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VGHVIPAPGNGQTFLGPDHRVRAWQRLGNEQFDVIVIGGGVVGAGAALDAATRGLKVALVEARDFASGTS SRSSKMFHGGLRYLEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTNRGWERPYIAAGIFLYDQL GGAKSVPAQKHLTRSGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYSAVVRTSTQVVALL REGDRVTGVRVRDSENGEVTEVRGHVVVNATGVWTDEIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVA IILRTEKSVLFVIPWGTHWIIGTTDTDWHLDLAHPAATKADIDYILGHVNKVLATPLTHDDIDGVYAGLR PLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAEDAIDAAAEFIPTRVAPSITERVPLMGAD GYFALINQTQSVGAHYGLHPYRVRHLLDRYGSLIGEVLKLASDLAAVRPDLLEPITDAPVYLKVEAAYAA AAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPLLGWSAEDVDREVDTYLARVEAEVLSQTQPD DESADALRAAAPEARAEILEPVPLK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1620 | - | - | 100% (585) | FAD dependent oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_3759 | - | 3e-65 | 36.64% (535) | FAD dependent oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_5513 | - | 9e-08 | 28.76% (233) | FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3330c | glpD2 | 0.0 | 85.37% (588) | glycerol-3-phosphate dehydrogenase |
M. gilvum PYR-GCK | Mflv_4821 | - | 0.0 | 94.01% (584) | FAD dependent oxidoreductase |
M. tuberculosis H37Rv | Rv3302c | glpD2 | 0.0 | 85.37% (588) | glycerol-3-phosphate dehydrogenase |
M. leprae Br4923 | MLBr_00713 | glpD | 0.0 | 82.82% (588) | putative glycerol-3-phosphate dehydrogenase |
M. abscessus ATCC 19977 | MAB_3655c | - | 0.0 | 85.02% (574) | glycerol-3-phosphate dehydrogenase |
M. marinum M | MMAR_1225 | glpD2 | 0.0 | 85.96% (570) | glycerol-3-phosphate dehydrogenase GlpD2 |
M. avium 104 | MAV_4278 | - | 0.0 | 85.40% (582) | glycerol-3-phosphate dehydrogenase 2 |
M. smegmatis MC2 155 | MSMEG_1736 | - | 0.0 | 91.71% (579) | glycerol-3-phosphate dehydrogenase 2 |
M. thermoresistible (build 8) | TH_1838 | glpD2 | 0.0 | 88.87% (584) | PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD2 |
M. ulcerans Agy99 | MUL_2667 | glpD2 | 0.0 | 85.96% (570) | glycerol-3-phosphate dehydrogenase GlpD2 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_1620|M.vanbaalenii_PYR-1 MGHVIPAPGNGQTF----LGPDHRVRAWQRLGNEQFDVIVIGGGVVGAGA Mflv_4821|M.gilvum_PYR-GCK MSDPIPAPGNGETF----LGPDERARAWQRLGSEQFDVIVIGGGIVGAGA MSMEG_1736|M.smegmatis_MC2_155 MTVPKPAPGDGQTF----LGPQQRAQAWEQLGNQQFDVVVIGGGVVGAGA TH_1838|M.thermoresistible__bu VSHPILRPGHGPTL----LGPEQRQRAWDRLGSEQFDVVVIGGGVVGSGA MMAR_1225|M.marinum_M MSNPTDASQRDQTGPAGSLGPEQRALAWERLGAEQFDVVVIGGGVVGSGC MUL_2667|M.ulcerans_Agy99 MSNPTDASQRDQTGPADSLGPEQRALAWERLGAEQFDVVVIGGGVVGSGC Mb3330c|M.bovis_AF2122/97 MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGC Rv3302c|M.tuberculosis_H37Rv MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGC MLBr_00713|M.leprae_Br4923 MTDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGC MAV_4278|M.avium_104 MSDPIHALG-EPGSPASALGPRQRAAAWDRLGAEQFDVVVIGGGVVGSGC MAB_3655c|M.abscessus_ATCC_199 MSDATSPSGSSGPT-YTFLGPEARSLNWERLGSEQFDVIVIGGGVVGAGS : *** * *.::* :****:*****:**:*. Mvan_1620|M.vanbaalenii_PYR-1 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Mflv_4821|M.gilvum_PYR-GCK ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MSMEG_1736|M.smegmatis_MC2_155 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL TH_1838|M.thermoresistible__bu ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MMAR_1225|M.marinum_M ALDAATRGLKVALIEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MUL_2667|M.ulcerans_Agy99 ALDAATRGLKVALIEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Mb3330c|M.bovis_AF2122/97 ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Rv3302c|M.tuberculosis_H37Rv ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MLBr_00713|M.leprae_Br4923 ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MAV_4278|M.avium_104 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MAB_3655c|M.abscessus_ATCC_199 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVQEAL *************:****:***************************:*** Mvan_1620|M.vanbaalenii_PYR-1 HERELSLTTLAPHLVKPLPFLFPLTNRGWERPYIAAGIFLYDQLGGAKSV Mflv_4821|M.gilvum_PYR-GCK HERELSLTTLAPHLVKPLPFLFPLTNRVWERPYIAAGIFLYDQLGGAKSV MSMEG_1736|M.smegmatis_MC2_155 HERELSLTTLAPHLVKPLPFLFPLTNRWWERPYVAAGIFLYDQLGGAKSV TH_1838|M.thermoresistible__bu HERELSLTTLAPHLVKPLPFLYPLTRRWWERPYVALGIFLYDQLGGARSL MMAR_1225|M.marinum_M FERELSLTTLAPHLVKPLPFLFPLTKRGWERPYIAAGIFLYDRLGGAKSV MUL_2667|M.ulcerans_Agy99 FERELSLTTLAPHLVKPLPFLFPLTKRGWERPYIAAGIFLYDRLGGAKSV Mb3330c|M.bovis_AF2122/97 YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV Rv3302c|M.tuberculosis_H37Rv YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV MLBr_00713|M.leprae_Br4923 YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV MAV_4278|M.avium_104 YERELSLTTLAPHLVKPMPFLFPLTNRLWERPYIAAGIFLYDRLGGAKSV MAB_3655c|M.abscessus_ATCC_199 RERELSLSTLAPHLVKPLPFLFPLTSRWWERPYVAAGIFLYDQMGGAKSV ******:*********:***:*** * *****:* ******::***:*: Mvan_1620|M.vanbaalenii_PYR-1 PAQKHLTRSGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY Mflv_4821|M.gilvum_PYR-GCK PPQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY MSMEG_1736|M.smegmatis_MC2_155 PAQKHLTKAGALRLAPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY TH_1838|M.thermoresistible__bu PAQKHLTKAGALRLAPGLRRDSLIGGIRYYDTVVDDARHTLTVARTAAHY MMAR_1225|M.marinum_M PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTASHY MUL_2667|M.ulcerans_Agy99 PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTASHY Mb3330c|M.bovis_AF2122/97 PAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY Rv3302c|M.tuberculosis_H37Rv PAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY MLBr_00713|M.leprae_Br4923 PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTLTVARTAAHY MAV_4278|M.avium_104 PAQKHLTRAGALRLCPGLKRSALIGGIRYYDTIVDDARHTLTVARTAAHY MAB_3655c|M.abscessus_ATCC_199 PAQKHLTRAGALRLAPGLKRNSLIGGIRYYDTVVDDARHTMTVARTAAHY *.*:*:*::*****.***:*.:**********:*******:******:** Mvan_1620|M.vanbaalenii_PYR-1 SAVVRTSTQVVALLREGDRVTGVRVRDSENGEVTEVRGHVVVNATGVWTD Mflv_4821|M.gilvum_PYR-GCK GAVVRTSTQVVALLREGDRVTGVQVRDSEDGRVTDVRGHVVVNATGVWTD MSMEG_1736|M.smegmatis_MC2_155 GAVVRSSTQVVALLREGDRVTGVRVRDSEDGSVTEVNGHVVVNATGVWTD TH_1838|M.thermoresistible__bu GAVIRSSTQVVALLREGDRVTGVTVRDSETGAVTDVHGHVVVNATGVWTD MMAR_1225|M.marinum_M GAVVRCSTQVVALLREGDRVVGVRVRDSEDGSITEVRGHVVVNATGVWTD MUL_2667|M.ulcerans_Agy99 GAVVRCSTQVVALLREGDRVVGVRVRDSEDGSITEVRGHVVVNATGVWTD Mb3330c|M.bovis_AF2122/97 GAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTD Rv3302c|M.tuberculosis_H37Rv GAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTD MLBr_00713|M.leprae_Br4923 GAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHVVVNATGVWTD MAV_4278|M.avium_104 GVVVRNSTQVVALLREGDRVTGVRVRDSEDGSVTEVRGHVVVNATGVWTD MAB_3655c|M.abscessus_ATCC_199 GAVVRASTQVVSLLREGDRVTGVLVRDTESGAETEVRGHVVINATGVWTD ..*:* *****:******** ** ***:* * :::.****:******** Mvan_1620|M.vanbaalenii_PYR-1 EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG Mflv_4821|M.gilvum_PYR-GCK EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG MSMEG_1736|M.smegmatis_MC2_155 EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG TH_1838|M.thermoresistible__bu EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG MMAR_1225|M.marinum_M EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFIIPWG MUL_2667|M.ulcerans_Agy99 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFIIPWG Mb3330c|M.bovis_AF2122/97 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG Rv3302c|M.tuberculosis_H37Rv EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG MLBr_00713|M.leprae_Br4923 EIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWG MAV_4278|M.avium_104 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAIILRTEKSVMFVIPWG MAB_3655c|M.abscessus_ATCC_199 EIQALSKTRGRFRVTASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG ******* ****:* .*****:*********:**:****:***:*:**** Mvan_1620|M.vanbaalenii_PYR-1 THWIIGTTDTDWHLDLAHPAATKADIDYILGHVNKVLATPLTHDDIDGVY Mflv_4821|M.gilvum_PYR-GCK THWIIGTTDTDWNLDLAHPAATKADIDYILGHVNKVLATPLTHDDIDGVY MSMEG_1736|M.smegmatis_MC2_155 THWIIGTTDTDWNLDLAHPAATKADIDYILGHVNTVLATPLTHDDIDGVY TH_1838|M.thermoresistible__bu THWIIGTTDTDWNLDLAHPAATKADIDYILGQVNRALATPLTHADIDGVY MMAR_1225|M.marinum_M SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY MUL_2667|M.ulcerans_Agy99 SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY Mb3330c|M.bovis_AF2122/97 SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY Rv3302c|M.tuberculosis_H37Rv SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY MLBr_00713|M.leprae_Br4923 NHWIIGTTDTDWNLDLAHPAATKADIDYILQTVNTVLATPLTHADIDGVY MAV_4278|M.avium_104 SHWIIGTTDTDWDLDLAHPAATKADIDYILSTVNTVLAIPLTHADIDGVY MAB_3655c|M.abscessus_ATCC_199 NHWIIGTTDTEWNLDLAHPAATKVDIDYILDHVNTVLATPLTHNDIDGVY .*********:*.**********.****** ** .** **** ****** Mvan_1620|M.vanbaalenii_PYR-1 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAEDAID Mflv_4821|M.gilvum_PYR-GCK AGLRPLLAGESEETSKLSREHAVAVPSPGLVAIAGGKYTTYRVMAEDAID MSMEG_1736|M.smegmatis_MC2_155 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAADAID TH_1838|M.thermoresistible__bu AGLRPLLAGESEETSKLSREHAVAVPAPGLIAIAGGKYTTYRVMGEDAID MMAR_1225|M.marinum_M AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID MUL_2667|M.ulcerans_Agy99 AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID Mb3330c|M.bovis_AF2122/97 AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID Rv3302c|M.tuberculosis_H37Rv AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID MLBr_00713|M.leprae_Br4923 AGLRPLLAGESDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAID MAV_4278|M.avium_104 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAADAID MAB_3655c|M.abscessus_ATCC_199 AGLRPLLAGENDDTSKLSREHAVAVAAPGLVAIAGGKYTTYRVMASDAVD **********.::****:*******. .**:*************. **:* Mvan_1620|M.vanbaalenii_PYR-1 AAAEFIPTRVAPSITERVPLMGADGYFALINQTQSVGAHYGLHPYRVRHL Mflv_4821|M.gilvum_PYR-GCK AAAEFIPTRVAPSITEKVPLMGADGYFALINQTQSVGTYYDLHPYRVRHL MSMEG_1736|M.smegmatis_MC2_155 AAAEFVPTRVAPSITEKVPLMGADGYFALINQTEHVGRQYGLHPYRVRHL TH_1838|M.thermoresistible__bu AAAEFIPARVAPSITEKVPLLGADGYFALINQTETVGAHYGLHPYRVRHL MMAR_1225|M.marinum_M AAVQFVPARVAPSITEKVSLLGADGYFALVNQVEHVGEMVGLHPYRVRHL MUL_2667|M.ulcerans_Agy99 AAVQFVPARVAPSITEKVSLLGADGYFALVNQVEHVGEMVGLHPYRVRHL Mb3330c|M.bovis_AF2122/97 AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHL Rv3302c|M.tuberculosis_H37Rv AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHL MLBr_00713|M.leprae_Br4923 AAVAFVPARVAPSITEKVGLLGADGYFALINQVEHVAALQGLHPYRVRHL MAV_4278|M.avium_104 AAAQFIPARVAPSITEKVSLLGADGYFALINQAEHVAQLRGLHPYRVRHL MAB_3655c|M.abscessus_ATCC_199 MASEFVPARVAPSITEKVPLLGADGYFALINQTEHVGETYGLHPYRVRHL * *:*:********:* *:********:**.: *. .********* Mvan_1620|M.vanbaalenii_PYR-1 LDRYGSLIGEVLKLASDLAAVRPDLLEPITDAPVYLKVEAAYAAAAEGAL Mflv_4821|M.gilvum_PYR-GCK LDRYGSLIGEVLKLAED----NPDLLNPITEAPVYLKVEAAYAAAAEGAL MSMEG_1736|M.smegmatis_MC2_155 LDRYGSLIGEVLALADG----KPELLEPITEAPVYLKVEAAYAAAAESAL TH_1838|M.thermoresistible__bu LDRYGSLIGEVLQMAGRDGAGRPDLLEPITDAPVYLKVEAWYAAAAEGAL MMAR_1225|M.marinum_M LDRYGSLINEVLELAAD----DPDLLTPIKEAPGYLKVEALYAVTAEGAL MUL_2667|M.ulcerans_Agy99 LDRYGSLINEVLELAAD----DPDLLTPIKEAPGYLKVEALYAVTAEGAL Mb3330c|M.bovis_AF2122/97 LDRYGSLISDVLAMAAS----DPSLLSPITEAPGYLKVEAAYAAAAEGAL Rv3302c|M.tuberculosis_H37Rv LDRYGSLISDVLAMAAS----DPSLLSPITEAPGYLKVEAAYAAAAEGAL MLBr_00713|M.leprae_Br4923 LDRYGALIGDVLALAAE----APDLLSPIQEAPGYLKVEARYAVTAEGAL MAV_4278|M.avium_104 LDRYGSLIGDVLALAAD----RPDLLNPITEAPGYLRVEALYAVTAEGAL MAB_3655c|M.abscessus_ATCC_199 LDRYGSLIGEVLACAGT----DHSLLQPITKAPMYLKVEARYAVAAEGAL *****:**.:** * .** ** .** **:*** **.:**.** Mvan_1620|M.vanbaalenii_PYR-1 HLEDILARRMRISIEYPHRGVDCAREVAEVVAPLLGWSAEDVDREVDTYL Mflv_4821|M.gilvum_PYR-GCK HLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSPEDVDREVSTYL MSMEG_1736|M.smegmatis_MC2_155 HLEDILARRMRISIEYPHRGVECAREVAEVVAPILGWSVEDVDREVATYA TH_1838|M.thermoresistible__bu HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWSDADIEREVDTYC MMAR_1225|M.marinum_M HLEDILARRMRVSIEYPHRGVDCAREVADVVAPVLGWTVEDIEREVANYK MUL_2667|M.ulcerans_Agy99 HLEDILARRMRVSIEYPHRGVDCAREVADVVAPVLGWTVEDIEREVANYK Mb3330c|M.bovis_AF2122/97 HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYM Rv3302c|M.tuberculosis_H37Rv HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYM MLBr_00713|M.leprae_Br4923 HLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDREVATYN MAV_4278|M.avium_104 HLEDILARRMRISIEYSHRGVDCAREVADVVAPVLGWTAGDVEREVANYT MAB_3655c|M.abscessus_ATCC_199 HLEDILARRMRIAIEYPHRGVDCAQEVAELVAPVLGWSAEDIVREVDTYR ***********::***.**** **:***::***:***: *: *** .* Mvan_1620|M.vanbaalenii_PYR-1 ARVEAEVLSQTQPDDESADALRAAAPEARAEILEPVPLK--------- Mflv_4821|M.gilvum_PYR-GCK ARVEAEVQSQTQPDDASADALRAAAPEARAEILEPVPLN--------- MSMEG_1736|M.smegmatis_MC2_155 ARVDAEVRSQQQPDDESADALRQAAPEARAEILEPVPLN--------- TH_1838|M.thermoresistible__bu ARVEAEVRSQQQPDDESADALRQAAPEARAMILEPVPLD--------- MMAR_1225|M.marinum_M ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLN--------- MUL_2667|M.ulcerans_Agy99 ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLN--------- Mb3330c|M.bovis_AF2122/97 ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD--------- Rv3302c|M.tuberculosis_H37Rv ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD--------- MLBr_00713|M.leprae_Br4923 ARVEAEVLSQAQPDDVSADMLRASAPEARTKIIEPVSLT--------- MAV_4278|M.avium_104 ARVQAEILSQAQPDDVSADELRASAPEARAEILEPVPLN--------- MAB_3655c|M.abscessus_ATCC_199 ARVDAEVRSQRQPDDASADALRVAAPEARSFIVEPVTETGTVLSPATK ***:**: ** **** *** ** :*****: *:***.