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SNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLAS GTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLY DRLGGAKSVPAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYGAVVRCSTQVV ALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVS DVAMILRTEKSVMFVIPWGSHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVYA GLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDAAVQFIPARVAPSITEKVSLL GADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPGYLKVEAAYAAA AEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYMARVEAEVLSQAQPDD VSADMLRASAPEARAEILEPVPLD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3302c | glpD2 | - | 100% (585) | PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD2 |
M. tuberculosis H37Rv | Rv2249c | glpD1 | 2e-64 | 36.19% (514) | glycerol-3-phosphate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3330c | glpD2 | 0.0 | 100.00% (585) | glycerol-3-phosphate dehydrogenase |
M. gilvum PYR-GCK | Mflv_4821 | - | 0.0 | 85.30% (585) | FAD dependent oxidoreductase |
M. leprae Br4923 | MLBr_00713 | glpD | 0.0 | 90.92% (584) | putative glycerol-3-phosphate dehydrogenase |
M. abscessus ATCC 19977 | MAB_3655c | - | 0.0 | 82.81% (576) | glycerol-3-phosphate dehydrogenase |
M. marinum M | MMAR_1225 | glpD2 | 0.0 | 91.45% (585) | glycerol-3-phosphate dehydrogenase GlpD2 |
M. avium 104 | MAV_4278 | - | 0.0 | 89.40% (585) | glycerol-3-phosphate dehydrogenase 2 |
M. smegmatis MC2 155 | MSMEG_1736 | - | 0.0 | 85.47% (585) | glycerol-3-phosphate dehydrogenase 2 |
M. thermoresistible (build 8) | TH_1838 | glpD2 | 0.0 | 84.38% (589) | PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD2 |
M. ulcerans Agy99 | MUL_2667 | glpD2 | 0.0 | 91.45% (585) | glycerol-3-phosphate dehydrogenase GlpD2 |
M. vanbaalenii PYR-1 | Mvan_1620 | - | 0.0 | 85.37% (588) | FAD dependent oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4821|M.gilvum_PYR-GCK MSDPIPAPGNGETF----LGPDERARAWQRLGSEQFDVIVIGGGIVGAGA Mvan_1620|M.vanbaalenii_PYR-1 MGHVIPAPGNGQTF----LGPDHRVRAWQRLGNEQFDVIVIGGGVVGAGA MSMEG_1736|M.smegmatis_MC2_155 MTVPKPAPGDGQTF----LGPQQRAQAWEQLGNQQFDVVVIGGGVVGAGA TH_1838|M.thermoresistible__bu VSHPILRPGHGPTL----LGPEQRQRAWDRLGSEQFDVVVIGGGVVGSGA Rv3302c|M.tuberculosis_H37Rv MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGC Mb3330c|M.bovis_AF2122/97 MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGC MLBr_00713|M.leprae_Br4923 MTDLIQAPESEQTWPASALGPQQRAAAWERFGTEQFDVVVIGGGVVGSGC MMAR_1225|M.marinum_M MSNPTDASQRDQTGPAGSLGPEQRALAWERLGAEQFDVVVIGGGVVGSGC MUL_2667|M.ulcerans_Agy99 MSNPTDASQRDQTGPADSLGPEQRALAWERLGAEQFDVVVIGGGVVGSGC MAV_4278|M.avium_104 MSDPIHALG-EPGSPASALGPRQRAAAWDRLGAEQFDVVVIGGGVVGSGC MAB_3655c|M.abscessus_ATCC_199 MSDATSPSGSSGPT-YTFLGPEARSLNWERLGSEQFDVIVIGGGVVGAGS : *** * *.::* :****:*****:**:*. Mflv_4821|M.gilvum_PYR-GCK ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Mvan_1620|M.vanbaalenii_PYR-1 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MSMEG_1736|M.smegmatis_MC2_155 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL TH_1838|M.thermoresistible__bu ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Rv3302c|M.tuberculosis_H37Rv ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL Mb3330c|M.bovis_AF2122/97 ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MLBr_00713|M.leprae_Br4923 ALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MMAR_1225|M.marinum_M ALDAATRGLKVALIEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MUL_2667|M.ulcerans_Agy99 ALDAATRGLKVALIEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MAV_4278|M.avium_104 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREAL MAB_3655c|M.abscessus_ATCC_199 ALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVQEAL *************:****:***************************:*** Mflv_4821|M.gilvum_PYR-GCK HERELSLTTLAPHLVKPLPFLFPLTNRVWERPYIAAGIFLYDQLGGAKSV Mvan_1620|M.vanbaalenii_PYR-1 HERELSLTTLAPHLVKPLPFLFPLTNRGWERPYIAAGIFLYDQLGGAKSV MSMEG_1736|M.smegmatis_MC2_155 HERELSLTTLAPHLVKPLPFLFPLTNRWWERPYVAAGIFLYDQLGGAKSV TH_1838|M.thermoresistible__bu HERELSLTTLAPHLVKPLPFLYPLTRRWWERPYVALGIFLYDQLGGARSL Rv3302c|M.tuberculosis_H37Rv YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV Mb3330c|M.bovis_AF2122/97 YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV MLBr_00713|M.leprae_Br4923 YERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSV MMAR_1225|M.marinum_M FERELSLTTLAPHLVKPLPFLFPLTKRGWERPYIAAGIFLYDRLGGAKSV MUL_2667|M.ulcerans_Agy99 FERELSLTTLAPHLVKPLPFLFPLTKRGWERPYIAAGIFLYDRLGGAKSV MAV_4278|M.avium_104 YERELSLTTLAPHLVKPMPFLFPLTNRLWERPYIAAGIFLYDRLGGAKSV MAB_3655c|M.abscessus_ATCC_199 RERELSLSTLAPHLVKPLPFLFPLTSRWWERPYVAAGIFLYDQMGGAKSV ******:*********:***:*** * *****:* ******::***:*: Mflv_4821|M.gilvum_PYR-GCK PPQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY Mvan_1620|M.vanbaalenii_PYR-1 PAQKHLTRSGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY MSMEG_1736|M.smegmatis_MC2_155 PAQKHLTKAGALRLAPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY TH_1838|M.thermoresistible__bu PAQKHLTKAGALRLAPGLRRDSLIGGIRYYDTVVDDARHTLTVARTAAHY Rv3302c|M.tuberculosis_H37Rv PAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY Mb3330c|M.bovis_AF2122/97 PAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHY MLBr_00713|M.leprae_Br4923 PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTLTVARTAAHY MMAR_1225|M.marinum_M PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTASHY MUL_2667|M.ulcerans_Agy99 PAQKHLTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTASHY MAV_4278|M.avium_104 PAQKHLTRAGALRLCPGLKRSALIGGIRYYDTIVDDARHTLTVARTAAHY MAB_3655c|M.abscessus_ATCC_199 PAQKHLTRAGALRLAPGLKRNSLIGGIRYYDTVVDDARHTMTVARTAAHY *.*:*:*::*****.***:*.:**********:*******:******:** Mflv_4821|M.gilvum_PYR-GCK GAVVRTSTQVVALLREGDRVTGVQVRDSEDGRVTDVRGHVVVNATGVWTD Mvan_1620|M.vanbaalenii_PYR-1 SAVVRTSTQVVALLREGDRVTGVRVRDSENGEVTEVRGHVVVNATGVWTD MSMEG_1736|M.smegmatis_MC2_155 GAVVRSSTQVVALLREGDRVTGVRVRDSEDGSVTEVNGHVVVNATGVWTD TH_1838|M.thermoresistible__bu GAVIRSSTQVVALLREGDRVTGVTVRDSETGAVTDVHGHVVVNATGVWTD Rv3302c|M.tuberculosis_H37Rv GAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTD Mb3330c|M.bovis_AF2122/97 GAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTD MLBr_00713|M.leprae_Br4923 GAVVRCSTQVVALLREGDRVIGVRVRDSEDGAVTEIRGHVVVNATGVWTD MMAR_1225|M.marinum_M GAVVRCSTQVVALLREGDRVVGVRVRDSEDGSITEVRGHVVVNATGVWTD MUL_2667|M.ulcerans_Agy99 GAVVRCSTQVVALLREGDRVVGVRVRDSEDGSITEVRGHVVVNATGVWTD MAV_4278|M.avium_104 GVVVRNSTQVVALLREGDRVTGVRVRDSEDGSVTEVRGHVVVNATGVWTD MAB_3655c|M.abscessus_ATCC_199 GAVVRASTQVVSLLREGDRVTGVLVRDTESGAETEVRGHVVINATGVWTD ..*:* *****:******** ** ***:* * :::.****:******** Mflv_4821|M.gilvum_PYR-GCK EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG Mvan_1620|M.vanbaalenii_PYR-1 EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG MSMEG_1736|M.smegmatis_MC2_155 EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG TH_1838|M.thermoresistible__bu EIQALSKQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG Rv3302c|M.tuberculosis_H37Rv EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG Mb3330c|M.bovis_AF2122/97 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWG MLBr_00713|M.leprae_Br4923 EIQALSKQRGRFQVRVSKGVHVVVPRDRIVSDVAMILRTKKSVMFIIPWG MMAR_1225|M.marinum_M EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFIIPWG MUL_2667|M.ulcerans_Agy99 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFIIPWG MAV_4278|M.avium_104 EIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAIILRTEKSVMFVIPWG MAB_3655c|M.abscessus_ATCC_199 EIQALSKTRGRFRVTASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWG ******* ****:* .*****:*********:**:****:***:*:**** Mflv_4821|M.gilvum_PYR-GCK THWIIGTTDTDWNLDLAHPAATKADIDYILGHVNKVLATPLTHDDIDGVY Mvan_1620|M.vanbaalenii_PYR-1 THWIIGTTDTDWHLDLAHPAATKADIDYILGHVNKVLATPLTHDDIDGVY MSMEG_1736|M.smegmatis_MC2_155 THWIIGTTDTDWNLDLAHPAATKADIDYILGHVNTVLATPLTHDDIDGVY TH_1838|M.thermoresistible__bu THWIIGTTDTDWNLDLAHPAATKADIDYILGQVNRALATPLTHADIDGVY Rv3302c|M.tuberculosis_H37Rv SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY Mb3330c|M.bovis_AF2122/97 SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY MLBr_00713|M.leprae_Br4923 NHWIIGTTDTDWNLDLAHPAATKADIDYILQTVNTVLATPLTHADIDGVY MMAR_1225|M.marinum_M SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY MUL_2667|M.ulcerans_Agy99 SHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVY MAV_4278|M.avium_104 SHWIIGTTDTDWDLDLAHPAATKADIDYILSTVNTVLAIPLTHADIDGVY MAB_3655c|M.abscessus_ATCC_199 NHWIIGTTDTEWNLDLAHPAATKVDIDYILDHVNTVLATPLTHNDIDGVY .*********:*.**********.****** ** .** **** ****** Mflv_4821|M.gilvum_PYR-GCK AGLRPLLAGESEETSKLSREHAVAVPSPGLVAIAGGKYTTYRVMAEDAID Mvan_1620|M.vanbaalenii_PYR-1 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAEDAID MSMEG_1736|M.smegmatis_MC2_155 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAADAID TH_1838|M.thermoresistible__bu AGLRPLLAGESEETSKLSREHAVAVPAPGLIAIAGGKYTTYRVMGEDAID Rv3302c|M.tuberculosis_H37Rv AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID Mb3330c|M.bovis_AF2122/97 AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID MLBr_00713|M.leprae_Br4923 AGLRPLLAGESDDTSKLTREHAVAVPVAGLVAIAGGKYTTYRVMAADAID MMAR_1225|M.marinum_M AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID MUL_2667|M.ulcerans_Agy99 AGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAID MAV_4278|M.avium_104 AGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAADAID MAB_3655c|M.abscessus_ATCC_199 AGLRPLLAGENDDTSKLSREHAVAVAAPGLVAIAGGKYTTYRVMASDAVD **********.::****:*******. .**:*************. **:* Mflv_4821|M.gilvum_PYR-GCK AAAEFIPTRVAPSITEKVPLMGADGYFALINQTQSVGTYYDLHPYRVRHL Mvan_1620|M.vanbaalenii_PYR-1 AAAEFIPTRVAPSITERVPLMGADGYFALINQTQSVGAHYGLHPYRVRHL MSMEG_1736|M.smegmatis_MC2_155 AAAEFVPTRVAPSITEKVPLMGADGYFALINQTEHVGRQYGLHPYRVRHL TH_1838|M.thermoresistible__bu AAAEFIPARVAPSITEKVPLLGADGYFALINQTETVGAHYGLHPYRVRHL Rv3302c|M.tuberculosis_H37Rv AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHL Mb3330c|M.bovis_AF2122/97 AAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHL MLBr_00713|M.leprae_Br4923 AAVAFVPARVAPSITEKVGLLGADGYFALINQVEHVAALQGLHPYRVRHL MMAR_1225|M.marinum_M AAVQFVPARVAPSITEKVSLLGADGYFALVNQVEHVGEMVGLHPYRVRHL MUL_2667|M.ulcerans_Agy99 AAVQFVPARVAPSITEKVSLLGADGYFALVNQVEHVGEMVGLHPYRVRHL MAV_4278|M.avium_104 AAAQFIPARVAPSITEKVSLLGADGYFALINQAEHVAQLRGLHPYRVRHL MAB_3655c|M.abscessus_ATCC_199 MASEFVPARVAPSITEKVPLLGADGYFALINQTEHVGETYGLHPYRVRHL * *:*:********:* *:********:**.: *. .********* Mflv_4821|M.gilvum_PYR-GCK LDRYGSLIGEVLKLAED----NPDLLNPITEAPVYLKVEAAYAAAAEGAL Mvan_1620|M.vanbaalenii_PYR-1 LDRYGSLIGEVLKLASDLAAVRPDLLEPITDAPVYLKVEAAYAAAAEGAL MSMEG_1736|M.smegmatis_MC2_155 LDRYGSLIGEVLALADG----KPELLEPITEAPVYLKVEAAYAAAAESAL TH_1838|M.thermoresistible__bu LDRYGSLIGEVLQMAGRDGAGRPDLLEPITDAPVYLKVEAWYAAAAEGAL Rv3302c|M.tuberculosis_H37Rv LDRYGSLISDVLAMAAS----DPSLLSPITEAPGYLKVEAAYAAAAEGAL Mb3330c|M.bovis_AF2122/97 LDRYGSLISDVLAMAAS----DPSLLSPITEAPGYLKVEAAYAAAAEGAL MLBr_00713|M.leprae_Br4923 LDRYGALIGDVLALAAE----APDLLSPIQEAPGYLKVEARYAVTAEGAL MMAR_1225|M.marinum_M LDRYGSLINEVLELAAD----DPDLLTPIKEAPGYLKVEALYAVTAEGAL MUL_2667|M.ulcerans_Agy99 LDRYGSLINEVLELAAD----DPDLLTPIKEAPGYLKVEALYAVTAEGAL MAV_4278|M.avium_104 LDRYGSLIGDVLALAAD----RPDLLNPITEAPGYLRVEALYAVTAEGAL MAB_3655c|M.abscessus_ATCC_199 LDRYGSLIGEVLACAGT----DHSLLQPITKAPMYLKVEARYAVAAEGAL *****:**.:** * .** ** .** **:*** **.:**.** Mflv_4821|M.gilvum_PYR-GCK HLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSPEDVDREVSTYL Mvan_1620|M.vanbaalenii_PYR-1 HLEDILARRMRISIEYPHRGVDCAREVAEVVAPLLGWSAEDVDREVDTYL MSMEG_1736|M.smegmatis_MC2_155 HLEDILARRMRISIEYPHRGVECAREVAEVVAPILGWSVEDVDREVATYA TH_1838|M.thermoresistible__bu HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWSDADIEREVDTYC Rv3302c|M.tuberculosis_H37Rv HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYM Mb3330c|M.bovis_AF2122/97 HLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYM MLBr_00713|M.leprae_Br4923 HLEDILARRMRVSIEYPHRGVACAREVADVVAPVLGWTAEDIDREVATYN MMAR_1225|M.marinum_M HLEDILARRMRVSIEYPHRGVDCAREVADVVAPVLGWTVEDIEREVANYK MUL_2667|M.ulcerans_Agy99 HLEDILARRMRVSIEYPHRGVDCAREVADVVAPVLGWTVEDIEREVANYK MAV_4278|M.avium_104 HLEDILARRMRISIEYSHRGVDCAREVADVVAPVLGWTAGDVEREVANYT MAB_3655c|M.abscessus_ATCC_199 HLEDILARRMRIAIEYPHRGVDCAQEVAELVAPVLGWSAEDIVREVDTYR ***********::***.**** **:***::***:***: *: *** .* Mflv_4821|M.gilvum_PYR-GCK ARVEAEVQSQTQPDDASADALRAAAPEARAEILEPVPLN--------- Mvan_1620|M.vanbaalenii_PYR-1 ARVEAEVLSQTQPDDESADALRAAAPEARAEILEPVPLK--------- MSMEG_1736|M.smegmatis_MC2_155 ARVDAEVRSQQQPDDESADALRQAAPEARAEILEPVPLN--------- TH_1838|M.thermoresistible__bu ARVEAEVRSQQQPDDESADALRQAAPEARAMILEPVPLD--------- Rv3302c|M.tuberculosis_H37Rv ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD--------- Mb3330c|M.bovis_AF2122/97 ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD--------- MLBr_00713|M.leprae_Br4923 ARVEAEVLSQAQPDDVSADMLRASAPEARTKIIEPVSLT--------- MMAR_1225|M.marinum_M ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLN--------- MUL_2667|M.ulcerans_Agy99 ARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLN--------- MAV_4278|M.avium_104 ARVQAEILSQAQPDDVSADELRASAPEARAEILEPVPLN--------- MAB_3655c|M.abscessus_ATCC_199 ARVDAEVRSQRQPDDASADALRVAAPEARSFIVEPVTETGTVLSPATK ***:**: ** **** *** ** :*****: *:***.