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M. smegmatis MC2 155 MSMEG_2893 (-)

annotation: oxidoreductase, NAD/FAD-binding
coordinates: 2956384 - 2957439
length: 351

SDVESSTRIARLTVTEVIDESHDARSLVFAVPDEHRDHFGYRPGQFLTLRIPSERTGSVARCYSLASSPH
TDDAHKVTVKRTDGGYGSNWLCDNVSVGSTIESLPPSGVFTPASLDDDFLLWAAGSGITPVMSILKSVLS
AGSGRVILCYANRDERSVIFAAELRELAARHAGRLTVLHWLESVQGLPTRAQLCGFAQLFSGYESFICGP
EPFMAVVRAALTEAGVPRRRIHLEVFQSLSGDPFAEDVPASGPAGPGTDAGAAEAEIELDGTVHQLRWPR
DRNLVDTMLAAGVEVPYSCREGSCGSCAATVLDGEIERGDTPILDAQDIADGLFLACQARPVSDRIRIEF
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2893--100% (351)oxidoreductase, NAD/FAD-binding
M. smegmatis MC2 155MSMEG_6039-e-10855.08% (354) oxidoreductase, electron transfer component
M. smegmatis MC2 155MSMEG_0295-2e-5436.44% (343) oxidoreductase, FAD-binding

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3602hmp1e-10654.19% (358) hemoglobine-like protein
M. gilvum PYR-GCKMflv_1462-1e-10151.82% (357) ferredoxin
M. tuberculosis H37RvRv3571hmp1e-10654.19% (358) hemoglobine-like protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0583c-1e-10854.70% (351) putative oxidoreductase
M. marinum MMMAR_5066hmp1e-10755.49% (355) flavodoxin reductase Hmp
M. avium 104MAV_0590-1e-10355.68% (352) oxidoreductase, electron transfer component
M. thermoresistible (build 8)TH_0316-1e-14873.79% (351) POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP
M. ulcerans Agy99MUL_4142hmp1e-10755.21% (355) flavodoxin reductase Hmp
M. vanbaalenii PYR-1Mvan_2893-1e-15575.85% (352) ferredoxin

CLUSTAL 2.0.9 multiple sequence alignment


Mb3602|M.bovis_AF2122/97            --MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPE
Rv3571|M.tuberculosis_H37Rv         --MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSDDPE
MMAR_5066|M.marinum_M               --MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPR
MUL_4142|M.ulcerans_Agy99           --MTDAIP----DEPLGSHVLELQIAEVVAETDDARSLVFAVPDGSDDPR
MAV_0590|M.avium_104                --MTEADSAQALDEPLGDHVLELQIAEVIAETDDARSLVFAVPDDDGDPD
Mflv_1462|M.gilvum_PYR-GCK          --MTDVAA----DEPLGAHVLELEIADVIDETSDARSLVFRSP---ADAP
MAB_0583c|M.abscessus_ATCC_199      --MT--------DVPLGKHVLEVRIAEVIEETADSRSLVFEIPDG-----
MSMEG_2893|M.smegmatis_MC2_155      --MSDVES--------STRIARLTVTEVIDESHDARSLVFAVP------D
Mvan_2893|M.vanbaalenii_PYR-1       --MLPMSD--------ASRAVPLTVTEVIEESRDAISLVFSVP------G
TH_0316|M.thermoresistible__bu      MVDAEISR--------GPRAVRLTVAAVIDESPDARSLVFEVP------E
                                                    . :   : :: *: *: :: ****  *       

Mb3602|M.bovis_AF2122/97            IPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTA
Rv3571|M.tuberculosis_H37Rv         IPPRRLRYAPGQFLTLRVPSERTGSVARCYSLCSSPYTDDALAVTVKRTA
MMAR_5066|M.marinum_M               IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
MUL_4142|M.ulcerans_Agy99           IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
MAV_0590|M.avium_104                IPPERLRYAPGQFLTLRVPSERTGSVARCYSLCSSPFTDDALTVTVKRTA
Mflv_1462|M.gilvum_PYR-GCK          VAPEKLRYSPGQFLTLRVPSEKTGSVARCYSLCSSPFTGDPLTVTIKRTA
MAB_0583c|M.abscessus_ATCC_199      -AADKFAYAPGQYLTLRIPSDRTGSVARCYSLSSSPHLDDRLAVTVKRTA
MSMEG_2893|M.smegmatis_MC2_155      EHRDHFGYRPGQFLTLRIPSERTGSVARCYSLASSPHTDDAHKVTVKRTD
Mvan_2893|M.vanbaalenii_PYR-1       EHRDRFGYRPGQFLTLRIPSEQTGSVARCYSLASSPHTDDAPKVTVKRTD
TH_0316|M.thermoresistible__bu      EHRTRFVYRPGQFLTLRIPGDRTGSVARCYSLASSPHTDDAMKVTVKRTD
                                        :: * ***:****:*.::**********.***. .*   **:*** 

Mb3602|M.bovis_AF2122/97            DGYASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMS
Rv3571|M.tuberculosis_H37Rv         DGYASNWLCDHAQVGMRIHVLAPSGNFVPTTLDADFLLLAAGSGITPIMS
MMAR_5066|M.marinum_M               DGYASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMS
MUL_4142|M.ulcerans_Agy99           DGYASNWLCDNAHQGMRIHVLAPSGNFVPKTLDDDFLLLAAGSGITPIMS
MAV_0590|M.avium_104                DGYASNWLCDNARPGMRIHVLAPSGNFVPKTLGDDFLLMAAGSGITPIMS
Mflv_1462|M.gilvum_PYR-GCK          DGYASNWLCDNAHAGMKMHVLAPSGTFVPKNLDTDFLLLAAGSGITPMLA
MAB_0583c|M.abscessus_ATCC_199      DGYGSNWICDNAHAGMHMHVLAPSGVFVPKQLDNDFLLLAGGSGVTPMMA
MSMEG_2893|M.smegmatis_MC2_155      GGYGSNWLCDNVSVGSTIESLPPSGVFTPASLDDDFLLWAAGSGITPVMS
Mvan_2893|M.vanbaalenii_PYR-1       GGYGSNWLCDNVSVGATLESLPPSGLFTPRDLDADFLLWAAGSGITPVMS
TH_0316|M.thermoresistible__bu      GGYGSNWLCDNAEPGTTIEALPPAGTFTPASLDGAFLLWAAGSGITPVMS
                                    .**.***:**:.  *  :. *.*:* *.*  *.  *** *.***:**:::

Mb3602|M.bovis_AF2122/97            ICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLES
Rv3571|M.tuberculosis_H37Rv         ICKSALAEGGGQVTLLYANRDDRSVIFGDALRELAAKYPDRLTVLHWLES
MMAR_5066|M.marinum_M               ICKSTLAEGSGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLES
MUL_4142|M.ulcerans_Agy99           ICKSALAEGGGQVTLLYANRDERSVIFADALRELSAKYPDRLTVVHWLES
MAV_0590|M.avium_104                IAKSALSEGSGRVTLLYANRDERSVIFADALRELSAKYPDRLTVLHWLES
Mflv_1462|M.gilvum_PYR-GCK          ILKSALSEGSGHVTLVYANRDEKSVIFAETLRDLANKYPDRLTTIHWLES
MAB_0583c|M.abscessus_ATCC_199      ICKSALSQGSGKVVLIYANRDEQSVIFGAALRELAAKYPDRLTVIHWLES
MSMEG_2893|M.smegmatis_MC2_155      ILKSVLSAGSGRVILCYANRDERSVIFAAELRELAARHAGRLTVLHWLES
Mvan_2893|M.vanbaalenii_PYR-1       ILKSVLTAGTGRVVLCYANRDEASVIFAAELRDLAARYAGRFTVLHWLES
TH_0316|M.thermoresistible__bu      ILKSVLEAGTGRVILCYANRDERSVIFAGELRELAARHAGRFTVLHWLES
                                    * **.*  * *:* * *****: ****.  **:*: ::..*:*.:*****

Mb3602|M.bovis_AF2122/97            LQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHI
Rv3571|M.tuberculosis_H37Rv         LQGLPSASALAKLVAPYTDRPVFICGPGPFMQAARDALAALKVPAQQVHI
MMAR_5066|M.marinum_M               LQGLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHI
MUL_4142|M.ulcerans_Agy99           LQGLPSATALAQLAAPFTGRTAFICGPGPFMEAARVALQTLDVPAGQVHI
MAV_0590|M.avium_104                LQGLPSVTALAQLAAPYTDRPVYICGPGAFMDSAREALETLKVPAAQIHI
Mflv_1462|M.gilvum_PYR-GCK          VQGLPSVSALTALFAPFTSREAFICGPGPFMAAAEEALTASGAAADKIHI
MAB_0583c|M.abscessus_ATCC_199      VQGLPSQQQLATLTAPFAEHEAFICGPGPFMDASEAALKGNGMPHDRVHI
MSMEG_2893|M.smegmatis_MC2_155      VQGLPTRAQLCGFAQLFSGYESFICGPEPFMAVVRAALTEAGVPRRRIHL
Mvan_2893|M.vanbaalenii_PYR-1       IQGLPSHAQLSNFARLFTGYQSFICGPAPYMAVVKETLTDVGIPRDHIHL
TH_0316|M.thermoresistible__bu      VQGLPTTAQMYRFARLFTDHESFVCGPEPFMAVVTAALTEAGVPRNQIHT
                                    :****:   :  :   ::    ::*** .:*     :*     .  ::* 

Mb3602|M.bovis_AF2122/97            EVFKSLESDPFAAVK---VDDSG---DEAPATAVVELDGQTHTVSWPRTA
Rv3571|M.tuberculosis_H37Rv         EVFKSLESDPFAAVK---VDDSG---DEAPATAVVELDGQTHTVSWPRTA
MMAR_5066|M.marinum_M               EVFKSLESDPFAAVT---VEDSA---AEPPATAVVELDGQTHTVSWPRSA
MUL_4142|M.ulcerans_Agy99           EVFKSLESDPFAAVT---VEDSA---AEPPATAVVELDGQTHTVSWPRSA
MAV_0590|M.avium_104                EVFKSLDSDPFAAVK---IEDTAE-GDEPPATAVVELDGETHTVSWPRNA
Mflv_1462|M.gilvum_PYR-GCK          EVFKSLDSDPFAAVT---IDDADDEGDSGPATVVVTLDGETHEVSWPRKA
MAB_0583c|M.abscessus_ATCC_199      EVFRSLESDPFAEVV---LAEPSD-DDEPPATATVELDGETHEVSWPRST
MSMEG_2893|M.smegmatis_MC2_155      EVFQSLSGDPFAEDVPASGPAGPGTDAG-AAEAEIELDGTVHQLRWPRDR
Mvan_2893|M.vanbaalenii_PYR-1       EVFQSLHGDPFAD-----VPVEPFPDEGQAAEAEISIDGRVHHLRWPVGR
TH_0316|M.thermoresistible__bu      EVFRSLTGDPFTDEP-VGEPDGTIADERPPAEAVVVLDGETHVCEWPRTA
                                    ***:** .***:                 .* . : :** .*   **   

Mb3602|M.bovis_AF2122/97            KLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEG
Rv3571|M.tuberculosis_H37Rv         KLLDVLLAAGLDAPFSCREGHCGACACTLRAGKVNMGVNDVLEQQDLDEG
MMAR_5066|M.marinum_M               KLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDG
MUL_4142|M.ulcerans_Agy99           KLLDVLLAAGLDAPFSCREGHCGACAATLRSGKVNMEVNDVLEQQDLDDG
MAV_0590|M.avium_104                KLLDVLLAKGLDAPFSCREGHCGACACTLRKGQVSMEVNDVLEQQDLDEG
Mflv_1462|M.gilvum_PYR-GCK          KLLDVLLNKGLDAPFSCREGHCGACAVLKKSGDIEMEVNDVLEQQDLDEG
MAB_0583c|M.abscessus_ATCC_199      VLLDVLLAKGLDAPFSCREGHCMTCACVLKDGKVRMLVNDALSQNDIDDG
MSMEG_2893|M.smegmatis_MC2_155      NLVDTMLAAGVEVPYSCREGSCGSCAATVLDGEIERGDTPILDAQDIADG
Mvan_2893|M.vanbaalenii_PYR-1       NLVDTMMAAGIEVPYSCREGNCGSCAATVIDGQVDLGNAAILEEQDIADG
TH_0316|M.thermoresistible__bu      TLLDTMLARGLDAPYSCREGNCGSCAATVLEGEVDRGHSDILDPQDVADG
                                     *:*.::  *::.*:***** * :**     *.:       *. :*: :*

Mb3602|M.bovis_AF2122/97            LILACQSRPESDSVEVTYDE
Rv3571|M.tuberculosis_H37Rv         LILACQSRPESDSVEVTYDE
MMAR_5066|M.marinum_M               LILACQSHPESDSVEVTYDE
MUL_4142|M.ulcerans_Agy99           LILACQSHPESDSVEVTYDE
MAV_0590|M.avium_104                LILACQSHPESDSVEVTYDD
Mflv_1462|M.gilvum_PYR-GCK          LILACQAHPTSDSVEVTFDE
MAB_0583c|M.abscessus_ATCC_199      YILACQAVPETDDVNVTFDE
MSMEG_2893|M.smegmatis_MC2_155      LFLACQARPVSDRIRIEF--
Mvan_2893|M.vanbaalenii_PYR-1       LFLACQACPLSDTVKIEF--
TH_0316|M.thermoresistible__bu      LILACQTRPNSDSVRIEF--
                                     :****: * :* :.: :