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PNDVFIYDALRTPRGRNRGGSLHGVKPIDLVVGLLDALQQRNPGLDAGRIDDLVLGCVTPIGEQGADIAR IAALAAGLPETVAGVQLNRFCASGLEAVNIAAQKIASGWETLVIAGGVESMSRVPMGSDGGAWANDPKTN LTTGYVPQGVGADLIATLEGFSRHDVDSYAVESQSRAAKAWATGAFERSVVPVLDANGLTVLARDEHLRP GSTVEALSKLSPAFATLGQQFGFDDVALQKYHWIERIDHVHTGANSSGIVDGAALVVLGNEQIGQDMGLI PRARILATAVSGSDPTIMLTGPAPASRKALAVAGLGIDDIDLFEINEAFASVVLRFMKDLGLPHDIVNVN GGAIALGHPLGATGAMLISTVVDELERRDQRRGLITLCVGGGMGIATIVERV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0916 | - | - | 100% (403) | acetyl-CoA acetyltransferases |
| M. vanbaalenii PYR-1 | Mvan_5067 | - | e-165 | 68.49% (403) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2617 | - | 4e-80 | 43.49% (407) | acetyl-CoA acetyltransferases |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0882 | fadA | 1e-163 | 67.99% (403) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_1691 | - | 1e-165 | 69.23% (403) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv0859 | fadA | 1e-162 | 67.74% (403) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_02162 | fadA | 1e-162 | 67.25% (403) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0850 | - | 1e-161 | 67.75% (400) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_4677 | fadA | 1e-160 | 67.00% (403) | acyl-CoA thiolase FadA |
| M. avium 104 | MAV_0980 | - | 1e-166 | 69.73% (403) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5721 | - | 1e-167 | 70.72% (403) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0255 | - | 3e-73 | 41.15% (401) | acetyl-CoA acetyltransferase |
| M. ulcerans Agy99 | MUL_0296 | fadA | 1e-159 | 66.75% (403) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4677|M.marinum_M MTDLNPNFCEQEVDMSEEAFIYEAIRTPRGKQKNGSLNEVKPISLVVGLI
MUL_0296|M.ulcerans_Agy99 --------------MSEEAFIYEAIRTPRGKQKYGSLNEVKPISLVVGLI
Mb0882|M.bovis_AF2122/97 --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLI
Rv0859|M.tuberculosis_H37Rv --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLI
MLBr_02162|M.leprae_Br4923 --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLV
MAV_0980|M.avium_104 --------------MSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLV
Mflv_1691|M.gilvum_PYR-GCK --------------MSEEAFIYEAIRTPRGKQRGGALNEIKPVNLVVGLI
MSMEG_5721|M.smegmatis_MC2_155 --------------MSEEAFIYEAIRTPRGKQRGGALNEIKPVNLVVGLI
MAB_0850|M.abscessus_ATCC_1997 ---------------MTEAFIYEAVRTPRGKQRGGALNEIKPLNLVVGLI
Mvan_0916|M.vanbaalenii_PYR-1 --------------MPNDVFIYDALRTPRGRNRGGSLHGVKPIDLVVGLL
TH_0255|M.thermoresistible__bu ---------------MRETVIVEAVRTAVGK-RNGALADVHAADLSAVVL
:..* :*:**. *: : *:* ::. .* . ::
MMAR_4677|M.marinum_M EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV
MUL_0296|M.ulcerans_Agy99 EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV
Mb0882|M.bovis_AF2122/97 DELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV
Rv0859|M.tuberculosis_H37Rv DELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV
MLBr_02162|M.leprae_Br4923 EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGV
MAV_0980|M.avium_104 DELRRRYPDLDETLISDMILGVVSPVGDQGGDIARTAVLAAGLPETTGGV
Mflv_1691|M.gilvum_PYR-GCK DEMRTRFPDLDENLISDLILGVVSPVGDQGGDIARTAGLVAKLPETTGGV
MSMEG_5721|M.smegmatis_MC2_155 DELRVRFPNLDETLISDLVLGVVSPVGDQGGDIARTATLVANLPETTGGV
MAB_0850|M.abscessus_ATCC_1997 EEIRHRHPDLDENLISDVVLGVVSPVGDQGGDIARTAVLAAGLPDTTGGV
Mvan_0916|M.vanbaalenii_PYR-1 DALQQRNPGLDAGRIDDLVLGCVTPIGEQGADIARIAALAAGLPETVAGV
TH_0255|M.thermoresistible__bu SELVER-AGIDPELIDDVIWGCVSQVGDQSSNIGRYAVLAAGWPETIPGT
. : * ..:* *.*:: * *: :*:*..:*.* : *.: * * *.
MMAR_4677|M.marinum_M QLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGAD---GGA
MUL_0296|M.ulcerans_Agy99 QLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGAD---GGA
Mb0882|M.bovis_AF2122/97 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
Rv0859|M.tuberculosis_H37Rv QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
MLBr_02162|M.leprae_Br4923 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
MAV_0980|M.avium_104 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
Mflv_1691|M.gilvum_PYR-GCK QLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
MSMEG_5721|M.smegmatis_MC2_155 QLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
MAB_0850|M.abscessus_ATCC_1997 QLNRFCASGLEAINIGAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGA
Mvan_0916|M.vanbaalenii_PYR-1 QLNRFCASGLEAVNIAAQKIASGWETLVIAGGVESMSRVPMGSD---GGA
TH_0255|M.thermoresistible__bu TVNRACGSSQQALDFAVHAVMSGQQDVVVAGGVEVMSRVPLGAARATGMP
:** *.*. :*:: ..: : ** : :*:***** *****:*: * .
MMAR_4677|M.marinum_M MGLDPVTNYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQEKAAEAWS
MUL_0296|M.ulcerans_Agy99 MGLDPVTNYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQEKAAEAWS
Mb0882|M.bovis_AF2122/97 MGLDPATNYDVMFVPQGIGADLIATIEGFSREDVDAYALRSQQKAAEAWS
Rv0859|M.tuberculosis_H37Rv MGLDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQQKAAEAWS
MLBr_02162|M.leprae_Br4923 MGLDPATNYDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWS
MAV_0980|M.avium_104 WATDPETNYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQKAAAAWS
Mflv_1691|M.gilvum_PYR-GCK WAADPETNYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQERAAAAWS
MSMEG_5721|M.smegmatis_MC2_155 WAGDPETNYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQERAAAAWS
MAB_0850|M.abscessus_ATCC_1997 WASDPATNYDVSFVPQGIGADLIATIEGFTRDDVDAYAARSQERAAAAWS
Mvan_0916|M.vanbaalenii_PYR-1 WANDPKTNLTTGYVPQGVGADLIATLEGFSRHDVDSYAVESQSRAAKAWA
TH_0255|M.thermoresistible__bu YGPKVLERYDNFGFNQGISAELIAERWNLSRTRLDEYSAQSHERAAAAQS
. . . . *.:.*:*** .::* :* *: .*:.:** * :
MMAR_4677|M.marinum_M GGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAFEGLAAMGG
MUL_0296|M.ulcerans_Agy99 GGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAFEGLAAMGG
Mb0882|M.bovis_AF2122/97 GGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGG
Rv0859|M.tuberculosis_H37Rv GGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGG
MLBr_02162|M.leprae_Br4923 GGYFAKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLKPAFEGLAAMGG
MAV_0980|M.avium_104 GGYFAKSVVPVRDQNGLVILDHDEHMRPDTTMEGLAKLKTAFDGVGEMGG
Mflv_1691|M.gilvum_PYR-GCK GGYFAKSVVPVKDQNGLVVLDHDEHIRPGTTIESLGKLKSAFEGVGAMGG
MSMEG_5721|M.smegmatis_MC2_155 GGYFSKSVVPVKDQNGLVVLDHDEHMRPGTTVESLGKLKPAFEGVGAMGG
MAB_0850|M.abscessus_ATCC_1997 GGYFAKSVVPVKDQNGLLVLDHDEHMRPGTTAADLGKLKPAFEGLAALGG
Mvan_0916|M.vanbaalenii_PYR-1 TGAFERSVVPVLDANGLTVLARDEHLRPGSTVEALSKLSPAFATLGQQFG
TH_0255|M.thermoresistible__bu SGAFKDQIVPVFTDD--AVVTEDEGIRRGTTVEKLATLKPAFT-------
* * .:*** : :: .** :* :: *..*..**
MMAR_4677|M.marinum_M FDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAGAAINATPR
MUL_0296|M.ulcerans_Agy99 FDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAGAAINATPR
Mb0882|M.bovis_AF2122/97 FDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPR
Rv0859|M.tuberculosis_H37Rv FDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPR
MLBr_02162|M.leprae_Br4923 FDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLTPR
MAV_0980|M.avium_104 FDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPR
Mflv_1691|M.gilvum_PYR-GCK FDDVALQKYHFVEKINHVHTGGNSSGIVDGAALVLIGSESAGTSQGLTPR
MSMEG_5721|M.smegmatis_MC2_155 FDDVALQKYHSIEKINHVHTGGNSSGIVDGAALVLIGSESAGKAAGLTPR
MAB_0850|M.abscessus_ATCC_1997 FDDVARIKYHYVEKINHVHTGGNSSGIVDGAALVLIGSEEAGKSQGLTPR
Mvan_0916|M.vanbaalenii_PYR-1 FDDVALQKYHWIERIDHVHTGANSSGIVDGAALVVLGNEQIGQDMGLIPR
TH_0255|M.thermoresistible__bu --------------ENGVIHAGNSSQISDGAAALLVMTAETAVTLGLTPI
: * ..*** * **** ::: . . . *
MMAR_4677|M.marinum_M ARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFELNEAFASV
MUL_0296|M.ulcerans_Agy99 ARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFELNEAFASV
Mb0882|M.bovis_AF2122/97 ARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASV
Rv0859|M.tuberculosis_H37Rv ARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASV
MLBr_02162|M.leprae_Br4923 ARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASV
MAV_0980|M.avium_104 ARIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASV
Mflv_1691|M.gilvum_PYR-GCK ARIVATATSGADPVIMLTGPTPATKKVLDRAGLTVDDIDLFELNEAFASV
MSMEG_5721|M.smegmatis_MC2_155 ARVVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASV
MAB_0850|M.abscessus_ATCC_1997 ARIVATATSGSEPLIMLTGPTPATKKVLDRAGLTVDDIDLFELNEAFASV
Mvan_0916|M.vanbaalenii_PYR-1 ARILATAVSGSDPTIMLTGPAPASRKALAVAGLGIDDIDLFEINEAFASV
TH_0255|M.thermoresistible__bu VRYRAGAVTGADPVLMLTGPIPATEKVLRKTGLNIDDIGVFEVNEAFAPV
.* * *.:*::* :***** **:.*.* :** :***.:**:*****.*
MMAR_4677|M.marinum_M VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARR
MUL_0296|M.ulcerans_Agy99 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARR
Mb0882|M.bovis_AF2122/97 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARR
Rv0859|M.tuberculosis_H37Rv VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARR
MLBr_02162|M.leprae_Br4923 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERCNARR
MAV_0980|M.avium_104 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRNARR
Mflv_1691|M.gilvum_PYR-GCK VLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGARR
MSMEG_5721|M.smegmatis_MC2_155 VLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGARR
MAB_0850|M.abscessus_ATCC_1997 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRGLKR
Mvan_0916|M.vanbaalenii_PYR-1 VLRFMKDLGLPHDIVNVNGGAIALGHPLGATGAMLISTVVDELERRDQRR
TH_0255|M.thermoresistible__bu PLAWQAETGADPAKLNPLGGAIALGHPLGASGAVLMTRMVHHMRANGIRY
* : : . :* *****:******:**:: :*..:. . :
MMAR_4677|M.marinum_M ALVTLCIGGGMGVATIIERV-
MUL_0296|M.ulcerans_Agy99 ALVTLCIGGGMGAATIIERV-
Mb0882|M.bovis_AF2122/97 ALITLCIGGGMGVATIIERV-
Rv0859|M.tuberculosis_H37Rv ALITLCIGGGMGVATIIERV-
MLBr_02162|M.leprae_Br4923 ALVTLCIGAGMGVATIIERV-
MAV_0980|M.avium_104 ALITLCIGGGMGVATIIERV-
Mflv_1691|M.gilvum_PYR-GCK ALITLCVGGGMGVATIIERV-
MSMEG_5721|M.smegmatis_MC2_155 ALITLCVGGGMGVATIIERV-
MAB_0850|M.abscessus_ATCC_1997 ALITLCVGGGMGVATIIERV-
Mvan_0916|M.vanbaalenii_PYR-1 GLITLCVGGGMGIATIVERV-
TH_0255|M.thermoresistible__bu GLQTMCEGGGTANATVVELLA
.* *:* *.* . **::* :