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ALPKRDDLLAAVERSPRAAAAHDRAGWVSLFTSDGRVEDPVGSMPHVGHEQIGRFFDTFIGPRDIKFHRD LDIVCGTVVLRDVELEVAMAAGVTMFVPAFLRYDLRKASDEWKIAVLRAYWDLPAMMLQFLRGGAQVAKP ALMLSRGLLGNQGLRGTAGFMTGFRRSGARHQALVSTFLDGVVRGDSQAATRTLTDTATITLGDDDVLEL AELIEQLRRATWSKMIGSGSTVTVSVVTDHGRGIMFAELPWRGNEIHRVRYFPS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3015 | - | - | 100% (265) | hypothetical protein MMAR_3015 |
| M. marinum M | MMAR_5010 | - | 3e-06 | 29.69% (128) | ketosteroid isomerase- like protein |
| M. marinum M | MMAR_4937 | - | 3e-06 | 28.57% (133) | hypothetical protein MMAR_4937 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2068c | - | 1e-110 | 70.57% (265) | hypothetical protein Mb2068c |
| M. gilvum PYR-GCK | Mflv_3431 | - | 2e-61 | 48.29% (263) | nuclear transport factor 2 |
| M. tuberculosis H37Rv | Rv2042c | - | 1e-110 | 70.57% (265) | hypothetical protein Rv2042c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1289c | - | 6e-42 | 38.93% (244) | hypothetical protein MAB_1289c |
| M. avium 104 | MAV_2473 | - | 2e-96 | 65.77% (260) | steroid delta-isomerase |
| M. smegmatis MC2 155 | MSMEG_3684 | - | 3e-59 | 44.96% (278) | steroid delta-isomerase |
| M. thermoresistible (build 8) | TH_3530 | - | 1e-61 | 46.90% (258) | PUTATIVE putative nuclear transport factor 2 |
| M. ulcerans Agy99 | MUL_0468 | - | 2e-06 | 28.57% (133) | hypothetical protein MUL_0468 |
| M. vanbaalenii PYR-1 | Mvan_3185 | - | 3e-64 | 47.13% (261) | nuclear transport factor 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2068c|M.bovis_AF2122/97 -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVGSQPQ--
Rv2042c|M.tuberculosis_H37Rv -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVGSQPQ--
MMAR_3015|M.marinum_M -MALPKRDDLLAAVERSPRAAAAHDRAGWVSLFTSDGRVEDPVGSMPH--
MAV_2473|M.avium_104 MVAPLDRQQLLAAVERSPQAAAEHDRAAWVALFTPDGRIEDPVGSRPH--
MSMEG_3684|M.smegmatis_MC2_155 --MGPTRAELLTAVERSPQAAAVHDRDAWVGLFADGGRIEDPVGSRPH--
TH_3530|M.thermoresistible__bu --MTFTRTEMIAVVERSPHTIEARDRHGWVDLFTPDARIEDPVGSRPH--
Mflv_3431|M.gilvum_PYR-GCK --MPFTRADVAAAAQRSLAAAAAHDRETWIGLFTADGRVEDPVGSAPH--
Mvan_3185|M.vanbaalenii_PYR-1 --MPFTRADVLSAAQQSLAAAGAHDRGGWIGLFTADARVEDPVGSAPH--
MAB_1289c|M.abscessus_ATCC_199 MSSAPFADELLATVQASPAAVGAHDKDTWVGLFATYGQVNDPVGSRPH--
MUL_0468|M.ulcerans_Agy99 -MTQTAQSPALAASQASWRCVQAHDRQGWLALMADDIVIEDPIGKSVTNP
:. : * :*: *: *:: ::**:*.
Mb2068c|M.bovis_AF2122/97 -----VGHEAIGRFYDTFIGPRDITFHR-DLDIVSG-TVVLRDLELEVAM
Rv2042c|M.tuberculosis_H37Rv -----VGHEAIGRFYDTFIGPRDITFHR-DLDIVSG-TVVLRDLELEVAM
MMAR_3015|M.marinum_M -----VGHEQIGRFFDTFIGPRDIKFHR-DLDIVCG-TVVLRDVELEVAM
MAV_2473|M.avium_104 -----LGRTQIGRFYDTFIAPRDIRFHR-DLDVVFG-TTVLRDLELEVAM
MSMEG_3684|M.smegmatis_MC2_155 -----RGPAEIAQFYDTFIGPRDIAFHR-DVDIVAG-STVIRDLELEVAM
TH_3530|M.thermoresistible__bu -----IGRDRIERFYDTFIGPRRLRLHP-ETDLVVG-TTVLRDLRLEVTM
Mflv_3431|M.gilvum_PYR-GCK -----RGRAAIGRFYDTFIAPRTITAHVQGEDIVVD-TTVLRDVELEIEM
Mvan_3185|M.vanbaalenii_PYR-1 -----RGHVALGHFYDTFIGPRVITYRP-DTDIVVG-TTVIRDLELDIQM
MAB_1289c|M.abscessus_ATCC_199 -----IGESAIGKFYDTFIAPNTIVFDV-ENDVVAG-MSVLRDLTIHTTM
MUL_0468|M.ulcerans_Agy99 DGTGVRGKDGVANFYDTNIAANQLSITCEETFPSSSPNEIAHILVLRSRF
* : .*:** *... : . : : : : :
Mb2068c|M.bovis_AF2122/97 DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA
Rv2042c|M.tuberculosis_H37Rv DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA
MMAR_3015|M.marinum_M AAGVT--------MFVPAFLRYDLR------KASDEWKIAVLRAYWDLPA
MAV_2473|M.avium_104 GPTVT--------MYIPAFLRYDLR------ETNGEWLIGALRAYWELPA
MSMEG_3684|M.smegmatis_MC2_155 GAADPGTGNAAVTMRIPAYLRYALQDTETDTETGAGPRIAELQAYWELPA
TH_3530|M.thermoresistible__bu AAGLP--------LDIPAFLRYDLA------ADGTELRIAALQAFWELPT
Mflv_3431|M.gilvum_PYR-GCK SAAVS--------LRVPTFIRYDLR------ADGDDLQVCALSAYWELPA
Mvan_3185|M.vanbaalenii_PYR-1 APTLT--------MHVPTYIRYDLR------ADGDELKIAALSAYWELPA
MAB_1289c|M.abscessus_ATCC_199 STGVT--------MHIPMHLRYDVVED----GPASSLKIDRLFAYWELRA
MUL_0468|M.ulcerans_Agy99 DGGFT--------SEVRGVFTYRVN---------DEGLMTNMRGYWNLEM
. : : * : : : .:*:*
Mb2068c|M.bovis_AF2122/97 MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH
Rv2042c|M.tuberculosis_H37Rv MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH
MMAR_3015|M.marinum_M MMLQFLRGGAQVAKPALMLSRGLLGNQGLRGTAGFMTGFRRSG----ARH
MAV_2473|M.avium_104 MMVQFLRSGPGAARPAVDLCRGLLRNQGWRGSAGFMAGFRRVG----APH
MSMEG_3684|M.smegmatis_MC2_155 MVFQFVRNGTRAVPVGLQLAGDLLRNQGPVGAVGFAAGFRGVGARPRSHG
TH_3530|M.thermoresistible__bu MIGSFLRSGPRAVPAGLGLSRALLVNQGLSGAAGFLAGLRTLG----SHG
Mflv_3431|M.gilvum_PYR-GCK MIGQFARAGLGVVPVGVSLGRSMFANQGIGGSVGFLRGFRGSG----SAG
Mvan_3185|M.vanbaalenii_PYR-1 MIGQFARGGLGAVPAGIALGRSMVANQGLSGALGFLGGFRGLG----AGG
MAB_1289c|M.abscessus_ATCC_199 MISQLLGSGGDGLLASAKLGPQLLKNQGLNGVLGFMRGLKGVH----AAG
MUL_0468|M.ulcerans_Agy99 MKFGNQE-------------------------------------------
*
Mb2068c|M.bovis_AF2122/97 KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS
Rv2042c|M.tuberculosis_H37Rv KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS
MMAR_3015|M.marinum_M QALVSTFLDGVVRGDSQAATRTLTDTATITLGDDDVLELAELIEQLRRAT
MAV_2473|M.avium_104 QRLVRRFLDAVAAGDKFAAAQALSSTAAITLGDRDPIELAELAEQLAGAG
MSMEG_3684|M.smegmatis_MC2_155 RRRFIRLLDDLCAGDEVSVRRTLRRDARVQSGESAPLGASKLTAMTAGGS
TH_3530|M.thermoresistible__bu RKGFGGFLADAATGDEVAVRRRLARGARITLGDDEPMTATALLTRLAGTR
Mflv_3431|M.gilvum_PYR-GCK KRVFARFLDDACGGDEVGMRR-LLSDAPVTLGDGDPLTSSDVVGYLSGGT
Mvan_3185|M.vanbaalenii_PYR-1 GTLFARFLDDACGGDEVGIRR-LVSDAPVTAGDSEPMTSSDLVKQLAGGA
MAB_1289c|M.abscessus_ATCC_199 KQRVQELTAALAARDIPTVTTVLAPEAALSLDGVSEASLAEFASAASSLT
MUL_0468|M.ulcerans_Agy99 --------------------------------------------------
Mb2068c|M.bovis_AF2122/97 WTKVTGAGSTVAVSLASDHRRGIMFADVPWRGNRIN----RIRYFPA---
Rv2042c|M.tuberculosis_H37Rv WTKVTGAGSTVAVSLASDHRRGIMFADVPWRGNRIN----RIRYFPA---
MMAR_3015|M.marinum_M WSKMIGSGSTVTVSVVTDHGRGIMFAELPWRGNEIH----RVRYFPS---
MAV_2473|M.avium_104 LTKMNSAGPAVAVSLHSGHGRAIMFADVAWRANAIN----RIRYFPA---
MSMEG_3684|M.smegmatis_MC2_155 WRKVIVSGASAVAGIDSEAGRAVLIADLTP--TRIR----RVRYFVDDAA
TH_3530|M.thermoresistible__bu ASKVICAGGAVVARIERAGRRDIVIAHADPRPLTIN----RIRYFTEQPQ
Mflv_3431|M.gilvum_PYR-GCK WSKLIASGDAVAARVDTDGHHRILLADTAGGLTRERPTITRVRLFA----
Mvan_3185|M.vanbaalenii_PYR-1 WSKRVSSGRSVAARVEHDGRRSVLIGEIGG-TGRAGAKIARIRLFGDIH-
MAB_1289c|M.abscessus_ATCC_199 VDKLLAAGPSVSATVHLGNRRGIGLFEFSDNSAAPG-TLASVRLYF----
MUL_0468|M.ulcerans_Agy99 --------------------------------------------------
Mb2068c|M.bovis_AF2122/97 ---
Rv2042c|M.tuberculosis_H37Rv ---
MMAR_3015|M.marinum_M ---
MAV_2473|M.avium_104 ---
MSMEG_3684|M.smegmatis_MC2_155 RDG
TH_3530|M.thermoresistible__bu G--
Mflv_3431|M.gilvum_PYR-GCK ---
Mvan_3185|M.vanbaalenii_PYR-1 ---
MAB_1289c|M.abscessus_ATCC_199 ---
MUL_0468|M.ulcerans_Agy99 ---