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M. marinum M MMAR_2071 (fadD11_1)

annotation: long-chain-fatty-acid-CoA ligase, FadD11_1
coordinates: 2495093 - 2496958
length: 621

RPTLAHERPDIAKIDNRPPSVARMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGI
APQDRVALASSTRYEWVLVDFAVMCAGAATTTVYPTTIAADVAYIVANSGSRVVVAEDQTQVDKLVEHRA
ELPEVARVVVIDGKGDGSWVITLAELEQLGKQLLADSPAAVDQRVAAIGPDQLASLIYTSGTTGRPKGVR
LTHGAWTYTASAIDALNVLGPADLNFLWLPLAHAFGKVMLSLPLLIGFPTAIDGRVDRIVDNLAELHPTV
MGAAPRIFEKAHARIEQMVAEQGGLKKAVFDWSIGVGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIR
ERFGGRIRFFVSAAAALDRNVAQWFDAIGITVLEGYGLTETAAASFINRPNAYRFGTVGWPFPATEAKIA
TDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDADGYLRITDRKKDMFKTSQGKYVAPAAI
QVRFKGLCPYAGELIVVGEAKPYCVALVSLDSEAITEWAAGHGLAGKSFAELTRDTKTRELIAGYIDTLN
AELNRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPAGQAPKSG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2071fadD11_1-100% (621)long-chain-fatty-acid-CoA ligase, FadD11_1
M. marinum MMMAR_3389-4e-9534.67% (597) fatty-acid-CoA ligase
M. marinum MMMAR_5275fadD15_12e-9435.33% (569) long-chain-fatty-acid-CoA ligase FadD15_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1576fadD119e-8834.84% (597) fatty-acid-CoA ligase
M. gilvum PYR-GCKMflv_2962-7e-9536.51% (567) AMP-dependent synthetase and ligase
M. tuberculosis H37RvRv2187fadD152e-9033.61% (595) long-chain-fatty-acid-CoA ligase fadD15 (fatty-acid-CoA
M. leprae Br4923MLBr_00887-2e-8832.61% (595) putative long-chain-fatty-acid-CoA ligase
M. abscessus ATCC 19977MAB_1865-2e-9536.12% (598) fatty-acid-CoA ligase FadD
M. avium 104MAV_3221-5e-9535.94% (601) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_4254-3e-9434.74% (567) AMP-binding enzyme
M. thermoresistible (build 8)TH_4043-0.056.35% (598) PUTATIVE AMP-dependent synthetase and ligase
M. ulcerans Agy99MUL_3274fadD11_10.098.71% (621) long-chain-fatty-acid-CoA ligase, FadD11_1
M. vanbaalenii PYR-1Mvan_1594-0.071.81% (596) AMP-dependent synthetase and ligase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2071|M.marinum_M               ------------------MRP------TLAHERPDIAKI---DNRPPSVA
MUL_3274|M.ulcerans_Agy99           ------------------MRP------TLAHERPDIAKI---DNRPPSVA
Mvan_1594|M.vanbaalenii_PYR-1       ------------------MKPGVPTLDRVVSPTATDSTV---HDQAPSVA
TH_4043|M.thermoresistible__bu      ----------------MSIDSNQRSTSSPTTSRADTARAGLAENAPANLA
Mflv_2962|M.gilvum_PYR-GCK          -----------------------------MTAREFTVPAPFTVEERDNIV
MSMEG_4254|M.smegmatis_MC2_155      -------------------------------MREDSIPASFTVGEYDNVA
Rv2187|M.tuberculosis_H37Rv         -------------------------------MREISVPAPFTVGEHDNVA
MLBr_00887|M.leprae_Br4923          -------------------------------MREFSVPTRFSVGEHDNIA
Mb1576|M.bovis_AF2122/97            MGRHGSRWSRPPCFRVLRLWTYAHRCDLGHTDPLSRRTEMTTTERPTTMC
MAV_3221|M.avium_104                ----------------------------------------MTAERPATLC
MAB_1865|M.abscessus_ATCC_1997      ------------------------------------------MTGPATLC
                                                                                   .: 

MMAR_2071|M.marinum_M               RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP
MUL_3274|M.ulcerans_Agy99           RMFLDRVAASPSAEAFRYPHGDDWESVTWEQVGERVGRLAAGLISLGIAP
Mvan_1594|M.vanbaalenii_PYR-1       RLFRDRVAATPAAEAFRFPDDGSWRSVTWQQVGDRVRLIAAGLIALGVAP
TH_4043|M.thermoresistible__bu      AMFFDRVRRSGDKEAFRKLDGDRWVSLTWNDTAAQVEAVAAGLLALGIAP
Mflv_2962|M.gilvum_PYR-GCK          GAVFTHERDDPDHVIFQRLVDGKWIDVTARQAAGQIRSAARGLIAEGVQA
MSMEG_4254|M.smegmatis_MC2_155      GCVYAHETDDPDHVILRRLVDGTWTDVTCAQAAAQIRSAALGLIAEGVQP
Rv2187|M.tuberculosis_H37Rv         AMVFEHERDDPDYVIYQRLIDGVWTDVTCAEAANQIRAAALGLISLGVQA
MLBr_00887|M.leprae_Br4923          AVVFEHERDDPNLVIYQRQIDGVWTDVTCAEAASQIRSAALGLIALGMQA
Mb1576|M.bovis_AF2122/97            EAFQRTAVMDPDAVALRTPGGN--QTMTWRDYAAQVRRVAAGLAGLGVRR
MAV_3221|M.avium_104                EAFQRNAAIDPDAVVLRTPGAT--QTLTWRELAEQVRKVAAGLAGLGVRR
MAB_1865|M.abscessus_ATCC_1997      AAFQRTAAQHPDRVALRTVGGG--VVITWRQYRERVREIASGLAGLGVGP
                                      .             :         :*  :   ::   * ** . *:  

MMAR_2071|M.marinum_M               QDRVALASSTRYEWVLVDFAVMCAGAATTTVYPTTIAADVAYIVANSGSR
MUL_3274|M.ulcerans_Agy99           QDRVALASSTRYEWVLVDFAVTCAGAATTTVYPTTIAADVAYIVANSGSR
Mvan_1594|M.vanbaalenii_PYR-1       EDRVALASSTRYEWVLADFSVLCAGAATTTLYPTTNARDVAFIVANSGSR
TH_4043|M.thermoresistible__bu      EDRVAIASSTRYEWVLADLAIMCAGAATTTVYPTSNAADTAYIIGDSGSR
Mflv_2962|M.gilvum_PYR-GCK          GDRVALLSATRYEWPILDFAILSIGAVTVPIYETSSAEQVQFVLADSGAV
MSMEG_4254|M.smegmatis_MC2_155      GDRVAILSATRYEWPIIDFAILSIGAVTVPIYETSAAEQVRFVLENSESV
Rv2187|M.tuberculosis_H37Rv         GDRVVIFSATRYEWAILDFAILAVGAVTVPTYETSSAEQVRWVLQDSEAV
MLBr_00887|M.leprae_Br4923          GDRVSIFSATCFEWAILDLAILSVGAVTVPIYETSSAKQVRWILQDSDAV
Mb1576|M.bovis_AF2122/97            GDTVSLMMANRIEFYPLDVGAQHVGATSFSVYNTLPAEQLTYVFDNAGTK
MAV_3221|M.avium_104                GDTVSLMMANRIEFYPLEIGAQHLGATSFSVYNTLPAEQLTYLFDNAGTK
MAB_1865|M.abscessus_ATCC_1997      GDTVALMLTNRPEFHLCDTAVLHCGATPFSVYNTNPPELLGYQFDNADNR
                                     * * :  :.  *:   : .    **.. . * *  .    : . ::   

MMAR_2071|M.marinum_M               VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---SWVITLAELEQL
MUL_3274|M.ulcerans_Agy99           VVVAEDQTQVDKLVEHRAELPEVARVVVIDGKGDG---GWVITLAELEQL
Mvan_1594|M.vanbaalenii_PYR-1       IVIAEDQTQVDKLLEHRSELPDLEKIVIIDGDGDG---EFVITLDQLEEL
TH_4043|M.thermoresistible__bu      VVFAEDATQLAKLTERRSELPNVDKVVLFDAAPDTPGDDWVTTLADLTAL
Mflv_2962|M.gilvum_PYR-GCK          AAIAETDAHAAHIEAQRDTLPALRRIYVIDGS-VP----------ALDEL
MSMEG_4254|M.smegmatis_MC2_155      LVFAETDAHADKVEQLRDQLPALRKVFRIDGSGTP----------ALDEL
Rv2187|M.tuberculosis_H37Rv         VLFAETDSHATMVAELSGSVPALREVLQIAGSGPN----------ALDRL
MLBr_00887|M.leprae_Br4923          LVFAETDAHATMVNQLAGELPALRQVLQINSAGAT----------ALDQL
Mb1576|M.bovis_AF2122/97            VVICEQQYVDRVRAS----GVPIEHIVCVDGAPPG---------TLSLTD
MAV_3221|M.avium_104                VAICEQQYVDRIRAS----GAPVEHIVCIDGAPPG---------TISVEQ
MAB_1865|M.abscessus_ATCC_1997      VVICEQQFLPQVRSAV-GLGGKVEHIICVDGAPEG---------TLDLRS
                                      ..*                 : .:  . .                   

MMAR_2071|M.marinum_M               GKQLLADSPAAVDQRVAAIGPDQLASLIYTSGTTGRPKGVRLTHGAWTYT
MUL_3274|M.ulcerans_Agy99           GKQLLADSPAAVDQRVAAIGPDQLASLIYTYGTTGRPKGVRLTHGAWTYT
Mvan_1594|M.vanbaalenii_PYR-1       GAQLLATSPDIVEQRIEGIRPDHLASIIYTSGTTGRPKGVRLPHRAWTYT
TH_4043|M.thermoresistible__bu      GEEHLRKHPTSVRDAVAGVRPDQLATLIYTSGTTGKPKGVRLPHRAWVYE
Mflv_2962|M.gilvum_PYR-GCK          AEAGASVDAAAVDERVASIRSTDAATLIYTSGTTGRPKGCQLTHSNLLYE
MSMEG_4254|M.smegmatis_MC2_155      AEAGKDVDPAELDKRLANIKSSDPATLIYTSGTTGQPKGCQLTHSNLLHE
Rv2187|M.tuberculosis_H37Rv         TEAGASVDPAELTARLAALRSTDPATLIYTSGTTGRPKGCQLTQSNLVHE
MLBr_00887|M.leprae_Br4923          AEAGASVDVAQLANRLKTLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYE
Mb1576|M.bovis_AF2122/97            LYAAASGDFFDFESTWRAVQPEDIVTLIYTSGTTGNPKGVEMTHANLLFE
MAV_3221|M.avium_104                LYAAAPRD-FDFESTWRSVRPDDVVTLIYTSGTTGNPKGVEMTHANLLFE
MAB_1865|M.abscessus_ATCC_1997      LPPAAD---FDFESAWRSVRPDDVLTIVYTSGTTGPPKGVELTHTNFIEN
                                               .      : . .  :::** **** *** .:.:      

MMAR_2071|M.marinum_M               ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV
MUL_3274|M.ulcerans_Agy99           ASAIDALN--VLGPADLNFLWLPLAHAFGKVM-LSLPLLIGFPTAIDGRV
Mvan_1594|M.vanbaalenii_PYR-1       AAAIDSLG--ILRADDLNFLWLPLAHAFGKVM-LALPLLVGFPTAIDGRV
TH_4043|M.thermoresistible__bu      GITVAEFG--TLGEDDLQLLWLPLAHAFGKVL-ISGQLACGFASAIDGRV
Mflv_2962|M.gilvum_PYR-GCK          IRGAKACFPEHLAKGEKLLVFLPLAHVLARAL-TIGAFSNGVTLGFTSDI
MSMEG_4254|M.smegmatis_MC2_155      IRGQKECFPDHLAKGERILVFLPLAHVLARAI-TIGAFANKVTLGFTSDI
Rv2187|M.tuberculosis_H37Rv         IKGARAYHPTLLRKGERLLVFLPLAHVLARAI-SMAAFHSKVTVGFTSDI
MLBr_00887|M.leprae_Br4923          VRGAKECLPTLLQPGQRLLVFLPLAHVLARAL-TLSAFTYKMTVGFTSDI
Mb1576|M.bovis_AF2122/97            GYAIDEVLG--IRFGDRVTSFLPSAHIADRMTGLYLQEMFGTQVTAVADA
MAV_3221|M.avium_104                CHALNAVLP--SKFGDRVTSYLPSAHIADRAMGLYGLEVFGAQVTVVDDP
MAB_1865|M.abscessus_ATCC_1997      ARITEEMGP--LGFDDRAVSYLPDAHAANRWLTHYQNLLYGLQITTVADP
                                                   :    :** **   :                    

MMAR_2071|M.marinum_M               DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVA-EQGGLKKAVFDWSIG
MUL_3274|M.ulcerans_Agy99           DRIVDNLAELHPTVMGAAPRIFEKAHARIEQMVA-EQGGLKKAVFDWSIG
Mvan_1594|M.vanbaalenii_PYR-1       DRIVDNLAAVRPTFMAAAPRIFEKAHARIQAVVA-DEGGLKKRLFDWAVN
TH_4043|M.thermoresistible__bu      DKIVENMGVVRPTFMGAAPRIFEKAHA---KVVT-SQKGVKKKLFDAAFS
Mflv_2962|M.gilvum_PYR-GCK          KNLVPMFAVFQPTLVVSVPRVFEKVYNTAELNAE-TGG--KGKIFTAAAN
MSMEG_4254|M.smegmatis_MC2_155      KNLVPMFGVFKPTLVISVPRVFEKVYNTAEQNAR-NDG--KGKIFEIAAE
Rv2187|M.tuberculosis_H37Rv         KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAA-NAG--KGRIFAIAAQ
MLBr_00887|M.leprae_Br4923          KNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAA-NEG--KSRIFAMAAQ
Mb1576|M.bovis_AF2122/97            RTIAAALPDVRPTVWGAVPRVWEKLKAGIEFTVARETDEMKRQALAWAMS
MAV_3221|M.avium_104                RAIAAALPDVRPTVWAAVPRIWEKLKAGIEFTVANEQDEATRAALQWAMS
MAB_1865|M.abscessus_ATCC_1997      KAVLSALTDVRPTLFLGVPRVWVKAKMGLDAALQ-EAGPLRRTLAHWAIG
                                      :   :  .:**.  ..**:: *                       :  

MMAR_2071|M.marinum_M               VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA
MUL_3274|M.ulcerans_Agy99           VGLKVSASRQAGRQPALLSRLAYQLADRLVFSTIRERFG-GRIRFFVSAA
Mvan_1594|M.vanbaalenii_PYR-1       VGIEVSRAREGGATPSRLLALQHAIADRLVLSTIRERFG-GRLRFFVSAA
TH_4043|M.thermoresistible__bu      VGREVDRRRFAGEKVPLPMQLAHGLFDRLVFSKIREVFG-GRIKFMISGA
Mflv_2962|M.gilvum_PYR-GCK          TAIEYSKALDSGG-PGLVLKLKHALFDKLVYGKLRAALG-GRCHAAISGG
MSMEG_4254|M.smegmatis_MC2_155      TAIEFSKAQDKGG-PGLLLRVKHAVFDKLVYGKLRAALG-GECHAAISGG
Rv2187|M.tuberculosis_H37Rv         TAVDWSEACDRGG-PGLLLRAKHAVFDRLVYRKLRAALG-GNCRAAVSGG
MLBr_00887|M.leprae_Br4923          TAVEWSEASHRGG-PGLLLRARHAVFDRLVYRKLRAALG-GDCHASVSGG
Mb1576|M.bovis_AF2122/97            VAGKRANALLAGESMSDQLVAEWAKADESVLSKLRERLGFGELRWALSGA
MAV_3221|M.avium_104                VAAQRAAALVAGEQIPDELATEWARADKLVLSKLRERLGFGELRWAVSGA
MAB_1865|M.abscessus_ATCC_1997      VGRRKARASSAGARLSALDNMTHALADRLVLSSIRARMGLDRVKVGASGA
                                    ..         *              *. *  .:*  :* .  :   *..

MMAR_2071|M.marinum_M               AALDRNVAQWFDAIGITVLEGYGLTETAAASFINRPNAYRFGTVGWPFPA
MUL_3274|M.ulcerans_Agy99           AALDRNVAQRFDAIGITVLEGYRLTETAAASFINRPNAYRFGTVGWPFPA
Mvan_1594|M.vanbaalenii_PYR-1       APLNRDIARWFDAIGIIVLEGYGLTETAAASFINRPGAYRFGTVGIPFPG
TH_4043|M.thermoresistible__bu      APLNRDIAEWFHAAGLLILEGYGLTETAAGAFINRPDNYRLGTVGQVFDG
Mflv_2962|M.gilvum_PYR-GCK          APLGARLGHFYRGVGLSIYEGYGLTETSAAITVNRVGDLRVGSVGKLVPG
MSMEG_4254|M.smegmatis_MC2_155      APLGERLGHFYRGVGLSIYEGYGLTETSAAITVNRLNDLKVGSVGRLVPG
Rv2187|M.tuberculosis_H37Rv         APLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTVGKPVPG
MLBr_00887|M.leprae_Br4923          APLGARLGHFYRGVGLTIHEGYGLTETSAAITLNQAGNVKVGTVGNLLPG
Mb1576|M.bovis_AF2122/97            APIPKETLAFFAGIGIPIAEIWGMSELSCVATASHPRDGRLGTVGKLLPG
MAV_3221|M.avium_104                APIPKETLAFFAGIGIPIAEVWGMSELSCVAAVSHPRDARLGSVGKLLPG
MAB_1865|M.abscessus_ATCC_1997      APIPVEVHEFLLALGIPICEGYGMTECTCAGTINRASRIKIGSVGIPAPG
                                    *.:         . *: : * : ::  :     .:    :.*:**    .

MMAR_2071|M.marinum_M               TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD
MUL_3274|M.ulcerans_Agy99           TEAKIATDGEILLRGPGLMTSYHDLPEATEEALDHDGWFHTGDIGEIDAD
Mvan_1594|M.vanbaalenii_PYR-1       TEVKIAADGEILLRSPGVMTAYHDLPEATARALDADGWFYTGDIGEIDDD
TH_4043|M.thermoresistible__bu      AQVRIADSGEVQIKGPNVMEGYHNLPDKTAEAITPDGWLRTGDKGELDAD
Mflv_2962|M.gilvum_PYR-GCK          NSMRLGEDGELLVRGGVVFNGYWGNEEETRAVFT-DGWFHTGDLGAIDDD
MSMEG_4254|M.smegmatis_MC2_155      NSMRIADDGELLVKGGVVFNGYWKNEDETKAVIDADGWFHTGDLGAIDDN
Rv2187|M.tuberculosis_H37Rv         NSLRIADDGELLVRGGVVFSGYWRNEQATTEAFT-DGWFKTGDLGAVDED
MLBr_00887|M.leprae_Br4923          NSMRIADDGELLVRGNVVFSGYWHNEQGTIEAFT-EGWFKTGDLGAIDED
Mb1576|M.bovis_AF2122/97            LQGKIAEDGEYLVRGPLVMKGYRKEPAKTAEAIDSDGWLHTGDVFDIDSD
MAV_3221|M.avium_104                LEGKIADDGEFLVRGPLVMKGYRKEPAKTAEAIDADGWLHTGDILEADAQ
MAB_1865|M.abscessus_ATCC_1997      VEVSLGPDGEVLLRGKNIMRGYRKMPEKTAETVDPEGWLHTGDIGEIDAE
                                     .  :. .**  ::.  :: .*      *  ..  :**: ***    * :

MMAR_2071|M.marinum_M               GYLRITDRKKDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAKPYC
MUL_3274|M.ulcerans_Agy99           GYLRITDRKEDMFKTSQGKYVAPAAIQVRFKGLCPYAGELIVVGEAEPYC
Mvan_1594|M.vanbaalenii_PYR-1       GFLRITDRKKDLFKTSQGKYVAPSAVAAAFKAVCPYVSEIIVYGEERPYC
TH_4043|M.thermoresistible__bu      GFLTITGRIKDLFKTSGGKYIAPPAIEGRFMALCPYAGHMLVFGEARNFC
Mflv_2962|M.gilvum_PYR-GCK          GFLTIVGRKKEIIVTAGGKNVAPAQLEDRLR-AHPLISQAMAVGDQQPFI
MSMEG_4254|M.smegmatis_MC2_155      GFLTIVGRKKEIIVTAGGKNVAPALLEDRLR-AHPLISQAMAVGDKQPFI
Rv2187|M.tuberculosis_H37Rv         GFLTITGRKKEIIVTAGGKNVAPAVLEDQLR-AHPLISQAVVVGDAKPFI
MLBr_00887|M.leprae_Br4923          GFLTITGRKKEIIVTAGGKNVAPALLEDQLR-AHPLISQALVVGDAKPFV
Mb1576|M.bovis_AF2122/97            GYLRVVDRKKELIINAAGKNMSPANIENTILAACPMVGVMMAIGDGRTYN
MAV_3221|M.avium_104                GYLRVVDRKKELIINAAGKNMSPANIENAILAACPMIGVMITIGDGRPYN
MAB_1865|M.abscessus_ATCC_1997      GYLKIVDRKKEIIINEAGKNMSPTNIENAITANTPLAGPVAVIGDRRPYN
                                    *:* :..* :::: .  ** ::*. :   :    *  .   . *: . : 

MMAR_2071|M.marinum_M               VALVSLDSEAITEWAAGHG-LAGKSFAELTRDTKTRELIAGYIDTLNAEL
MUL_3274|M.ulcerans_Agy99           VALVSLDSEAITEWAAGHG-LAGKSFAELTRDPKTRELIAGYIDTLNAEL
Mvan_1594|M.vanbaalenii_PYR-1       VALVSLDGEAITDWAAKNG-LENLSYAELARHDATRELIAGYVDELNEQL
TH_4043|M.thermoresistible__bu      VALITVDPDAIADWAKENG-LGDKSYRELVESEEVKQLIGGYVDQLNSEL
Mflv_2962|M.gilvum_PYR-GCK          AALITVDTEAFPGWKERHHKASDASVADLADDPDLLAEIELAVKDANQAV
MSMEG_4254|M.smegmatis_MC2_155      AALITIDPEAFPAWKERNAKSASATVAELAEDPDLIAEINLAVKEANQAV
Rv2187|M.tuberculosis_H37Rv         GALITIDPEAFEGWKQRNSKTAGASVGDLATDPDLIAEIDAAVKQANLAV
MLBr_00887|M.leprae_Br4923          GALITIDPEAFNGWKQRNSKAADAAIGDLTTDPDLVAEVDAAVKQANLSV
Mb1576|M.bovis_AF2122/97            TALLVFDADSLGPYAAQRG-L-DASPAALAADPEVIARIAAGVAEGNAKL
MAV_3221|M.avium_104                TALLVFDADSVGPYAARHG-LSDASPAALAADPDVIAQIAAGVAAGNAKL
MAB_1865|M.abscessus_ATCC_1997      TALITLDPEALARFAERHG-L-TGRQSELAESPVVRAAIDECVQNANRSL
                                     **: .* ::.  :   .          *.        :   :   *  :

MMAR_2071|M.marinum_M               NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA
MUL_3274|M.ulcerans_Agy99           NRWEQIKKFAVLDRELSIESGDLTPSMKLRRKVVLDKSADEISALYQQPA
Mvan_1594|M.vanbaalenii_PYR-1       NRWEQVKRFALLDRELSIAAGDLTPSLKAKRNVIVKNFADTIAELYA---
TH_4043|M.thermoresistible__bu      NRWETIKKWALLPSDLSIEGGELTPSLKVKRAVVEEKNKELLDSFYS---
Mflv_2962|M.gilvum_PYR-GCK          SKAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFAADIEALYAKG-
MSMEG_4254|M.smegmatis_MC2_155      SNAEAIRKFRILPVDFTEDTGELTPTLKVKRKVVAEKFATDIAALYA---
Rv2187|M.tuberculosis_H37Rv         SHAESIRKFRILPVDFTEDTGELTPTMKVKRKVVAEKFASDIEAIYNKE-
MLBr_00887|M.leprae_Br4923          SHAESIRKFRILPVDFTEQTGELTPTMKVKRNVVAQKFASDIEAIYEKD-
Mb1576|M.bovis_AF2122/97            SRVEQIKRFRILPTLWEPGGDEITLTMKLKRRRIAAKYSAEIEELYASEL
MAV_3221|M.avium_104                SRVEQIKRFRILPTLWEPGGDEITLTMKLKRKPIMAKYAEEIEQLYADPP
MAB_1865|M.abscessus_ATCC_1997      SRVEQIKTFTVLPDVWEPGSEYLTPTTKLRRKPIEEHYCEVIDAMY----
                                    .. * :: : :*          :* : * :*  :  :    :  :*    

MMAR_2071|M.marinum_M               GQAPKSG---------
MUL_3274|M.ulcerans_Agy99           GQAPKSG---------
Mvan_1594|M.vanbaalenii_PYR-1       ----------------
TH_4043|M.thermoresistible__bu      ----------------
Mflv_2962|M.gilvum_PYR-GCK          ----------------
MSMEG_4254|M.smegmatis_MC2_155      ----------------
Rv2187|M.tuberculosis_H37Rv         ----------------
MLBr_00887|M.leprae_Br4923          ----------------
Mb1576|M.bovis_AF2122/97            RPQVYEPAAVPSTQPA
MAV_3221|M.avium_104                PPEVHEPAAA-AVQPV
MAB_1865|M.abscessus_ATCC_1997      ----------------