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MLISRMSVRSASMSVMGDVFIGSEAITAGRLTRHELQRWYQPMFRGVYVSRRSVPTLWDRTVGAWLATRR HGVIAGNAASALHGAQWVDVDVAIELISPTTRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRH LSRGEAVARLDALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWLRLLLIDAGLPV PTTQIPVVHRWRNVGVLDMGWEKYMVAAEYDGDQHRSDRGRYVKDQRRLRKLAELGWIVIRVIAEDNPDD VVNRVRAALLARGWRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3741c | - | - | 100% (296) | hypothetical protein Mb3741c |
| M. bovis AF2122 / 97 | Mb1102 | - | 2e-70 | 51.11% (270) | hypothetical protein Mb1102 |
| M. bovis AF2122 / 97 | Mb3546 | - | 8e-67 | 49.63% (270) | hypothetical protein Mb3546 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4812 | - | 9e-87 | 54.45% (281) | hypothetical protein Mflv_4812 |
| M. tuberculosis H37Rv | Rv3714c | - | 1e-171 | 100.00% (296) | hypothetical protein Rv3714c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2184 | - | 4e-86 | 57.19% (278) | hypothetical protein MAB_2184 |
| M. marinum M | MMAR_0375 | - | 1e-95 | 60.69% (290) | hypothetical protein MMAR_0375 |
| M. avium 104 | MAV_4752 | - | 8e-74 | 53.43% (277) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_0256 | - | 3e-92 | 60.00% (280) | hypothetical protein MSMEG_0256 |
| M. thermoresistible (build 8) | TH_4125 | - | 6e-62 | 48.03% (279) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 1e-93 | 59.31% (290) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 7e-88 | 58.30% (283) | hypothetical protein Mvan_5526 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3741c|M.bovis_AF2122/97 MLISRMSVRSASMSVMGDV-FIGSEAITAGRLTRHELQRWYQPMFRGVYV
Rv3714c|M.tuberculosis_H37Rv MLISRMSVRSASMSVMGDV-FIGSEAITAGRLTRHELQRWYQPMFRGVYV
MMAR_0375|M.marinum_M -----MDAREARAARSEDV-FVGSEAVRRGRLSPYRLRTEFRAIYPDVYL
MUL_4737|M.ulcerans_Agy99 -----MDAREARAARSEDV-FVGSGAVRRGRLSPYRLRTEFRAIYPDVYL
Mflv_4812|M.gilvum_PYR-GCK ---------------MGDI-IIGTEAVANGTVTRHQLQRWYRPIFTNIHA
MSMEG_0256|M.smegmatis_MC2_155 ---------------MRQL-IVGSQALAEGTVTEHELRRWYRRMYRDIYI
MAB_2184|M.abscessus_ATCC_1997 ---------------MAAV-FVGSEAVSAGQLTRHELQRFYRPIFRGVYL
Mvan_5526|M.vanbaalenii_PYR-1 ------------MPGMGEV-ILGGEAVRAGVVTRHELARWYTPLYRGVFV
MAV_4752|M.avium_104 ---------------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYL
TH_4125|M.thermoresistible__bu ---------------MREV-FIGSAALRGGGLTRGRLRWNYRAMYPDVYV
.:* : * :. .* : :: .:.
Mb3741c|M.bovis_AF2122/97 SRRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISP
Rv3714c|M.tuberculosis_H37Rv SRRSVPTLWDRTVGAWLATRRHGVIAGNAASALHGAQWVDVDVAIELISP
MMAR_0375|M.marinum_M PAHAAPSFRTRCKAAWLWTGRRGVLAGLAAAGLHGSDWIGDDEPVELIWR
MUL_4737|M.ulcerans_Agy99 PAHAAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWR
Mflv_4812|M.gilvum_PYR-GCK PRGPAPTLGDRAVGAWLYSKRHGIVTGLAAAALHGSRWIDADVDIELIYK
MSMEG_0256|M.smegmatis_MC2_155 PAGYTPTLIDHIDGAWLRSGRQGIVAGVAASALFGADWVDAGIAVEMVWD
MAB_2184|M.abscessus_ATCC_1997 PKSAEPTLRDRTVAAWLASGRRGVVAGLAASNLHGASWVDHDVPIELVGV
Mvan_5526|M.vanbaalenii_PYR-1 RKGVEVTLRDRAVGAWLATGRKGVIAGLAAAALHGAAWIDADIPIEVAGV
MAV_4752|M.avium_104 PAQVEPTLPLRIRAAWLWSGRTAVIAGAAAAAVHGAAWIPDAVPIELIHH
TH_4125|M.thermoresistible__bu AKDRPPTLRQFIVGAWLWSGREGVITGRAAAALHGAKYVDDATPIELIWK
:: .*** : * .:: * **: :.*: :: :*:
Mb3741c|M.bovis_AF2122/97 TTRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVAR
Rv3714c|M.tuberculosis_H37Rv TTRPQHGLVIRRETLCDDEITRVVGLPVTTLARTAYDLGRHLSRGEAVAR
MMAR_0375|M.marinum_M NPHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVAR
MUL_4737|M.ulcerans_Agy99 NPHPPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVAR
Mflv_4812|M.gilvum_PYR-GCK CPRPPSGIVARNDRIDPDEWQSIDGLPVATAARTAFDLGRYRPEHDALAR
MSMEG_0256|M.smegmatis_MC2_155 NTRPPRGIIARDERTEDDEITTAQCITVTTPARTAFDLGRHLRRSEALAR
MAB_2184|M.abscessus_ATCC_1997 KCRQQEGLIARNERIGADEITRISGLPVTHRVRTAFDLGRYQPRTRAMGC
Mvan_5526|M.vanbaalenii_PYR-1 KRRSHAGLITRSEVIATDEIVRRAGLPVTSRTRTAFDLGRQLDRAEALAR
MAV_4752|M.avium_104 NTRAPDGVLIRRDGLCPGETQICDGLAVTTPERTAFDIGRRGAVRSAVVR
TH_4125|M.thermoresistible__bu AGRPPPRIIVRNERLDAADVTTVDDMLVTTPARTAFDLARHLPRDAAVRH
: :: * : : : *: ***:*:.* ::
Mb3741c|M.bovis_AF2122/97 LDALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWL
Rv3714c|M.tuberculosis_H37Rv LDALMRATPFSRDDVLLLAKRHAGARGVRRLRDVLPLVDGGAASPKETWL
MMAR_0375|M.marinum_M LDALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRETWL
MUL_4737|M.ulcerans_Agy99 LDALMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWL
Mflv_4812|M.gilvum_PYR-GCK LDALMAVRPYSVEDVLLLTKRYKGARGVARLKALLPFVDGGAQSPRESWW
MSMEG_0256|M.smegmatis_MC2_155 MDALMRATAFSPDDVAALAERYRGARGIRQLRELLPLVDGGAESPRETRT
MAB_2184|M.abscessus_ATCC_1997 LDALMRNQVFALDEVAGLSQRYPKVRGVRQLRELLPLIDAGAQSPRESLI
Mvan_5526|M.vanbaalenii_PYR-1 LDALMWNQPFSIDEVAELADRRPRVPGVGQLRDLLPLIDGGAASPRQSRL
MAV_4752|M.avium_104 LDSLARATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRESYL
TH_4125|M.thermoresistible__bu LDALAGATGVCAADVLPLADRYRRARGLPRARVALDLMDGGAQSPRETRL
:*:* :* :: *: : . * ::* ** **:::
Mb3741c|M.bovis_AF2122/97 RLLLIDAGLPVPTTQIPVVHR-WRNVGVLDMGWEKYMVAAEYDGDQHRSD
Rv3714c|M.tuberculosis_H37Rv RLLLIDAGLPVPTTQIPVVHR-WRNVGVLDMGWEKYMVAAEYDGDQHRSD
MMAR_0375|M.marinum_M RMVLIDAGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFD
MUL_4737|M.ulcerans_Agy99 RMVLIDAGLPVPVTQIPVHQN-WRLVAVLDMGWQKYQVAAEYDGDQHRFD
Mflv_4812|M.gilvum_PYR-GCK RKLVLDSGFPPPRTQIPVVDENGYHVRTLDFGWEGPNVAVEYDGDQHQSD
MSMEG_0256|M.smegmatis_MC2_155 RLLLFDAGFPRPTTQIPAVDERGRLVRMLDMGWEEFMVAAEYDGDQHRTE
MAB_2184|M.abscessus_ATCC_1997 RLQLRDAGLPRAQTQVPVFDG-YTPIAFLDIGWPQYLVAVEYDGDHHRRD
Mvan_5526|M.vanbaalenii_PYR-1 RLWLLDCGFPRPQTQIPVLEG-SRPVAFLDMGWPEYQVAVEYDGDHHRKN
MAV_4752|M.avium_104 RLLLIDAGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHRTD
TH_4125|M.thermoresistible__bu RLILVDDGLPRPRTQIGVS--DGVNEAFIDMGWDEPMVGLDYEGAHHSAD
* : * *:* . **: . :*:** *. :*:* :* :
Mb3741c|M.bovis_AF2122/97 RGRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP--
Rv3714c|M.tuberculosis_H37Rv RGRYVKDQRRLRKLAELGWIVIRVIAEDNPDDVVNRVRAALLARGWRP--
MMAR_0375|M.marinum_M RRQYARDQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET-
MUL_4737|M.ulcerans_Agy99 RRQYAREQWRLRKLDELGWIVIRVIAGDAPEDVVRRVRQALARRGHRET-
Mflv_4812|M.gilvum_PYR-GCK RAQYLKDRRVMPALRRLGWHVTTVVKEDDPVAVIQTLSAAMRARGWRGSI
MSMEG_0256|M.smegmatis_MC2_155 RARYVKDIRVWPKLRELGWDVIRVIKEDRDSDVLQRVHRALVARGWDGKL
MAB_2184|M.abscessus_ATCC_1997 RRQYVKDLARLRMLEERGWTVIRVIAEESPGAWIARTTAALRSRGCHIEI
Mvan_5526|M.vanbaalenii_PYR-1 RDQYVKDIARLRMLEALGWIVIRVIAEDRPAHWLERTEAALQSRGCRLAA
MAV_4752|M.avium_104 RRQYVKDIRRLEMLEQLGWVIVRVVAEDRPADIVRRVRAALAKSGVAPRL
TH_4125|M.thermoresistible__bu RRQYVHDIGRAELIVGQGWLDIRVVAEHSRRFILHRTREAFARRGWHLPK
* :* :: : ** *: . : *: *
Mb3741c|M.bovis_AF2122/97 -----------------------
Rv3714c|M.tuberculosis_H37Rv -----------------------
MMAR_0375|M.marinum_M -----------------------
MUL_4737|M.ulcerans_Agy99 -----------------------
Mflv_4812|M.gilvum_PYR-GCK QIPRYAYTTRFRAEIASRQEKCE
MSMEG_0256|M.smegmatis_MC2_155 LP-------RLRSLQDRRISRPT
MAB_2184|M.abscessus_ATCC_1997 D----------EMQRSTRPFAA-
Mvan_5526|M.vanbaalenii_PYR-1 T----------ELQLFVRTLAA-
MAV_4752|M.avium_104 SV---------------------
TH_4125|M.thermoresistible__bu PV---------------------