR-1       -----------------PAPAPARAGGISLTVLRIVAG-LWLAH---VWW
MUL_4851|M.ulcerans_Agy99           -----------------GEREPVPSARVDEHLDECGACGLWFEQ---VAG
MAB_2598|M.abscessus_ATCC_1997      CVAAVIAYCNATSSARLAAVYPASGGTYVYGRERLGDFWGYLAGWGFVVG
                                                         *. ..       .      ::     *  

Rv1678|M.tuberculosis_H37Rv         KVPPDFGERGRRDLYHFTHLAVEHPVFTPFSWVIEHAVLPYFTAFGWGVL
Mb1705|M.bovis_AF2122/97            KVPPDFGERGRRDLYHFTHLAVEHPVFTPFSWVIEHAVLPYFTAFGWGVL
Mvan_5886|M.vanbaalenii_PYR-1       KVPPDFGEARRTGLWFWTHLAVDHPVFPPYSWLVEHVVLPNFTPFGWLVL
MUL_4851|M.ulcerans_Agy99           QASRLQRLIESRPVIGAVDLAGIRPTPQPR-------ERKRMSWQRWALL
MAB_2598|M.abscessus_ATCC_1997      KTASCAAMALTIGFYAWPGHAHAVAVASVVALTAINYVGVQKSAWLTRVI
                                    :..          .      *   ..                :     ::

Rv1678|M.tuberculosis_H37Rv         FAESALAVLLLTGTAVR--------------------------LAALIGI
Mb1705|M.bovis_AF2122/97            FAESALAVLLLTGTAVR--------------------------LAALIGI
Mvan_5886|M.vanbaalenii_PYR-1       VVETLLPVLLLTGTAVR--------------------------LAALIGI
MUL_4851|M.ulcerans_Agy99           CVG---IAQVAVGIVQG--------------------------LGFSLGL
MAB_2598|M.abscessus_ATCC_1997      VAIVLSVLAAIVATAAGSGSVDIAALDLTGTSWRGVLQAAGLLFFAFAGY
                                     .         .. .                            :    * 

Rv1678|M.tuberculosis_H37Rv         GQSVAIGLSVAESPGEWPWAYAMLLGIHVVLLFTCSTRYAAVDAVRAAAT
Mb1705|M.bovis_AF2122/97            GQSVAIGLSVAESPGEWPWAYAMLLGIHVVLLFTCSTRYAAVDAVRAAAT
Mvan_5886|M.vanbaalenii_PYR-1       GQSLAIGMSVAQAPNEWPWAYAMMLGIHLVLLLAPSAQYAAVDAIRAARR
MUL_4851|M.ulcerans_Agy99           GHHYVIGSGNHLLNESTAWTIALGVAMVVAAIWPG---------------
MAB_2598|M.abscessus_ATCC_1997      ARIATLGEEVRDPARTIPRAIPIALGIALVVYVVVALAVLITLGPSRLAS
                                    .:  .:*          . : .: :.: :.                    

Rv1678|M.tuberculosis_H37Rv         GSAARTAAQRLLAG--WGIVLGLIGLVAVWRGLGD-------DRPAYVGI
Mb1705|M.bovis_AF2122/97            GSAARTAAQRLLAG--WGIVLGLIGLVAVWRGLGD-------DRPAYVGI
Mvan_5886|M.vanbaalenii_PYR-1       DGEPAPIARRLLGG--WGLLLALVAIVAAVKSLGDPFV---APRGSGVGY
MUL_4851|M.ulcerans_Agy99           ------AAEGLAGV--LMVFVAVLSVYVVVDALSG----------AVTTS
MAB_2598|M.abscessus_ATCC_1997      SAAPLLDAVTAAGAGWMEPVVRIGAVVAATGSLLALILGVSRTTFAMARD
                                           *    .      .: : .: ..  .*            : .  

Rv1678|M.tuberculosis_H37Rv         RALEFSLGEYN----------LRGALALIAIALAMLAAAKRGWRTVALVA
Mb1705|M.bovis_AF2122/97            RALEFSLGEYN----------LRGALALIAIALAMLAAAKRGWRTVALVA
Mvan_5886|M.vanbaalenii_PYR-1       PPLQLFLGDYN----------MLAALVLLIVAGLMLAAAAVRIRALAVTS
MUL_4851|M.ulcerans_Agy99           RVLTRVLTHLP----------VLLGTVLAVMVWRSRGAPRPAPDVLADEP
MAB_2598|M.abscessus_ATCC_1997      RHLPHTLATVHPKYGVPYRAEILVGLVVSVLAATADLRGAIGFSSFAVLV
                                      *   *              :  . .:  :.             .*   

Rv1678|M.tuberculosis_H37Rv         AVVAVAAAAAIYLQVGRTAVWLGGTNTTAAVFVCAAVVSLATEFRIGRVE
Mb1705|M.bovis_AF2122/97            AVVAVAAAAAIYLQVGRTAVWLGGTNTTAAVFVCAAVVSLATEFRIGRVE
Mvan_5886|M.vanbaalenii_PYR-1       AAIAALAALSIYVQLGRGEVWLGGNPSTAAVFVCAAVIAVG--ARPLRVS
MUL_4851|M.ulcerans_Agy99           DIVLPQNAS-----RGRRHGHLWPTDGSAA--------------------
MAB_2598|M.abscessus_ATCC_1997      YYAVANASAWTLTPSQGRPARIIPAVGLVGCVIVSLALPLSSVAAGTGVL
                                           :             :      ..                    

Rv1678|M.tuberculosis_H37Rv         GA-----------------
Mb1705|M.bovis_AF2122/97            GA-----------------
Mvan_5886|M.vanbaalenii_PYR-1       S------------------
MUL_4851|M.ulcerans_Agy99           -------------------
MAB_2598|M.abscessus_ATCC_1997      AVGVIVYALRRVSGPGRRE