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M. thermoresistible (build 8) TH_0834 (dapA)

annotation: PROBABLE DIHYDRODIPICOLINATE SYNTHASE DAPA (DHDPS) (DIHYDRODIPICOLINATE SYNTHETASE)
coordinates: 1720824 - 1721726
length: 301

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0834 dapA - 100% (301) PROBABLE DIHYDRODIPICOLINATE SYNTHASE DAPA (DHDPS) (DIHYDRODIPICOLINATE SYNTHETASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2774c dapA 1e-124 72.67% (300) dihydrodipicolinate synthase
M. gilvum PYR-GCK Mflv_4000 - 1e-134 78.00% (300) dihydrodipicolinate synthase
M. tuberculosis H37Rv Rv2753c dapA 1e-124 72.67% (300) dihydrodipicolinate synthase
M. leprae Br4923 MLBr_01513 dapA 1e-126 73.67% (300) dihydrodipicolinate synthase
M. abscessus ATCC 19977 MAB_3084c - 1e-114 69.31% (290) dihydrodipicolinate synthase
M. marinum M MMAR_1962 dapA 1e-123 73.67% (300) dihydrodipicolinate synthase DapA
M. avium 104 MAV_3644 dapA 1e-125 74.33% (300) dihydrodipicolinate synthase
M. smegmatis MC2 155 MSMEG_2684 dapA 1e-136 78.67% (300) dihydrodipicolinate synthase
M. ulcerans Agy99 MUL_2184 dapA 1e-123 73.67% (300) dihydrodipicolinate synthase
M. vanbaalenii PYR-1 Mvan_2387 - 1e-132 77.00% (300) dihydrodipicolinate synthase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0834|M.thermoresistible__bu      --VSTGGFDVTAQLGTVLTAMVTPFKKDGSLDLDAAASLANRLVDAGCDG
MSMEG_2684|M.smegmatis_MC2_155      --MSTSGIDVTAQLGTLLTAMVTPFKPDGSLDLDAAAQLAARLVDSGCDG
Mflv_4000|M.gilvum_PYR-GCK          MPVSTSGFDAPARLGTLLTAMATPFKPDGSLDIETAARLATRLVDAGCDG
Mvan_2387|M.vanbaalenii_PYR-1       MPVSTSGFDAPARLGTLLTAMVTPFKPNGALDTDTAARLANHLVDAGCDG
Mb2774c|M.bovis_AF2122/97           --MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDG
Rv2753c|M.tuberculosis_H37Rv        --MTTVGFDVAARLGTLLTAMVTPFSGDGSLDTATAARLANHLVDQGCDG
MMAR_1962|M.marinum_M               --MSTVGFDVPARLGTLLTAMVTPFGSDGALDLAAAARLANHLVDQGCDG
MUL_2184|M.ulcerans_Agy99           --MSTVGFDVPARLGTLLTAMVTPFGSDGALDLAAAARLANHLVDQGCDG
MLBr_01513|M.leprae_Br4923          --MTTVGFDVPARLGTLLTAMVTPFDADGSVDTAAATRLANRLVDAGCDG
MAV_3644|M.avium_104                --MSTVGFDAPARLGTVLTAMVTPFAADGSLDTAAAARLANHLVDSGCDG
MAB_3084c|M.abscessus_ATCC_199      ----------MARLGTVLTAMVTPFDAEGALDVDTAVRLAAHLVDAGCDG
                                               *:***:****.***  :*::*  :*. ** :*** ****

TH_0834|M.thermoresistible__bu      LVVSGTTGEAPTTTDDEKLQLLRTVLDAVGDRARIIAGAGTYDTAHSVRL
MSMEG_2684|M.smegmatis_MC2_155      LVLSGTTGESPTTSDDEKIALLRTVVDAVGDRARVIAGAGSYDTAHSVHL
Mflv_4000|M.gilvum_PYR-GCK          LVVSGTTGESPTTTDDEKILLLRTVLEAVGDRARIVAGAGTYDTAHSIHL
Mvan_2387|M.vanbaalenii_PYR-1       IVVSGTTGESPTTTDDEKIALLRTVLEAVGDRARVIAGAGTYDTAHSVRM
Mb2774c|M.bovis_AF2122/97           LVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRL
Rv2753c|M.tuberculosis_H37Rv        LVVSGTTGESPTTTDGEKIELLRAVLEAVGDRARVIAGAGTYDTAHSIRL
MMAR_1962|M.marinum_M               LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTNDTAHSIGL
MUL_2184|M.ulcerans_Agy99           LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTNDTAHSIGL
MLBr_01513|M.leprae_Br4923          LVLSGTTGESPTTTDDEKLQLLRVVLEAVGDRARVIAGAGSYDTAHSVRL
MAV_3644|M.avium_104                LVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTYDTAHSVRL
MAB_3084c|M.abscessus_ATCC_199      LVLSGTTGESPVTSDAEKLTLLREVVAAVGDRARIIAGSGTYDTAHSIKL
                                    :*:******:*.*:* **  *** *: *******::**:*: *****: :

TH_0834|M.thermoresistible__bu      AKACQDAGAHGLLLVTPYYSRPPQDGLYAHFTTIADAVEVPIVLYDIPPR
MSMEG_2684|M.smegmatis_MC2_155      AKASAEAGAHGLLVVTPYYSRPAQAGLLAHFTAVADATDLPVVLYDIPPR
Mflv_4000|M.gilvum_PYR-GCK          AKASAAEGAHGLLVVTPYYSRPPQAGLVAHFTAVADATDLPNILYDIPPR
Mvan_2387|M.vanbaalenii_PYR-1       AKASAAEGAHGLLVVTPYYSRPPQAGLAAHFTAVADATDRPVILYDIPPR
Mb2774c|M.bovis_AF2122/97           AKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGR
Rv2753c|M.tuberculosis_H37Rv        AKACAAEGAHGLLVVTPYYSKPPQRGLQAHFTAVADATELPMLLYDIPGR
MMAR_1962|M.marinum_M               AKAAAAEGAHGLLVVTPYYSKPPQSGLLAHFTAVADATELPVLLYDIPGR
MUL_2184|M.ulcerans_Agy99           AKAAAAEGAHGLLVVTPYYSKPPQSGLLAHFTAVADATELPVLLYDIPGR
MLBr_01513|M.leprae_Br4923          VKACAGEGAHGLLVVTPYYSKPPQTGLFAHFTAVADATELPVLLYDIPGR
MAV_3644|M.avium_104                AKACAAEGAHGLLVVTPYYSKPPQRGLIAHFTAVADATELPVLLYDIPGR
MAB_3084c|M.abscessus_ATCC_199      SRECEAAGAHGLLVVTPYYSRPSQAGLLAHFTAVADAVNVPVILYDIPPR
                                     : .   ******:******:*.* ** ****::***.: * :***** *

TH_0834|M.thermoresistible__bu      SVVPLAWDTIRRLSEHRNIVAIKDAKGDLHGAAQIIAETGLAYYSGDDSL
MSMEG_2684|M.smegmatis_MC2_155      SVVPIAWDTLRKLAEHPNIVAVKDAKGDLPGGGQIIAETGLAYYSGDDAL
Mflv_4000|M.gilvum_PYR-GCK          SVVPIEWDTIRRLAQHPNIVAIKDAKADLHGGGQIIAETGLAYYSGDDAL
Mvan_2387|M.vanbaalenii_PYR-1       SVVPIEWETIRALAGHPNIVAIKDAKGDLHGGGQIIAETGLAYYSGDDAL
Mb2774c|M.bovis_AF2122/97           SAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDAL
Rv2753c|M.tuberculosis_H37Rv        SAVPIEPDTIRALASHPNIVGVKDAKADLHSGAQIMADTGLAYYSGDDAL
MMAR_1962|M.marinum_M               SAVPIESETIRALAKHPNIVGVKDAKADLPSGAQIMADTGLAYYSGDDAL
MUL_2184|M.ulcerans_Agy99           SAVPIESETIRALAKHPNIVGVKDAKADLPSGAQIMADTGLAYYSGDDAL
MLBr_01513|M.leprae_Br4923          SVVPIEPDTIRALASHPNIVGVKEAKADLYSGARIMADTGLAYYSGDDAL
MAV_3644|M.avium_104                SVVPIESSTIRALASHPNIVGVKDAKADLHAGGQIIAETGLAYYSGDDAL
MAB_3084c|M.abscessus_ATCC_199      SVVPIDFHIIRELAAHPNIVAVKDAKGDLHGGAQIIAGTDLVYYSGDDPL
                                    *.**:    :* *: * ***.:*:**.** ...:*:* *.*.******.*

TH_0834|M.thermoresistible__bu      NLPWLAVGAVGFISVWGHLAAGQLRDMLTAFNSGDMTTARKIAVTLSPLN
MSMEG_2684|M.smegmatis_MC2_155      NLPWLAMGALGFISVWGHLAAGQLRDMLTAFNSGDVATARKINVNLAPLA
Mflv_4000|M.gilvum_PYR-GCK          NLPWLAMGAVGFISVWGHLAASQLRDMLSAFASGDVATARKINVALGPLS
Mvan_2387|M.vanbaalenii_PYR-1       NLPWLAMGAVGFISVWGHLAASALRDMMTAFASGDIATARKINVTLGPLS
Mb2774c|M.bovis_AF2122/97           NLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLC
Rv2753c|M.tuberculosis_H37Rv        NLPWLAMGATGFISVIAHLAAGQLRELLSAFGSGDIATARKINIAVAPLC
MMAR_1962|M.marinum_M               NLPWLAMGAIGFISVIGHLAAGQLREMLSAFSSGDVATARKINVAVSPLC
MUL_2184|M.ulcerans_Agy99           NLPWLAMGAIGFISVIGHLAAGQLREMLSAFSSGDVATARKINVAVSPLC
MLBr_01513|M.leprae_Br4923          NLPWLAVGAIGFISVISHLAAGQLRELLSAFGSGDITTARKINVAIGPLC
MAV_3644|M.avium_104                NLPWLAMGATGFISVISHVAANQLRELLSAFTSGDIATARKINATVAPLC
MAB_3084c|M.abscessus_ATCC_199      NLPWLSVGAVGFVSVISHFVAGPLRELLAAYNAGDVETARKLNAQVAPIT
                                    *****::** **:** .*..*. **::::*: :**: ****:   :.*: 

TH_0834|M.thermoresistible__bu      AAQTRLGGVSMSKAGLRLLGIEVGDPRLPQVPPGPEQLRLLADDMRAAAV
MSMEG_2684|M.smegmatis_MC2_155      AAQARLGGVTMSKAGLRLQGFDAGEPRLPQIPATTEEVEALAADMRAATV
Mflv_4000|M.gilvum_PYR-GCK          AAQSRLGGVTLSKAGLRLQGFEVGDPRLPQIPANDVQLQALAADMRAASV
Mvan_2387|M.vanbaalenii_PYR-1       QAQARLGGVTLSKAGLRLQGFEVGEPRLPQIPATDEQVEELAADMRAAGV
Mb2774c|M.bovis_AF2122/97           NAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASV
Rv2753c|M.tuberculosis_H37Rv        NAMSRLGGVTLSKAGLRLQGIDVGDPRLPQVAATPEQIDALAADMRAASV
MMAR_1962|M.marinum_M               NAMTRLGGVTLSKAGLRLQGIEVGDPRLPQVAATAEQIDVLAADMRAASV
MUL_2184|M.ulcerans_Agy99           NAMTRLGGVTLSKAGLRLQGIEVGDPRLPQVAATAEQIDVLAADMRAASV
MLBr_01513|M.leprae_Br4923          SAMDRLGGVTMSKAGLRLQGIDVGDPRLPQMPATAEQIDELAVDMRAASV
MAV_3644|M.avium_104                DAMARLGGVTMSKAGLRLQGIDVGDPRLPQVPATPEQIEALTADMRAASV
MAB_3084c|M.abscessus_ATCC_199      EACRRLGAVGAVKAGLRLQGIEVGDPRLPNVPPSPEQIEGLAADMRAAGV
                                     *  ***.*   ****** *::.*:****::..   ::  *: ***** *

TH_0834|M.thermoresistible__bu      LR-
MSMEG_2684|M.smegmatis_MC2_155      LR-
Mflv_4000|M.gilvum_PYR-GCK          LR-
Mvan_2387|M.vanbaalenii_PYR-1       LRQ
Mb2774c|M.bovis_AF2122/97           LR-
Rv2753c|M.tuberculosis_H37Rv        LR-
MMAR_1962|M.marinum_M               LR-
MUL_2184|M.ulcerans_Agy99           LR-
MLBr_01513|M.leprae_Br4923          LR-
MAV_3644|M.avium_104                LR-
MAB_3084c|M.abscessus_ATCC_199      L--
                                    *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0834	dapA	-	100% (301)	PROBABLE DIHYDRODIPICOLINATE SYNTHASE DAPA (DHDPS) (DIHYDRODIPICOLINATE SYNTHETASE)