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VAGKSGAQCRRYGADFAGRDVRRNSRNSGVHGAADAGRRGVSALELRAVVADRRLDVEFSVAAGEVLAIL GPNGAGKSSVLHVIAGLVRPDNGVVRLGERVLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFG PHHRRGTLRSGRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALAAEPDVLLLDEPLTGLD VAAAAAIRAVLRAVVVDSGCAVILISHDLLDVCTLADRVLILEAGRISEIGAAADVLAAPRSNFGARIAG VNLVSGTIGRDGSLHTRFDSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPPHGSPRNTVEVTVAD LQTRGPAVLVRSEDQPDGLPGLAASITVDAAAELKLTPGARVWFSVKAHEVALHQALRRQVAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2736 | modC | - | 100% (413) | molybdenum-transport ATP-binding protein ABC transporter ModC |
| M. marinum M | MMAR_3715 | cysA1 | 9e-36 | 31.96% (341) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. marinum M | MMAR_4203 | sugC | 3e-30 | 33.48% (227) | sugar-transport ATP-binding protein ABC transporter SugC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1890 | modC | 1e-152 | 75.14% (366) | molybdenum ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_3861 | - | 1e-101 | 53.57% (364) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1859 | modC | 1e-153 | 75.14% (366) | molybdenum ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01424 | - | 6e-30 | 31.93% (238) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_2435 | - | 1e-87 | 49.05% (369) | molybdenum ABC transporter ATP-binding protein |
| M. avium 104 | MAV_2860 | - | 1e-147 | 73.22% (366) | molybdenum import ATP-binding protein ModC |
| M. smegmatis MC2 155 | MSMEG_2014 | - | 2e-95 | 50.13% (371) | molybdenum import ATP-binding protein ModC |
| M. thermoresistible (build 8) | TH_1499 | modC | 7e-51 | 58.05% (174) | PROBABLE MOLYBDENUM-TRANSPORT ATP-BINDING PROTEIN ABC |
| M. ulcerans Agy99 | MUL_3018 | modC | 0.0 | 99.20% (373) | molybdenum-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2536 | - | 1e-101 | 53.66% (369) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2736|M.marinum_M MAGKSGAQCRRYGADFAGRDVRRNSRNSGVHGAADAGRRGVSALELRAVV
MUL_3018|M.ulcerans_Agy99 ----------------------------------------MSALELRAVV
Mb1890|M.bovis_AF2122/97 ----------------------------------------MSKLQLRAVV
Rv1859|M.tuberculosis_H37Rv ----------------------------------------MSKLQLRAVV
MAV_2860|M.avium_104 ----------------------------------------MSELQLRAVV
Mflv_3861|M.gilvum_PYR-GCK ----------------------------------------MSGVRVRARL
Mvan_2536|M.vanbaalenii_PYR-1 ----------------------------------------MSSVHVQTRL
MSMEG_2014|M.smegmatis_MC2_155 ----------------------------------------MSGLQVHARV
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 ----------------------------------------MSELRFDAGH
MLBr_01424|M.leprae_Br4923 ---------------------------------MASVTFEQATRQFPDTD
MMAR_2736|M.marinum_M ADRRLDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGVVRLGER
MUL_3018|M.ulcerans_Agy99 ADRRLDVEFSVAAGEVLAILGPNGAGKSSVLHVIAGLVRPDNGVVRLGER
Mb1890|M.bovis_AF2122/97 ADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR
Rv1859|M.tuberculosis_H37Rv ADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDR
MAV_2860|M.avium_104 SQRRFEVEFSVAAGEVLAVLGPNGAGKSTALHVIAGLLRPDRGLVRVGDR
Mflv_3861|M.gilvum_PYR-GCK GERDIDLDVSVADGQVLAVLGPNGAGKSTLLQLVAGLLRPDDGQVEVGDT
Mvan_2536|M.vanbaalenii_PYR-1 HQRAVEFDVEVDEGEVLAVLGPNGAGKSTLLMLIAGLLRPDVGRIELGDA
MSMEG_2014|M.smegmatis_MC2_155 DARDAVFDLTVDDGAVVAVLGPNGAGKSTLLALVAGLLRPDQGRVSVGGT
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 LARGVRARFTVAAGETLAIVGANGAGKSTVLALVGGLLRPDTGEIRLGDH
MLBr_01424|M.leprae_Br4923 RPALDRLDLDVDDGEFVVVVGPSGCGKTTSLRMVAGLETLDSGCIRIGDR
MMAR_2736|M.marinum_M VLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHRRGTLRS
MUL_3018|M.ulcerans_Agy99 VLTDTAAGIDVATHDRKVGLLLQDPLLFPHMSVGANVAFGPHHRRGTLRS
Mb1890|M.bovis_AF2122/97 VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS
Rv1859|M.tuberculosis_H37Rv VLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGS
MAV_2860|M.avium_104 VLTDTAAGIDVPTHDRRVGLLLQDALLFPHMSVAANVAFGPHSRRPMWRR
Mflv_3861|M.gilvum_PYR-GCK VVTDTASGTFVPVHARGVAMLSQQAMLFPHMSVAANVAYAPRCR----GQ
Mvan_2536|M.vanbaalenii_PYR-1 VVTDTATGTFVPAHARRVAMLSQQAMLFPHMTVAANVAYAPRCR----GE
MSMEG_2014|M.smegmatis_MC2_155 VVADTASGVFVPPHARGVAMLAQDPLLFPHMSVAANVSYAPRCK----GH
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 LLTNCATGVFVPTHRRRTALLLQQASLFPHLTVARNVEFG---------I
MLBr_01424|M.leprae_Br4923 DVTHVDP------KDRDVAMVFQNYALYPHMTVAQNLGFALKIS----KI
MMAR_2736|M.marinum_M GRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALAAEPDVL
MUL_3018|M.ulcerans_Agy99 GRRQQRESALRWLAKVGAEQLVDRRPRQLSGGQVQRVAIARALAAEPDVL
Mb1890|M.bovis_AF2122/97 GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL
Rv1859|M.tuberculosis_H37Rv GRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVL
MAV_2860|M.avium_104 GRRAEKATALRWLREVDAEPLADRKPRQLSGGQAQRVAIARALAAEPDVL
Mflv_3861|M.gilvum_PYR-GCK SRSRARASARRWLEAVGAVELADRRPAQLSGGQAQRVALARALAAEPRVL
Mvan_2536|M.vanbaalenii_PYR-1 SRKTARATARRWLTAVGADELADRRPAQLSGGQAQRVAVARALAAEPHLL
MSMEG_2014|M.smegmatis_MC2_155 NRSHARATARHWLRAVDAEDLAERRPSQLSGGQAQRIALARALAAEPRVL
TH_1499|M.thermoresistible__bu --------------------------------------------------
MAB_2435|M.abscessus_ATCC_1997 RGGDVAGVRDRWLEAVGARDLAERRPGELSGGQAQRVAIARALATEPDLV
MLBr_01424|M.leprae_Br4923 SKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVF
MMAR_2736|M.marinum_M LLDEPLTGLDVAAAAAIRAVLRAVVVDSGCAVILISHDLLDVCTLADRVL
MUL_3018|M.ulcerans_Agy99 LLDEPLTGLDVAAAAAIRAVLRAMVVDSGCAVILISHDLLDVCTLADRVL
Mb1890|M.bovis_AF2122/97 LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL
Rv1859|M.tuberculosis_H37Rv LLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVL
MAV_2860|M.avium_104 LLDEPLAGLDVAAAAAIRAVLRRVVTRIGCAAMLVTHDLLDVFTLADRVL
Mflv_3861|M.gilvum_PYR-GCK LLDEPMAALDVTAAPPLRRLLREILREQRRTAIIVTHDVLDAMAVADRAV
Mvan_2536|M.vanbaalenii_PYR-1 LLDEPMAALDVTTAPALRRLLREVLRDSGRTAIVVTHDLLDALALADKVV
MSMEG_2014|M.smegmatis_MC2_155 LLDEPMSALDVTAAPTMRRLLRDLLTAEHRTALIVTHDLLDALAVADTVI
TH_1499|M.thermoresistible__bu --------------------------------VIVTHDLLDVLALADSVL
MAB_2435|M.abscessus_ATCC_1997 LLDEPLAGLDAESAPAIRALLSQVLGRDGQSALIVTHDVMDAVAVADRVL
MLBr_01424|M.leprae_Br4923 LMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVEAMTMGDRVA
: :** ::. ::.* .
MMAR_2736|M.marinum_M ILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRDGSLHT-
MUL_3018|M.ulcerans_Agy99 ILEAGRISEIGAAADVLAAPRSNFGARIAG---VNLVSGTIGRDGSLHT-
Mb1890|M.bovis_AF2122/97 VLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPDGSLRT-
Rv1859|M.tuberculosis_H37Rv VLESGTIAEIGPVADVLTAPRSRFGARIAG---VNLVNGTIGPDGSLRT-
MAV_2860|M.avium_104 VLESGRIAEIGPVADVLTAPRSHFAARVAG---VNLVNGTAEGDGALLA-
Mflv_3861|M.gilvum_PYR-GCK VIEDGRVAEAGPTRTVLTAPRSRFAARIAG---VNLVPGTVSAPGVLRA-
Mvan_2536|M.vanbaalenii_PYR-1 VVDNGRIVESGPARDVLTAPRSDFAARIAG---VNLVAGTVVESGVVRT-
MSMEG_2014|M.smegmatis_MC2_155 VVENGRIVQRGPVREVLAAPRSPFAARIAG---TNLVSGTVTEPGILRT-
TH_1499|M.thermoresistible__bu VLEDGRVVESGPAAAVLATPRSRFAARFAG---VNLVAGTAQPDGTLQT-
MAB_2435|M.abscessus_ATCC_1997 VLDSGRVAELGDTATVLARPTSEFGARFAG---VNLVDGIAGADGALHSG
MLBr_01424|M.leprae_Br4923 VLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSIVDSSVLLG-
:: * : : . : * . * * . * *** . :
MMAR_2736|M.marinum_M --RFDSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPPHGSPRNTV
MUL_3018|M.ulcerans_Agy99 --RFGSQWRGTPARDLDEALDFGQDAIAVFPPTAVAVHLEPPHGSPRNTA
Mb1890|M.bovis_AF2122/97 --QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPPHGSPRNIV
Rv1859|M.tuberculosis_H37Rv --QSGAHWYGTPVQDLPT----GHEAIAVFPPTAVAVYPEPPHGSPRNIV
MAV_2860|M.avium_104 --RSGARWYAAPAAPAGP-LASGQRAVAVFPPTAVAVYREQPHGSPRNTV
Mflv_3861|M.gilvum_PYR-GCK --AWGAEICGTGD------AVPGTAAVALFRPAAVAVHLAPPRGSPRNVM
Mvan_2536|M.vanbaalenii_PYR-1 --SWGSVISGAGD------VATGARAVALFQPAAVAVHLSPPHGSPRNVI
MSMEG_2014|M.smegmatis_MC2_155 --PWYTVISGTGD------TPVGTSAVALFTPAAVSVHLDAPHASPRNVI
TH_1499|M.thermoresistible__bu --AWGSTWFGVADR----EVVVGRPAVAVIAPAAVSVHRKPPEGSPRNTV
MAB_2435|M.abscessus_ATCC_1997 DLAIHGVWAGPGER-----VPRGQHAVAVFTPRDVAVYLSPPGGSPRNVI
MLBr_01424|M.leprae_Br4923 --DWPIRIPREIAS-------AASEVIIGVRPEHFELG-SLGVEVEIDMV
. .: . * . : :
MMAR_2736|M.marinum_M EVTVADLQTRGPAVLVRSEDQPDGLPGLAASITVDAAAELKLT--PGARV
MUL_3018|M.ulcerans_Agy99 EVTVADLQTRGPAVLVRSEDQPDGLPGLAASITVDAAAELKLT--PGARV
Mb1890|M.bovis_AF2122/97 GLTVAEVDTRGPMVLVRGHDQPGGAPGLAACITVDAATELRVA--PGSRV
Rv1859|M.tuberculosis_H37Rv GLTVAEVDTRGPTVLVRGHDQPGGAPGLAACITVDAATELRVA--PGSRV
MAV_2860|M.avium_104 EVTVAEMDVRGAAVLVRGAQQPDGAPGLAAEITVDAASELRLT--PGDRV
Mflv_3861|M.gilvum_PYR-GCK AVTLAEVDVHGAAVRVRGTDQPDGGTGLAADITAAAAADLDLT--PGQTV
Mvan_2536|M.vanbaalenii_PYR-1 AVTIAGIDVHGAGVRVRGTDQPDGATGLAADITAAAAADLDLA--PGQTV
MSMEG_2014|M.smegmatis_MC2_155 AVTIAEMDVHGSTVRIRGADQPDGSAGLSADVTAAAAADLDLA--PGRQV
TH_1499|M.thermoresistible__bu AVTVADLEVHGSAVRVRAADQPDGAPGLAADVTAESAAALELT--PGDEV
MAB_2435|M.abscessus_ATCC_1997 AVSITTLTAHGGSVVVTASR---GATIFTAHITAAAAAELRLA--PDTPA
MLBr_01424|M.leprae_Br4923 EELGADAYLYGRIAGASKVTDQLVVARVDGRNPPAKGSRVRLYTEPGNVH
: * . . . . . .: : : *.
MMAR_2736|M.marinum_M WFSVKAHEVALHQALRRQVAR
MUL_3018|M.ulcerans_Agy99 WFSVKAHEVALHQALRRQVAR
Mb1890|M.bovis_AF2122/97 WFSVKAQEVALHPAPHQHASS
Rv1859|M.tuberculosis_H37Rv WFSVKAQEVALHPAPHQHASS
MAV_2860|M.avium_104 WFSVKAHEVVLYPATAAAER-
Mflv_3861|M.gilvum_PYR-GCK YFAVKAQEVDLHPVPE-----
Mvan_2536|M.vanbaalenii_PYR-1 HFVVKAQEVQVHPASAR----
MSMEG_2014|M.smegmatis_MC2_155 YFVVKAQEVAIHPALRPNV--
TH_1499|M.thermoresistible__bu YFAVKAQEVAIHPAP------
MAB_2435|M.abscessus_ATCC_1997 YFAVKAHEVVIQAAQ------
MLBr_01424|M.leprae_Br4923 FFGVDGHRIS-----------
* *..:.: