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MTTKKVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGDFVFRIEDTDAARDSDESYAAILDALRWLGMD WDEGPEVGGPYEPYRQSQRREIYRDVVARLLEAGEVYEAYSTPEEVEARHLAAGRNPKLGYDNYDRDLTD AQRKAFADEGRRPVLRLRMPDEDLSWNDLVRGPTTFAAGSVPDFAITRSNGDPLYTLVNPVDDALMKITH VLRGEDILPSTPRQIALYRALMRIGVAEFVPEFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLL NYLALLGWGIADDHDVFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLAPEDFTARLREYFVTH GYDTTLDDAAFAEAAALVQTRVVVLGDAWGLLKFFNDDAYEIDEKSAAKELKPESAAVLDAALSALEAVG DWTTPAIEAALKTALLEGLELKPRKAFGPIRVAVTGAAVSPPLFESMELLGRDRSLARLRAARDRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2383 | gltX | - | 100% (486) | glutamyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_6306 | gltX | 3e-35 | 38.58% (254) | glutamyl-Q tRNA(Asp) synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3016c | gltX | 0.0 | 81.61% (484) | glutamyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_4229 | gltX | 0.0 | 80.21% (480) | glutamyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv2992c | gltX | 0.0 | 81.61% (484) | glutamyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01688 | gltX | 0.0 | 77.16% (486) | glutamyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_3298c | gltX | 0.0 | 80.95% (483) | glutamyl-tRNA synthetase |
| M. marinum M | MMAR_1719 | gltX | 0.0 | 81.48% (486) | glutamyl-tRNA synthetase GltS |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2041 | gltS | 0.0 | 79.17% (480) | PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA |
| M. ulcerans Agy99 | MUL_1957 | gltX | 0.0 | 81.08% (465) | glutamyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_2133 | gltX | 0.0 | 79.71% (483) | glutamyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2383|M.smegmatis_MC2_155 ---------MTTKKVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGDFV
MAB_3298c|M.abscessus_ATCC_199 ---------MSNTKIRVRFCPSPTGTPHVGLIRTALFNWAYARHCGGDFV
Mflv_4229|M.gilvum_PYR-GCK ------------MKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGDFV
Mvan_2133|M.vanbaalenii_PYR-1 --------MTTSDVVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
TH_2041|M.thermoresistible__bu ----MTEPTDGSTKVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFV
Mb3016c|M.bovis_AF2122/97 --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
Rv2992c|M.tuberculosis_H37Rv --------MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFV
MMAR_1719|M.marinum_M ---------MTSSSVRVRFCPSPTGIPHVGMVRTALFNWAYARHTGGTFV
MUL_1957|M.ulcerans_Agy99 ------------------------------MVRTALFNWAYARHTGGTFV
MLBr_01688|M.leprae_Br4923 MTAVTSDGTPQAAKVRVRFCPSPTGVPHVGMVRTALFNWAYARHTGGTFV
::************ ** **
MSMEG_2383|M.smegmatis_MC2_155 FRIEDTDAARDSDESYAAILDALRWLGMDWDEGPEVGGPYEPYRQSQRRE
MAB_3298c|M.abscessus_ATCC_199 FRIEDTDAGRDSEESYLAILDALRWLGLDWDEGPEVGGPYEPYRQSQRKE
Mflv_4229|M.gilvum_PYR-GCK FRIEDTDAQRDSEESYLALLDALRWLGMDWDEGPEVGGPYAPYRQSQRRD
Mvan_2133|M.vanbaalenii_PYR-1 FRIEDTDSARDSEDSYLALLDALRWLGMDWDEGPEIGGPYGPYRQSQRLD
TH_2041|M.thermoresistible__bu FRIEDTDSARDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSERLH
Mb3016c|M.bovis_AF2122/97 FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
Rv2992c|M.tuberculosis_H37Rv FRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAE
MMAR_1719|M.marinum_M FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MUL_1957|M.ulcerans_Agy99 FRIEDTDAARDSEESYLALLDALRWLGLDWDEGPEVDGPYGPYRQSQRTE
MLBr_01688|M.leprae_Br4923 LRIEDTDADRDSEESYLALLDALRWLGLNWDEGPEVGGPYGPYRQSQRTD
:******: ***::** *:********::******:.*** *****:* .
MSMEG_2383|M.smegmatis_MC2_155 IYRDVVARLLEAGEVYEAYSTPEEVEARHLAAGRNPKLGYDNYDRDLTDA
MAB_3298c|M.abscessus_ATCC_199 LHREVVRKLLEAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNYDRDLTEE
Mflv_4229|M.gilvum_PYR-GCK LYLDVIRRLLAAGEAYEAFSTAEEVEARHLAAGRNPKLGYDNFDRDLTEE
Mvan_2133|M.vanbaalenii_PYR-1 IYTDVIERLLAAGEAYEAFSTAEEVEARHIAAGRNPKLGYDNYDRDLTEE
TH_2041|M.thermoresistible__bu IYRDVIERLLESGAAYESFSTPEEVEARHRAAGRNPKLGYDNFDRDLTEE
Mb3016c|M.bovis_AF2122/97 IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
Rv2992c|M.tuberculosis_H37Rv IYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA
MMAR_1719|M.marinum_M IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MUL_1957|M.ulcerans_Agy99 IYHDVVAKLLTAGEAYYAFSTPEEVEARHIAAGRNPKLGYDNFDRQLTDS
MLBr_01688|M.leprae_Br4923 IYREVVAKLLATGEAYYAFSTPEEVENRHLAAGRNPKLGYDNFDRDLTDA
:: :*: :** :* .* ::**.**** ** ************:**.**:
MSMEG_2383|M.smegmatis_MC2_155 QRKAFADEGRRPVLRLRMPDEDLSWNDLVRGPTTFAAGSVPDFAITRSNG
MAB_3298c|M.abscessus_ATCC_199 QRAAFRAEGRDPVVRLRMPDHDITWNDLVRGETTFAAGVVPDFALTRGNG
Mflv_4229|M.gilvum_PYR-GCK QRAAFRAEGRQPVVRLRMPDADMTWVDLVRGETTFPVGSVPDFALTRGSG
Mvan_2133|M.vanbaalenii_PYR-1 QRAAFRAEGRRPVVRLRMPDTDLTWVDLVRGETTFPAGSVPDFALTRGNG
TH_2041|M.thermoresistible__bu QRRAYRAEGRRPVIRLKMPDRDIGWRDLVRGETTFPAGTLADFALTRSNG
Mb3016c|M.bovis_AF2122/97 QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
Rv2992c|M.tuberculosis_H37Rv QRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASG
MMAR_1719|M.marinum_M QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MUL_1957|M.ulcerans_Agy99 QRAAYLAEGRKPVVRLRMPDTDLAWHDLVRGPTTFAAGSVPDFALTRATG
MLBr_01688|M.leprae_Br4923 QFSAYLAEGRKPVVRLRMPDEDISWDDLVRGTTTFAVGTVPDYVLTRASG
* *: *** **:**:*** *: * ***** .**..* :.*:.:**..*
MSMEG_2383|M.smegmatis_MC2_155 DPLYTLVNPVDDALMKITHVLRGEDILPSTPRQIALYRALMRIGVAEFVP
MAB_3298c|M.abscessus_ATCC_199 DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEAMIRIGVTDSIP
Mflv_4229|M.gilvum_PYR-GCK DPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQLALYAALIRIGVTDMTP
Mvan_2133|M.vanbaalenii_PYR-1 EPLYPLVNPVDDALMKITHVLRGEDLLPSTPRQLALYGALIRIGVADTTP
TH_2041|M.thermoresistible__bu EPLYTLVNPVDDALMKITHVLRGEDLLPSTPRQIALYEALMAIGVADTVP
Mb3016c|M.bovis_AF2122/97 DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
Rv2992c|M.tuberculosis_H37Rv DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIP
MMAR_1719|M.marinum_M DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMRIGIAERVP
MUL_1957|M.ulcerans_Agy99 DPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQIALYQALMCIGIAERVP
MLBr_01688|M.leprae_Br4923 DPLYTLVNPCDDALMKITHVLRGEDLLSSTPRQVALYQALIRIGMAERIP
:***.**** ***************:*.*****:**: *:: **::: *
MSMEG_2383|M.smegmatis_MC2_155 EFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWGIA
MAB_3298c|M.abscessus_ATCC_199 AFAHLPSVLGEGTKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
Mflv_4229|M.gilvum_PYR-GCK QFAHLPSVLGEGNKKLSKRDPQSNLFLHRERGFIPEGLLNYLALLGWSIA
Mvan_2133|M.vanbaalenii_PYR-1 QFAHLPSVLGEGNKKLSKRDPQSNLFLHRDRGFIPEGLLNYLALLGWSIA
TH_2041|M.thermoresistible__bu EFGHLPSVLGEGNKKLSKRDPQSNLFAHRERGFIPEGLLNYLALLGWGLA
Mb3016c|M.bovis_AF2122/97 KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
Rv2992c|M.tuberculosis_H37Rv KFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIA
MMAR_1719|M.marinum_M EFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MUL_1957|M.ulcerans_Agy99 EFAHLPTVLGEETKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
MLBr_01688|M.leprae_Br4923 EFGHFPSVLGEGTKKLSKREPQSNLFAHRDRGFIPEGLLNYLALLGWAIA
*.*:*:**** .******:****** **:*****************.:*
MSMEG_2383|M.smegmatis_MC2_155 DDHDVFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLAPEDFTA
MAB_3298c|M.abscessus_ATCC_199 DDHDIFSLAEMVTAFDVTDVNSNPARFDQKKADAINAEHIRLLAPEEFVT
Mflv_4229|M.gilvum_PYR-GCK DDRDIFSVQEMVAAFDVADVNSNPARFDQKKADALNAEHIRRLDEAEFVR
Mvan_2133|M.vanbaalenii_PYR-1 DDHDIFSLEEMVAAFDVADVNSSPARFDQKKADALNAEHIRLLDEAEFAR
TH_2041|M.thermoresistible__bu DDRDVFTLDEMVAAFDVTDVNSNPARFDQKKAEALNAEHIRMLDEADFAE
Mb3016c|M.bovis_AF2122/97 DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
Rv2992c|M.tuberculosis_H37Rv DDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTV
MMAR_1719|M.marinum_M DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MUL_1957|M.ulcerans_Agy99 DDHDLFSLDEMVAAFDVADVNSNPARFDQKKADAINAEHIRMLDVADFTA
MLBr_01688|M.leprae_Br4923 DDHDLFSLDEMVAAFDVVDVNSNPARFDQKKADAVNAEHIRMLDSEDFAG
**:*:* : ***:****.****.*********:*:****** * :*.
MSMEG_2383|M.smegmatis_MC2_155 RLREYFVTHGYDTTLD----DAAFAEAAALVQTRVVVLGDAWGLLKFFND
MAB_3298c|M.abscessus_ATCC_199 RLRTYFAAHGHELGLD----ESAFAVAADLVQTRIVVLGDAWGLLKFLND
Mflv_4229|M.gilvum_PYR-GCK RLADYFSTHGYDTGLD----DARFAEAAALVQTRIVVLGDAWDLLKFLDE
Mvan_2133|M.vanbaalenii_PYR-1 RLGAYFATHGHRTGLD----DAQFAEAARLVQTRIVVLGDAWELLKFLDD
TH_2041|M.thermoresistible__bu RLKAYFAAHGHDTGLD----DEQFAMAARLAQTRIVVLADAWDLLKFLDD
Mb3016c|M.bovis_AF2122/97 RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
Rv2992c|M.tuberculosis_H37Rv RLRDHLDTHGHHIALD----EAAFAAAAELVQTRIVVLGDAWELLKFFND
MMAR_1719|M.marinum_M RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MUL_1957|M.ulcerans_Agy99 RLRAYLDTHGHQLALD----DAAFAVAAELVQTRIVVLEDAWALLKFLND
MLBr_01688|M.leprae_Br4923 RLRDYFTTHGYHIALDPANYEAGFVAAAQLVQTRIVVLGDAWDLLKFLND
** :: :**: ** : *. ** *.***:*** *** ****:::
MSMEG_2383|M.smegmatis_MC2_155 DAYEIDEKSAAKELKPESAAVLDAALSALEAVGDWTTPAIEAALKTALLE
MAB_3298c|M.abscessus_ATCC_199 DAYAIDPGAARKELGEASLPVLDAAIGALESLEAWTTPAIEGALKSALIE
Mflv_4229|M.gilvum_PYR-GCK SSFALDEKSAGKELKDTAVPVLTAALAALKGVGEWTTAQIEDALKVALID
Mvan_2133|M.vanbaalenii_PYR-1 ASFTLDEKSAAKELKAEAVPVLGAALEALRGVEAWDTAAIEEALKGALID
TH_2041|M.thermoresistible__bu DSFELDEKAARKELKAEAVAVLDAALTALEALDEWRTETIEIALKAALLE
Mb3016c|M.bovis_AF2122/97 DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
Rv2992c|M.tuberculosis_H37Rv DQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIE
MMAR_1719|M.marinum_M DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIE
MUL_1957|M.ulcerans_Agy99 DRYAIDPKAAAKELGPDAGPVLDAAIAALDGAADWTTADIEAALKTALIG
MLBr_01688|M.leprae_Br4923 DEYSIDSKAAAKELDADAGPVLDVACAVLDSLVDWTTASIEDVLKVALIE
: :* :* *** . .** .* .* . * : ** .** **:
MSMEG_2383|M.smegmatis_MC2_155 GLELKPRKAFGPIRVAVTGAAVSPPLFESMELLGRDRSLARLRAAR----
MAB_3298c|M.abscessus_ATCC_199 GLELKPRKAFGPLRVAVTGATVSPPLFESMELLGSGRTLTRLRNARSWEN
Mflv_4229|M.gilvum_PYR-GCK GLELKPRKAFGPVRVAVTGSSISPPLFESLELLGRDRSLERLRAGRDHAA
Mvan_2133|M.vanbaalenii_PYR-1 RLELKPRKAFGPVRVAATGSSVSPPLFESLELLGRDRSLARLQAGRDHAA
TH_2041|M.thermoresistible__bu GLGLKPRKAFGPVRVAATGATVSPPLFESLELLGRERTLQRLRAGRDHAA
Mb3016c|M.bovis_AF2122/97 GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
Rv2992c|M.tuberculosis_H37Rv GLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVG
MMAR_1719|M.marinum_M GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MUL_1957|M.ulcerans_Agy99 GMALKPRKAFGPIRVAATGTTVSPPLFESLELLGRERSLGRLRSARDQVG
MLBr_01688|M.leprae_Br4923 GLGLKPRKVFGPIRVAATGALVSPPLFESLELLGRARSLQRLSAARARVT
: *****.*.*:***.**: :*******:**** *:: ** .*
MSMEG_2383|M.smegmatis_MC2_155 ---DRV---
MAB_3298c|M.abscessus_ATCC_199 GVGDQTDSG
Mflv_4229|M.gilvum_PYR-GCK AAVTMDA--
Mvan_2133|M.vanbaalenii_PYR-1 AAAAPQG--
TH_2041|M.thermoresistible__bu AAESTGG--
Mb3016c|M.bovis_AF2122/97 HA-------
Rv2992c|M.tuberculosis_H37Rv HA-------
MMAR_1719|M.marinum_M SP-------
MUL_1957|M.ulcerans_Agy99 SP-------
MLBr_01688|M.leprae_Br4923 SA-------