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M. vanbaalenii PYR-1 Mvan_1594 (-)

annotation: AMP-dependent synthetase and ligase
coordinates: 1687561 - 1689414
length: 617

LKPGVPTLDRVVSPTATDSTVHDQAPSVARLFRDRVAATPAAEAFRFPDDGSWRSVTWQQVGDRVRLIAA
GLIALGVAPEDRVALASSTRYEWVLADFSVLCAGAATTTLYPTTNARDVAFIVANSGSRIVIAEDQTQVD
KLLEHRSELPDLEKIVIIDGDGDGEFVITLDQLEELGAQLLATSPDIVEQRIEGIRPDHLASIIYTSGTT
GRPKGVRLPHRAWTYTAAAIDSLGILRADDLNFLWLPLAHAFGKVMLALPLLVGFPTAIDGRVDRIVDNL
AAVRPTFMAAAPRIFEKAHARIQAVVADEGGLKKRLFDWAVNVGIEVSRAREGGATPSRLLALQHAIADR
LVLSTIRERFGGRLRFFVSAAAPLNRDIARWFDAIGIIVLEGYGLTETAAASFINRPGAYRFGTVGIPFP
GTEVKIAADGEILLRSPGVMTAYHDLPEATARALDADGWFYTGDIGEIDDDGFLRITDRKKDLFKTSQGK
YVAPSAVAAAFKAVCPYVSEIIVYGEERPYCVALVSLDGEAITDWAAKNGLENLSYAELARHDATRELIA
GYVDELNEQLNRWEQVKRFALLDRELSIAAGDLTPSLKAKRNVIVKNFADTIAELYA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1594--100% (617)AMP-dependent synthetase and ligase
M. vanbaalenii PYR-1Mvan_3549-4e-9535.44% (570) AMP-dependent synthetase and ligase
M. vanbaalenii PYR-1Mvan_2578-2e-3325.74% (540) thioester reductase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1576fadD115e-8835.58% (607) fatty-acid-CoA ligase
M. gilvum PYR-GCKMflv_2962-1e-10137.76% (572) AMP-dependent synthetase and ligase
M. tuberculosis H37RvRv2187fadD155e-9033.86% (570) long-chain-fatty-acid-CoA ligase fadD15 (fatty-acid-CoA
M. leprae Br4923MLBr_00887-4e-9333.82% (612) putative long-chain-fatty-acid-CoA ligase
M. abscessus ATCC 19977MAB_1978c-4e-9735.27% (601) long-chain-fatty-acid--CoA ligase FadD
M. marinum MMMAR_2071fadD11_10.071.81% (596) long-chain-fatty-acid-CoA ligase, FadD11_1
M. avium 104MAV_2307-9e-9736.52% (575) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_4254-3e-9936.35% (575) AMP-binding enzyme
M. thermoresistible (build 8)TH_4043-0.054.63% (615) PUTATIVE AMP-dependent synthetase and ligase
M. ulcerans Agy99MUL_3274fadD11_10.071.14% (596) long-chain-fatty-acid-CoA ligase, FadD11_1

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2071|M.marinum_M               ------------------MRP------TLAHERPDIAKI---DNRPPSVA
MUL_3274|M.ulcerans_Agy99           ------------------MRP------TLAHERPDIAKI---DNRPPSVA
Mvan_1594|M.vanbaalenii_PYR-1       ------------------MKPGVPTLDRVVSPTATDSTV---HDQAPSVA
TH_4043|M.thermoresistible__bu      ----------------MSIDSNQRSTSSPTTSRADTARAGLAENAPANLA
Mflv_2962|M.gilvum_PYR-GCK          -----------------------------MTAREFTVPAPFTVEERDNIV
MSMEG_4254|M.smegmatis_MC2_155      -------------------------------MREDSIPASFTVGEYDNVA
MLBr_00887|M.leprae_Br4923          -------------------------------MREFSVPTRFSVGEHDNIA
MAV_2307|M.avium_104                -------------------------------MREYSVPARFSVGENENIA
Rv2187|M.tuberculosis_H37Rv         -------------------------------MREISVPAPFTVGEHDNVA
MAB_1978c|M.abscessus_ATCC_199      -------------------------------MREFSVPAPFTVEDNASVV
Mb1576|M.bovis_AF2122/97            MGRHGSRWSRPPCFRVLRLWTYAHRCDLGHTDPLSRRTEMTTTERPTTMC
                                                                                   .: 

MMAR_2071|M.marinum_M               RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP
MUL_3274|M.ulcerans_Agy99           RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP
Mvan_1594|M.vanbaalenii_PYR-1       RLFRDRVAATPAAEAFRFPDDGSWRSVTWQQVGDRVRLIAAGLIALGVAP
TH_4043|M.thermoresistible__bu      AMFFDRVRRSGDKEAFRKLDGDRWVSLTWNDTAAQVEAVAAGLLALGIAP
Mflv_2962|M.gilvum_PYR-GCK          GAVFTHERDDPDHVIFQRLVDGKWIDVTARQAAGQIRSAARGLIAEGVQA
MSMEG_4254|M.smegmatis_MC2_155      GCVYAHETDDPDHVILRRLVDGTWTDVTCAQAAAQIRSAALGLIAEGVQP
MLBr_00887|M.leprae_Br4923          AVVFEHERDDPNLVIYQRQIDGVWTDVTCAEAASQIRSAALGLIALGMQA
MAV_2307|M.avium_104                TMVFEHERDDPNFVIYQRQVDGEWTDVTCAEAAAQIRSAALGLISLGVQA
Rv2187|M.tuberculosis_H37Rv         AMVFEHERDDPDYVIYQRLIDGVWTDVTCAEAANQIRAAALGLISLGVQA
MAB_1978c|M.abscessus_ATCC_199      RAVYDYEREDPNQAAFSRLIDDTWTPVTYAEAAAQIRAVANGLIAKGVAP
Mb1576|M.bovis_AF2122/97            EAFQRTAVMDPDAVALRTPGGN--QTMTWRDYAAQVRRVAAGLAGLGVRR
                                      .                 ..    :*  : . ::   * ** . *:  

MMAR_2071|M.marinum_M               QDRVALASSTRYEWVLVDFAVMCAGAATTTVYPTTIAADVAYIVANSGSR
MUL_3274|M.ulcerans_Agy99           QDRVALASSTRYEWVLVDFAVTCAGAATTTVYPTTIAADVAYIVANSGSR
Mvan_1594|M.vanbaalenii_PYR-1       EDRVALASSTRYEWVLADFSVLCAGAATTTLYPTTNARDVAFIVANSGSR
TH_4043|M.thermoresistible__bu      EDRVAIASSTRYEWVLADLAIMCAGAATTTVYPTSNAADTAYIIGDSGSR
Mflv_2962|M.gilvum_PYR-GCK          GDRVALLSATRYEWPILDFAILSIGAVTVPIYETSSAEQVQFVLADSGAV
MSMEG_4254|M.smegmatis_MC2_155      GDRVAILSATRYEWPIIDFAILSIGAVTVPIYETSAAEQVRFVLENSESV
MLBr_00887|M.leprae_Br4923          GDRVSIFSATCFEWAILDLAILSVGAVTVPIYETSSAKQVRWILQDSDAV
MAV_2307|M.avium_104                GDRVSIFSATRYEWAILDLAILAVGAVTVPIYETSSAEQVRWVLQDSEAV
Rv2187|M.tuberculosis_H37Rv         GDRVVIFSATRYEWAILDFAILAVGAVTVPTYETSSAEQVRWVLQDSEAV
MAB_1978c|M.abscessus_ATCC_199      GDRVALISATRYEWTIIDYAVLSIGAITVPIYETSSADQVRWVLQDSAAV
Mb1576|M.bovis_AF2122/97            GDTVSLMMANRIEFYPLDVGAQHVGATSFSVYNTLPAEQLTYVFDNAGTK
                                     * * :  :.  *:   * .    ** : . * *  * :  ::. :: : 

MMAR_2071|M.marinum_M               VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---SWVITLAELEQL
MUL_3274|M.ulcerans_Agy99           VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---GWVITLAELEQL
Mvan_1594|M.vanbaalenii_PYR-1       IVIAEDQTQVDKLLEHRSELPDLEKIVIIDGDGDG---EFVITLDQLEEL
TH_4043|M.thermoresistible__bu      VVFAEDATQLAKLTERRSELPNVDKVVLFDAAPDTPGDDWVTTLADLTAL
Mflv_2962|M.gilvum_PYR-GCK          AAIAETDAHAAHIEAQRDTLPALRRIYVIDGS-----------VPALDEL
MSMEG_4254|M.smegmatis_MC2_155      LVFAETDAHADKVEQLRDQLPALRKVFRIDGSG----------TPALDEL
MLBr_00887|M.leprae_Br4923          LVFAETDAHATMVNQLAGELPALRQVLQINSAG----------ATALDQL
MAV_2307|M.avium_104                LAFAETDEHAAMVTELTAELPALRRVLHIDGSG----------PKALDQL
Rv2187|M.tuberculosis_H37Rv         VLFAETDSHATMVAELSGSVPALREVLQIAGSG----------PNALDRL
MAB_1978c|M.abscessus_ATCC_199      ALFVESDAHAKIAEELAPELPNLRTVFHIASTSA---------PAALDEL
Mb1576|M.bovis_AF2122/97            VVICEQQ----YVDRVRASGVPIEHIVCVDGAPPG--------TLSLTDL
                                      . *                 :  :  . .               *  *

MMAR_2071|M.marinum_M               GKQLLADSPAAVDQRVAAIGPDQLASLIYTSGTTGRPKGVRLTHGAWTYT
MUL_3274|M.ulcerans_Agy99           GKQLLADSPAAVDQRVAAIGPDQLASLIYTYGTTGRPKGVRLTHGAWTYT
Mvan_1594|M.vanbaalenii_PYR-1       GAQLLATSPDIVEQRIEGIRPDHLASIIYTSGTTGRPKGVRLPHRAWTYT
TH_4043|M.thermoresistible__bu      GEEHLRKHPTSVRDAVAGVRPDQLATLIYTSGTTGKPKGVRLPHRAWVYE
Mflv_2962|M.gilvum_PYR-GCK          AEAGASVDAAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYE
MSMEG_4254|M.smegmatis_MC2_155      AEAGKDVDPAELDKRLANIKSSDPATLIYTSGTTGQPKGCQLTHSNLLHE
MLBr_00887|M.leprae_Br4923          AEAGASVDVAQLANRLKTLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYE
MAV_2307|M.avium_104                AEAAAGVEPAELTARLDGLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYE
Rv2187|M.tuberculosis_H37Rv         TEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPKGCQLTQSNLVHE
MAB_1978c|M.abscessus_ATCC_199      AEAGAGVDPAELEGRLAAIKATDPATLIYTSGTTGRPKGCQLTHSNLVYE
Mb1576|M.bovis_AF2122/97            YAAASG-DFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFE
                                               .      : . . .::*** ****.*** .:.:    . 

MMAR_2071|M.marinum_M               ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV
MUL_3274|M.ulcerans_Agy99           ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV
Mvan_1594|M.vanbaalenii_PYR-1       AAAIDSLG--ILRADDLNFLWLPLAHAFGKVM-LALPLLVGFPTAIDGRV
TH_4043|M.thermoresistible__bu      GITVAEFG--TLGEDDLQLLWLPLAHAFGKVL-ISGQLACGFASAIDGRV
Mflv_2962|M.gilvum_PYR-GCK          IRGAKACFPEHLAKGEKLLVFLPLAHVLARAL-TIGAFSNGVTLGFTSDI
MSMEG_4254|M.smegmatis_MC2_155      IRGQKECFPDHLAKGERILVFLPLAHVLARAI-TIGAFANKVTLGFTSDI
MLBr_00887|M.leprae_Br4923          VRGAKECLPTLLQPGQRLLVFLPLAHVLARAL-TLSAFTYKMTVGFTSDI
MAV_2307|M.avium_104                TRGAKESLPTLLDQGQRLLIFLPLAHVLARSL-TLSAFANKVTVGFTSDI
Rv2187|M.tuberculosis_H37Rv         IKGARAYHPTLLRKGERLLVFLPLAHVLARAI-SMAAFHSKVTVGFTSDI
MAB_1978c|M.abscessus_ATCC_199      TRGARAVFPDYLQKGSRTLIFLPLAHVLARGI-AMACFQSKVSVGFTSDI
Mb1576|M.bovis_AF2122/97            GYAIDEVLG--IRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADA
                                               :   .    :** **   :                 .  

MMAR_2071|M.marinum_M               DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVAEQGG-LKKAVFDWSIG
MUL_3274|M.ulcerans_Agy99           DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVAEQGG-LKKAVFDWSIG
Mvan_1594|M.vanbaalenii_PYR-1       DRIVDNLAAVRPTFMAAAPRIFEKAHARIQAVVADEGG-LKKRLFDWAVN
TH_4043|M.thermoresistible__bu      DKIVENMGVVRPTFMGAAPRIFEKAHA---KVVTSQKG-VKKKLFDAAFS
Mflv_2962|M.gilvum_PYR-GCK          KNLVPMFAVFQPTLVVSVPRVFEKVYNTAELNAETGG---KGKIFTAAAN
MSMEG_4254|M.smegmatis_MC2_155      KNLVPMFGVFKPTLVISVPRVFEKVYNTAEQNARNDG---KGKIFEIAAE
MLBr_00887|M.leprae_Br4923          KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANEG---KSRIFAMAAQ
MAV_2307|M.avium_104                KNLLPMFAVFKPTVVVSVPRVFEKVYNTAEQNAANDG---KGRIFAMAVQ
Rv2187|M.tuberculosis_H37Rv         KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANAG---KGRIFAIAAQ
MAB_1978c|M.abscessus_ATCC_199      KTLVPTFGIFKPTFIVSVPRIFEKVYNTARQNAQNDG---KGKIFDAAAD
Mb1576|M.bovis_AF2122/97            RTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTVARETDEMKRQALAWAMS
                                      :   :  .:**.  :.**::**        .       *   :  :  

MMAR_2071|M.marinum_M               VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA
MUL_3274|M.ulcerans_Agy99           VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA
Mvan_1594|M.vanbaalenii_PYR-1       VGIEVSRAREGGATPSRLLALQHAIADRLVLSTIRERFG-GRLRFFVSAA
TH_4043|M.thermoresistible__bu      VGREVDRRRFAGEKVPLPMQLAHGLFDRLVFSKIREVFG-GRIKFMISGA
Mflv_2962|M.gilvum_PYR-GCK          TAIEYSKALDSGG-PGLVLKLKHALFDKLVYGKLRAALG-GRCHAAISGG
MSMEG_4254|M.smegmatis_MC2_155      TAIEFSKAQDKGG-PGLLLRVKHAVFDKLVYGKLRAALG-GECHAAISGG
MLBr_00887|M.leprae_Br4923          TAVEWSEASHRGG-PGLLLRARHAVFDRLVYRKLRAALG-GDCHASVSGG
MAV_2307|M.avium_104                TAVDWSEAADRGR-RGPLLRAKHALFDRLVYHKLRAALG-GDCHASVSGG
Rv2187|M.tuberculosis_H37Rv         TAVDWSEACDRGG-PGLLLRAKHAVFDRLVYRKLRAALG-GNCRAAVSGG
MAB_1978c|M.abscessus_ATCC_199      TAIEYSEALDKGG-PGIVLRAKRAAFDKLVYGKLRAALG-GECVASISGG
Mb1576|M.bovis_AF2122/97            VAGKRANALLAGESMSDQLVAEWAKADESVLSKLRERLGFGELRWALSGA
                                    .. .       *              *. *  .:*  :* *     :*..

MMAR_2071|M.marinum_M               AALDRNVAQWFDAIGITVLEGYGLTETAAASFINRPNAYRFGTVGWPFPA
MUL_3274|M.ulcerans_Agy99           AALDRNVAQRFDAIGITVLEGYRLTETAAASFINRPNAYRFGTVGWPFPA
Mvan_1594|M.vanbaalenii_PYR-1       APLNRDIARWFDAIGIIVLEGYGLTETAAASFINRPGAYRFGTVGIPFPG
TH_4043|M.thermoresistible__bu      APLNRDIAEWFHAAGLLILEGYGLTETAAGAFINRPDNYRLGTVGQVFDG
Mflv_2962|M.gilvum_PYR-GCK          APLGARLGHFYRGVGLSIYEGYGLTETSAAITVNRVGDLRVGSVGKLVPG
MSMEG_4254|M.smegmatis_MC2_155      APLGERLGHFYRGVGLSIYEGYGLTETSAAITVNRLNDLKVGSVGRLVPG
MLBr_00887|M.leprae_Br4923          APLGARLGHFYRGVGLTIHEGYGLTETSAAITLNQAGNVKVGTVGNLLPG
MAV_2307|M.avium_104                APLGSRLGHFFRGVGLTIHEGYGLTETSSAITVNQVGNVKIGTVGTLLPG
Rv2187|M.tuberculosis_H37Rv         APLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTVGKPVPG
MAB_1978c|M.abscessus_ATCC_199      APLGARLGHFYRGVGLTIYEGYGLTETTAACAVNVIGGLKIGSVGRPLPG
Mb1576|M.bovis_AF2122/97            APIPKETLAFFAGIGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPG
                                    *.:       : . *: : * : ::  :     .     :.*:**  . .

MMAR_2071|M.marinum_M               TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD
MUL_3274|M.ulcerans_Agy99           TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD
Mvan_1594|M.vanbaalenii_PYR-1       TEVKIAADGEILLRSPGVMTAYHDLPEATARALDADGWFYTGDIGEIDDD
TH_4043|M.thermoresistible__bu      AQVRIADSGEVQIKGPNVMEGYHNLPDKTAEAITPDGWLRTGDKGELDAD
Mflv_2962|M.gilvum_PYR-GCK          NSMRLGEDGELLVRGGVVFNGYWGNEEETRAVFT-DGWFHTGDLGAIDDD
MSMEG_4254|M.smegmatis_MC2_155      NSMRIADDGELLVKGGVVFNGYWKNEDETKAVIDADGWFHTGDLGAIDDN
MLBr_00887|M.leprae_Br4923          NSMRIADDGELLVRGNVVFSGYWHNEQGTIEAFT-EGWFKTGDLGAIDED
MAV_2307|M.avium_104                NSMRIAEDGELLVRGGVVFSGYWRNEQATADAFT-DGWFKTGDLGVLDDD
Rv2187|M.tuberculosis_H37Rv         NSLRIADDGELLVRGGVVFSGYWRNEQATTEAFT-DGWFKTGDLGAVDED
MAB_1978c|M.abscessus_ATCC_199      NAVKIAEDGELLVSGGVVFSGYWNNETATSESIV-DGWFHTGDLGAIDED
Mb1576|M.bovis_AF2122/97            LQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDSD
                                       ::. .**  : .  :: .*      *   :  :**: ***   :* :

MMAR_2071|M.marinum_M               GYLRITDRKKDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAKPYC
MUL_3274|M.ulcerans_Agy99           GYLRITDRKEDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAEPYC
Mvan_1594|M.vanbaalenii_PYR-1       GFLRITDRKKDLFKTSQGKYVAPSAVAAAFKAVCPYVSEIIVYGEERPYC
TH_4043|M.thermoresistible__bu      GFLTITGRIKDLFKTSGGKYIAPPAIEGRFMALCPYAGHMLVFGEARNFC
Mflv_2962|M.gilvum_PYR-GCK          GFLTIVGRKKEIIVTAGGKNVAPAQLEDRLR-AHPLISQAMAVGDQQPFI
MSMEG_4254|M.smegmatis_MC2_155      GFLTIVGRKKEIIVTAGGKNVAPALLEDRLR-AHPLISQAMAVGDKQPFI
MLBr_00887|M.leprae_Br4923          GFLTITGRKKEIIVTAGGKNVAPALLEDQLR-AHPLISQALVVGDAKPFV
MAV_2307|M.avium_104                GFLKIVGRKKELIVTAGGKNVAPAVLEDRLR-AHPLISQAMVVGDNKPFI
Rv2187|M.tuberculosis_H37Rv         GFLTITGRKKEIIVTAGGKNVAPAVLEDQLR-AHPLISQAVVVGDAKPFI
MAB_1978c|M.abscessus_ATCC_199      GFVTITGRKKEIIVTAGGKNVAPAVLEDQLR-AHPLISQAMAVGDKQPFI
Mb1576|M.bovis_AF2122/97            GYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYN
                                    *:: :..* :::: .: ** ::*. :   :    *  .  :. *: . : 

MMAR_2071|M.marinum_M               VALVSLDSEAITEWAAGHG-LAGKSFAELTRDTKTRELIAGYIDTLNAEL
MUL_3274|M.ulcerans_Agy99           VALVSLDSEAITEWAAGHG-LAGKSFAELTRDPKTRELIAGYIDTLNAEL
Mvan_1594|M.vanbaalenii_PYR-1       VALVSLDGEAITDWAAKNG-LENLSYAELARHDATRELIAGYVDELNEQL
TH_4043|M.thermoresistible__bu      VALITVDPDAIADWAKENG-LGDKSYRELVESEEVKQLIGGYVDQLNSEL
Mflv_2962|M.gilvum_PYR-GCK          AALITVDTEAFPGWKERHHKASDASVADLADDPDLLAEIELAVKDANQAV
MSMEG_4254|M.smegmatis_MC2_155      AALITIDPEAFPAWKERNAKSASATVAELAEDPDLIAEINLAVKEANQAV
MLBr_00887|M.leprae_Br4923          GALITIDPEAFNGWKQRNSKAADAAIGDLTTDPDLVAEVDAAVKQANLSV
MAV_2307|M.avium_104                GALITIDPEAFGGWKQRNHKGAGASVADLTTDPDLVAEVDAAIKDANQAV
Rv2187|M.tuberculosis_H37Rv         GALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQANLAV
MAB_1978c|M.abscessus_ATCC_199      GALITIDPEAIDGWKQRNGKPADATVADLVEDSDLLAEIGTAVKAANQVV
Mb1576|M.bovis_AF2122/97            TALLVFDADSLGPYAAQRG--LDASPAALAADPEVIARIAAGVAEGNAKL
                                     **: .* :::  :   .    . :   *.        :   :   *  :

MMAR_2071|M.marinum_M               NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA
MUL_3274|M.ulcerans_Agy99           NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA
Mvan_1594|M.vanbaalenii_PYR-1       NRWEQVKRFALLDRELSIAAGDLTPSLKAKRNVIVKNFADTIAELYA---
TH_4043|M.thermoresistible__bu      NRWETIKKWALLPSDLSIEGGELTPSLKVKRAVVEEKNKELLDSFYS---
Mflv_2962|M.gilvum_PYR-GCK          SKAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFAADIEALYAKG-
MSMEG_4254|M.smegmatis_MC2_155      SNAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFATDIAALYA---
MLBr_00887|M.leprae_Br4923          SHAESIRKFRILPVDFTEQTGELTPTMKVKRNVVAQKFASDIEAIYEKD-
MAV_2307|M.avium_104                SHAESIRKFRILPVDFTEDTGELTPTMKVKRNVVAEKFASDIEAIYAKD-
Rv2187|M.tuberculosis_H37Rv         SHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAIYNKE-
MAB_1978c|M.abscessus_ATCC_199      SHAEAIKKFRILPVDFTEATGEMTPTLKVKRNVVAEKFASDIDAIYAGAP
Mb1576|M.bovis_AF2122/97            SRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASEL
                                    .. * :::: :*        .::* ::* :*  :  :    :  :*    

MMAR_2071|M.marinum_M               GQAPKSG---------
MUL_3274|M.ulcerans_Agy99           GQAPKSG---------
Mvan_1594|M.vanbaalenii_PYR-1       ----------------
TH_4043|M.thermoresistible__bu      ----------------
Mflv_2962|M.gilvum_PYR-GCK          ----------------
MSMEG_4254|M.smegmatis_MC2_155      ----------------
MLBr_00887|M.leprae_Br4923          ----------------
MAV_2307|M.avium_104                ----------------
Rv2187|M.tuberculosis_H37Rv         ----------------
MAB_1978c|M.abscessus_ATCC_199      Q---------------
Mb1576|M.bovis_AF2122/97            RPQVYEPAAVPSTQPA