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TQASSASPATPDRRAIITEALRKIDDLTARLAVAEKAETEPIAVVGIGCRLPGGVDNADDFWKLLCDGES GVIRVPADRWDADQYYSSDYSVPGTICNREGGFLTSWQPDEFDAEFFSIAPREAAAMDPQQRLLLEVAWE ALEDAGINPRTLRGTSTGVFIGLTTNDYYHSVVGKLRPEDIDPYIPFGNAPNFAAGRLSYFLGVRGPAVV SDTACSSSLVSIHLACQSLRRGESDHALAAGVNLILSPDNNIACSRWGMLAPDGKCKTFDADADGYVRSE GAGVVVLKRLTDALRDGDRVLAVVRGSAVNQDGASSGQTVPNGPAQQELMRKALETSRLEPSDIDYIEAH GTGTSLGDPIELDALSAVYGDRKDSAPLVLGSVKTNLGHLESGAGVTSFIKTVLSVHHGFIPKQLYFKKL TPQACEGAQKFRIASEPLEWPALTRPRRAAVSGFGVSGTNAHIVIEQAPEAEAVAPQPEPPVSTLVVTGK TAPRIASLAGRLADWLQMPEAASVSLADVAETLNHHRAQHTKFATVTAADREQAVAGLRALAEGYPAPGV VPAHDGACGSGTVFLYSGQGSQWAGMGRRLLADEPAFAAAVDELEPDFVAAAGFSLRDVLTSGETVVGID RIQPVLVGVQLALTKLWQSYGVNPDAVIGHSMGEVTAAVVAGALSPADGLKVIATRSRLMKRLSGQGAMA LLELDAEAAEQLIANYSGLTVAVYASPHQTVIAGPPEQVDAAIAEVDKLDKLARRVDVDVASHHPIIDPI LDDLRAELADLKPRQPSIPIIVTTDQRPTDGTCVFDADHWVANLRNPVRFARAVATAGADKAVFVEVSPH PLLGYAIKDTLAGTHHHSIATLQRDANDTVTFHTNLNATHTVRPPKTPARSTRVQIPTTPWHHTHHWIHT SSADVVQDKGIPVSLAEGEKHEWFHQLSWPVRELPAGSTEVSWLVFTDKAGTDLAELLGPGSRALPLSVL DDADALSAALPGVEHVVYAPPVSGQRFHAEPSYAVFGQLRRLVVALAGAADSPKLFVVTRNAQPVADGDR ANPAHAVLWGQGRTLALEHPEFWGGIIDVDETLPPELLAQYLRAEASALPATGADRDDQAVYRGAERRVP RLEPRPLPAVPLTRLESGTSHLVIGATGNVGPHLIRQLADMGAATVVAVSRRGGSQLSELAEELAAGGTT LVEVAADAADEASMAAVFDRFGADLPALEGVYLASLAGGEALLADMTDDDLAPMFRSKIDTATVLHKLSL RTPVRRFVLFSSITGLLGSRAVAHYTAANAFADAFAYARRALGLPATVLDWGLWKSWSDAQPQMKAAGLE PMPNDVAIKMLPAVLGPDAPVQAVVAGADWPRLADAYRMRAAVKVLDHLVSGPGEDADLGAVPAPAWGTV LGEPVSGTSHDHLWRARVLPGERSYPVAHRVRGVEVVPVSVLLQTLSAAAAQLDEAGPNDGPTVAVGDVR FEYPIVADQPKVVHVVADGKALTVWSSSGPDSPEQRWTRHASAELTTAPGGTPAGDQGAVGKTFDGASIA EMQRALGVEGQPFEWAVSDCAATAAGARADVEVPEATESPAAALVDAAVHVARLADADNAQLLLPAGVES LAVAATVGTSGVIEAYRRDVEGDALVVDVLVKGADDSVWVDIRGLNYAPVESAPAPVADESASGATEFVD WSTMTRQQTVAELRTRLRTILGRELGMPDNAVDFDMPFPELGLDSMMAMNLLRDAKALVRTDLSATMLWN HPSISQMSEFVADLLAPQQNAVDEPEPESNENAEDDSDSFSVLDELFSSVESANAGSEGSI*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3125 | - | - | 100% (1812) | beta-ketoacyl synthase |
M. vanbaalenii PYR-1 | Mvan_3126 | - | 0.0 | 52.83% (1380) | beta-ketoacyl synthase |
M. vanbaalenii PYR-1 | Mvan_3124 | - | 0.0 | 39.63% (1847) | beta-ketoacyl synthase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2957 | ppsB | 0.0 | 54.36% (1435) | phenolpthiocerol synthesis type-I polyketide synthase PPSB |
M. gilvum PYR-GCK | Mflv_3392 | - | 0.0 | 80.98% (1830) | acyl transferase domain-containing protein |
M. tuberculosis H37Rv | Rv2932 | ppsB | 0.0 | 54.29% (1435) | phenolpthiocerol synthesis type-I polyketide synthase PPSB |
M. leprae Br4923 | MLBr_02356 | - | 0.0 | 56.36% (1423) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 35.43% (1431) | polyketide synthase |
M. marinum M | MMAR_1775 | ppsB | 0.0 | 52.15% (1417) | phenolpthiocerol synthesis type-I polyketide synthase PpsB |
M. avium 104 | MAV_1763 | - | 0.0 | 34.96% (1456) | tylactone synthase modules 4 & 5 |
M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 35.17% (1473) | type I modular polyketide synthase |
M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 46.97% (826) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2018 | ppsB | 0.0 | 52.09% (1411) | phenolpthiocerol synthesis type-I polyketide synthase PpsB |
CLUSTAL 2.0.9 multiple sequence alignment MAB_0939|M.abscessus_ATCC_1997 -------------------MDSAENPIESTPR------------FAIIGY MSMEG_0408|M.smegmatis_MC2_155 -------------------MVSAEHPIEPTPS------------FAIIGY MAV_1763|M.avium_104 -------------------MSTVEGLRDPASS------------FAIVGY Mvan_3125|M.vanbaalenii_PYR-1 --MTQASSASPATPDRRAIITEALRKIDDLTARLAVAEKAETEPIAVVGI Mflv_3392|M.gilvum_PYR-GCK --MTVAS-GSPASPDRRAIITEALRKIDDLTARLAAAEKAETEPIAVVGI MMAR_1775|M.marinum_M -MRSVYSRISSMTAQQRAALSEEFSRASRTTT---------AEPVAVVGI MUL_2018|M.ulcerans_Agy99 -----------MTAQQRAALSEEFSRASRTTT---------AEPVAVVGI Mb2957|M.bovis_AF2122/97 MMRTAFSRISGMTAQQRTSLADEFDRVSRIAV---------AEPVAVVGI Rv2932|M.tuberculosis_H37Rv MMRTAFSRISGMTAQQRTSLADEFDRVSRIAV---------AEPVAVVGI MLBr_02356|M.leprae_Br4923 -MRTAFSRISGMTTQQRAALIEEFTKLSRIAV---------AEPIAVVGI TH_4621|M.thermoresistible__bu -----------------------VNIVGDTPVN----------AVAVIGM . .*::* MAB_0939|M.abscessus_ATCC_1997 AARFPG-AADAEEFWDVLREGRDAISEVPADRWDAEEFFDPEPGAPGKVV MSMEG_0408|M.smegmatis_MC2_155 AARFPG-AASAEEYWALLRDGREAISDVPKDRWDIEEFFDPDPSTPGKVV MAV_1763|M.avium_104 AARFPG-AADADEFWRVLAEGRDAVSEVPKDRWDADEFFDPDPDAPGKVV Mvan_3125|M.vanbaalenii_PYR-1 GCRLPGGVDNADDFWKLLCDGESGVIRVPADRWDADQYYSSDYSVPGTIC Mflv_3392|M.gilvum_PYR-GCK GCRLPGGVENADGFWRFLSDGGNGVIRVPADRWDADAFYSADYTVPGTIC MMAR_1775|M.marinum_M GCRFPGNVTGPDSFWDLLVEGGNAISGIPAERWDADDYYHPDPLTPGHMT MUL_2018|M.ulcerans_Agy99 GCRFPGNVTGPDSFWDLLVEGGNAISGIPAERWDADDYYHPDPLTPGHMT Mb2957|M.bovis_AF2122/97 GCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFYHPDPLTPGRMT Rv2932|M.tuberculosis_H37Rv GCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFYHPDPLTPGRMT MLBr_02356|M.leprae_Br4923 GCRFPGDVTGPDSFWDLLIDGRNAISRVPADRWDADAFYDPDPLTPGRMT TH_4621|M.thermoresistible__bu ACRLPGGIDSPQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTV ..*:** ..: * * * . : :* :*** : :: .: .** MAB_0939|M.abscessus_ATCC_1997 TRRAGFVEDVTG--FDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGI MSMEG_0408|M.smegmatis_MC2_155 TRRAGFVDDVTG--FDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGI MAV_1763|M.avium_104 TRRAGFVDDVTG--FDAPFFGMSAREARLLDPQHRLLLETAWRAVEHSGT Mvan_3125|M.vanbaalenii_PYR-1 NREGGFLTSWQPDEFDAEFFSIAPREAAAMDPQQRLLLEVAWEALEDAGI Mflv_3392|M.gilvum_PYR-GCK NREGGFLTSWQPDEFDAEFFSIAPREAAAMDPQQRLLLEVAWEALENAGI MMAR_1775|M.marinum_M TKWGAFVADIAG--FDAEFFGITPREAASMDPQQRMLLEVTWEALEHAGI MUL_2018|M.ulcerans_Agy99 TKWGAFVADIAG--FDAEFFGITPREAASMDPQQRMLLEVTWEALEHAGI Mb2957|M.bovis_AF2122/97 TKWGGFVPDVAG--FDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGI Rv2932|M.tuberculosis_H37Rv TKWGGFVPDVAG--FDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGI MLBr_02356|M.leprae_Br4923 TKWGGFVSDIAG--FDAAFFGITPREAAAMDPQQRILLEVAWEALENAGI TH_4621|M.thermoresistible__bu SRWGAFLDDVAG--FDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGL .: ..*: . **. **.:: **. :***:*:*:*.:*.*:*.:* MAB_0939|M.abscessus_ATCC_1997 APTDLAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGR MSMEG_0408|M.smegmatis_MC2_155 APTSLANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGR MAV_1763|M.avium_104 APTDLANTNTGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGR Mvan_3125|M.vanbaalenii_PYR-1 NPRTLRGTSTGVFIGLTTNDYYHSVVGKLRPEDIDPYIPFGNAPNFAAGR Mflv_3392|M.gilvum_PYR-GCK NPRSLRGSATGVFIGLTTNDYYHSVVGRLRPEDIDPYIPFGNAPNFAAGR MMAR_1775|M.marinum_M PTESLAGTRTAVMMGVYFNEYQSMLASSR--ENVDAYTGTGNSHSITAGR MUL_2018|M.ulcerans_Agy99 PTESLAGTRTAVMMGVYFNEYQSMLASSR--ENVDAYTGTGNSHSITAGR Mb2957|M.bovis_AF2122/97 PPDSLGGTRTAVMMGVYFNEYQSMLAASP--QNVDAYSGTGNAHSITVGR Rv2932|M.tuberculosis_H37Rv PPDSLGGTRTAVMMGVYFNEYQSMLAASP--QNVDAYSGTGNAHSITVGR MLBr_02356|M.leprae_Br4923 PPDSLGNSRTGVMIGVYFNEYQSMLASSL--ENVDAYSGTGNAHSITVGR TH_4621|M.thermoresistible__bu TPADVEGSSTGVFVGLSHDDYALLTSDAG--ALEEAYGFTGSAFSMASGR . : : :.*::*: .:* :.* *.: : ** MAB_0939|M.abscessus_ATCC_1997 ISYRLGLQGPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLT MSMEG_0408|M.smegmatis_MC2_155 ISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLT MAV_1763|M.avium_104 ISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLT Mvan_3125|M.vanbaalenii_PYR-1 LSYFLGVRGPAVVSDTACSSSLVSIHLACQSLRRGESDHALAAGVNLILS Mflv_3392|M.gilvum_PYR-GCK LSYFLGVRGPAVVSDTACSSSLVSIHLACQSLRRGESDHALAAGVNLILS MMAR_1775|M.marinum_M ISYLLGLRGPAAAIDTACSSSLSAIHLACQSLRLRETDLALAGGVSATLR MUL_2018|M.ulcerans_Agy99 ISYLLGLRGPAAAIDTACSSSLSAIHLACQSLRLRETDLALAGGVSATLR Mb2957|M.bovis_AF2122/97 ISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLR Rv2932|M.tuberculosis_H37Rv ISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLR MLBr_02356|M.leprae_Br4923 ISYLLGLRGPSLAVDTACSSSLVAVHLACQSLRLRETDLVLAGGVSITLR TH_4621|M.thermoresistible__bu IAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLE ::* **::**: . ******** ::* **::*: * * .**.*. * MAB_0939|M.abscessus_ATCC_1997 PATMITFSHAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDG MSMEG_0408|M.smegmatis_MC2_155 PATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDG MAV_1763|M.avium_104 PATMITFSQAHMLAPDGRCKTFDAAADGYVRGEGCGVLVVKRLEDAIRDG Mvan_3125|M.vanbaalenii_PYR-1 PDNNIACSRWGMLAPDGKCKTFDADADGYVRSEGAGVVVLKRLTDALRDG Mflv_3392|M.gilvum_PYR-GCK PENNIACSRWGMLAPDGLCKTFDADANGYVRSEGAGVVVLKRLSDAVRDG MMAR_1775|M.marinum_M PETQIAISAWGLLSPEGRCATFDAAADGFVRGEGAGVVVLKRLTDALRDQ MUL_2018|M.ulcerans_Agy99 PETQIAISAWGLLSPEGRCATFDAAADGFVRGEGAGVVVLKRLTDALRDQ Mb2957|M.bovis_AF2122/97 PETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDG Rv2932|M.tuberculosis_H37Rv PETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDG MLBr_02356|M.leprae_Br4923 PETQIAISAWGLLSPHGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDG TH_4621|M.thermoresistible__bu PRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDN * . : * :*:* * * :**. *:*:**.**. ::::*** **:** MAB_0939|M.abscessus_ATCC_1997 DRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYL MSMEG_0408|M.smegmatis_MC2_155 DRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYL MAV_1763|M.avium_104 DRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIAEALQRAGIAPGDVDYL Mvan_3125|M.vanbaalenii_PYR-1 DRVLAVVRGSAVNQDGASSGQTVPNGPAQQELMRKALETSRLEPSDIDYI Mflv_3392|M.gilvum_PYR-GCK DRVLAVVRGSAVNQDGASSGQTVPNGPAQQELMRTALKSARLEPSDIDYI MMAR_1775|M.marinum_M DQILAVVRGSAVNQDGRSNGITAPNTAAQCDVIADALRSADVAPESVHYV MUL_2018|M.ulcerans_Agy99 NQILAVVRGSAVNQDGRSNGITAPNTAAQCDVIADALRSADVAPESVHYV Mb2957|M.bovis_AF2122/97 DQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYV Rv2932|M.tuberculosis_H37Rv DQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYV MLBr_02356|M.leprae_Br4923 DLVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVITDALRSSDVAPESVNYV TH_4621|M.thermoresistible__bu DRILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMV : : **:**:* **** : . :.*. ** : ** . : * : : MAB_0939|M.abscessus_ATCC_1997 EAHGTGTSLGDPIEAQAAGAAYG-IGRETNDPLLIGSAKTNIGHLEAAAG MSMEG_0408|M.smegmatis_MC2_155 EAHGTGTSLGDPIEAQAAGEVLG-AGRAPEEPLLIGSAKTNIGHLEAAAG MAV_1763|M.avium_104 EAHGTGTSLGDPIEVQAAGAVLG-AGREASRPLLIGSVKTNIGHLEAAAG Mvan_3125|M.vanbaalenii_PYR-1 EAHGTGTSLGDPIELDALSAVYG--DRKDSAPLVLGSVKTNLGHLESGAG Mflv_3392|M.gilvum_PYR-GCK EAHGTGTSLGDPIELDALSAVYG--DRKDSAPLILGSVKTNLGHLESAAG MMAR_1775|M.marinum_M ETHGTGTQLGDPIEFEALAATYGLIKGQDGDSCALGAVKTNIGHLEAASG MUL_2018|M.ulcerans_Agy99 ETHGTGTQLGDPIEFEALAATYGLIKGQDGYSCALGAVKTNIGHLEAASG Mb2957|M.bovis_AF2122/97 EAHGTGTVLGDPIEFEALAATY----GHGGDACALGAVKTNIGHLEAAAG Rv2932|M.tuberculosis_H37Rv EAHGTGTVLGDPIEFEALAATY----GHGGDACALGAVKTNIGHLEAAAG MLBr_02356|M.leprae_Br4923 ESHGTGTVLGDPIEFEALAATY----GRGESACALGAVKTNLGHLEAAAG TH_4621|M.thermoresistible__bu EAHGTGTPVGDPIEYNSLTQVYG-----KTGPCALTSVKTNFGHAESAAG *:***** :***** :: . . : :.***:** *:.:* MAB_0939|M.abscessus_ATCC_1997 IAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGR MSMEG_0408|M.smegmatis_MC2_155 IAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGK MAV_1763|M.avium_104 IAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQRNGR Mvan_3125|M.vanbaalenii_PYR-1 VTSFIKTVLSVHHGFIPKQLYFKKLTPQACEGAQKFRIASEPLEWPALTR Mflv_3392|M.gilvum_PYR-GCK VTGFIKTVLSVHHGAIPKQLHFTKLTPQAGDGAKKFRIASEPLDWPA-TE MMAR_1775|M.marinum_M VAGFIKAVLAVQHGQIPPNLHFSQWNPAIDAASTRLFVPLDNIAWPSDSG MUL_2018|M.ulcerans_Agy99 VAGFIKAVLAVQHGQIPPNLHFSQWNPAIDAASTRLFVPLDNIAWPSDSG Mb2957|M.bovis_AF2122/97 IAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEG Rv2932|M.tuberculosis_H37Rv IAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEG MLBr_02356|M.leprae_Br4923 IAGFIKTVLAVQRGQIPPNLHFSQWNPAIDAASTRFFVPTENSSWPISDG TH_4621|M.thermoresistible__bu ALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREG ..:*. :::.. :* : * . : * MAB_0939|M.abscessus_ATCC_1997 ---PRIAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGG---RKFSI MSMEG_0408|M.smegmatis_MC2_155 ---PRIAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDP----RRYSV MAV_1763|M.avium_104 ---PRVAGVSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRPPGQRRFHV Mvan_3125|M.vanbaalenii_PYR-1 ---PRRAAVSGFGVSGTNAHIVIEQAPE-AEAVAPQPEPPVS-------T Mflv_3392|M.gilvum_PYR-GCK ---IRRAAVSSFGVSGTNAHIVVEQAPEPAEVPAAQQEPPVS-------T MMAR_1775|M.marinum_M ---PRRAAVSSFGLGGTNAHAIVEQGPELSPAGRRGTDDEVT-------T MUL_2018|M.ulcerans_Agy99 ---PRRAAVSSFGLGGTNAHAIVEQGPELSPAGRRGTDDEVT-------T Mb2957|M.bovis_AF2122/97 ---PRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVS-------T Rv2932|M.tuberculosis_H37Rv ---PRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVS-------T MLBr_02356|M.leprae_Br4923 QAGPRRAAVSSFGLGGTNAHVVIEQGPELTPVTECSSNTAVS-------T TH_4621|M.thermoresistible__bu --CPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAG----PLV * *.**.:*..***.* ::*:.. MAB_0939|M.abscessus_ATCC_1997 LPLSARTPAALAQLADKYRAWLNAHP--EAALADLCFTAGVGRAHLEHRA MSMEG_0408|M.smegmatis_MC2_155 LPLSARTPEALVRLAGEYRDWLRAHP--QARLADVSHTAGTARAHLEQRA MAV_1763|M.avium_104 LPLSARTPAALVQIAGEYRDWLSAHP--DTALADLCLTAGAGRAHFEHRA Mvan_3125|M.vanbaalenii_PYR-1 LVVTGKTAPRIASLAGRLADWLQMPEAASVSLADVAETLNHHRAQHTKFA Mflv_3392|M.gilvum_PYR-GCK LVVTGKTPARIASLAGRLADWLQTPEAAEPTLADIAETLNHRRAQHTRFA MMAR_1775|M.marinum_M LVVAGKTPARVAATAGMLADWMEGPG-AEVALADVAHTLNHHRSRQARFG MUL_2018|M.ulcerans_Agy99 LVVAGKTPARVAATAGMLADWMEGPG-AEVALADVAHTLNHHRSRQARFG Mb2957|M.bovis_AF2122/97 LVVTGKTAQRMAATAQVLADWMEGPG-AEVAVADVAHTVNHHRARQATFG Rv2932|M.tuberculosis_H37Rv LVVTGKTAQRMAATAQVLADWMEGPG-AEVAVADVAHTVNHHRARQATFG MLBr_02356|M.leprae_Br4923 LVVTGKTASRVAAMAGMLADWVEGPG-AEVALADVAHTLNHHRSRHAKFG TH_4621|M.thermoresistible__bu FALSSTSAEELRRTAGRLAEWVEAHT-DEVVPADLAYTLARRRAHRPVRT : ::. :. : * *: . **:. * *:: MAB_0939|M.abscessus_ATCC_1997 ALVVNTREAAVELLSAVADDRPAPGLG-RGESHDTPKTAWLFTGQGSQYP MSMEG_0408|M.smegmatis_MC2_155 ALVVNSRESAIELLGALADDRPAPGLV-RGESHEAPKTAWLFTGQGSQYP MAV_1763|M.avium_104 ALVVDSTGSAGELLAALADDRPAPGLL-RGVCEDAPKTAWLFTGQGSQYA Mvan_3125|M.vanbaalenii_PYR-1 TVTAADREQAVAGLRALAEGYPAPGVVPAHDGACGSGTVFLYSGQGSQWA Mflv_3392|M.gilvum_PYR-GCK TVAAADRDQAIAGLRALAGGYPAPGVVGPNDPALGTGTVFLYSGQGSQWA MMAR_1775|M.marinum_M TVVARERAQAVAGLRALAANQHAPGVVNPADAPPEPGTVFVYSGRGSQWA MUL_2018|M.ulcerans_Agy99 TVVARERAQAVAGLRALAANQHAPGVVNPADAPPEPGTVFVYSGRGSQWA Mb2957|M.bovis_AF2122/97 TVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWA Rv2932|M.tuberculosis_H37Rv TVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWA MLBr_02356|M.leprae_Br4923 TVVARDRIQAVAGLRALAAGKQAPGVVGQQDGTPGSGTVFVYSGRGSQWA TH_4621|M.thermoresistible__bu TVIADGVEALTAGLREVADG---DAPYQPAVGMDDKAPVWVFSGQGSQWA :: . * :* . . ..::::*:***:. MAB_0939|M.abscessus_ATCC_1997 GMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPE--AEETL MSMEG_0408|M.smegmatis_MC2_155 GMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPL MAV_1763|M.avium_104 GMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDDPA--SEATL Mvan_3125|M.vanbaalenii_PYR-1 GMGRRLLADEPAFAAAVDELEPDFVAAAGFSLRDVLTSGETVVG------ Mflv_3392|M.gilvum_PYR-GCK GMGKRLLADEPAFAAAVDELEPDFVAQVGFSLRDVLTSGETVVG------ MMAR_1775|M.marinum_M GMGRQLLADEPAFAAAVAELEPVFLAEAGFSLHDVLANGTELVG------ MUL_2018|M.ulcerans_Agy99 GMGRQLLADEPAFAAAVAELEPVFLAEAGFSLHDVLANGTELVG------ Mb2957|M.bovis_AF2122/97 GMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVG------ Rv2932|M.tuberculosis_H37Rv GMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVG------ MLBr_02356|M.leprae_Br4923 GMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHDVLANGKELVG------ TH_4621|M.thermoresistible__bu GMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG------ **. .*: * .*: : . . .: :.: MAB_0939|M.abscessus_ATCC_1997 RQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSL MSMEG_0408|M.smegmatis_MC2_155 RHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDV MAV_1763|M.avium_104 RQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRV Mvan_3125|M.vanbaalenii_PYR-1 --IDRIQPVLVGVQLALTKLWQSYGVNPDAVIGHSMGEVTAAVVAGALSP Mflv_3392|M.gilvum_PYR-GCK --IDRIQPVLVGVQLALTALWRSYGVTPDAVIGHSMGEVTAAVVSGALSP MMAR_1775|M.marinum_M --IEQIQLGLIGMQLTLTELWRSYGIQPDLVIGHSMGEVAAAVVAGALTP MUL_2018|M.ulcerans_Agy99 --IEQIQLGLIGMQLTLTELWRSYGIQPDLVIGHSMGEVAAAVVAGALTP Mb2957|M.bovis_AF2122/97 --IEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAGALTP Rv2932|M.tuberculosis_H37Rv --IEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAGALTP MLBr_02356|M.leprae_Br4923 --IEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSLGEVAAAVVAGALTA TH_4621|M.thermoresistible__bu --IDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSL * *..::: *: :*:*. *. *:***:*: :** *: .: MAB_0939|M.abscessus_ATCC_1997 EDGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEF--PSLSVAAY MSMEG_0408|M.smegmatis_MC2_155 EDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEY--PSLSVAAY MAV_1763|M.avium_104 EDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEF--PSLSVAAY Mvan_3125|M.vanbaalenii_PYR-1 ADGLKVIATRSRLMKRLSGQGAMALLELDAEAAEQLIANY--SGLTVAVY Mflv_3392|M.gilvum_PYR-GCK ADGLKVIATRSRLMKRLSGQGAMALLELDAEAAEKLIAGY--DGLTVAVY MMAR_1775|M.marinum_M AEGLRVTAVRSRLMAPLSGQGGMALLGLDASQTEALIADY--PQVTLGIY MUL_2018|M.ulcerans_Agy99 AEGLRVTAVRSRLMAPLSGQGGMALLGLDASQTEALIADY--PQVTLGIY Mb2957|M.bovis_AF2122/97 AEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADY--PQVTVGIY Rv2932|M.tuberculosis_H37Rv AEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADY--PQVTVGIY MLBr_02356|M.leprae_Br4923 AEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVDY--SQVTLAIY TH_4621|M.thermoresistible__bu EDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVI :* :: . *.** *.. * *. . .. : : :. MAB_0939|M.abscessus_ATCC_1997 NGAN-TVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEF MSMEG_0408|M.smegmatis_MC2_155 NGAN-TVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDF MAV_1763|M.avium_104 NGAN-TVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLDPILDEF Mvan_3125|M.vanbaalenii_PYR-1 ASPHQTVIAGPPEQVDAAIAEVDKLDKLARRVDVDVASHHPIIDPILDDL Mflv_3392|M.gilvum_PYR-GCK ASAHQTVIAGPPDQVDAAIAVVDAQDKLARRVDVDVASHHPIVDPILEDL MMAR_1775|M.marinum_M NSPRQTVISGPTDQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQM MUL_2018|M.ulcerans_Agy99 NSPRQTVISGPTDQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQM Mb2957|M.bovis_AF2122/97 NSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAM Rv2932|M.tuberculosis_H37Rv NSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAM MLBr_02356|M.leprae_Br4923 NSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQM TH_4621|M.thermoresistible__bu ASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDEL ... **:.*. . : : . : . * * . :*.: : MAB_0939|M.abscessus_ATCC_1997 EAYANQFNYKTPQRILIDNRTGTALGR---SVKLDGAYWRRHARQPVEFA MSMEG_0408|M.smegmatis_MC2_155 ESFAQKLEYREPQRILIDNRTGSALGR---STRLDGAYWRRHARQPVEFA MAV_1763|M.avium_104 ESYANQFDFGPPQRILICNRTGSALGR---SVKLDGAYWRRHARQPVEFA Mvan_3125|M.vanbaalenii_PYR-1 RAELADLKPRQPSIPIIVTTDQRPTDG---TCVFDADHWVANLRNPVRFA Mflv_3392|M.gilvum_PYR-GCK RSELAGLQPRTPTVPIIVTTDGRPTDG---SCVFDADHWVANLRNPVRFA MMAR_1775|M.marinum_M RSELADLAPRTPTIPIISTTYADLGSARESGPTFDAEHWAINMRNPVHFQ MUL_2018|M.ulcerans_Agy99 RSELADLAPRTPTIPIISTTYADLGAARESGPTFDAEHWAINMRNPVHFQ Mb2957|M.bovis_AF2122/97 RSELADLTPRTPTIGIISTTYADLHTQ----PIFDAEHWATNMRNPVRFQ Rv2932|M.tuberculosis_H37Rv RSELADLTPRTPTIGIISTTYADLHTQ----PIFDAEHWATNMRNPVRFQ MLBr_02356|M.leprae_Br4923 RSELADVAPRTPTIPILSTTYADLGSC----PVFDAQHWATNMRNPVHFQ TH_4621|M.thermoresistible__bu EEILADLQPMTPTVPYYSATSYDPREK----PVCDADYWVDNLRHEVRFA . . * *. :* : *: *.* MAB_0939|M.abscessus_ATCC_1997 KSVRTLADMN---CKVLLEIGPQPVLTAAALRAWPDPATAP------RAI MSMEG_0408|M.smegmatis_MC2_155 KSVRTLADMN---CRVLLEIGPRPVLTATALAAWPDPATTP------QVL MAV_1763|M.avium_104 KSVHTLADLG---CKVLLEIGPQPVLTAAALRAWPDPATAP------RAI Mvan_3125|M.vanbaalenii_PYR-1 RAVATAGA----DKAVFVEVSPHPLLGYAIKDTLAGTHHHS--------I Mflv_3392|M.gilvum_PYR-GCK RAVATAGA----DASIFVEVSPHPLLSYAIKDTLTGPHRN---------L MMAR_1775|M.marinum_M QAITAAAT----DKHNFIEISAHPLLTQAILETLHTVQ----PGSKHTCL MUL_2018|M.ulcerans_Agy99 QAITAAAT----DKHNFIEISAHPLLTQAILETLHTVQ----PGSKYTSL Mb2957|M.bovis_AF2122/97 QAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSI Rv2932|M.tuberculosis_H37Rv QAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSI MLBr_02356|M.leprae_Br4923 QAIMTAGT----DHRTFIEISAHPLLTQAITDTLHGTR--------CISI TH_4621|M.thermoresistible__bu AAVQAALEDG---FRVFGELSPHPLLTRAVEQTARGLDMP------VAAL :: : : *:..:*:* : : : MAB_0939|M.abscessus_ATCC_1997 ASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERR MSMEG_0408|M.smegmatis_MC2_155 ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHR MAV_1763|M.avium_104 ASLRRNTADHRQITEALAEAYIVGHLPDFGAAVG-PARKLDLPTYPFQHR Mvan_3125|M.vanbaalenii_PYR-1 ATLQRDAND----TVTFHTNLNATHTVRPPKTPAR-STRVQIPTTPWHHT Mflv_3392|M.gilvum_PYR-GCK PTLQRDTND----TVTFHTNLNATHTVRPPKTPQRGGPRVQLPATPWHHA MMAR_1775|M.marinum_M GTLQRDSDD----TIVFRTNLNTVRTA-PPQTPHPPEPHPQIPTTPWHHT MUL_2018|M.ulcerans_Agy99 GTLQRDSDD----TIVFRTNLNTVRTA-PPQTPHPPEPHPQIPTTPWHHT Mb2957|M.bovis_AF2122/97 GTLQRDADD----TVTFRTNLYTADIAHPPHTCHPPEPHPTIPTTPWQHT Rv2932|M.tuberculosis_H37Rv GTLQRDADD----TVTFRTNLYTADIAHPPHTCHPPEPHPTIPTTPWQHT MLBr_02356|M.leprae_Br4923 GTLQRDADD----TVTFHTNLNNVHTVHPPHTPHPAEPHVTIPSTPWQHT TH_4621|M.thermoresistible__bu PAMRREQEMPHG-VRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRR ::: . . * .: : MAB_0939|M.abscessus_ATCC_1997 QYWFSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDG MSMEG_0408|M.smegmatis_MC2_155 QFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETV MAV_1763|M.avium_104 QYWFSEQRVPPGSQQTS-------TQTTAVRLLEDGRIAELAELLDGASA Mvan_3125|M.vanbaalenii_PYR-1 HHWIHTSSA----------------DVVQ---------DKGIP----VSL Mflv_3392|M.gilvum_PYR-GCK HHWIHIAKP----------------DTVA---------HTGTGPPAGTAL MMAR_1775|M.marinum_M HHWIDNAAS----------------SSPALSRSESRDGTGAALDTRWSPE MUL_2018|M.ulcerans_Agy99 HHWIDNAAS----------------SSPALSRSESRDGTGAALDTRWSPE Mb2957|M.bovis_AF2122/97 HHWIATTHP----------------STAAPEDP----GSNKVVVNGQSTS Rv2932|M.tuberculosis_H37Rv HHWIATTHP----------------STAAPEDP----GSNKVVVNGQSTS MLBr_02356|M.leprae_Br4923 RHWITTPLA----------------STTALQHL----DRNRVTTHATGIG TH_4621|M.thermoresistible__bu KLVLSRENGEQQTRGG------CTITVHPLLGTHVRLPEEPERHVWQADL : : MAB_0939|M.abscessus_ATCC_1997 DQQTLNVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVT MSMEG_0408|M.smegmatis_MC2_155 DEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAA--AD MAV_1763|M.avium_104 DQHTLDVLTKLAAQHNQQRKSRSIAEDRYEIRWEKSTVPGPEAEAT---- Mvan_3125|M.vanbaalenii_PYR-1 AEGEKHEWFHQLSWPVRELPA-----GSTEVSWLVFTDK----------- Mflv_3392|M.gilvum_PYR-GCK AEGEKHEWFHTLTWPVRDLPQ-----GGTDVPWLVLGDD----------- MMAR_1775|M.marinum_M SGSLLDEWSHKVVWAAQSLPDTPSAQTAVHGRWLVLG------------- MUL_2018|M.ulcerans_Agy99 SGSLLDEWSHKVVWAAQSLPDTPSAQTAVHGRWLVLG------------- Mb2957|M.bovis_AF2122/97 ESRALEDWCHQLAWPIRPAVS---ADPPSTAAWLVVA------------- Rv2932|M.tuberculosis_H37Rv ESRALEDWCHQLAWPIRPAVS---ADPPSTAAWLVVA------------- MLBr_02356|M.leprae_Br4923 -NTELDDWIYQLDWPTRPLTSEPGATWASSGSWLVVS------------- TH_4621|M.thermoresistible__bu GTGAQPWLADHQIHTVAALPGAAYCEMALAAAREVIDS------------ MAB_0939|M.abscessus_ATCC_1997 WLLVADAAGAAQPLLDVLTARGQQHRVLALPVSDADEA-ELVEALRSAAD MSMEG_0408|M.smegmatis_MC2_155 WILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEA-QLVDTLRAASA MAV_1763|M.avium_104 WLVVGDDDDAVAPLVDALTARGHQHRILVLPASDADEE-RLEIVLRAAAA Mvan_3125|M.vanbaalenii_PYR-1 -----AGTDLAELLGP---------GSRALPLSVLDD----ADALSAALP Mflv_3392|M.gilvum_PYR-GCK -----DG--LADLLGT---------GSRTAPLSVLDDDGDIAARLHPLLS MMAR_1775|M.marinum_M ------NADLAAELGR--------------GADVLDSD-SEPAALARALS MUL_2018|M.ulcerans_Agy99 ------NADLAAELGR--------------GADVLDSD-SEPAALARALS Mb2957|M.bovis_AF2122/97 ------DNELCHELAR-----AADSRVDSLSPPALAAG-SDPAALLDALR Rv2932|M.tuberculosis_H37Rv ------DNELCHELAR-----AADSRVDSLSPPALAAG-SDPAALLDALR MLBr_02356|M.leprae_Br4923 ------DAGLSDELARLVVLADPASRVEYLAPSALDHDVSTLHDLHNALR TH_4621|M.thermoresistible__bu ------DGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVETAKDG . MAB_0939|M.abscessus_ATCC_1997 EDSALRIVHVAALAGQGSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAP MSMEG_0408|M.smegmatis_MC2_155 G--ELYVVHIAAGDG-AAAPMRDLLRVQHRTLGGLRRLFRAANDAELRSP MAV_1763|M.avium_104 EEAPLRIALVAALDSGTAPSMRSLLRMQHRVLAGTRRLFRAAAAAELRQP Mvan_3125|M.vanbaalenii_PYR-1 GVEHVVYAPPVSGQRFH---AEPSYAVFGQLRRLVVALAGAA----DSPK Mflv_3392|M.gilvum_PYR-GCK DVRHVVYLPATEAARFD---AAPSYRTFHQLRRLVVALAATP----DAPR MMAR_1775|M.marinum_M DVDYVLYAPPVPADPLD---VAEAYQLFHQARRLATAMIANG----SPAK MUL_2018|M.ulcerans_Agy99 DVDYVLYAPPVPADPLD---VAEAYQLFHQARRLATAMIANG----SPAK Mb2957|M.bovis_AF2122/97 GVDNVLYAPPVPGELLD---IESAYQVFHATRRLAAAMVASSATAISPPK Rv2932|M.tuberculosis_H37Rv GVDNVLYAPPVPGELLD---IESAYQVFHATRRLAAAMVASSATAISPPK MLBr_02356|M.leprae_Br4923 GVDNVLYAPSVSTESVDPVDPESGYRLFHAVRRLAAAMVAG----TSKPK TH_4621|M.thermoresistible__bu EHERRATAVLGAADDTEPPQAHDIDALLAEHPTRIEGDELRQWFDQRGVQ MAB_0939|M.abscessus_ATCC_1997 IWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGT MSMEG_0408|M.smegmatis_MC2_155 IWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADT MAV_1763|M.avium_104 IWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSA Mvan_3125|M.vanbaalenii_PYR-1 LFVVTRNAQPVADGDRANPAHAVLWGQGRTLALEHPEFWGGIIDVDETLP Mflv_3392|M.gilvum_PYR-GCK LFVVTRNAQPVTDGDRANPAHAVLWGQGRTLALEHPEFWGGLVDVDESLP MMAR_1775|M.marinum_M LLIATRNAQPIAEGDPANPSHGVLWGLGRTITLEHPEIWGAIIDFDNSVP MUL_2018|M.ulcerans_Agy99 LLIATRNAQPIAEGDPANPSHGVLWGLGRTITLEHPEIWCAIIDFDNSVP Mb2957|M.bovis_AF2122/97 LFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMP Rv2932|M.tuberculosis_H37Rv LFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMP MLBr_02356|M.leprae_Br4923 LVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGSVIDLDASMP TH_4621|M.thermoresistible__bu FGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDACFQ : . : . . * : . . MAB_0939|M.abscessus_ATCC_1997 DEWAQFIGRVSVSGEAS----TREDQLALRGQAVHVPRLVRREELPSG-K MSMEG_0408|M.smegmatis_MC2_155 -EWPRLIARITSPRDG-------EDQIALRGDAVYAPRLVRRTGEPSD-T MAV_1763|M.avium_104 EEWSRLVRVASAPRDPA----VGEDQIALRGSDIYVPRLTRRSGQPAA-A Mvan_3125|M.vanbaalenii_PYR-1 PELLAQYLRAEASALPATG-ADRDDQAVYRGAERRVPRLEPRPLPAVPLT Mflv_3392|M.gilvum_PYR-GCK AELLAHYLRAEAAVVDGSGAADRDDQAVYRAGERRVPRLEPTPLPAVPLT MMAR_1775|M.marinum_M AQVVARQVLDEADA------TDSEDQVVYRSGVRHVPRLRRHSLAAQP-V MUL_2018|M.ulcerans_Agy99 AQVVARQVLDEADA------TDSEDQVVYRSGVRHVPRLRRHSLAAQP-V Mb2957|M.bovis_AF2122/97 AELAVRHVLTAAHG------TDGEDQVVYRSGARHVPRLQRRTLPGKP-V Rv2932|M.tuberculosis_H37Rv AELAVRHVLTAAHG------TDGEDQVVYRSGARHVPRLQRRTLPGKP-V MLBr_02356|M.leprae_Br4923 PELAARCILDEVASQ---DEKDREDQVVYRACLRRAPRLQRRTASAVSSV TH_4621|M.thermoresistible__bu SVAAHPDVQGAGSGLLLPLGVRRLQAFGPTRGARYCYARVTDADGSKAEA : MAB_0939|M.abscessus_ATCC_1997 PLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQR MSMEG_0408|M.smegmatis_MC2_155 PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRR MAV_1763|M.avium_104 ALTLRADATYLVTGGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQRR Mvan_3125|M.vanbaalenii_PYR-1 RLE--SGTSHLVIGATGNVGPHLIRQLADMGAATVVAVSRRGG--SQLSE Mflv_3392|M.gilvum_PYR-GCK RLE--SGTSHLVIGATGNVGPYLIRQLADMGASTIVAASRRGG--SQLSD MMAR_1775|M.marinum_M ALD--AGASQLVIGATGNIGPHLINQLAEMGAKTIVAVSRNPG--QRLQK MUL_2018|M.ulcerans_Agy99 ALD--AGASQLVIGATGNIGPHLINQLAEMGAKTIVAVSRNPG--QRLQK Mb2957|M.bovis_AF2122/97 TLN--ADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKP---GALDE Rv2932|M.tuberculosis_H37Rv TLN--ADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKP---GALDE MLBr_02356|M.leprae_Br4923 KLSSGQDTTQLVIGATGNIGPHLIRQLAAMGATTIVAVSRNPS--TRLLE TH_4621|M.thermoresistible__bu DLDVLDEHGNVLLRVQG---LLMGGAAADGDDRDRVLGERLLTIEWQRRD * :: * : * . * * MAB_0939|M.abscessus_ATCC_1997 IDALAAQ-GCEVRAVTADVADGHD--VARLLAGIQAELPPLAGIVHAAGE MSMEG_0408|M.smegmatis_MC2_155 LDGLREQYACDVRVITADVADAHD--VARLMTTVAAELPPLAGIVHAAGE MAV_1763|M.avium_104 IDALSQQHGCEVRVIAADVADAHH--VARLLGAVRAELPPVAGIVHAAGE Mvan_3125|M.vanbaalenii_PYR-1 LAEELAAGGTTLVEVAADAADEAS--MAAVFDRFGADLPALEGVYLASLA Mflv_3392|M.gilvum_PYR-GCK LTAELAERGTTLVEVAADAADESS--MAAVFDRFGKDLPPLDGIYLASLA MMAR_1775|M.marinum_M LAESLAAEGVNLVIAAADATDEAA--MTALFDRFGADLPPLEGIYLAAFA MUL_2018|M.ulcerans_Agy99 LAESLAAEGVNLVIAAADATDEAA--MTALFDRFGADLPPLEGIYLAAFA Mb2957|M.bovis_AF2122/97 LTQCLAATGTDLIAVAADATDPAA--MQTLFDRFGTELPPLEGIYLAAFA Rv2932|M.tuberculosis_H37Rv LTQCLAATGTDLIAVAADATDPAA--MQTLFDRFGTELPPLEGIYLAAFA MLBr_02356|M.leprae_Br4923 LDKNLAATGTNLISVAADATDPTA--MTALFDRFGVDLPPLEGIYLAAFA TH_4621|M.thermoresistible__bu LPEADSAAGKWLLVSTSATADVSATRLSDALKQAGAESTSMCWPQQADHA : . : :: .:* : : : ..: * MAB_0939|M.abscessus_ATCC_1997 IGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK---LDFFINTSSIA MSMEG_0408|M.smegmatis_MC2_155 IGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRT-DLDFFVSTSSIA MAV_1763|M.avium_104 IGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLR---LDFFVSTSSIA Mvan_3125|M.vanbaalenii_PYR-1 GGEALLADMTDDDLAPMFRSKIDTATVLHKLSLRTP---VRRFVLFSSIT Mflv_3392|M.gilvum_PYR-GCK GGEALLTEMTDEDLSPMFRAKVDAAAVLHKLSLRTP---VRRFVLFSSIT MMAR_1775|M.marinum_M GQPVLLTEMTNDDVTAMFAPKLDAAALLHRLSLKVP---VRHFVLFSSIS MUL_2018|M.ulcerans_Agy99 GQPVLLTEMTNDDVTAMFAPKLDAAALLHRLSLKVP---VRHFVLFSSIS Mb2957|M.bovis_AF2122/97 GRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSP---VRHFVLFSSVS Rv2932|M.tuberculosis_H37Rv GRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSP---VRHFVLFSSVS MLBr_02356|M.leprae_Br4923 GRPVLLSDMTDNDVVAMFRPKLDVASLLHRLSLKQP---VKYFLLFSSIS TH_4621|M.thermoresistible__bu DNVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITREL : : :. . : :: : MAB_0939|M.abscessus_ATCC_1997 AVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESR MSMEG_0408|M.smegmatis_MC2_155 SVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESR MAV_1763|M.avium_104 SVWGGLGQTAYGAANAFLDGLAWRLREQGVNGISVNFGPWAAGMADENAR Mvan_3125|M.vanbaalenii_PYR-1 GLLGSRAVAHYTAANAFADAFAYARRALGLPATVLDWGLWKS-WSDAQPQ Mflv_3392|M.gilvum_PYR-GCK GLLGSRAVAHYTAANAFADAFAYARRTLGLPATVVDWGLWKS-WADAQPQ MMAR_1775|M.marinum_M GLIGSRWLAHYTATSGYLDALAYARRVMGLPATTVNWGLWKS-LADAEHD MUL_2018|M.ulcerans_Agy99 GLIGSRWLAHYTATSGYLDALAYARRVMGLPATTVNWGLWKS-LADAEHD Mb2957|M.bovis_AF2122/97 GLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKS-LADVQKD Rv2932|M.tuberculosis_H37Rv GLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKS-LADVQKD MLBr_02356|M.leprae_Br4923 GLIGSRWLAHYTATSAFLDILGYARRLVGLPATVVAWGLWKS-LADAQQD TH_4621|M.thermoresistible__bu AEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTT . .. : .: . : . : .. . MAB_0939|M.abscessus_ATCC_1997 ARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQ MSMEG_0408|M.smegmatis_MC2_155 ARLEQRGVRTLSPAEALAGMADVVAG----PVQGVVAKIDWSRFLPLYQQ MAV_1763|M.avium_104 ARLAQRGIKTLSPADALAGLADVMAT---AAAQGVVARIDWTRFLPLYQQ Mvan_3125|M.vanbaalenii_PYR-1 MK----AAGLEPMPNDVAIKMLPAVLGPDAPVQAVVAGADWPRLADAYRM Mflv_3392|M.gilvum_PYR-GCK MK----AAGLEPMPNDVAIRMLPAVLSPDAAVQTIVAGADWGRLADAYRM MMAR_1775|M.marinum_M ASQVSLGSGLVPMQDDVAIGALPLVMSQAAGVHSVVVAADWPLLAAAYRT MUL_2018|M.ulcerans_Agy99 ASQVSLGSGLVPMQDDVAIGALPLVMSQAAGVHSVVVAADWPLLAAAYRT Mb2957|M.bovis_AF2122/97 ATQISAESGLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLAAAYRT Rv2932|M.tuberculosis_H37Rv ATQISAESGLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLAAAYRT MLBr_02356|M.leprae_Br4923 ATQVSAESGLQPMTDDVAIGALPLVMSPDAPVHSVVAAADWPLLAAAYQT TH_4621|M.thermoresistible__bu QIDIADDADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQ : : MAB_0939|M.abscessus_ATCC_1997 AGKRGFLAELDREVPSHLAGVAG--AQSGSTQLVERLANAPVQQRKKLLT MSMEG_0408|M.smegmatis_MC2_155 AGRRAFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLIT MAV_1763|M.avium_104 AGQRSLLAELAREIPDFAPAPTP----SGKTGLVERLAGAPVQQRRKLMT Mvan_3125|M.vanbaalenii_PYR-1 RAAVKVLDHLVSGPGEDADLGAVPAPAWGTVLGEPVSGTSHDHLWRARVL Mflv_3392|M.gilvum_PYR-GCK RAAVKVLDHLVNAPDASADLDSVAPPAWGTVLGEAVTGSPHERLWRARLT MMAR_1775|M.marinum_M RGSLRIVDDVLPVSDETTVLE----------------------------- MUL_2018|M.ulcerans_Agy99 RGSLRIVDDVLPVSDETTVLE----------------------------- Mb2957|M.bovis_AF2122/97 RGALRIVDDLLPAPEDVGKGE----------------------------- Rv2932|M.tuberculosis_H37Rv RGALRIVDDLLPAPEDVGKGE----------------------------- MLBr_02356|M.leprae_Br4923 RGVLRMVDDLLPAPGEVLMQE----------------------------- TH_4621|M.thermoresistible__bu AVVDCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFA : MAB_0939|M.abscessus_ATCC_1997 DYLRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIP MSMEG_0408|M.smegmatis_MC2_155 NYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIP MAV_1763|M.avium_104 EFLRNAVAEVTRVDAAEIREDAGFFDLGMDSLMAIELRRHIEQGVGKQIP Mvan_3125|M.vanbaalenii_PYR-1 PGERSYPVAHRVRGVEVVPVSVLLQTLSAAAAQLDEAGPNDGPTVAVGDV Mflv_3392|M.gilvum_PYR-GCK PGERPYPVAHRVRGVEVVPVSVLLQTLSAAAGQLDGA--------AIGDV MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu DVLIAFG------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 VTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLAS---AVTGRTDEPIA MSMEG_0408|M.smegmatis_MC2_155 VTLVMDHPRLSDAADYLLVEVLGLGEQTN--VRQAS---TVTARTDDPIA MAV_1763|M.avium_104 ATLAMDYPRLSDVAEYLLGDVLDLRGQPDAKPAPPAGTPAPAGRTDEPIA Mvan_3125|M.vanbaalenii_PYR-1 RFEYPIVADQPKVVHVVADG----KALTVWSSSGPDSPEQRWTRHASAEL Mflv_3392|M.gilvum_PYR-GCK RFEYPIVADAPKVIHVVFDKGGDSGALSVWSSSAPDTPEQRWTRHAGAQL MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 IVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDPEVAG MSMEG_0408|M.smegmatis_MC2_155 VVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPG MAV_1763|M.avium_104 IVAMACRFPGAADPEAFWELLSGGVDAIREVPEDRFDIDEFYDPDPETPG Mvan_3125|M.vanbaalenii_PYR-1 TTAPGGTPAGDQGAVGKTFDGASIAEMQRALGVEGQPFEWAVSDCAATAA Mflv_3392|M.gilvum_PYR-GCK SDAPSAALSGDQSPGDRVFDSAAIAEMQSALGVQGQPFDWTVSDCTTTAA MMAR_1775|M.marinum_M ------------------------SEFRVAL------------------- MUL_2018|M.ulcerans_Agy99 ------------------------SEFRVAL------------------- Mb2957|M.bovis_AF2122/97 ------------------------SEFRTSL------------------- Rv2932|M.tuberculosis_H37Rv ------------------------SEFRTSL------------------- MLBr_02356|M.leprae_Br4923 ------------------------SEFRKAL------------------- TH_4621|M.thermoresistible__bu -----------RYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGL : : MAB_0939|M.abscessus_ATCC_1997 KTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAG MSMEG_0408|M.smegmatis_MC2_155 KTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAG MAV_1763|M.avium_104 KMYSRFGGYLDQIDEFDPEFFGISPREAVWIDPQQRLVLETVWEGLERAG Mvan_3125|M.vanbaalenii_PYR-1 GARADVEVPEATESPAAALVDAAVHVARLADADNAQLLLPAGVESLAVAA Mflv_3392|M.gilvum_PYR-GCK GARADITLPDTTESPAAALVDVAVHVARLADAGNAQLLLPAGAETLAVTA MMAR_1775|M.marinum_M ---------------------------RNCAPERRHDMLHDQVAMLAANV MUL_2018|M.ulcerans_Agy99 ---------------------------RNCAPERRHDMLHDQVAMLAANV Mb2957|M.bovis_AF2122/97 ---------------------------RSCPAEKRRDMLFDHVGALAATV Rv2932|M.tuberculosis_H37Rv ---------------------------RSCPAEKRRDMLFDHVGALAATV MLBr_02356|M.leprae_Br4923 ---------------------------RTCQAERRHNMLFDHVSALVAKA TH_4621|M.thermoresistible__bu SPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLG : * MAB_0939|M.abscessus_ATCC_1997 YSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGR MSMEG_0408|M.smegmatis_MC2_155 YAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGR MAV_1763|M.avium_104 YSPAALRGSRSGIFVGVGANEYSHLLSAESVDKIEPHFITGNALNAISGR Mvan_3125|M.vanbaalenii_PYR-1 TVGTSGVIEAYRR-D----------------------------VEGDALV Mflv_3392|M.gilvum_PYR-GCK SPGTAGVVEAYRRPD----------------------------AGGDTLV MMAR_1775|M.marinum_M MG------------------------------------------------ MUL_2018|M.ulcerans_Agy99 MG------------------------------------------------ Mb2957|M.bovis_AF2122/97 MG------------------------------------------------ Rv2932|M.tuberculosis_H37Rv MG------------------------------------------------ MLBr_02356|M.leprae_Br4923 MG------------------------------------------------ TH_4621|M.thermoresistible__bu AG------------------------------------------------ MAB_0939|M.abscessus_ATCC_1997 VAFALGFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLS MSMEG_0408|M.smegmatis_MC2_155 VAFALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLS MAV_1763|M.avium_104 VAFALGLEGPAVAVDTACSSSLVAVHQACQALHSGDCDLALAGGVNVLLS Mvan_3125|M.vanbaalenii_PYR-1 VDVLVKGADDSVWVDIRGLNYAPVESAPAPVADESASGATEFVDWSTMTR Mflv_3392|M.gilvum_PYR-GCK VDVLVKGHDGTIWVDIRGLTYAPVESAPAPVVEENASAATEFVDWAAMNR MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 PVTVIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDG MSMEG_0408|M.smegmatis_MC2_155 PVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDG MAV_1763|M.avium_104 PVSNIAASRARMLSPVGRCKTFDATADGYVRSEGCGILVLKRMSDAVRDG Mvan_3125|M.vanbaalenii_PYR-1 QQTVAELRTRLRTILGRELGMPDNAVDFDMPFPELGLDSMMAMNLLRDAK Mflv_3392|M.gilvum_PYR-GCK QQTVAELRTRLRGILARELGMPEDAVDVEMPFPELGLDSMMAMNLLRDAK MMAR_1775|M.marinum_M -------------------LHAGESLDPSTGFFQLGMDSLMSVTLQRALS MUL_2018|M.ulcerans_Agy99 -------------------LHAGESPDPSTGFFQLGMDSLMSVTLQRALS Mb2957|M.bovis_AF2122/97 -------------------MPPTEPLDPSAGFFQLGMDSLMSVTLQRALS Rv2932|M.tuberculosis_H37Rv -------------------MPPTEPLDPSAGFFQLGMDSLMSVTLQRALS MLBr_02356|M.leprae_Br4923 -------------------LLPAETLDPSAGFFQLGMDSLMSVTLQRALS TH_4621|M.thermoresistible__bu ------------------EKVLIHSATGGVGLAAIAIARSVGAQIYATAG . .: MAB_0939|M.abscessus_ATCC_1997 DRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYL MSMEG_0408|M.smegmatis_MC2_155 DRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYL MAV_1763|M.avium_104 DRVCAVIPASAVNQDGASSGLTVPNGGAQQRLIATALSRAGLSGDDVDYL Mvan_3125|M.vanbaalenii_PYR-1 ALVRTDLSATMLWNHPSISQMSEFVADLLAPQQNAVDEPEPESNENAE-- Mflv_3392|M.gilvum_PYR-GCK ALVRIDLSATMLWNNPSIAAMSEFVADLLAPGQQPADDEAPEIGEGGEPD MMAR_1775|M.marinum_M DSLGEFLPPSVVFDYPTVYSLTDYLATILPELETD-------DESTADVY MUL_2018|M.ulcerans_Agy99 DSLGEFLPPSVVFDYPTVYSLTDYLATILPELETD-------DESTADIY Mb2957|M.bovis_AF2122/97 ESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIG-ATAVATQQATDSY Rv2932|M.tuberculosis_H37Rv ESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIG-ATAVATQQATDSY MLBr_02356|M.leprae_Br4923 DSLGEFLPASVVFDYPTVYSLTDYLATILPEFLEP---EAPSGRTTADAY TH_4621|M.thermoresistible__bu SPARRDLLRDMGIEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLPGAAQR : : : MAB_0939|M.abscessus_ATCC_1997 EAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESASGA MSMEG_0408|M.smegmatis_MC2_155 EAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGA MAV_1763|M.avium_104 EAHGTGTALGDPIEVQAAGAVYGATRDTDRPLLIGSVKTNIGHLEAASGV Mvan_3125|M.vanbaalenii_PYR-1 DDSDSFSVLDELFS-----SVESANAGSEGSI------------------ Mflv_3392|M.gilvum_PYR-GCK DDDDSFGLLDELFDSIESDSVESAGAGSEGAN------------------ MMAR_1775|M.marinum_M DELTEAELLEQLSQRLR---------GT---------------------- MUL_2018|M.ulcerans_Agy99 DELTEAELLEQLSQRLR---------GT---------------------- Mb2957|M.bovis_AF2122/97 HELTEAELLEQLSERLR---------GTQ--------------------- Rv2932|M.tuberculosis_H37Rv HELTEAELLEQLSERLR---------GTQ--------------------- MLBr_02356|M.leprae_Br4923 DEFTESELLDQLSERLR---------GTQ--------------------- TH_4621|M.thermoresistible__bu AGLELLSFGGRFIEIGK------RDIYGDTRLGLFPFRRNLAFHGVDLGL . MAB_0939|M.abscessus_ATCC_1997 AGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRP MSMEG_0408|M.smegmatis_MC2_155 AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRV MAV_1763|M.avium_104 AGLIKVVLSLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQTNGRP Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu MADSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEH MAB_0939|M.abscessus_ATCC_1997 RRAGVSSFGFTGTNAHVLIEEAPQPQATPDEDDASTPQSAPVS------V MSMEG_0408|M.smegmatis_MC2_155 RRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAPVEPAATAEAGTDDSPQV MAV_1763|M.avium_104 RRAGVSSFGFTGTNAHVLIEEAPQPVTTQDATPAAESDARPVD------V Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu VGKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGG------------- MAB_0939|M.abscessus_ATCC_1997 LPLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAAL MSMEG_0408|M.smegmatis_MC2_155 LALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAAL MAV_1763|M.avium_104 LPLSARSPEALLALAQRYGEWLHAHPDADIGDLCFTVGAGRAHFEHRAAL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu ----------------------MGGLGLYLAGEMAAAGAGCIVLNGRSAP MAB_0939|M.abscessus_ATCC_1997 VVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMA MSMEG_0408|M.smegmatis_MC2_155 VVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAWLFTGQGSQYPGMA MAV_1763|M.avium_104 VVDSVRSAREALADLADNRTRPGVARGECTDPPTTAWLFTGQGSQYPGMA Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu SGEALRTIEQLRAAGTEVIVECGXXX------------------------ MAB_0939|M.abscessus_ATCC_1997 RELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRH MSMEG_0408|M.smegmatis_MC2_155 RELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQH MAV_1763|M.avium_104 RELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGGEAGKTLRN Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu ----------------RGQPVEVAVPTELRHADEHPDRRGAQLCDEFARG MAB_0939|M.abscessus_ATCC_1997 TSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIED MSMEG_0408|M.smegmatis_MC2_155 TSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD MAV_1763|M.avium_104 TAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACVAGVFSLED Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu EQGAQRNQHRTDAGEG-----------------QRDAHPPGAVGHDQPDP MAB_0939|M.abscessus_ATCC_1997 GARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPN MSMEG_0408|M.smegmatis_MC2_155 GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPN MAV_1763|M.avium_104 GARLMAERGRLFGGLPDGGRMVAVFADAQYVEELANDCPRVSVAAYNGPN Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu GALSDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQGVD MAB_0939|M.abscessus_ATCC_1997 TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAA MSMEG_0408|M.smegmatis_MC2_155 TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAA MAV_1763|M.avium_104 TVLSGPGADLEQIVARGASDGIRCSWLETSHAFHSELLDPVLDEFESYAA Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu GEVVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCR----------- MAB_0939|M.abscessus_ATCC_1997 QVQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAESVRTVAA MSMEG_0408|M.smegmatis_MC2_155 QFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAA MAV_1763|M.avium_104 HLDFAVPTLPLVCNRTGTVLTTETPLDARYWRRHSRQPVQFAESVRTVAA Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------RTTGPAAGAAARRGRTRRRRRPRRPPPPPDRVRHRAG MAB_0939|M.abscessus_ATCC_1997 LGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDRRQIADAL MSMEG_0408|M.smegmatis_MC2_155 LGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADRRQIADAL MAV_1763|M.avium_104 LGCTVLMEIGPQPVLTGAAVQVWPEHLAAPRAIVSLRKGVGDRRQIAEGL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu PAHGPVRR------------------------------------------ MAB_0939|M.abscessus_ATCC_1997 ASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGTA-IEGGGG MSMEG_0408|M.smegmatis_MC2_155 ASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIA-VDGG-T MAV_1763|M.avium_104 AAAYVSGHRPEFAALHRRPRRKLELPTYPFQRRRFWPKASGIAGIDGQGA Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 LPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAM MSMEG_0408|M.smegmatis_MC2_155 AASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAM MAV_1763|M.avium_104 AASGLLGSAKELASGDSVYTSRLSVKSQPWLADHVIYGTVVVPGATYAAM Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 ALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSR MSMEG_0408|M.smegmatis_MC2_155 ALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSR MAV_1763|M.avium_104 ALAAVGPPARVQNVYFYEPIILPDKASREVQLSLHPLQEG-GWSFRVDSR Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 PYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRP MSMEG_0408|M.smegmatis_MC2_155 PYGERGADWSLNAEGTVDT---AGSDPDAAADEQSDPVDEVIERLERMRP MAV_1763|M.avium_104 PYGVPDAEWSLNADGTVVAG-----IEDEPAADPADHIDAVIERLDRNRP Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 MELFEIFADLELAWGPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEP MSMEG_0408|M.smegmatis_MC2_155 QDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEP MAV_1763|M.avium_104 QLLFDSFAESELEWGTTWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTEP Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 MHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFY MSMEG_0408|M.smegmatis_MC2_155 MHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMPRRFY MAV_1763|M.avium_104 MHPVLLDLCTGVVFPAFPALLAAEQGFNDLLLPLRYGQVSLREKMPRRFY Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 CRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREALLRGLG MSMEG_0408|M.smegmatis_MC2_155 CRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLG MAV_1763|M.avium_104 CRGKWRPSALDSETQVFDIDFIDRDGRHLGGIREFTVKRAPREALLRGLG Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GDATRLLYTLGWHEVAVPPVAGEGEESAASIGTWLIAGFDELAAKVPGCI MSMEG_0408|M.smegmatis_MC2_155 GDATRLLYTLGWHEVPPPPSADD------AVGTWLIAGFDELAAKVPGCV MAV_1763|M.avium_104 GDATRLLYTLGWHEVPPQPSNDG---VANPSGTWLIAGFDELGAQLPGCI Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 PLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAARL MSMEG_0408|M.smegmatis_MC2_155 PIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESARL MAV_1763|M.avium_104 PFDRNTDPESFGQLLARAEDRGGPVTGIVWRATQSGGRES--SAESVARL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 EGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAA MSMEG_0408|M.smegmatis_MC2_155 EAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAA MAV_1763|M.avium_104 ETEIAGLLTAVHALQNADGSAVKLPGGLWIVTERGVATESGEPVDPVQAA Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 LWGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVRQ MSMEG_0408|M.smegmatis_MC2_155 LWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVRQ MAV_1763|M.avium_104 LWGLGRTIVNEEPALRCRLVDSDGSEQAVRSLAGLLGAP-LDEPELAVRQ Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAPDE MSMEG_0408|M.smegmatis_MC2_155 GKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDE MAV_1763|M.avium_104 GKLLASRLLPWARSGHLAVPRGTDYVLAPTERGAIDNLRLIEQEAPPPAE Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVE MSMEG_0408|M.smegmatis_MC2_155 GYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLE MAV_1763|M.avium_104 GCVQVRVEAGGLNFREVLNVLGLYPGDPGPLGGDFAGTVTQLGSGVTGLE Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 VGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSF MSMEG_0408|M.smegmatis_MC2_155 IGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF MAV_1763|M.avium_104 VGTRVYGFMQGAFASRFNVPVQLLAPIPDGVSAVDAATIPAAALTARLAF Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 DWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKL MSMEG_0408|M.smegmatis_MC2_155 DWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRL MAV_1763|M.avium_104 DWAQLKPGDRVLIHAASGGVGLAAIQLAQRHGATVFATASTYKRATLRKL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GVKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNG MSMEG_0408|M.smegmatis_MC2_155 GVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGG MAV_1763|M.avium_104 GVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTNEGFIEATVRATAQHG Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 RFAEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSE MSMEG_0408|M.smegmatis_MC2_155 RFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSD MAV_1763|M.avium_104 RFVEIAKRDIWTREQMAAARPDIAYEIVALDWACVEQPEHIHALLTEVSD Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRPDR MSMEG_0408|M.smegmatis_MC2_155 GMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDR MAV_1763|M.avium_104 GLASGEWRPLPAEIYPLAEAKTAFRRMQQARHIGKIVLQMPKPLQPRGDR Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 TYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERS MSMEG_0408|M.smegmatis_MC2_155 SYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERH MAV_1763|M.avium_104 SYLITGGLGAIGLHLAAYLAQLGAGEIVLTSRRAPDAAAWRAIDDITERY Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 KTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQS MSMEG_0408|M.smegmatis_MC2_155 KCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQN MAV_1763|M.avium_104 RCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQS Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 VERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYAT MSMEG_0408|M.smegmatis_MC2_155 PERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYAT MAV_1763|M.avium_104 PERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYST Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 ANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPL MSMEG_0408|M.smegmatis_MC2_155 ANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLIPL MAV_1763|M.avium_104 ANAWLDGLVAARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 DPSAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVLPSAV MSMEG_0408|M.smegmatis_MC2_155 DPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPSAA MAV_1763|M.avium_104 EPTAALAALAEVVANGTGQATVIKANWQRAAKLLGGARPPILDLVLPSAV Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 GEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQPPAATSRFL MSMEG_0408|M.smegmatis_MC2_155 GEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFL MAV_1763|M.avium_104 GEASGDSELLKQLQEIPVAQRAAFITEFLQREVQGFLRLAQPPAATSRFL Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 DLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD MSMEG_0408|M.smegmatis_MC2_155 DLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPD MAV_1763|M.avium_104 DLGTDSLMAVELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLAGQLPD Mvan_3125|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_3392|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_1775|M.marinum_M -------------------------------------------------- MUL_2018|M.ulcerans_Agy99 -------------------------------------------------- Mb2957|M.bovis_AF2122/97 -------------------------------------------------- Rv2932|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02356|M.leprae_Br4923 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- MAB_0939|M.abscessus_ATCC_1997 ADAESAEAPPAVESAEAESGAGPAAASDAVSELKE MSMEG_0408|M.smegmatis_MC2_155 AEAPETA---------------------------- MAV_1763|M.avium_104 AESEPGAAVAANPNPGSETGTGEAEPEREAAPEPS Mvan_3125|M.vanbaalenii_PYR-1 ----------------------------------- Mflv_3392|M.gilvum_PYR-GCK ----------------------------------- MMAR_1775|M.marinum_M ----------------------------------- MUL_2018|M.ulcerans_Agy99 ----------------------------------- Mb2957|M.bovis_AF2122/97 ----------------------------------- Rv2932|M.tuberculosis_H37Rv ----------------------------------- MLBr_02356|M.leprae_Br4923 ----------------------------------- TH_4621|M.thermoresistible__bu -----------------------------------