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PFTRADVLSAAQQSLAAAGAHDRGGWIGLFTADARVEDPVGSAPHRGHVALGHFYDTFIGPRVITYRPDT DIVVGTTVIRDLELDIQMAPTLTMHVPTYIRYDLRADGDELKIAALSAYWELPAMIGQFARGGLGAVPAG IALGRSMVANQGLSGALGFLGGFRGLGAGGGTLFARFLDDACGGDEVGIRRLVSDAPVTAGDSEPMTSSD LVKQLAGGAWSKRVSSGRSVAARVEHDGRRSVLIGEIGGTGRAGAKIARIRLFGDIH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3185 | - | - | 100% (268) | nuclear transport factor 2 |
M. vanbaalenii PYR-1 | Mvan_5165 | - | 6e-05 | 37.10% (62) | nuclear transport factor 2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2068c | - | 4e-62 | 46.97% (264) | hypothetical protein Mb2068c |
M. gilvum PYR-GCK | Mflv_3431 | - | 1e-101 | 66.92% (266) | nuclear transport factor 2 |
M. tuberculosis H37Rv | Rv2042c | - | 4e-62 | 46.97% (264) | hypothetical protein Rv2042c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1289c | - | 1e-42 | 37.50% (264) | hypothetical protein MAB_1289c |
M. marinum M | MMAR_3015 | - | 3e-64 | 47.13% (261) | hypothetical protein MMAR_3015 |
M. avium 104 | MAV_2473 | - | 2e-62 | 45.45% (264) | steroid delta-isomerase |
M. smegmatis MC2 155 | MSMEG_3684 | - | 3e-64 | 46.81% (282) | steroid delta-isomerase |
M. thermoresistible (build 8) | TH_3530 | - | 2e-71 | 53.66% (246) | PUTATIVE putative nuclear transport factor 2 |
M. ulcerans Agy99 | MUL_4084 | - | 3e-06 | 28.12% (128) | ketosteroid isomerase- like protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2068c|M.bovis_AF2122/97 -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVG------ Rv2042c|M.tuberculosis_H37Rv -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVG------ MMAR_3015|M.marinum_M -MALPKRDDLLAAVERSPRAAAAHDRAGWVSLFTSDGRVEDPVG------ MAV_2473|M.avium_104 MVAPLDRQQLLAAVERSPQAAAEHDRAAWVALFTPDGRIEDPVG------ Mvan_3185|M.vanbaalenii_PYR-1 --MPFTRADVLSAAQQSLAAAGAHDRGGWIGLFTADARVEDPVG------ Mflv_3431|M.gilvum_PYR-GCK --MPFTRADVAAAAQRSLAAAAAHDRETWIGLFTADGRVEDPVG------ MSMEG_3684|M.smegmatis_MC2_155 --MGPTRAELLTAVERSPQAAAVHDRDAWVGLFADGGRIEDPVG------ TH_3530|M.thermoresistible__bu --MTFTRTEMIAVVERSPHTIEARDRHGWVDLFTPDARIEDPVG------ MAB_1289c|M.abscessus_ATCC_199 MSSAPFADELLATVQASPAAVGAHDKDTWVGLFATYGQVNDPVG------ MUL_4084|M.ulcerans_Agy99 ---MSSTHPAHEAGRRSREAVTARDKQAWLAVFADDAVVEDPIGPSAFDP . . * : :*: *: :*: . ::**:* Mb2068c|M.bovis_AF2122/97 -SQPQVGHEAIGRFYDTFIGPRD-ITFHR-DLDIVSGTVVLRDLELEVAM Rv2042c|M.tuberculosis_H37Rv -SQPQVGHEAIGRFYDTFIGPRD-ITFHR-DLDIVSGTVVLRDLELEVAM MMAR_3015|M.marinum_M -SMPHVGHEQIGRFFDTFIGPRD-IKFHR-DLDIVCGTVVLRDVELEVAM MAV_2473|M.avium_104 -SRPHLGRTQIGRFYDTFIAPRD-IRFHR-DLDVVFGTTVLRDLELEVAM Mvan_3185|M.vanbaalenii_PYR-1 -SAPHRGHVALGHFYDTFIGPRV-ITYRP-DTDIVVGTTVIRDLELDIQM Mflv_3431|M.gilvum_PYR-GCK -SAPHRGRAAIGRFYDTFIAPRT-ITAHVQGEDIVVDTTVLRDVELEIEM MSMEG_3684|M.smegmatis_MC2_155 -SRPHRGPAEIAQFYDTFIGPRD-IAFHR-DVDIVAGSTVIRDLELEVAM TH_3530|M.thermoresistible__bu -SRPHIGRDRIERFYDTFIGPRR-LRLHP-ETDLVVGTTVLRDLRLEVTM MAB_1289c|M.abscessus_ATCC_199 -SRPHIGESAIGKFYDTFIAPNT-IVFDV-ENDVVAGMSVLRDLTIHTTM MUL_4084|M.ulcerans_Agy99 EGKGHRGRAAISAFWDKAIEPTTRIEFFFRDTYQCGNEEANVGHILITTG . : * : *:*. * * : . . . : Mb2068c|M.bovis_AF2122/97 DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA Rv2042c|M.tuberculosis_H37Rv DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA MMAR_3015|M.marinum_M AAGVT--------MFVPAFLRYDLR------KASDEWKIAVLRAYWDLPA MAV_2473|M.avium_104 GPTVT--------MYIPAFLRYDLR------ETNGEWLIGALRAYWELPA Mvan_3185|M.vanbaalenii_PYR-1 APTLT--------MHVPTYIRYDLR------ADGDELKIAALSAYWELPA Mflv_3431|M.gilvum_PYR-GCK SAAVS--------LRVPTFIRYDLR------ADGDDLQVCALSAYWELPA MSMEG_3684|M.smegmatis_MC2_155 GAADPGTGNAAVTMRIPAYLRYALQDTETDTETGAGPRIAELQAYWELPA TH_3530|M.thermoresistible__bu AAGLP--------LDIPAFLRYDLA------ADGTELRIAALQAFWELPT MAB_1289c|M.abscessus_ATCC_199 STGVT--------MHIPMHLRYDVVED----GPASSLKIDRLFAYWELRA MUL_4084|M.ulcerans_Agy99 DYQVT----------AEGVFTYKAN---------DARQLVALRAYWEMDR . : * : * *:*:: Mb2068c|M.bovis_AF2122/97 MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH Rv2042c|M.tuberculosis_H37Rv MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH MMAR_3015|M.marinum_M MMLQFLRGGAQVAKPALMLSRGLLGNQGLRGTAGFMTGFRRSG----ARH MAV_2473|M.avium_104 MMVQFLRSGPGAARPAVDLCRGLLRNQGWRGSAGFMAGFRRVG----APH Mvan_3185|M.vanbaalenii_PYR-1 MIGQFARGGLGAVPAGIALGRSMVANQGLSGALGFLGGFRGLG----AGG Mflv_3431|M.gilvum_PYR-GCK MIGQFARAGLGVVPVGVSLGRSMFANQGIGGSVGFLRGFRGSG----SAG MSMEG_3684|M.smegmatis_MC2_155 MVFQFVRNGTRAVPVGLQLAGDLLRNQGPVGAVGFAAGFRGVGARPRSHG TH_3530|M.thermoresistible__bu MIGSFLRSGPRAVPAGLGLSRALLVNQGLSGAAGFLAGLRTLG----SHG MAB_1289c|M.abscessus_ATCC_199 MISQLLGSGGDGLLASAKLGPQLLKNQGLNGVLGFMRGLKGVH----AAG MUL_4084|M.ulcerans_Agy99 AAATTRKA------------------------------------------ Mb2068c|M.bovis_AF2122/97 KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS Rv2042c|M.tuberculosis_H37Rv KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS MMAR_3015|M.marinum_M QALVSTFLDGVVRGDSQAATRTLTDTATITLGDDDVLELAELIEQLRRAT MAV_2473|M.avium_104 QRLVRRFLDAVAAGDKFAAAQALSSTAAITLGDRDPIELAELAEQLAGAG Mvan_3185|M.vanbaalenii_PYR-1 GTLFARFLDDACGGDEVGIRR-LVSDAPVTAGDSEPMTSSDLVKQLAGGA Mflv_3431|M.gilvum_PYR-GCK KRVFARFLDDACGGDEVGMRR-LLSDAPVTLGDGDPLTSSDVVGYLSGGT MSMEG_3684|M.smegmatis_MC2_155 RRRFIRLLDDLCAGDEVSVRRTLRRDARVQSGESAPLGASKLTAMTAGGS TH_3530|M.thermoresistible__bu RKGFGGFLADAATGDEVAVRRRLARGARITLGDDEPMTATALLTRLAGTR MAB_1289c|M.abscessus_ATCC_199 KQRVQELTAALAARDIPTVTTVLAPEAALSLDGVSEASLAEFASAASSLT MUL_4084|M.ulcerans_Agy99 -------------------------------------------------- Mb2068c|M.bovis_AF2122/97 WTKVTGAGSTVAVSLASDHRRGIMFADVPW----RGNRINRIRYFPA--- Rv2042c|M.tuberculosis_H37Rv WTKVTGAGSTVAVSLASDHRRGIMFADVPW----RGNRINRIRYFPA--- MMAR_3015|M.marinum_M WSKMIGSGSTVTVSVVTDHGRGIMFAELPW----RGNEIHRVRYFPS--- MAV_2473|M.avium_104 LTKMNSAGPAVAVSLHSGHGRAIMFADVAW----RANAINRIRYFPA--- Mvan_3185|M.vanbaalenii_PYR-1 WSKRVSSGRSVAARVEHDGRRSVLIGEIGG-TGRAGAKIARIRLFGDIH- Mflv_3431|M.gilvum_PYR-GCK WSKLIASGDAVAARVDTDGHHRILLADTAGGLTRERPTITRVRLFA---- MSMEG_3684|M.smegmatis_MC2_155 WRKVIVSGASAVAGIDSEAGRAVLIADLTP------TRIRRVRYFVDDAA TH_3530|M.thermoresistible__bu ASKVICAGGAVVARIERAGRRDIVIAHADP----RPLTINRIRYFTEQPQ MAB_1289c|M.abscessus_ATCC_199 VDKLLAAGPSVSATVHLGNRRGIGLFEFSD-NSAAPGTLASVRLYF---- MUL_4084|M.ulcerans_Agy99 -------------------------------------------------- Mb2068c|M.bovis_AF2122/97 --- Rv2042c|M.tuberculosis_H37Rv --- MMAR_3015|M.marinum_M --- MAV_2473|M.avium_104 --- Mvan_3185|M.vanbaalenii_PYR-1 --- Mflv_3431|M.gilvum_PYR-GCK --- MSMEG_3684|M.smegmatis_MC2_155 RDG TH_3530|M.thermoresistible__bu G-- MAB_1289c|M.abscessus_ATCC_199 --- MUL_4084|M.ulcerans_Agy99 ---