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VSLQDRFAPERLIAAACEEAGSDDFGAEGWRPGLHRLTDGLINDARLSDIGVEIAHLDIMRALKNRLNVI AWRKAHPEVAEQKISAPIFIVGQPRTGTTILYDLLAQDPALRAPLTWEVDEPCPVPRPETYHDDPRIART QAGIDLSEQIMPGFLAFHPMGALVGQECVRITAAEFVSMIFSVQYRLPNYYRWLLYEADHAGAYRFHRIF LQHLQSGVPGQWLLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALTHHLRGMCSDESSITECA AQSYEEIVVGLDREMALRDRGAVPPGRVIDVRYADFMKDPWTTIKDIYERLDRELRPDAEQRMREFLASH PSDGGRSRYTWSDTGLDAGAVRERVRAYQDRYGVPTEALR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5269 | - | - | 100% (390) | hypothetical protein MAV_5269 |
| M. avium 104 | MAV_4174 | - | 3e-44 | 30.26% (380) | hypothetical protein MAV_4174 |
| M. avium 104 | MAV_5164 | - | 1e-42 | 30.08% (379) | hypothetical protein MAV_5164 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3559c | - | 7e-42 | 32.35% (371) | hypothetical protein Mb3559c |
| M. gilvum PYR-GCK | Mflv_4074 | - | 1e-153 | 66.41% (390) | hypothetical protein Mflv_4074 |
| M. tuberculosis H37Rv | Rv3529c | - | 7e-42 | 32.35% (371) | hypothetical protein Rv3529c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3968 | - | 6e-48 | 33.71% (356) | putative sulfotransferase |
| M. marinum M | MMAR_0220 | - | 0.0 | 81.14% (387) | hypothetical protein MMAR_0220 |
| M. smegmatis MC2 155 | MSMEG_5930 | - | 4e-46 | 32.16% (370) | hypothetical protein MSMEG_5930 |
| M. thermoresistible (build 8) | TH_0375 | - | 6e-46 | 33.51% (370) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4091 | - | 4e-44 | 32.09% (374) | hypothetical protein MUL_4091 |
| M. vanbaalenii PYR-1 | Mvan_2268 | - | 1e-160 | 69.95% (386) | hypothetical protein Mvan_2268 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5930|M.smegmatis_MC2_155 -------------------------MGTVEDLHASATKATGLDDFGTD--
TH_0375|M.thermoresistible__bu -------------------MTPRTDVGTVEDLHASAVKACGLEDFGSD--
Mb3559c|M.bovis_AF2122/97 ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
Rv3529c|M.tuberculosis_H37Rv ----------------MTRRPDRKDVATVDELHASATKLVGLDDFGTD--
MUL_4091|M.ulcerans_Agy99 -------------------MADRTDVGTVDELHASATKLVGLDDFGSD--
MAB_3968|M.abscessus_ATCC_1997 MRAGFKAARPWPIRALNRVGNPLTGIGAAPTLDTQWLRSAARRATGLEWV
MAV_5269|M.avium_104 -------------------MSL-QDRFAPERLIAAACEEAGSDDFGAEG-
MMAR_0220|M.marinum_M -------------------MSMPQDRFKPERLIATACEEAGSDDFGADG-
Mflv_4074|M.gilvum_PYR-GCK -----------------------MNRFAPEQLIVRACEATGLDDFGDDDT
Mvan_2268|M.vanbaalenii_PYR-1 ---------------------MTAGRFDPDRLVEQACAAAGLDDFGDDGS
* . * :
MSMEG_5930|M.smegmatis_MC2_155 -DDNYREALGVLLESYQRDAHLTELGSKMSRFFLRNALVARLLSEASWKA
TH_0375|M.thermoresistible__bu -DDNYKEALAVLLDSYQREADLTELGSKMSRFFLRNALVARLVSEAAWKQ
Mb3559c|M.bovis_AF2122/97 -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
Rv3529c|M.tuberculosis_H37Rv -DDNYREALGVLLDAYQGEAGLTVLGSKMNRFFLRGALVARLLSQSAWKQ
MUL_4091|M.ulcerans_Agy99 -QDTYREALEVLLDSYRREAGLTVLGSKMNRFFLRGALVARLLSEAAWKQ
MAB_3968|M.abscessus_ATCC_1997 ADAYLDDALEVLAASLRNDAKLSFLGRKMVQVRLVGMLSTRLRLRELIRK
MAV_5269|M.avium_104 ----WRPGLHRLTDGLINDARLSDIGVEIAHLDIMRALKNRLNVIAWRKA
MMAR_0220|M.marinum_M ----WQDGLQRVTDALIHEARLSAIGVEIAHLDLMRALRNRLGVIAWRRQ
Mflv_4074|M.gilvum_PYR-GCK ----WRDGLDLVCDGLTTDARLNEIGVEIAAADLHRALTSRLHIVGWRTQ
Mvan_2268|M.vanbaalenii_PYR-1 ----WRDGLHRLCDGLVADARLNDLGVEIAAMDIHRALTSRLAIVDWRAR
.* : . :* *. :* :: : * **
MSMEG_5930|M.smegmatis_MC2_155 NPQYADVEIERPIFVTGLPRTGTTVLHRLLTADPAHQGLEMWLAEFPQPR
TH_0375|M.thermoresistible__bu YPQHADVVIERPIFVTGLPRTGTTALHRLLAADPAHQGLELWLAEFPQPR
Mb3559c|M.bovis_AF2122/97 YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
Rv3529c|M.tuberculosis_H37Rv YPEHVDVAIKRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEYPQPR
MUL_4091|M.ulcerans_Agy99 YPQYAEVPIQRPIFVTGLVRTGTTALHRLLGADPAHQGLHMWLAEFPQPR
MAB_3968|M.abscessus_ATCC_1997 NPGIAQLPVEPPIVIVGLQRTGTTLLHRLLAADPSAGSMSSWEGASPLPH
MAV_5269|M.avium_104 HPEVAEQKISAPIFIVGQPRTGTTILYDLLAQDPALRAPLTWEVDEPCPV
MMAR_0220|M.marinum_M HPEIATKAIDQPIVIVGQPRTGTTILYDLLAQDPDLRAPLTWEVDAPCPV
Mflv_4074|M.gilvum_PYR-GCK HPEIAAAPVARPIFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNPFPL
Mvan_2268|M.vanbaalenii_PYR-1 HPAIGAAPVPRPIFIVGQPRTGTTILFDLLAQDPALRPPLTWEVDNPFPP
* : **.:.* ***** *. ** ** * * *
MSMEG_5930|M.smegmatis_MC2_155 PPRETWPDNPVYQQLAASFSQHHQENPDYTGLHFMTADEVEECWQLLRQS
TH_0375|M.thermoresistible__bu PPRETWPDNPIYRQLEAQFTKAHQENPDYTGLHFMTAGEVEECWQLLRQS
Mb3559c|M.bovis_AF2122/97 PPRETWESNPLYRQLDAQFTQHHAENPGYTGLHFMAAYELEECWQLLRQS
Rv3529c|M.tuberculosis_H37Rv PPRETWESNPLYRQLDAQFTQHHAENPGYTGLHFMAAYELEECWQLLRQS
MUL_4091|M.ulcerans_Agy99 PPRETWETNPFYRQLDAQLTQHRKDNTGYTGLHFMAAYELEECWQLLRQS
MAB_3968|M.abscessus_ATCC_1997 PEQPSGAPDLRIAQAAKDERSLRYLAPQFFAIHSVEAEAPEEDVLLLDFA
MAV_5269|M.avium_104 PRPETYHDDPRIARTQAGIDLSEQIMPGFLAFHPMGALVGQECVRITAAE
MMAR_0220|M.marinum_M PAPETYLSDPRIAQTQASIELSEQIIPGFLSFHPMGAQVGQECVRITASE
Mflv_4074|M.gilvum_PYR-GCK PRLDTYTSDPRIAQTQASIEMSEQIVPGLLGHHPMGALVGQECVRIVAGQ
Mvan_2268|M.vanbaalenii_PYR-1 PEPETYDTDPRIAQTQANIEMSEQIVPGLLAHHPMGALVGQECVRITAGQ
* : : : . . . * : * :* :
MSMEG_5930|M.smegmatis_MC2_155 LHSVSYETLAHLPTYANWLA-QQDWTRPYQRHRRNLQLIGLNDAEK--RW
TH_0375|M.thermoresistible__bu VHSVSYETLAHVPSYARWLA-RQDWTKPYQRHRRNLQLIGLNDVEK--RW
Mb3559c|M.bovis_AF2122/97 LHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEK--RW
Rv3529c|M.tuberculosis_H37Rv LHSVSYEALAHVPSYADWLS-RQDWTPSYCRHRRNLQLIGLNDAEK--RW
MUL_4091|M.ulcerans_Agy99 LHSVSYETLAHLPSYAQWLA-KQDWTPSYQRHRKNLQLIGLNDAEK--RW
MAB_3968|M.abscessus_ATCC_1997 LHSQMPEVMFHVPGYAKWLA-DQDMTPAYELHRLLLQVLQWQQPRG--RW
MAV_5269|M.avium_104 FVSMIFSVQYRLPNYYRWLLYEADHAGAYRFHRIFLQHLQSGVPG---QW
MMAR_0220|M.marinum_M FTSMIYSVQYRLPSYYRWLLYEADHRGAYRFHRIFLQHLQSGVAG---QW
Mflv_4074|M.gilvum_PYR-GCK FCSMIYPTQYRMPDYYRWLLYKADHGPAYRYHRMFLQHLQSGVGGPSCQW
Mvan_2268|M.vanbaalenii_PYR-1 FTSMIFPTQYRLPDYYRWLLYDADHGPAYRYHRMFLQHLQSGVGG---RW
. * . ::* * ** * .* ** ** : :*
MSMEG_5930|M.smegmatis_MC2_155 VLKNPSHLFALDALFATYPDALVIQCHRPAETIMASMCSLSAHTTAGWSN
TH_0375|M.thermoresistible__bu VLKNPSHLFALDALFATYPDALVVQCHRPAETIMASMCSLSQHTTAGWSN
Mb3559c|M.bovis_AF2122/97 VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLAQHTTEGWST
Rv3529c|M.tuberculosis_H37Rv VLKNPSHLFALDALMATYPDALVVQTHRPVETIMASMCSLAQHTTEGWST
MUL_4091|M.ulcerans_Agy99 VLKNPSHLFALDALMASYPDALVIQTHRPVETIMASMCSLAQHTSEGWST
MAB_3968|M.abscessus_ATCC_1997 VLKTPAHLEHLDVLLRVYPGAVVVWTHRDPAQTTASSSSMLAHYQALFSD
MAV_5269|M.avium_104 LLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALTHHLRGMCSD
MMAR_0220|M.marinum_M LLKSPAHLWQLDALLAEYPDALIVQTHRDPLNVISSIAALTHHLRRMASD
Mflv_4074|M.gilvum_PYR-GCK LLKSPAHLWQLEALLAEYPDALIVQTHRDPLNVIASISALLHHLRRLASD
Mvan_2268|M.vanbaalenii_PYR-1 LLKSPAHLWQLDALVAEYPDALIVQTHRDPLNVISSISALLHHLRRLASD
:**.*:** *:.*. **.*::: ** :* .:: * *
MSMEG_5930|M.smegmatis_MC2_155 TFVGAQIGADAMDTWARGLEAFTAER--AKHDPAQFLDVDYDDFVADPLA
TH_0375|M.thermoresistible__bu TFVGAQIGADAMETWTRGLRLFNEAR--ANYDPAQFHDVEYADFVKDPIG
Mb3559c|M.bovis_AF2122/97 KFVGAQIGADAMDTWSRGLERFNAAR--AKYDSAQFYDVDYHDLIADPLG
Rv3529c|M.tuberculosis_H37Rv KFVGAQIGADAMDTWSRGLERFNAAR--AKYDSAQFYDVDYHDLIADPLG
MUL_4091|M.ulcerans_Agy99 NFVGAQIGADAMETWSRGLQPFDSAR--TNYDPAQFYDVDYRDLIADPMG
MAB_3968|M.abscessus_ATCC_1997 RVDHHELARYWLGKNAQIIDRAIAVR--AEHP-AAFVDINYTELLDDPIA
MAV_5269|M.avium_104 ESSITECAAQSYEEIVVGLDREMALRDRGAVPPGRVIDVRYADFMKDPWT
MMAR_0220|M.marinum_M ESSIAECAAQCYEEIVVGLDREMALRAGGALPAGQVIDVLYTDFINDPWS
Mflv_4074|M.gilvum_PYR-GCK DSSIPECAAQSREQIVAGLEYAVRLRDSGVPAANQIVDVHFRDFMRDPFE
Mvan_2268|M.vanbaalenii_PYR-1 ESSIPDCAAQSREQIIVGLQRAMALRDSGALAAHQVVDVHFADFMRDPFE
: . : * . *: : ::: **
MSMEG_5930|M.smegmatis_MC2_155 TVESVYRHFGMPYTDAARAAVTEVYEASRRGPRAPKHTYSLADYGLTSEA
TH_0375|M.thermoresistible__bu TVEGIYRHFGLEFTDAARDAMTRLHTESQRGPRAPRHSYSLADYGLTAES
Mb3559c|M.bovis_AF2122/97 TVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTVEM
Rv3529c|M.tuberculosis_H37Rv TVADIYRHFGLTLSDEARQAMTTVHAESQSGARAPKHSYSLADYGLTVEM
MUL_4091|M.ulcerans_Agy99 TVADIYRHFGLTLTDEARAAMAKIHAESQTGERAPKHRYSLADYGLTAEA
MAB_3968|M.abscessus_ATCC_1997 AVQRIYHAADRRLSDDALTAMRVSLQQNRQHKHG-EHRYSLAQFGLTIAE
MAV_5269|M.avium_104 TIKDIYERLDRELRPDAEQRMREFLASHPS--DGGRSRYTWSDTGLDAGA
MMAR_0220|M.marinum_M TIRGVYRKLGRELAPETEQRMRDFLRAHPG--DGGRGRYTWSDTGLDASV
Mflv_4074|M.gilvum_PYR-GCK TIRALYARLGRELEPVAEQRMRDFLAAHPG--DHAGNRYRWADTGLDAAE
Mvan_2268|M.vanbaalenii_PYR-1 TLRTLYRRLGRELDPVTEQRMRAHLAEHPG--DHGGGRYRWADTGLDAAE
:: :* . : : * :: **
MSMEG_5930|M.smegmatis_MC2_155 VKERFTGL-----------------
TH_0375|M.thermoresistible__bu VRDAFSGL-----------------
Mb3559c|M.bovis_AF2122/97 VKERFAGL-----------------
Rv3529c|M.tuberculosis_H37Rv VKERFAGL-----------------
MUL_4091|M.ulcerans_Agy99 VKERFAGF-----------------
MAB_3968|M.abscessus_ATCC_1997 VDAAYRRYIDHFAIQTERGGVRGDR
MAV_5269|M.avium_104 VRERVRAYQDRYGVPTEALR-----
MMAR_0220|M.marinum_M VRDRVRPYQDRYGVPTEQLR-----
Mflv_4074|M.gilvum_PYR-GCK VRAQVRTYQERFGVPDEVLR-----
Mvan_2268|M.vanbaalenii_PYR-1 VRDQVRAYQQRYDVPDEPLR-----
*