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MPARKSAGQRVGVGSAAIYARISSDVEGTGLGVARQLEDCRKLAEDRGWPVGAEYVDNDVSAFSGKPRRE YARMLADLASGDRDAVIVYNLDRLHRRPVELEEFVTLCESVGVRDVATVTADIDLGNDDGLFMARIFAAF AAKESGRKSARIRRKMLQNAQAGLPHGSARPFGYEADKITVRESEAAVVREMVDRYLAGQSLRSLTIWLN ESQITPSVAKSWQTSAVRQVLSSGRIAGLREHRGEVIGPAVWPAIITPAERDRVLARMAARSVTKSRTAR TYLLSGLLRCRRCGNRLYSQARHSNPQNRVRRYVCLKGPDHGGCGRLTVVAAPVEELLTEAVLTRLDSAQ LADALAGKANADADVTALAAQVDTDQGRLDELAGLYADGAITAREWIAARDPITERITAARRDIAAVTDT TAVFELVGTGGALRTEWDGLDLGRQQAIIKAVLDHAVIAPGTPGARRLDIDRVAPIWRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2129 | - | - | 100% (479) | site-specific integrase |
| M. marinum M | MMAR_3124 | - | 7e-11 | 23.19% (526) | integrase |
| M. marinum M | MMAR_4443 | - | 5e-09 | 29.55% (220) | site-specific recombinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1612c | - | 2e-53 | 33.27% (496) | phiRv1 integrase |
| M. gilvum PYR-GCK | Mflv_3036 | - | 1e-10 | 23.56% (522) | recombinase |
| M. tuberculosis H37Rv | Rv1586c | - | 2e-53 | 33.27% (496) | phiRv1 integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2101 | - | 1e-09 | 24.45% (499) | recombinase |
| M. avium 104 | MAV_3790 | - | 0.0 | 79.75% (479) | integrase/recombinase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3834 | - | 1e-26 | 28.64% (419) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1448 | - | 9e-56 | 32.84% (472) | recombinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2129|M.marinum_M MPARKSAGQRVGVGSAAIYARISSDVEG--TGLGVARQLEDCRKLAEDRG
MAV_3790|M.avium_104 MGKAKTPAQRVGARSAAIYARISADVEG--TGLGVARQLEDCRKLAAERG
Mb1612c|M.bovis_AF2122/97 -------MRYTTPVRAAVYLRISEDRSG--EQLGVARQREDCLKLCGQRK
Rv1586c|M.tuberculosis_H37Rv -------MRYTTPVRAAVYLRISEDRSG--EQLGVARQREDCLKLCGQRK
TH_3834|M.thermoresistible__bu --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 -------------MRAVIYTRISDDQAG--RGLGVARQLEDCQALADKLG
Mflv_3036|M.gilvum_PYR-GCK -----------MSLRFAFYGRVSTEDAQDPDASRSWQKRRATDLITPHGG
MAB_2101|M.abscessus_ATCC_1997 -----------MSLRFAFYGRVSTEDAQDPEASRSWQKRRAIDLISPHGG
MMAR_2129|M.marinum_M WPVGAEYVDNDVSAFSGKPRREYARMLADLASGD--RDAVIVYNLDRLHR
MAV_3790|M.avium_104 WPIGDEYVDNDVSAYSGKPRREYARMLDDLKSGA--RDAVIVYNLDRLHR
Mb1612c|M.bovis_AF2122/97 WVPVEYLDN-DVSASTGKRRPAYEQMLADITAGK--IAAVVAWDLDRLHR
Rv1586c|M.tuberculosis_H37Rv WVPVEYLDN-DVSASTGKRRPAYEQMLADITAGK--IAAVVAWDLDRLHR
TH_3834|M.thermoresistible__bu -------------------------MLADIRDGL--VRAVVVWDLDRLHR
Mvan_1448|M.vanbaalenii_PYR-1 WQVVNHFDDNDISAYSGKRRPGFEAMLEAMKAGQ--FDALLCFHTDRLYR
Mflv_3036|M.gilvum_PYR-GCK VLAADYFDVGQSRSLPWKRRPEASRLLIDVASRDRNFDAVVIGEPARAFY
MAB_2101|M.abscessus_ATCC_1997 VLAADYFDIGQSRSLPWKRRPEASRLLADVTSRDRGFDAVVIGEPARAFY
:* : *:: . * .
MMAR_2129|M.marinum_M RPVELEEFVTLCESVGVRDVATVTADIDLGNDDGLFMARIFAAFAAKESG
MAV_3790|M.avium_104 RPVELEDFVTLCESVGVRDVATVTADIDLGNDDGLFMARIFAAFAAKESG
Mb1612c|M.bovis_AF2122/97 RPIELEAFMSLADEKRLALATVAG-DVDLATPQGRLVARLKGSVAAHETE
Rv1586c|M.tuberculosis_H37Rv RPIELEAFMSLADEKRLALATVAG-DVDLATPQGRLVARLKGSVAAHETE
TH_3834|M.thermoresistible__bu RPLELEGFMALADERGLKLATVSG-DVDLSTAQGRLIARLKGSVAAHEIE
Mvan_1448|M.vanbaalenii_PYR-1 NMSDLERVIELADARRVEIRTVQGGTLDLSTSAGRMVARILGSVARQESE
Mflv_3036|M.gilvum_PYR-GCK GPQFALTFPVLTHHGVGLWVPEVGGAVDPGSEAHDLVMTLFGGMSKGERA
MAB_2101|M.abscessus_ATCC_1997 GPQFALTFPVLTHYGVGLWVPEVGGAVDPGSEAHDLVMTLFGGMSKGERA
. * . . :* .. :: : ...: *
MMAR_2129|M.marinum_M RKSARIRRKMLQNAQAGL-PHGSARPFGYEADK-----------------
MAV_3790|M.avium_104 RKSARIRRKMLQNAEKGL-PHGPARPFGYEPDK-----------------
Mb1612c|M.bovis_AF2122/97 HKKARQRRAARQKAERG--HPNWSKAFGYLPGPN----------------
Rv1586c|M.tuberculosis_H37Rv HKKARQRRAARQKAERG--HPNWSKAFGYLPGPN----------------
TH_3834|M.thermoresistible__bu HKRARQLRAAQQKAERG--VPQWKRAFGFADG------------------
Mvan_1448|M.vanbaalenii_PYR-1 HSSERRKRANVQRAANGD-WVAARRPFGYTMD------------------
Mflv_3036|M.gilvum_PYR-GCK RIQMRVRTAMSALAQDTNRYLGGRPPYGYRLVDAGPHPNAAKANLGQRLH
MAB_2101|M.abscessus_ATCC_1997 RIQMRVRTAMSALAQDTTRYLGGRPPYGYQLVDAGPHPNPAKASLGQRLH
: * * .:*:
MMAR_2129|M.marinum_M -ITVRESEAAVVREMVDRYLAGQSLRSLTIWLNESQ--------------
MAV_3790|M.avium_104 -ITLRPEEAKIVREMVDRYLAGASIRSLTIWLSDTG--------------
Mb1612c|M.bovis_AF2122/97 GPEPDPRTAPLVKQAYADILAGASLGDVCRQWNDAG--------------
Rv1586c|M.tuberculosis_H37Rv GPEPDPRTAPLVKQAYADILAGASLGDVCRQWNDAG--------------
TH_3834|M.thermoresistible__bu -YVADEITAPLVKEMYAHVLAGGSLSGLARELNARGDWAWGQKWVKPKDD
Mvan_1448|M.vanbaalenii_PYR-1 -GEPLEPEATAIRSAITDVLSGKSVRAVARDWNDAG--------------
Mflv_3036|M.gilvum_PYR-GCK RLEPDPATSSVVERIYRMYADGAGLRYIAQELTDDG-----------VPS
MAB_2101|M.abscessus_ATCC_1997 RLEPDPETAPTVERIYRMYADGAGLRFIAQQLTDDG-----------VPS
: :. * .: : .
MMAR_2129|M.marinum_M --------ITPSVAKSWQTSAVRQVLSSGRIAGLREHRG-----------
MAV_3790|M.avium_104 --------VAPPASKSWQTTTVRNILASGRIAGLREHHG-----------
Mb1612c|M.bovis_AF2122/97 -------AFTITGR-PWTTTTLSKFLRKPRNAGLRAYKGA----------
Rv1586c|M.tuberculosis_H37Rv -------AFTITGR-PWTTTTLSKFLRKPRNAGLRAYKGA----------
TH_3834|M.thermoresistible__bu YGETIKSAEVVCQRQPWSASTLSLFLRSPRNAGLRTYN------------
Mvan_1448|M.vanbaalenii_PYR-1 -------LATTGKADKWTATSVRRVLLRPRYAALVVHQG-----------
Mflv_3036|M.gilvum_PYR-GCK PSQYDPARNRHRDPRGWSHSAIRAILDNPTYLGVRVWGKQEKYEVLVDPD
MAB_2101|M.abscessus_ATCC_1997 PSQYDPARNRHRDPRGWSHSAIRAILDNPAYRGIRVWGKQEKYEVLLNPD
* ::: .* .:
MMAR_2129|M.marinum_M ------------------EVIGPAVWPAIITPAERDRVLARMA---ARS-
MAV_3790|M.avium_104 ------------------EVIGAAAWPAIITAGERDRILARMT---ARS-
Mb1612c|M.bovis_AF2122/97 ----------RYGPVDRDAIVGKAQWSPLVDEATFWAAQAVLD---APGR
Rv1586c|M.tuberculosis_H37Rv ----------RYGPVDRDAIVGKAQWSPLVDEATFWAAQAVLD---APGR
TH_3834|M.thermoresistible__bu ----------RELVLDKDGQPVRGAWEPLVDEDTWRAVQSVLD---APGR
Mvan_1448|M.vanbaalenii_PYR-1 ------------------KVVGPGSWTPLIDTDTHHGIVAYLN---DPAR
Mflv_3036|M.gilvum_PYR-GCK DVAAGYETRMRWRDQADWIAPDRRTHEALIHDDLAQAVRLRTLARRGPGL
MAB_2101|M.abscessus_ATCC_1997 DVAAGYETRMRWRDRADWIAPDRRTHEELIPDELAQAVRLRMQARRGPGR
:: .
MMAR_2129|M.marinum_M VTKSRTARTYLLSGLLRCRRCGNRLYSQARHSNP------------QNRV
MAV_3790|M.avium_104 VTKTRAPRTYLLSGMLRCGRCGNRLFSQARHNNP------------TNRV
Mb1612c|M.bovis_AF2122/97 APGRKSVRRHLLTGLAGCGKCGNHLAGSYRTD------------------
Rv1586c|M.tuberculosis_H37Rv APGRKSVRRHLLTGLAGCGKCGNHLAGSYRTD------------------
TH_3834|M.thermoresistible__bu APGRKSVRQHLLTGVLVCGKCEGSLAGQWVMQPTGGEPGRSKAGRVKEPT
Mvan_1448|M.vanbaalenii_PYR-1 KGKVGFERKYQGSGVYRCGVCGTPVITHMSSGGS----------------
Mflv_3036|M.gilvum_PYR-GCK VCSRESIVPYALRGLLFCAACGRRMQGAARVGKQ------TTRILYRCEL
MAB_2101|M.abscessus_ATCC_1997 VCSRESTVPYALRGLLFCAACGRRMQGAARPGKQ------TTRILYRCEF
: *: * * :
MMAR_2129|M.marinum_M RRYVCLKGPDHGGCGRLTVVAAPVEELLTEAVLTRLDSAQLADALAGKA-
MAV_3790|M.avium_104 RRYVCLKGPDHGGCGRLTVVALPVEELLTDAVLTRLDSPQLAGALAGRS-
Mb1612c|M.bovis_AF2122/97 GQ----VVYVCKACHGVAILADNIEPILYHIVAERLAMPDAVDLLRREI-
Rv1586c|M.tuberculosis_H37Rv GQ----VVYVCKACHGVAILADNIEPILYHIVAERLAMPDAVDLLRREI-
TH_3834|M.thermoresistible__bu GQKRHVITYSCKTCRGVSMRAEHIEPLVYGVVGARLAEPDALDLLRSEQ-
Mvan_1448|M.vanbaalenii_PYR-1 PNRVARRAYACPNGFHVRRQGDGLDTYVDTIVIGRLSQPDAAELLSTLSN
Mflv_3036|M.gilvum_PYR-GCK GKSRSVPADLSDHPRTVYLREDEVTVQLDEWIATLADPDDLARGQDADS-
MAB_2101|M.abscessus_ATCC_1997 GKSRSVPVDLSDHPRTVYLREDAVTARLDEWIATLADPEDLARGQDVDP-
. : : : : :
MMAR_2129|M.marinum_M NADADVTALAAQVDTDQGRLDELAGLYADGAITAREWIAARDPITER-IT
MAV_3790|M.avium_104 SVDADVAALAAQLEADQARLDELAGLYAEGAVSAREWIAARDPITDR-IA
Mb1612c|M.bovis_AF2122/97 HDAAEAETIRLELETLYGELDRLAVERAEGLLTARQVKISTDIVNAK-IT
Rv1586c|M.tuberculosis_H37Rv HDAAEAETIRLELETLYGELDRLAVERAEGLLTARQVKISTDIVNAK-IT
TH_3834|M.thermoresistible__bu HDVEAAEQVRQQRSALNQRLLEIADERADGLLTGQQAARATARILDR-LA
Mvan_1448|M.vanbaalenii_PYR-1 SEGVDIGALHAQRTALQARQEELASLFADGAISAPQLKLGSAKLTNA-LE
Mflv_3036|M.gilvum_PYR-GCK AARTGYAALQRQLSEANRKVAALVNAVESGVAVEDLTAALRRRTAERDEL
MAB_2101|M.abscessus_ATCC_1997 AAGPGYAALQRQLSEANAKVAALITAVESGVAVEDLTAALRQRTAERDEL
: : . : .*
MMAR_2129|M.marinum_M AARRDIAAVTD---TTAVFELVGTGGALRTEWDGLDLGRQQAIIKAVLDH
MAV_3790|M.avium_104 RARRDIAKATD---TSAVMDLVGCGEVLRGQWDDLDIDRQQAIIKSVLDH
Mb1612c|M.bovis_AF2122/97 KLQARQQDQER---LRVFDGIPLGTPQVAGMIAELSPDRFRAVLDVLAEV
Rv1586c|M.tuberculosis_H37Rv KLQARQQDQER---LRVFDGIPLGTPQVAGMIAELSPDRFRAVLDVLAEV
TH_3834|M.thermoresistible__bu ALQLVDADQER---LRVLDGLPLGTPDAEGALEGLTPDRFRAVLGVVCTI
Mvan_1448|M.vanbaalenii_PYR-1 TLERDLAAATQGNPASALLQDVNGVAQLEGRWAELSPDLRGKVIDQLMTV
Mflv_3036|M.gilvum_PYR-GCK KARLERAERPLAMSAAQISELVEELGGLAAVLGEATGAERAQVYASLGLR
MAB_2101|M.abscessus_ATCC_1997 RARVERVERPRAMCAAEISELVKELGGLSVILGAATGAERAEVYASLGLR
. . : :
MMAR_2129|M.marinum_M AVIAPGTPGAR-RLDIDRVAPIWRV--
MAV_3790|M.avium_104 AVIAPGTPGSR-KLDINRVQPHWRI--
Mb1612c|M.bovis_AF2122/97 VVQPVGKSGR--IFNPERVQVNWR---
Rv1586c|M.tuberculosis_H37Rv VVQPVGKSGR--IFNPERVQVNWR---
TH_3834|M.thermoresistible__bu TVLPIGRGRRKGVEHRDRLQIDWK---
Mvan_1448|M.vanbaalenii_PYR-1 TINRSPKGLR--RFDPDYVTVDWKQG-
Mflv_3036|M.gilvum_PYR-GCK LDYDPHLRQVTATADLSRVAGCVRGGT
MAB_2101|M.abscessus_ATCC_1997 LDYDPHLRRVTATADLSRVAGCVRGGT
. . : :