For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VPVSTSGFDAPARLGTLLTAMVTPFKPNGALDTDTAARLANHLVDAGCDGIVVSGTTGESPTTTDDEKIA LLRTVLEAVGDRARVIAGAGTYDTAHSVRMAKASAAEGAHGLLVVTPYYSRPPQAGLAAHFTAVADATDR PVILYDIPPRSVVPIEWETIRALAGHPNIVAIKDAKGDLHGGGQIIAETGLAYYSGDDALNLPWLAMGAV GFISVWGHLAASALRDMMTAFASGDIATARKINVTLGPLSQAQARLGGVTLSKAGLRLQGFEVGEPRLPQ IPATDEQVEELAADMRAAGVLRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2387 | - | - | 100% (303) | dihydrodipicolinate synthase |
| M. vanbaalenii PYR-1 | Mvan_0452 | - | 1e-31 | 32.52% (286) | dihydrodipicolinate synthetase |
| M. vanbaalenii PYR-1 | Mvan_1030 | - | 4e-28 | 32.53% (289) | 5-dehydro-4-deoxyglucarate dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2774c | dapA | 1e-134 | 78.67% (300) | dihydrodipicolinate synthase |
| M. gilvum PYR-GCK | Mflv_4000 | - | 1e-153 | 88.41% (302) | dihydrodipicolinate synthase |
| M. tuberculosis H37Rv | Rv2753c | dapA | 1e-134 | 78.67% (300) | dihydrodipicolinate synthase |
| M. leprae Br4923 | MLBr_01513 | dapA | 1e-132 | 76.67% (300) | dihydrodipicolinate synthase |
| M. abscessus ATCC 19977 | MAB_3084c | - | 1e-117 | 70.34% (290) | dihydrodipicolinate synthase |
| M. marinum M | MMAR_1962 | dapA | 1e-134 | 79.67% (300) | dihydrodipicolinate synthase DapA |
| M. avium 104 | MAV_3644 | dapA | 1e-138 | 81.33% (300) | dihydrodipicolinate synthase |
| M. smegmatis MC2 155 | MSMEG_2684 | dapA | 1e-143 | 83.33% (300) | dihydrodipicolinate synthase |
| M. thermoresistible (build 8) | TH_0834 | dapA | 1e-133 | 77.00% (300) | PROBABLE DIHYDRODIPICOLINATE SYNTHASE DAPA (DHDPS) |
| M. ulcerans Agy99 | MUL_2184 | dapA | 1e-134 | 79.67% (300) | dihydrodipicolinate synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2387|M.vanbaalenii_PYR-1 MPVSTSGFDAPARLGTLLTAMVTPFKPNGALDTDTAARLANHLVDAGCDG
Mflv_4000|M.gilvum_PYR-GCK MPVSTSGFDAPARLGTLLTAMATPFKPDGSLDIETAARLATRLVDAGCDG
MSMEG_2684|M.smegmatis_MC2_155 --MSTSGIDVTAQLGTLLTAMVTPFKPDGSLDLDAAAQLAARLVDSGCDG
TH_0834|M.thermoresistible__bu --VSTGGFDVTAQLGTVLTAMVTPFKKDGSLDLDAAASLANRLVDAGCDG
Mb2774c|M.bovis_AF2122/97 --MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDG
Rv2753c|M.tuberculosis_H37Rv --MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDG
MMAR_1962|M.marinum_M --MSTVGFDVPARLGTLLTAMVTPFGSDGALDLAAAARLANHLVDQGCDG
MUL_2184|M.ulcerans_Agy99 --MSTVGFDVPARLGTLLTAMVTPFGSDGALDLAAAARLANHLVDQGCDG
MLBr_01513|M.leprae_Br4923 --MTTVGFDVPARLGTLLTAMVTPFDADGSVDTAAATRLANRLVDAGCDG
MAV_3644|M.avium_104 --MSTVGFDAPARLGTVLTAMVTPFAADGSLDTAAAARLANHLVDSGCDG
MAB_3084c|M.abscessus_ATCC_199 ----------MARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDG
*:***:****.*** :*::* :*. ** :*** ****
Mvan_2387|M.vanbaalenii_PYR-1 IVVSGTTGESPTTTDDEKIALLRTVLEAVGDRARVIAGAGTYDTAHSVRM
Mflv_4000|M.gilvum_PYR-GCK LVVSGTTGESPTTTDDEKILLLRTVLEAVGDRARIVAGAGTYDTAHSIHL
MSMEG_2684|M.smegmatis_MC2_155 LVLSGTTGESPTTSDDEKIALLRTVVDAVGDRARVIAGAGSYDTAHSVHL
TH_0834|M.thermoresistible__bu LVVSGTTGEAPTTTDDEKLQLLRTVLDAVGDRARIIAGAGTYDTAHSVRL
Mb2774c|M.bovis_AF2122/97 LVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRL
Rv2753c|M.tuberculosis_H37Rv LVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRL
MMAR_1962|M.marinum_M LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTNDTAHSIGL
MUL_2184|M.ulcerans_Agy99 LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTNDTAHSIGL
MLBr_01513|M.leprae_Br4923 LVLSGTTGESPTTTDDEKLQLLRVVLEAVGDRARVIAGAGSYDTAHSVRL
MAV_3644|M.avium_104 LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTYDTAHSVRL
MAB_3084c|M.abscessus_ATCC_199 LVLSGTTGESPVTSDAEKLTLLREVVAAVGDRARIIAGSGTYDTAHSIKL
:*:******:*.*:* ** *** *: *******::**:*: *****: :
Mvan_2387|M.vanbaalenii_PYR-1 AKASAAEGAHGLLVVTPYYSRPPQAGLAAHFTAVADATDRPVILYDIPPR
Mflv_4000|M.gilvum_PYR-GCK AKASAAEGAHGLLVVTPYYSRPPQAGLVAHFTAVADATDLPNILYDIPPR
MSMEG_2684|M.smegmatis_MC2_155 AKASAEAGAHGLLVVTPYYSRPAQAGLLAHFTAVADATDLPVVLYDIPPR
TH_0834|M.thermoresistible__bu AKACQDAGAHGLLLVTPYYSRPPQDGLYAHFTTIADAVEVPIVLYDIPPR
Mb2774c|M.bovis_AF2122/97 AKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGR
Rv2753c|M.tuberculosis_H37Rv AKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGR
MMAR_1962|M.marinum_M AKAAAAEGAHGLLVVTPYYSKPPQSGLLAHFTAVADATELPVLLYDIPGR
MUL_2184|M.ulcerans_Agy99 AKAAAAEGAHGLLVVTPYYSKPPQSGLLAHFTAVADATELPVLLYDIPGR
MLBr_01513|M.leprae_Br4923 VKACAGEGAHGLLVVTPYYSKPPQTGLFAHFTAVADATELPVLLYDIPGR
MAV_3644|M.avium_104 AKACAAEGAHGLLVVTPYYSKPPQRGLIAHFTAVADATELPVLLYDIPGR
MAB_3084c|M.abscessus_ATCC_199 SRECEAAGAHGLLVVTPYYSRPSQAGLLAHFTAVADAVNVPVILYDIPPR
: . ******:******:*.* ** ****::***.: * :***** *
Mvan_2387|M.vanbaalenii_PYR-1 SVVPIEWETIRALAGHPNIVAIKDAKGDLHGGGQIIAETGLAYYSGDDAL
Mflv_4000|M.gilvum_PYR-GCK SVVPIEWDTIRRLAQHPNIVAIKDAKADLHGGGQIIAETGLAYYSGDDAL
MSMEG_2684|M.smegmatis_MC2_155 SVVPIAWDTLRKLAEHPNIVAVKDAKGDLPGGGQIIAETGLAYYSGDDAL
TH_0834|M.thermoresistible__bu SVVPLAWDTIRRLSEHRNIVAIKDAKGDLHGAAQIIAETGLAYYSGDDSL
Mb2774c|M.bovis_AF2122/97 SAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDAL
Rv2753c|M.tuberculosis_H37Rv SAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDAL
MMAR_1962|M.marinum_M SAVPIESETIRALAKHPNIVGVKDAKADLPSGAQIMADTGLAYYSGDDAL
MUL_2184|M.ulcerans_Agy99 SAVPIESETIRALAKHPNIVGVKDAKADLPSGAQIMADTGLAYYSGDDAL
MLBr_01513|M.leprae_Br4923 SVVPIEPDTIRALASHPNIVGVKEAKADLYSGARIMADTGLAYYSGDDAL
MAV_3644|M.avium_104 SVVPIESSTIRALASHPNIVGVKDAKADLHAGGQIIAETGLAYYSGDDAL
MAB_3084c|M.abscessus_ATCC_199 SVVPIDFHIIRELAAHPNIVAVKDAKGDLHGGAQIIAGTDLVYYSGDDPL
*.**: :* *: * ***.:*:**.** ...:*:* *.*.******.*
Mvan_2387|M.vanbaalenii_PYR-1 NLPWLAMGAVGFISVWGHLAASALRDMMTAFASGDIATARKINVTLGPLS
Mflv_4000|M.gilvum_PYR-GCK NLPWLAMGAVGFISVWGHLAASQLRDMLSAFASGDVATARKINVALGPLS
MSMEG_2684|M.smegmatis_MC2_155 NLPWLAMGALGFISVWGHLAAGQLRDMLTAFNSGDVATARKINVNLAPLA
TH_0834|M.thermoresistible__bu NLPWLAVGAVGFISVWGHLAAGQLRDMLTAFNSGDMTTARKIAVTLSPLN
Mb2774c|M.bovis_AF2122/97 NLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLC
Rv2753c|M.tuberculosis_H37Rv NLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLC
MMAR_1962|M.marinum_M NLPWLAMGAIGFISVIGHLAAGQLREMLSAFSSGDVATARKINVAVSPLC
MUL_2184|M.ulcerans_Agy99 NLPWLAMGAIGFISVIGHLAAGQLREMLSAFSSGDVATARKINVAVSPLC
MLBr_01513|M.leprae_Br4923 NLPWLAVGAIGFISVISHLAAGQLRELLSAFGSGDITTARKINVAIGPLC
MAV_3644|M.avium_104 NLPWLAMGATGFISVISHVAANQLRELLSAFTSGDIATARKINATVAPLC
MAB_3084c|M.abscessus_ATCC_199 NLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
*****::** **:** .*..*. **::::*: :**: ****: :.*:
Mvan_2387|M.vanbaalenii_PYR-1 QAQARLGGVTLSKAGLRLQGFEVGEPRLPQIPATDEQVEELAADMRAAGV
Mflv_4000|M.gilvum_PYR-GCK AAQSRLGGVTLSKAGLRLQGFEVGDPRLPQIPANDVQLQALAADMRAASV
MSMEG_2684|M.smegmatis_MC2_155 AAQARLGGVTMSKAGLRLQGFDAGEPRLPQIPATTEEVEALAADMRAATV
TH_0834|M.thermoresistible__bu AAQTRLGGVSMSKAGLRLLGIEVGDPRLPQVPPGPEQLRLLADDMRAAAV
Mb2774c|M.bovis_AF2122/97 NAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASV
Rv2753c|M.tuberculosis_H37Rv NAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASV
MMAR_1962|M.marinum_M NAMTRLGGVTLSKAGLRLQGIEVGDPRLPQVAATAEQIDVLAADMRAASV
MUL_2184|M.ulcerans_Agy99 NAMTRLGGVTLSKAGLRLQGIEVGDPRLPQVAATAEQIDVLAADMRAASV
MLBr_01513|M.leprae_Br4923 SAMDRLGGVTMSKAGLRLQGIDVGDPRLPQMPATAEQIDELAVDMRAASV
MAV_3644|M.avium_104 DAMARLGGVTMSKAGLRLQGIDVGDPRLPQVPATPEQIEALTADMRAASV
MAB_3084c|M.abscessus_ATCC_199 EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGV
* ***.* ****** *::.*:****::.. :: *: ***** *
Mvan_2387|M.vanbaalenii_PYR-1 LRQ
Mflv_4000|M.gilvum_PYR-GCK LR-
MSMEG_2684|M.smegmatis_MC2_155 LR-
TH_0834|M.thermoresistible__bu LR-
Mb2774c|M.bovis_AF2122/97 LR-
Rv2753c|M.tuberculosis_H37Rv LR-
MMAR_1962|M.marinum_M LR-
MUL_2184|M.ulcerans_Agy99 LR-
MLBr_01513|M.leprae_Br4923 LR-
MAV_3644|M.avium_104 LR-
MAB_3084c|M.abscessus_ATCC_199 L--
*