For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GPTRAELLTAVERSPQAAAVHDRDAWVGLFADGGRIEDPVGSRPHRGPAEIAQFYDTFIGPRDIAFHRDV DIVAGSTVIRDLELEVAMGAADPGTGNAAVTMRIPAYLRYALQDTETDTETGAGPRIAELQAYWELPAMV FQFVRNGTRAVPVGLQLAGDLLRNQGPVGAVGFAAGFRGVGARPRSHGRRRFIRLLDDLCAGDEVSVRRT LRRDARVQSGESAPLGASKLTAMTAGGSWRKVIVSGASAVAGIDSEAGRAVLIADLTPTRIRRVRYFVDD AARDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3684 | - | - | 100% (286) | steroid delta-isomerase |
| M. smegmatis MC2 155 | MSMEG_5867 | - | 7e-05 | 26.71% (146) | steroid delta-isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2068c | - | 4e-59 | 46.40% (278) | hypothetical protein Mb2068c |
| M. gilvum PYR-GCK | Mflv_3431 | - | 3e-62 | 47.16% (282) | nuclear transport factor 2 |
| M. tuberculosis H37Rv | Rv2042c | - | 4e-59 | 46.40% (278) | hypothetical protein Rv2042c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1289c | - | 2e-37 | 36.11% (252) | hypothetical protein MAB_1289c |
| M. marinum M | MMAR_3015 | - | 4e-59 | 44.96% (278) | hypothetical protein MMAR_3015 |
| M. avium 104 | MAV_2473 | - | 7e-64 | 49.64% (276) | steroid delta-isomerase |
| M. thermoresistible (build 8) | TH_3530 | - | 4e-62 | 48.03% (279) | PUTATIVE putative nuclear transport factor 2 |
| M. ulcerans Agy99 | MUL_4084 | - | 3e-06 | 29.41% (136) | ketosteroid isomerase- like protein |
| M. vanbaalenii PYR-1 | Mvan_3185 | - | 3e-64 | 46.81% (282) | nuclear transport factor 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2068c|M.bovis_AF2122/97 -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVG------
Rv2042c|M.tuberculosis_H37Rv -MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVG------
MMAR_3015|M.marinum_M -MALPKRDDLLAAVERSPRAAAAHDRAGWVSLFTSDGRVEDPVG------
MAV_2473|M.avium_104 MVAPLDRQQLLAAVERSPQAAAEHDRAAWVALFTPDGRIEDPVG------
MSMEG_3684|M.smegmatis_MC2_155 --MGPTRAELLTAVERSPQAAAVHDRDAWVGLFADGGRIEDPVG------
TH_3530|M.thermoresistible__bu --MTFTRTEMIAVVERSPHTIEARDRHGWVDLFTPDARIEDPVG------
Mflv_3431|M.gilvum_PYR-GCK --MPFTRADVAAAAQRSLAAAAAHDRETWIGLFTADGRVEDPVG------
Mvan_3185|M.vanbaalenii_PYR-1 --MPFTRADVLSAAQQSLAAAGAHDRGGWIGLFTADARVEDPVG------
MAB_1289c|M.abscessus_ATCC_199 MSSAPFADELLATVQASPAAVGAHDKDTWVGLFATYGQVNDPVG------
MUL_4084|M.ulcerans_Agy99 ---MSSTHPAHEAGRRSREAVTARDKQAWLAVFADDAVVEDPIGPSAFDP
. . * : :*: *: :*: . ::**:*
Mb2068c|M.bovis_AF2122/97 -SQPQVGHEAIGRFYDTFIGPRD-ITFHR-DLDIVSGTVVLRDLELEVAM
Rv2042c|M.tuberculosis_H37Rv -SQPQVGHEAIGRFYDTFIGPRD-ITFHR-DLDIVSGTVVLRDLELEVAM
MMAR_3015|M.marinum_M -SMPHVGHEQIGRFFDTFIGPRD-IKFHR-DLDIVCGTVVLRDVELEVAM
MAV_2473|M.avium_104 -SRPHLGRTQIGRFYDTFIAPRD-IRFHR-DLDVVFGTTVLRDLELEVAM
MSMEG_3684|M.smegmatis_MC2_155 -SRPHRGPAEIAQFYDTFIGPRD-IAFHR-DVDIVAGSTVIRDLELEVAM
TH_3530|M.thermoresistible__bu -SRPHIGRDRIERFYDTFIGPRR-LRLHP-ETDLVVGTTVLRDLRLEVTM
Mflv_3431|M.gilvum_PYR-GCK -SAPHRGRAAIGRFYDTFIAPRT-ITAHVQGEDIVVDTTVLRDVELEIEM
Mvan_3185|M.vanbaalenii_PYR-1 -SAPHRGHVALGHFYDTFIGPRV-ITYRP-DTDIVVGTTVIRDLELDIQM
MAB_1289c|M.abscessus_ATCC_199 -SRPHIGESAIGKFYDTFIAPNT-IVFDV-ENDVVAGMSVLRDLTIHTTM
MUL_4084|M.ulcerans_Agy99 EGKGHRGRAAISAFWDKAIEPTTRIEFFFRDTYQCGNEEANVGHILITTG
. : * : *:*. * * : . . . :
Mb2068c|M.bovis_AF2122/97 DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA
Rv2042c|M.tuberculosis_H37Rv DSAVT--------VFIPAFLRYDLR------PVTGEWQIAALRAYWELPA
MMAR_3015|M.marinum_M AAGVT--------MFVPAFLRYDLR------KASDEWKIAVLRAYWDLPA
MAV_2473|M.avium_104 GPTVT--------MYIPAFLRYDLR------ETNGEWLIGALRAYWELPA
MSMEG_3684|M.smegmatis_MC2_155 GAADPGTGNAAVTMRIPAYLRYALQDTETDTETGAGPRIAELQAYWELPA
TH_3530|M.thermoresistible__bu AAGLP--------LDIPAFLRYDLA------ADGTELRIAALQAFWELPT
Mflv_3431|M.gilvum_PYR-GCK SAAVS--------LRVPTFIRYDLR------ADGDDLQVCALSAYWELPA
Mvan_3185|M.vanbaalenii_PYR-1 APTLT--------MHVPTYIRYDLR------ADGDELKIAALSAYWELPA
MAB_1289c|M.abscessus_ATCC_199 STGVT--------MHIPMHLRYDVVED----GPASSLKIDRLFAYWELRA
MUL_4084|M.ulcerans_Agy99 DYQVT----------AEGVFTYKAN---------DARQLVALRAYWEMDR
. : * : * *:*::
Mb2068c|M.bovis_AF2122/97 MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH
Rv2042c|M.tuberculosis_H37Rv MMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAG----RRH
MMAR_3015|M.marinum_M MMLQFLRGGAQVAKPALMLSRGLLGNQGLRGTAGFMTGFRRSG----ARH
MAV_2473|M.avium_104 MMVQFLRSGPGAARPAVDLCRGLLRNQGWRGSAGFMAGFRRVG----APH
MSMEG_3684|M.smegmatis_MC2_155 MVFQFVRNGTRAVPVGLQLAGDLLRNQGPVGAVGFAAGFRGVGARPRSHG
TH_3530|M.thermoresistible__bu MIGSFLRSGPRAVPAGLGLSRALLVNQGLSGAAGFLAGLRTLG----SHG
Mflv_3431|M.gilvum_PYR-GCK MIGQFARAGLGVVPVGVSLGRSMFANQGIGGSVGFLRGFRGSG----SAG
Mvan_3185|M.vanbaalenii_PYR-1 MIGQFARGGLGAVPAGIALGRSMVANQGLSGALGFLGGFRGLG----AGG
MAB_1289c|M.abscessus_ATCC_199 MISQLLGSGGDGLLASAKLGPQLLKNQGLNGVLGFMRGLKGVH----AAG
MUL_4084|M.ulcerans_Agy99 AAATTRKA------------------------------------------
Mb2068c|M.bovis_AF2122/97 KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS
Rv2042c|M.tuberculosis_H37Rv KKLVETFLNAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGAS
MMAR_3015|M.marinum_M QALVSTFLDGVVRGDSQAATRTLTDTATITLGDDDVLELAELIEQLRRAT
MAV_2473|M.avium_104 QRLVRRFLDAVAAGDKFAAAQALSSTAAITLGDRDPIELAELAEQLAGAG
MSMEG_3684|M.smegmatis_MC2_155 RRRFIRLLDDLCAGDEVSVRRTLRRDARVQSGESAPLGASKLTAMTAGGS
TH_3530|M.thermoresistible__bu RKGFGGFLADAATGDEVAVRRRLARGARITLGDDEPMTATALLTRLAGTR
Mflv_3431|M.gilvum_PYR-GCK KRVFARFLDDACGGDEVGMRR-LLSDAPVTLGDGDPLTSSDVVGYLSGGT
Mvan_3185|M.vanbaalenii_PYR-1 GTLFARFLDDACGGDEVGIRR-LVSDAPVTAGDSEPMTSSDLVKQLAGGA
MAB_1289c|M.abscessus_ATCC_199 KQRVQELTAALAARDIPTVTTVLAPEAALSLDGVSEASLAEFASAASSLT
MUL_4084|M.ulcerans_Agy99 --------------------------------------------------
Mb2068c|M.bovis_AF2122/97 WTKVTGAGSTVAVSLASDHRRGIMFADVPWRGNRIN----RIRYFPA---
Rv2042c|M.tuberculosis_H37Rv WTKVTGAGSTVAVSLASDHRRGIMFADVPWRGNRIN----RIRYFPA---
MMAR_3015|M.marinum_M WSKMIGSGSTVTVSVVTDHGRGIMFAELPWRGNEIH----RVRYFPS---
MAV_2473|M.avium_104 LTKMNSAGPAVAVSLHSGHGRAIMFADVAWRANAIN----RIRYFPA---
MSMEG_3684|M.smegmatis_MC2_155 WRKVIVSGASAVAGIDSEAGRAVLIADLTP--TRIR----RVRYFVDDAA
TH_3530|M.thermoresistible__bu ASKVICAGGAVVARIERAGRRDIVIAHADPRPLTIN----RIRYFTEQPQ
Mflv_3431|M.gilvum_PYR-GCK WSKLIASGDAVAARVDTDGHHRILLADTAGGLTRERPTITRVRLFA----
Mvan_3185|M.vanbaalenii_PYR-1 WSKRVSSGRSVAARVEHDGRRSVLIGEIGG-TGRAGAKIARIRLFGDIH-
MAB_1289c|M.abscessus_ATCC_199 VDKLLAAGPSVSATVHLGNRRGIGLFEFSDNSAAPG-TLASVRLYF----
MUL_4084|M.ulcerans_Agy99 --------------------------------------------------
Mb2068c|M.bovis_AF2122/97 ---
Rv2042c|M.tuberculosis_H37Rv ---
MMAR_3015|M.marinum_M ---
MAV_2473|M.avium_104 ---
MSMEG_3684|M.smegmatis_MC2_155 RDG
TH_3530|M.thermoresistible__bu G--
Mflv_3431|M.gilvum_PYR-GCK ---
Mvan_3185|M.vanbaalenii_PYR-1 ---
MAB_1289c|M.abscessus_ATCC_199 ---
MUL_4084|M.ulcerans_Agy99 ---