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VTVTEQTTARGFPLLPSRLSRGSQATRTTDNTAAALLLTFTVIAILWANSPWAQSYSTLLETHIGFGFGD HHFEMTVKHLVNDALMTFFFFIVGLEVTREFTIGELTDRSRAAVPVVAAAAGLIVPAIVFLAFNPSGDNA HAWGVVISTDTAFLVGALAIIKPKFPARVRLFLLTLAVVDDVGALVAIAVFYSDAIQVGPLVVAVAVLVA LALVRFLPVARGPAYAVLGVALWVALYLAGIHPTLAGVAVALLIPVFTPERRPVERAVDQIRAFRQSPNS QYARAASRSLRESISINERMQTAVGPAVSFVILPLFALVNAGVLLDGQSLMTALRSPLTWGVVAGLVIGK FVGITGATWLMRRTGLGVLAPGLTLRRIAGGAALSGIGFTISLFIVDIAISDSSRQDQARIGVLAASVLA FVFGWAIFRITDWLSPPEPVGLKLLRPVEPDRDHVRGRYDAPLVLVEYGDFECPFCSRATGAIDEVRAHF GDDLLYVWRHFPLERAHPRAFDAARASEAAALQGKFWEMAHELFDHQDDLEWSDMYRYAVAAGCDIEQFD QDVRVHSSKVLHRVTDDAEDAEAMDLNATPTLFVNGIRHKGPWDAASLIRALEAGRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0667 | - | - | 100% (617) | Na+/H+ antiporter NhaA |
| M. vanbaalenii PYR-1 | Mvan_2476 | nhaA | 1e-62 | 36.56% (413) | Na+/H+ antiporter NhaA |
| M. vanbaalenii PYR-1 | Mvan_3237 | - | 1e-16 | 35.86% (145) | DSBA oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0238 | - | 0.0 | 90.58% (616) | Na+/H+ antiporter NhaA |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2991c | - | 7e-59 | 34.87% (413) | Na+/H+ antiporter NhaA |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2775 | nhaA | 1e-61 | 35.34% (399) | Na+/H+ antiporter NhaA |
| M. thermoresistible (build 8) | TH_3766 | - | 4e-58 | 35.22% (423) | PUTATIVE Na+/H+ antiporter NhaA |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2991c|M.abscessus_ATCC_199 ------MRLSQRVFTRGSWAESSRVAEILRKETVGGVLLVVAAVAALLWA
TH_3766|M.thermoresistible__bu VIARPLRRPPRRLLTRGSWAETSRITAILRRETVGGGVLLVVAAAALLWA
MSMEG_2775|M.smegmatis_MC2_155 -MTDQPETFRRRIFSRSSWPEWQRVSELLRTETVGGALLLVAALAALVWA
Mvan_0667|M.vanbaalenii_PYR-1 --MTVTEQTTARGFPLLPSRLSRGSQATRTTDNTAAALLLTFTVIAILWA
Mflv_0238|M.gilvum_PYR-GCK --MTVTEPATQRGFPLLPSRLSRGSKATRTTDNTAAALLLTFTVVAILWA
* :. . :.... :*:. : *::**
MAB_2991c|M.abscessus_ATCC_199 NSPWSSWYYRLGAITVG--PEQLHLHLTLAGWATDGLLAIFFFVVGVELK
TH_3766|M.thermoresistible__bu NSPWSAGYFGLRDATVGGEPLGLHLNLTVGTWAADGLLAIFFLVVGLELK
MSMEG_2775|M.smegmatis_MC2_155 NSPWSAGYDQVSDFVVG--PHSLHLDLSISAWAADGLLAIFFFVVGVELK
Mvan_0667|M.vanbaalenii_PYR-1 NSPWAQSYSTLLETHIGFGFGDHHFEMTVKHLVNDALMTFFFFIVGLEVT
Mflv_0238|M.gilvum_PYR-GCK NSPWAHTYSALLDTHVGFSFGSHHAEMTVKHVVNDALMTFFFFIVGLEVT
****: * : :* * .::: . *.*:::**::**:*:.
MAB_2991c|M.abscessus_ATCC_199 REFVAGDLRDPGRAALPIVAAVGGMLVPAAIYLAVNASGGG-AAMRGWAI
TH_3766|M.thermoresistible__bu REFVAGDLRDPARAVLPIVAAVGGMVAPALIFVVVAAGGGE-GALRGWAI
MSMEG_2775|M.smegmatis_MC2_155 REFVVGDLRDPAKAALPIAAAVGGMIVPAVIFVGVNLVAGHTENLGGWAI
Mvan_0667|M.vanbaalenii_PYR-1 REFTIGELTDRSRAAVPVVAAAAGLIVPAIVFLAFNPSGDN---AHAWGV
Mflv_0238|M.gilvum_PYR-GCK REFTIGELTDRSRAAVPVVAAAAGLILPAVVFLAFNPSGEN---AHAWGV
***. *:* * .:*.:*:.**..*:: ** ::: . . .*.:
MAB_2991c|M.abscessus_ATCC_199 PTATDIAFALAVLAVISTHLPTALRTFLLTLAVVDDLLAVIVIAVFYTDE
TH_3766|M.thermoresistible__bu PTATDIAFAVAVLAVLSTHLPAALRTFLLTLAVVDDLLAVTVIAVFYTEE
MSMEG_2775|M.smegmatis_MC2_155 PVATDIAFALAVLAVIATHLPSALRIFLLTLAVVDDLLAIIVIAVFYTTQ
Mvan_0667|M.vanbaalenii_PYR-1 VISTDTAFLVGALAIIKPKFPARVRLFLLTLAVVDDVGALVAIAVFYSDA
Mflv_0238|M.gilvum_PYR-GCK VISTDTAFLVGALAIIKPKFPARVRLFLLTLAVVDDVGALIAIAVLYSDN
:** ** :..**:: .::*: :* **********: *: .***:*:
MAB_2991c|M.abscessus_ATCC_199 LHWGPLGLALVPLGLFALAVQRRRREWWLLVPLAVATWALVHASGVHATV
TH_3766|M.thermoresistible__bu INTTALGLTLVPLAAFTVCVQRRIRAWWLLIPLGVATWVLMHESGVHATV
MSMEG_2775|M.smegmatis_MC2_155 LSFGPLAGALVTIAVFGLAVQRGVRTPFLLLPLAVVAWALMHASGVHATV
Mvan_0667|M.vanbaalenii_PYR-1 IQVGPLVVAVAVLVALALVRFLPVARGPAYAVLGVALWVALYLAGIHPTL
Mflv_0238|M.gilvum_PYR-GCK IQVAPLVVAVALLGALALVRYLPKARGPAYAVLGAALWIALYLAGIHPTL
: .* ::. : : : *... * :: :*:*.*:
MAB_2991c|M.abscessus_ATCC_199 AGVLLGFTVPVLR----------------------------RDGRTDAHG
TH_3766|M.thermoresistible__bu AGVLLGFAVPVRRS-------------------------AAAGGPAAGPG
MSMEG_2775|M.smegmatis_MC2_155 AGVLLGFTIPVLG----------------------------------RHA
Mvan_0667|M.vanbaalenii_PYR-1 AGVAVALLIPVFTPERRPVERAVDQIRAFRQSPNSQYARAASRSLRESIS
Mflv_0238|M.gilvum_PYR-GCK AGVAVALLIPVFTPERAPVERAVQQIRAFRQSPNSRYARAASRSLRDSIS
*** :.: :** .
MAB_2991c|M.abscessus_ATCC_199 MAEQFEHRLRPLSAGVAVPVFAFFAAGVTLGGFAGLGQALLDPVALGVVL
TH_3766|M.thermoresistible__bu MAEHFEHRLRPLSAGLAVPVFAFFAAGVDFGGLSGLGDALRDPVTLGIIG
MSMEG_2775|M.smegmatis_MC2_155 CADRMEHRLRPLSAGFAVPVFAFFAAGVTVGGLSGFASALSHPVTYGVIA
Mvan_0667|M.vanbaalenii_PYR-1 INERMQTAVGPAVSFVILPLFALVNAGVLLDGQS-LMTALRSPLTWGVVA
Mflv_0238|M.gilvum_PYR-GCK INERLQTAVSPVVSFVILPLFALVNAGVLLDGPS-LTAALRSPLTWGIVA
:::: : * : . :*:**:. *** ..* : : ** *:: *::
MAB_2991c|M.abscessus_ATCC_199 GLLVGKPVGVFLTTYLLARFTRASLDDDLSWLDIAGVALLAGIGFTVSLL
TH_3766|M.thermoresistible__bu GLVVGKPVGIWLTTRLLAAFTRARLDATLRWVDVFGVSLLAGIGFTVSLL
MSMEG_2775|M.smegmatis_MC2_155 GLVLGKPIGVFLTTYVLARFTNASLDEDLAWRDVLGLALLAGIGFTVSLL
Mvan_0667|M.vanbaalenii_PYR-1 GLVIGKFVGITGATWLMRRTGLGVLAPGLTLRRIAGGAALSGIGFTISLF
Mflv_0238|M.gilvum_PYR-GCK GLVVGKFVGIAGATWLIRRTGLGVLAPGLTLRRIAGGAALSGIGFTISLF
**::** :*: :* :: . * * : * : *:*****:**:
MAB_2991c|M.abscessus_ATCC_199 IGELAFGAAESATSGVGAETASHVKVGVLAGSLTSAAVASVVLRLRNRVY
TH_3766|M.thermoresistible__bu IGDLAY--------GTGSIRDDHVKVGVLLGSVTAAALAAAVLRMRNRYY
MSMEG_2775|M.smegmatis_MC2_155 IGELAFE--------NSPIAHDDAKIAVLTGSVLAGLLAAVVLLSRNAVY
Mvan_0667|M.vanbaalenii_PYR-1 IVDIAIS---------DSSRQDQARIGVLAASVLAFVFGWAIFRITDWLS
Mflv_0238|M.gilvum_PYR-GCK IVDIAID---------DPSRQDQARIGVLAASVLAFALGWAIFRITDWLS
* ::* .. ...::.** .*: : .. .:: :
MAB_2991c|M.abscessus_ATCC_199 Q----RIEAKETLDADHDGVPDVFGSAPGDRI------------------
TH_3766|M.thermoresistible__bu R----ILHQQETEDADRDGVPDIYQSPNT---------------------
MSMEG_2775|M.smegmatis_MC2_155 R----RIHEAETVDADDDGVPDIYQPRQDQ--------------------
Mvan_0667|M.vanbaalenii_PYR-1 PPEPVGLKLLRPVEPDRDHVRGRYDAPLVLVEYGDFECPFCSRATGAIDE
Mflv_0238|M.gilvum_PYR-GCK PPEPVGLKLLRPIDPERDHVRGRPDAPLTLVEYGDFECPFCSRVTGAIDE
:. .. :.: * * . .
MAB_2991c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3766|M.thermoresistible__bu --------------------------------------------------
MSMEG_2775|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0667|M.vanbaalenii_PYR-1 VRAHFGDDLLYVWRHFPLERAHPRAFDAARASEAAALQGKFWEMAHELFD
Mflv_0238|M.gilvum_PYR-GCK VRAHFGDDLLYVWRHFPLERAHPRAFDAARASEAAALQGRFWEMTHELFT
MAB_2991c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3766|M.thermoresistible__bu --------------------------------------------------
MSMEG_2775|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0667|M.vanbaalenii_PYR-1 HQDDLEWSDMYRYAVAAGCDIEQFDQDVRVHSSKVLHRVTDDAEDAEAMD
Mflv_0238|M.gilvum_PYR-GCK HQDDLEWSDMYRYAVAAGCDIEQFDQDVRVHSSKVLHRVSDDAEDADAMD
MAB_2991c|M.abscessus_ATCC_199 --------------------------------
TH_3766|M.thermoresistible__bu --------------------------------
MSMEG_2775|M.smegmatis_MC2_155 --------------------------------
Mvan_0667|M.vanbaalenii_PYR-1 LNATPTLFVNGIRHKGPWDAASLIRALEAGRR
Mflv_0238|M.gilvum_PYR-GCK LNATPTLFVNGKRHRGPWDAASLIRALEAGRG