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LKPGVPTLDRVVSPTATDSTVHDQAPSVARLFRDRVAATPAAEAFRFPDDGSWRSVTWQQVGDRVRLIAA GLIALGVAPEDRVALASSTRYEWVLADFSVLCAGAATTTLYPTTNARDVAFIVANSGSRIVIAEDQTQVD KLLEHRSELPDLEKIVIIDGDGDGEFVITLDQLEELGAQLLATSPDIVEQRIEGIRPDHLASIIYTSGTT GRPKGVRLPHRAWTYTAAAIDSLGILRADDLNFLWLPLAHAFGKVMLALPLLVGFPTAIDGRVDRIVDNL AAVRPTFMAAAPRIFEKAHARIQAVVADEGGLKKRLFDWAVNVGIEVSRAREGGATPSRLLALQHAIADR LVLSTIRERFGGRLRFFVSAAAPLNRDIARWFDAIGIIVLEGYGLTETAAASFINRPGAYRFGTVGIPFP GTEVKIAADGEILLRSPGVMTAYHDLPEATARALDADGWFYTGDIGEIDDDGFLRITDRKKDLFKTSQGK YVAPSAVAAAFKAVCPYVSEIIVYGEERPYCVALVSLDGEAITDWAAKNGLENLSYAELARHDATRELIA GYVDELNEQLNRWEQVKRFALLDRELSIAAGDLTPSLKAKRNVIVKNFADTIAELYA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1594 | - | - | 100% (617) | AMP-dependent synthetase and ligase |
M. vanbaalenii PYR-1 | Mvan_3549 | - | 4e-95 | 35.44% (570) | AMP-dependent synthetase and ligase |
M. vanbaalenii PYR-1 | Mvan_2578 | - | 2e-33 | 25.74% (540) | thioester reductase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1576 | fadD11 | 5e-88 | 35.58% (607) | fatty-acid-CoA ligase |
M. gilvum PYR-GCK | Mflv_2962 | - | 1e-101 | 37.76% (572) | AMP-dependent synthetase and ligase |
M. tuberculosis H37Rv | Rv2187 | fadD15 | 5e-90 | 33.86% (570) | long-chain-fatty-acid-CoA ligase fadD15 (fatty-acid-CoA |
M. leprae Br4923 | MLBr_00887 | - | 4e-93 | 33.82% (612) | putative long-chain-fatty-acid-CoA ligase |
M. abscessus ATCC 19977 | MAB_1978c | - | 4e-97 | 35.27% (601) | long-chain-fatty-acid--CoA ligase FadD |
M. marinum M | MMAR_2071 | fadD11_1 | 0.0 | 71.81% (596) | long-chain-fatty-acid-CoA ligase, FadD11_1 |
M. avium 104 | MAV_2307 | - | 9e-97 | 36.52% (575) | putative acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4254 | - | 3e-99 | 36.35% (575) | AMP-binding enzyme |
M. thermoresistible (build 8) | TH_4043 | - | 0.0 | 54.63% (615) | PUTATIVE AMP-dependent synthetase and ligase |
M. ulcerans Agy99 | MUL_3274 | fadD11_1 | 0.0 | 71.14% (596) | long-chain-fatty-acid-CoA ligase, FadD11_1 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2071|M.marinum_M ------------------MRP------TLAHERPDIAKI---DNRPPSVA MUL_3274|M.ulcerans_Agy99 ------------------MRP------TLAHERPDIAKI---DNRPPSVA Mvan_1594|M.vanbaalenii_PYR-1 ------------------MKPGVPTLDRVVSPTATDSTV---HDQAPSVA TH_4043|M.thermoresistible__bu ----------------MSIDSNQRSTSSPTTSRADTARAGLAENAPANLA Mflv_2962|M.gilvum_PYR-GCK -----------------------------MTAREFTVPAPFTVEERDNIV MSMEG_4254|M.smegmatis_MC2_155 -------------------------------MREDSIPASFTVGEYDNVA MLBr_00887|M.leprae_Br4923 -------------------------------MREFSVPTRFSVGEHDNIA MAV_2307|M.avium_104 -------------------------------MREYSVPARFSVGENENIA Rv2187|M.tuberculosis_H37Rv -------------------------------MREISVPAPFTVGEHDNVA MAB_1978c|M.abscessus_ATCC_199 -------------------------------MREFSVPAPFTVEDNASVV Mb1576|M.bovis_AF2122/97 MGRHGSRWSRPPCFRVLRLWTYAHRCDLGHTDPLSRRTEMTTTERPTTMC .: MMAR_2071|M.marinum_M RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP MUL_3274|M.ulcerans_Agy99 RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP Mvan_1594|M.vanbaalenii_PYR-1 RLFRDRVAATPAAEAFRFPDDGSWRSVTWQQVGDRVRLIAAGLIALGVAP TH_4043|M.thermoresistible__bu AMFFDRVRRSGDKEAFRKLDGDRWVSLTWNDTAAQVEAVAAGLLALGIAP Mflv_2962|M.gilvum_PYR-GCK GAVFTHERDDPDHVIFQRLVDGKWIDVTARQAAGQIRSAARGLIAEGVQA MSMEG_4254|M.smegmatis_MC2_155 GCVYAHETDDPDHVILRRLVDGTWTDVTCAQAAAQIRSAALGLIAEGVQP MLBr_00887|M.leprae_Br4923 AVVFEHERDDPNLVIYQRQIDGVWTDVTCAEAASQIRSAALGLIALGMQA MAV_2307|M.avium_104 TMVFEHERDDPNFVIYQRQVDGEWTDVTCAEAAAQIRSAALGLISLGVQA Rv2187|M.tuberculosis_H37Rv AMVFEHERDDPDYVIYQRLIDGVWTDVTCAEAANQIRAAALGLISLGVQA MAB_1978c|M.abscessus_ATCC_199 RAVYDYEREDPNQAAFSRLIDDTWTPVTYAEAAAQIRAVANGLIAKGVAP Mb1576|M.bovis_AF2122/97 EAFQRTAVMDPDAVALRTPGGN--QTMTWRDYAAQVRRVAAGLAGLGVRR . .. :* : . :: * ** . *: MMAR_2071|M.marinum_M QDRVALASSTRYEWVLVDFAVMCAGAATTTVYPTTIAADVAYIVANSGSR MUL_3274|M.ulcerans_Agy99 QDRVALASSTRYEWVLVDFAVTCAGAATTTVYPTTIAADVAYIVANSGSR Mvan_1594|M.vanbaalenii_PYR-1 EDRVALASSTRYEWVLADFSVLCAGAATTTLYPTTNARDVAFIVANSGSR TH_4043|M.thermoresistible__bu EDRVAIASSTRYEWVLADLAIMCAGAATTTVYPTSNAADTAYIIGDSGSR Mflv_2962|M.gilvum_PYR-GCK GDRVALLSATRYEWPILDFAILSIGAVTVPIYETSSAEQVQFVLADSGAV MSMEG_4254|M.smegmatis_MC2_155 GDRVAILSATRYEWPIIDFAILSIGAVTVPIYETSAAEQVRFVLENSESV MLBr_00887|M.leprae_Br4923 GDRVSIFSATCFEWAILDLAILSVGAVTVPIYETSSAKQVRWILQDSDAV MAV_2307|M.avium_104 GDRVSIFSATRYEWAILDLAILAVGAVTVPIYETSSAEQVRWVLQDSEAV Rv2187|M.tuberculosis_H37Rv GDRVVIFSATRYEWAILDFAILAVGAVTVPTYETSSAEQVRWVLQDSEAV MAB_1978c|M.abscessus_ATCC_199 GDRVALISATRYEWTIIDYAVLSIGAITVPIYETSSADQVRWVLQDSAAV Mb1576|M.bovis_AF2122/97 GDTVSLMMANRIEFYPLDVGAQHVGATSFSVYNTLPAEQLTYVFDNAGTK * * : :. *: * . ** : . * * * : ::. :: : MMAR_2071|M.marinum_M VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---SWVITLAELEQL MUL_3274|M.ulcerans_Agy99 VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---GWVITLAELEQL Mvan_1594|M.vanbaalenii_PYR-1 IVIAEDQTQVDKLLEHRSELPDLEKIVIIDGDGDG---EFVITLDQLEEL TH_4043|M.thermoresistible__bu VVFAEDATQLAKLTERRSELPNVDKVVLFDAAPDTPGDDWVTTLADLTAL Mflv_2962|M.gilvum_PYR-GCK AAIAETDAHAAHIEAQRDTLPALRRIYVIDGS-----------VPALDEL MSMEG_4254|M.smegmatis_MC2_155 LVFAETDAHADKVEQLRDQLPALRKVFRIDGSG----------TPALDEL MLBr_00887|M.leprae_Br4923 LVFAETDAHATMVNQLAGELPALRQVLQINSAG----------ATALDQL MAV_2307|M.avium_104 LAFAETDEHAAMVTELTAELPALRRVLHIDGSG----------PKALDQL Rv2187|M.tuberculosis_H37Rv VLFAETDSHATMVAELSGSVPALREVLQIAGSG----------PNALDRL MAB_1978c|M.abscessus_ATCC_199 ALFVESDAHAKIAEELAPELPNLRTVFHIASTSA---------PAALDEL Mb1576|M.bovis_AF2122/97 VVICEQQ----YVDRVRASGVPIEHIVCVDGAPPG--------TLSLTDL . * : : . . * * MMAR_2071|M.marinum_M GKQLLADSPAAVDQRVAAIGPDQLASLIYTSGTTGRPKGVRLTHGAWTYT MUL_3274|M.ulcerans_Agy99 GKQLLADSPAAVDQRVAAIGPDQLASLIYTYGTTGRPKGVRLTHGAWTYT Mvan_1594|M.vanbaalenii_PYR-1 GAQLLATSPDIVEQRIEGIRPDHLASIIYTSGTTGRPKGVRLPHRAWTYT TH_4043|M.thermoresistible__bu GEEHLRKHPTSVRDAVAGVRPDQLATLIYTSGTTGKPKGVRLPHRAWVYE Mflv_2962|M.gilvum_PYR-GCK AEAGASVDAAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYE MSMEG_4254|M.smegmatis_MC2_155 AEAGKDVDPAELDKRLANIKSSDPATLIYTSGTTGQPKGCQLTHSNLLHE MLBr_00887|M.leprae_Br4923 AEAGASVDVAQLANRLKTLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYE MAV_2307|M.avium_104 AEAAAGVEPAELTARLDGLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYE Rv2187|M.tuberculosis_H37Rv TEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPKGCQLTQSNLVHE MAB_1978c|M.abscessus_ATCC_199 AEAGAGVDPAELEGRLAAIKATDPATLIYTSGTTGRPKGCQLTHSNLVYE Mb1576|M.bovis_AF2122/97 YAAASG-DFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFE . : . . .::*** ****.*** .:.: . MMAR_2071|M.marinum_M ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV MUL_3274|M.ulcerans_Agy99 ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV Mvan_1594|M.vanbaalenii_PYR-1 AAAIDSLG--ILRADDLNFLWLPLAHAFGKVM-LALPLLVGFPTAIDGRV TH_4043|M.thermoresistible__bu GITVAEFG--TLGEDDLQLLWLPLAHAFGKVL-ISGQLACGFASAIDGRV Mflv_2962|M.gilvum_PYR-GCK IRGAKACFPEHLAKGEKLLVFLPLAHVLARAL-TIGAFSNGVTLGFTSDI MSMEG_4254|M.smegmatis_MC2_155 IRGQKECFPDHLAKGERILVFLPLAHVLARAI-TIGAFANKVTLGFTSDI MLBr_00887|M.leprae_Br4923 VRGAKECLPTLLQPGQRLLVFLPLAHVLARAL-TLSAFTYKMTVGFTSDI MAV_2307|M.avium_104 TRGAKESLPTLLDQGQRLLIFLPLAHVLARSL-TLSAFANKVTVGFTSDI Rv2187|M.tuberculosis_H37Rv IKGARAYHPTLLRKGERLLVFLPLAHVLARAI-SMAAFHSKVTVGFTSDI MAB_1978c|M.abscessus_ATCC_199 TRGARAVFPDYLQKGSRTLIFLPLAHVLARGI-AMACFQSKVSVGFTSDI Mb1576|M.bovis_AF2122/97 GYAIDEVLG--IRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADA : . :** ** : . MMAR_2071|M.marinum_M DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVAEQGG-LKKAVFDWSIG MUL_3274|M.ulcerans_Agy99 DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVAEQGG-LKKAVFDWSIG Mvan_1594|M.vanbaalenii_PYR-1 DRIVDNLAAVRPTFMAAAPRIFEKAHARIQAVVADEGG-LKKRLFDWAVN TH_4043|M.thermoresistible__bu DKIVENMGVVRPTFMGAAPRIFEKAHA---KVVTSQKG-VKKKLFDAAFS Mflv_2962|M.gilvum_PYR-GCK KNLVPMFAVFQPTLVVSVPRVFEKVYNTAELNAETGG---KGKIFTAAAN MSMEG_4254|M.smegmatis_MC2_155 KNLVPMFGVFKPTLVISVPRVFEKVYNTAEQNARNDG---KGKIFEIAAE MLBr_00887|M.leprae_Br4923 KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANEG---KSRIFAMAAQ MAV_2307|M.avium_104 KNLLPMFAVFKPTVVVSVPRVFEKVYNTAEQNAANDG---KGRIFAMAVQ Rv2187|M.tuberculosis_H37Rv KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANAG---KGRIFAIAAQ MAB_1978c|M.abscessus_ATCC_199 KTLVPTFGIFKPTFIVSVPRIFEKVYNTARQNAQNDG---KGKIFDAAAD Mb1576|M.bovis_AF2122/97 RTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTVARETDEMKRQALAWAMS : : .:**. :.**::** . * : : MMAR_2071|M.marinum_M VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA MUL_3274|M.ulcerans_Agy99 VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA Mvan_1594|M.vanbaalenii_PYR-1 VGIEVSRAREGGATPSRLLALQHAIADRLVLSTIRERFG-GRLRFFVSAA TH_4043|M.thermoresistible__bu VGREVDRRRFAGEKVPLPMQLAHGLFDRLVFSKIREVFG-GRIKFMISGA Mflv_2962|M.gilvum_PYR-GCK TAIEYSKALDSGG-PGLVLKLKHALFDKLVYGKLRAALG-GRCHAAISGG MSMEG_4254|M.smegmatis_MC2_155 TAIEFSKAQDKGG-PGLLLRVKHAVFDKLVYGKLRAALG-GECHAAISGG MLBr_00887|M.leprae_Br4923 TAVEWSEASHRGG-PGLLLRARHAVFDRLVYRKLRAALG-GDCHASVSGG MAV_2307|M.avium_104 TAVDWSEAADRGR-RGPLLRAKHALFDRLVYHKLRAALG-GDCHASVSGG Rv2187|M.tuberculosis_H37Rv TAVDWSEACDRGG-PGLLLRAKHAVFDRLVYRKLRAALG-GNCRAAVSGG MAB_1978c|M.abscessus_ATCC_199 TAIEYSEALDKGG-PGIVLRAKRAAFDKLVYGKLRAALG-GECVASISGG Mb1576|M.bovis_AF2122/97 VAGKRANALLAGESMSDQLVAEWAKADESVLSKLRERLGFGELRWALSGA .. . * *. * .:* :* * :*.. MMAR_2071|M.marinum_M AALDRNVAQWFDAIGITVLEGYGLTETAAASFINRPNAYRFGTVGWPFPA MUL_3274|M.ulcerans_Agy99 AALDRNVAQRFDAIGITVLEGYRLTETAAASFINRPNAYRFGTVGWPFPA Mvan_1594|M.vanbaalenii_PYR-1 APLNRDIARWFDAIGIIVLEGYGLTETAAASFINRPGAYRFGTVGIPFPG TH_4043|M.thermoresistible__bu APLNRDIAEWFHAAGLLILEGYGLTETAAGAFINRPDNYRLGTVGQVFDG Mflv_2962|M.gilvum_PYR-GCK APLGARLGHFYRGVGLSIYEGYGLTETSAAITVNRVGDLRVGSVGKLVPG MSMEG_4254|M.smegmatis_MC2_155 APLGERLGHFYRGVGLSIYEGYGLTETSAAITVNRLNDLKVGSVGRLVPG MLBr_00887|M.leprae_Br4923 APLGARLGHFYRGVGLTIHEGYGLTETSAAITLNQAGNVKVGTVGNLLPG MAV_2307|M.avium_104 APLGSRLGHFFRGVGLTIHEGYGLTETSSAITVNQVGNVKIGTVGTLLPG Rv2187|M.tuberculosis_H37Rv APLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTVGKPVPG MAB_1978c|M.abscessus_ATCC_199 APLGARLGHFYRGVGLTIYEGYGLTETTAACAVNVIGGLKIGSVGRPLPG Mb1576|M.bovis_AF2122/97 APIPKETLAFFAGIGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPG *.: : . *: : * : :: : . :.*:** . . MMAR_2071|M.marinum_M TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD MUL_3274|M.ulcerans_Agy99 TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD Mvan_1594|M.vanbaalenii_PYR-1 TEVKIAADGEILLRSPGVMTAYHDLPEATARALDADGWFYTGDIGEIDDD TH_4043|M.thermoresistible__bu AQVRIADSGEVQIKGPNVMEGYHNLPDKTAEAITPDGWLRTGDKGELDAD Mflv_2962|M.gilvum_PYR-GCK NSMRLGEDGELLVRGGVVFNGYWGNEEETRAVFT-DGWFHTGDLGAIDDD MSMEG_4254|M.smegmatis_MC2_155 NSMRIADDGELLVKGGVVFNGYWKNEDETKAVIDADGWFHTGDLGAIDDN MLBr_00887|M.leprae_Br4923 NSMRIADDGELLVRGNVVFSGYWHNEQGTIEAFT-EGWFKTGDLGAIDED MAV_2307|M.avium_104 NSMRIAEDGELLVRGGVVFSGYWRNEQATADAFT-DGWFKTGDLGVLDDD Rv2187|M.tuberculosis_H37Rv NSLRIADDGELLVRGGVVFSGYWRNEQATTEAFT-DGWFKTGDLGAVDED MAB_1978c|M.abscessus_ATCC_199 NAVKIAEDGELLVSGGVVFSGYWNNETATSESIV-DGWFHTGDLGAIDED Mb1576|M.bovis_AF2122/97 LQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDSD ::. .** : . :: .* * : :**: *** :* : MMAR_2071|M.marinum_M GYLRITDRKKDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAKPYC MUL_3274|M.ulcerans_Agy99 GYLRITDRKEDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAEPYC Mvan_1594|M.vanbaalenii_PYR-1 GFLRITDRKKDLFKTSQGKYVAPSAVAAAFKAVCPYVSEIIVYGEERPYC TH_4043|M.thermoresistible__bu GFLTITGRIKDLFKTSGGKYIAPPAIEGRFMALCPYAGHMLVFGEARNFC Mflv_2962|M.gilvum_PYR-GCK GFLTIVGRKKEIIVTAGGKNVAPAQLEDRLR-AHPLISQAMAVGDQQPFI MSMEG_4254|M.smegmatis_MC2_155 GFLTIVGRKKEIIVTAGGKNVAPALLEDRLR-AHPLISQAMAVGDKQPFI MLBr_00887|M.leprae_Br4923 GFLTITGRKKEIIVTAGGKNVAPALLEDQLR-AHPLISQALVVGDAKPFV MAV_2307|M.avium_104 GFLKIVGRKKELIVTAGGKNVAPAVLEDRLR-AHPLISQAMVVGDNKPFI Rv2187|M.tuberculosis_H37Rv GFLTITGRKKEIIVTAGGKNVAPAVLEDQLR-AHPLISQAVVVGDAKPFI MAB_1978c|M.abscessus_ATCC_199 GFVTITGRKKEIIVTAGGKNVAPAVLEDQLR-AHPLISQAMAVGDKQPFI Mb1576|M.bovis_AF2122/97 GYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYN *:: :..* :::: .: ** ::*. : : * . :. *: . : MMAR_2071|M.marinum_M VALVSLDSEAITEWAAGHG-LAGKSFAELTRDTKTRELIAGYIDTLNAEL MUL_3274|M.ulcerans_Agy99 VALVSLDSEAITEWAAGHG-LAGKSFAELTRDPKTRELIAGYIDTLNAEL Mvan_1594|M.vanbaalenii_PYR-1 VALVSLDGEAITDWAAKNG-LENLSYAELARHDATRELIAGYVDELNEQL TH_4043|M.thermoresistible__bu VALITVDPDAIADWAKENG-LGDKSYRELVESEEVKQLIGGYVDQLNSEL Mflv_2962|M.gilvum_PYR-GCK AALITVDTEAFPGWKERHHKASDASVADLADDPDLLAEIELAVKDANQAV MSMEG_4254|M.smegmatis_MC2_155 AALITIDPEAFPAWKERNAKSASATVAELAEDPDLIAEINLAVKEANQAV MLBr_00887|M.leprae_Br4923 GALITIDPEAFNGWKQRNSKAADAAIGDLTTDPDLVAEVDAAVKQANLSV MAV_2307|M.avium_104 GALITIDPEAFGGWKQRNHKGAGASVADLTTDPDLVAEVDAAIKDANQAV Rv2187|M.tuberculosis_H37Rv GALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQANLAV MAB_1978c|M.abscessus_ATCC_199 GALITIDPEAIDGWKQRNGKPADATVADLVEDSDLLAEIGTAVKAANQVV Mb1576|M.bovis_AF2122/97 TALLVFDADSLGPYAAQRG--LDASPAALAADPEVIARIAAGVAEGNAKL **: .* ::: : . . : *. : : * : MMAR_2071|M.marinum_M NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA MUL_3274|M.ulcerans_Agy99 NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA Mvan_1594|M.vanbaalenii_PYR-1 NRWEQVKRFALLDRELSIAAGDLTPSLKAKRNVIVKNFADTIAELYA--- TH_4043|M.thermoresistible__bu NRWETIKKWALLPSDLSIEGGELTPSLKVKRAVVEEKNKELLDSFYS--- Mflv_2962|M.gilvum_PYR-GCK SKAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFAADIEALYAKG- MSMEG_4254|M.smegmatis_MC2_155 SNAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFATDIAALYA--- MLBr_00887|M.leprae_Br4923 SHAESIRKFRILPVDFTEQTGELTPTMKVKRNVVAQKFASDIEAIYEKD- MAV_2307|M.avium_104 SHAESIRKFRILPVDFTEDTGELTPTMKVKRNVVAEKFASDIEAIYAKD- Rv2187|M.tuberculosis_H37Rv SHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAIYNKE- MAB_1978c|M.abscessus_ATCC_199 SHAEAIKKFRILPVDFTEATGEMTPTLKVKRNVVAEKFASDIDAIYAGAP Mb1576|M.bovis_AF2122/97 SRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASEL .. * :::: :* .::* ::* :* : : : :* MMAR_2071|M.marinum_M GQAPKSG--------- MUL_3274|M.ulcerans_Agy99 GQAPKSG--------- Mvan_1594|M.vanbaalenii_PYR-1 ---------------- TH_4043|M.thermoresistible__bu ---------------- Mflv_2962|M.gilvum_PYR-GCK ---------------- MSMEG_4254|M.smegmatis_MC2_155 ---------------- MLBr_00887|M.leprae_Br4923 ---------------- MAV_2307|M.avium_104 ---------------- Rv2187|M.tuberculosis_H37Rv ---------------- MAB_1978c|M.abscessus_ATCC_199 Q--------------- Mb1576|M.bovis_AF2122/97 RPQVYEPAAVPSTQPA