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VRAVIYTRISDDQAGRGLGVARQLEDCQALADKLGWQVVNHFDDNDISAYSGKRRPGFEAMLEAMKAGQF DALLCFHTDRLYRNMSDLERVIELADARRVEIRTVQGGTLDLSTSAGRMVARILGSVARQESEHSSERRK RANVQRAANGDWVAARRPFGYTMDGEPLEPEATAIRSAITDVLSGKSVRAVARDWNDAGLATTGKADKWT ATSVRRVLLRPRYAALVVHQGKVVGPGSWTPLIDTDTHHGIVAYLNDPARKGKVGFERKYQGSGVYRCGV CGTPVITHMSSGGSPNRVARRAYACPNGFHVRRQGDGLDTYVDTIVIGRLSQPDAAELLSTLSNSEGVDI GALHAQRTALQARQEELASLFADGAISAPQLKLGSAKLTNALETLERDLAAATQGNPASALLQDVNGVAQ LEGRWAELSPDLRGKVIDQLMTVTINRSPKGLRRFDPDYVTVDWKQG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1448 | - | - | 100% (467) | recombinase |
| M. vanbaalenii PYR-1 | Mvan_3261 | - | 2e-06 | 34.04% (94) | resolvase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1612c | - | 2e-64 | 35.55% (481) | phiRv1 integrase |
| M. gilvum PYR-GCK | Mflv_1983 | - | 2e-13 | 29.19% (209) | resolvase domain-containing protein |
| M. tuberculosis H37Rv | Rv1586c | - | 2e-64 | 35.55% (481) | phiRv1 integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1820c | - | 3e-08 | 32.67% (101) | putative resolvase |
| M. marinum M | MMAR_2129 | - | 1e-55 | 32.84% (472) | site-specific integrase |
| M. avium 104 | MAV_3790 | - | 8e-61 | 34.60% (474) | integrase/recombinase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3834 | - | 3e-33 | 27.77% (461) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2129|M.marinum_M MPARKSAGQRVGVGSAAIYARISSDVEGTGLGVARQ-LEDCRKLAEDRGW
MAV_3790|M.avium_104 MGKAKTPAQRVGARSAAIYARISADVEGTGLGVARQ-LEDCRKLAAERGW
Mb1612c|M.bovis_AF2122/97 -------MRYTTPVRAAVYLRISEDRSGEQLGVARQ-REDCLKLCGQRKW
Rv1586c|M.tuberculosis_H37Rv -------MRYTTPVRAAVYLRISEDRSGEQLGVARQ-REDCLKLCGQRKW
TH_3834|M.thermoresistible__bu --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 -------------MRAVIYTRISDDQAGRGLGVARQ-LEDCQALADKLGW
Mflv_1983|M.gilvum_PYR-GCK --------------------MSTEDQADKRNGLEAQ-RAAIDAEAEWRGW
MAB_1820c|M.abscessus_ATCC_199 -------------MDTSTTADTGVLLGYARVSTAHQSLDQQLDALTEAGV
MMAR_2129|M.marinum_M PVGAEYVDNDVSAFSGKPRREYARMLADLASGDRDAVIVYNLDRLHRRPV
MAV_3790|M.avium_104 PIGDEYVDNDVSAYSGKPRREYARMLDDLKSGARDAVIVYNLDRLHRRPV
Mb1612c|M.bovis_AF2122/97 VP-VEYLDNDVSASTGKRRPAYEQMLADITAGKIAAVVAWDLDRLHRRPI
Rv1586c|M.tuberculosis_H37Rv VP-VEYLDNDVSASTGKRRPAYEQMLADITAGKIAAVVAWDLDRLHRRPI
TH_3834|M.thermoresistible__bu ------------------------MLADIRDGLVRAVVVWDLDRLHRRPL
Mvan_1448|M.vanbaalenii_PYR-1 QVVNHFDDNDISAYSGKRRPGFEAMLEAMKAGQFDALLCFHTDRLYRNMS
Mflv_1983|M.gilvum_PYR-GCK DVEHFADEGGSGKHIN---PKLAEVLELLAMGQGEGLIVAKLDRLSRSII
MAB_1820c|M.abscessus_ATCC_199 GPDRIYKDKLSGTSTREQRPGLAALLDYARPG--DGIVVVGIDRLGRNAA
:* * .:: *** *
MMAR_2129|M.marinum_M ELEEFVTLCESVGVRDVATVTADIDLGNDDGLFMARIFAAFAAKESGRKS
MAV_3790|M.avium_104 ELEDFVTLCESVGVRDVATVTADIDLGNDDGLFMARIFAAFAAKESGRKS
Mb1612c|M.bovis_AF2122/97 ELEAFMSLADEK-RLALATVAGDVDLATPQGRLVARLKGSVAAHETEHKK
Rv1586c|M.tuberculosis_H37Rv ELEAFMSLADEK-RLALATVAGDVDLATPQGRLVARLKGSVAAHETEHKK
TH_3834|M.thermoresistible__bu ELEGFMALADER-GLKLATVSGDVDLSTAQGRLIARLKGSVAAHEIEHKR
Mvan_1448|M.vanbaalenii_PYR-1 DLERVIELADARRVEIRTVQGGTLDLSTSAGRMVARILGSVARQESEHSS
Mflv_1983|M.gilvum_PYR-GCK HAATIIECAQKQ-GWSLVLLDLGVDLTTAAGRMFAMNLVNYAQYERELIS
MAB_1820c|M.abscessus_ATCC_199 EVMATIRDLAER-EIVLHSLREGIDSSNATGRMIAGVLASLAELELELGR
. : :* . * :.* * *
MMAR_2129|M.marinum_M ARIRRKMLQNAQAGLPHGSARPFGYEADK--ITVRESEAAVVREMVDRYL
MAV_3790|M.avium_104 ARIRRKMLQNAEKGLPHGPARPFGYEPDK--ITLRPEEAKIVREMVDRYL
Mb1612c|M.bovis_AF2122/97 ARQRRAARQKAERGHPN-WSKAFGYLPGPNGPEPDPRTAPLVKQAYADIL
Rv1586c|M.tuberculosis_H37Rv ARQRRAARQKAERGHPN-WSKAFGYLPGPNGPEPDPRTAPLVKQAYADIL
TH_3834|M.thermoresistible__bu ARQLRAAQQKAERGVPQ-WKRAFGFADG---YVADEITAPLVKEMYAHVL
Mvan_1448|M.vanbaalenii_PYR-1 ERRKRANVQRAANGDWVAARRPFGYTMDG---EPLEPEATAIRSAITDVL
Mflv_1983|M.gilvum_PYR-GCK ERTKVALAAKRARGERIGRPRLA--------------KPGVVRRIVMDRN
MAB_1820c|M.abscessus_ATCC_199 ERRAAARESRRARGQHIGRPKALDN--------------AKAALAQRMHL
* . * :
MMAR_2129|M.marinum_M AGQSLRSLTIWLNESQ----------------------ITPSVAKSWQTS
MAV_3790|M.avium_104 AGASIRSLTIWLSDTG----------------------VAPPASKSWQTT
Mb1612c|M.bovis_AF2122/97 AGASLGDVCRQWNDAG---------------------AFTITGR-PWTTT
Rv1586c|M.tuberculosis_H37Rv AGASLGDVCRQWNDAG---------------------AFTITGR-PWTTT
TH_3834|M.thermoresistible__bu AGGSLSGLARELNARGDWAWGQKWVKPKDDYGETIKSAEVVCQRQPWSAS
Mvan_1448|M.vanbaalenii_PYR-1 SGKSVRAVARDWNDAG---------------------LATTGKADKWTAT
Mflv_1983|M.gilvum_PYR-GCK AGLSFARIANALEAEG---------------------ILSPAGLPTWQSS
MAB_1820c|M.abscessus_ATCC_199 AGEPVLTIANTLGVSR---------------------------------A
:* .. : :
MMAR_2129|M.marinum_M AVRQVLSSGRIAGLREHRG---------EVIGPAVWPAIITPAERDRVLA
MAV_3790|M.avium_104 TVRNILASGRIAGLREHHG---------EVIGAAAWPAIITAGERDRILA
Mb1612c|M.bovis_AF2122/97 TLSKFLRKPRNAGLRAYKGARYGPVDRDAIVGKAQWSPLVDEATFWAAQA
Rv1586c|M.tuberculosis_H37Rv TLSKFLRKPRNAGLRAYKGARYGPVDRDAIVGKAQWSPLVDEATFWAAQA
TH_3834|M.thermoresistible__bu TLSLFLRSPRNAGLRTYN--RELVLDKDGQPVRGAWEPLVDEDTWRAVQS
Mvan_1448|M.vanbaalenii_PYR-1 SVRRVLLRPRYAALVVHQG---------KVVGPGSWTPLIDTDTHHGIVA
Mflv_1983|M.gilvum_PYR-GCK TVRRIYQSATVTTEMEKTA-------------------------------
MAB_1820c|M.abscessus_ATCC_199 TVYRVLAEDLHAGKEDQ---------------------------------
:: . :
MMAR_2129|M.marinum_M RMAARSVTKSR-TARTYLLSGLLRCRRCGNRLYSQARHS-----------
MAV_3790|M.avium_104 RMTARSVTKTR-APRTYLLSGMLRCGRCGNRLFSQARHN-----------
Mb1612c|M.bovis_AF2122/97 VLDAPGRAPGRKSVRRHLLTGLAGCGKCGNHLAGSYRTD-----------
Rv1586c|M.tuberculosis_H37Rv VLDAPGRAPGRKSVRRHLLTGLAGCGKCGNHLAGSYRTD-----------
TH_3834|M.thermoresistible__bu VLDAPGRAPGRKSVRQHLLTGVLVCGKCEGSLAGQWVMQPTGGEPGRSKA
Mvan_1448|M.vanbaalenii_PYR-1 YLNDPARKGKVGFERKYQGSGVYRCGVCGTPVITHMSSGGS---------
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2129|M.marinum_M -------NPQNRVRRYVCLKGPDHGGCGRLTVVAAPVEELLTEAVLTRLD
MAV_3790|M.avium_104 -------NPTNRVRRYVCLKGPDHGGCGRLTVVALPVEELLTDAVLTRLD
Mb1612c|M.bovis_AF2122/97 -------GQ----VVYVCK------ACHGVAILADNIEPILYHIVAERLA
Rv1586c|M.tuberculosis_H37Rv -------GQ----VVYVCK------ACHGVAILADNIEPILYHIVAERLA
TH_3834|M.thermoresistible__bu GRVKEPTGQKRHVITYSCK------TCRGVSMRAEHIEPLVYGVVGARLA
Mvan_1448|M.vanbaalenii_PYR-1 -------PNRVARRAYACP------NGFHVRRQGDGLDTYVDTIVIGRLS
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2129|M.marinum_M SAQLADALAGKAN-ADADVTALAAQVDTDQGRLDELAGLYADGAITAREW
MAV_3790|M.avium_104 SPQLAGALAGRSS-VDADVAALAAQLEADQARLDELAGLYAEGAVSAREW
Mb1612c|M.bovis_AF2122/97 MPDAVDLLRREIH-DAAEAETIRLELETLYGELDRLAVERAEGLLTARQV
Rv1586c|M.tuberculosis_H37Rv MPDAVDLLRREIH-DAAEAETIRLELETLYGELDRLAVERAEGLLTARQV
TH_3834|M.thermoresistible__bu EPDALDLLRSEQH-DVEAAEQVRQQRSALNQRLLEIADERADGLLTGQQA
Mvan_1448|M.vanbaalenii_PYR-1 QPDAAELLSTLSNSEGVDIGALHAQRTALQARQEELASLFADGAISAPQL
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2129|M.marinum_M IAARDPITERITAARRDIAAVTD---TTAVFELVGTGGALRTEWDGLDLG
MAV_3790|M.avium_104 IAARDPITDRIARARRDIAKATD---TSAVMDLVGCGEVLRGQWDDLDID
Mb1612c|M.bovis_AF2122/97 KISTDIVNAKITKLQARQQDQER---LRVFDGIPLGTPQVAGMIAELSPD
Rv1586c|M.tuberculosis_H37Rv KISTDIVNAKITKLQARQQDQER---LRVFDGIPLGTPQVAGMIAELSPD
TH_3834|M.thermoresistible__bu ARATARILDRLAALQLVDADQER---LRVLDGLPLGTPDAEGALEGLTPD
Mvan_1448|M.vanbaalenii_PYR-1 KLGSAKLTNALETLERDLAAATQGNPASALLQDVNGVAQLEGRWAELSPD
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2129|M.marinum_M RQQAIIKAVLDHAVIAPGTPGAR-RLDIDRVAPIWRV-
MAV_3790|M.avium_104 RQQAIIKSVLDHAVIAPGTPGSR-KLDINRVQPHWRI-
Mb1612c|M.bovis_AF2122/97 RFRAVLDVLAEVVVQPVGKSGR--IFNPERVQVNWR--
Rv1586c|M.tuberculosis_H37Rv RFRAVLDVLAEVVVQPVGKSGR--IFNPERVQVNWR--
TH_3834|M.thermoresistible__bu RFRAVLGVVCTITVLPIGRGRRKGVEHRDRLQIDWK--
Mvan_1448|M.vanbaalenii_PYR-1 LRGKVIDQLMTVTINRSPKGLRR--FDPDYVTVDWKQG
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------