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MSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILGVVSPVGDQGGDIA RTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGAWATDPET NYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQQKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMR PDTTMEGLAKLKTAFDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGL TPRARIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLNV NGGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATIIERV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0980 | - | - | 100% (403) | acetyl-CoA acetyltransferase |
M. avium 104 | MAV_2702 | - | e-173 | 74.56% (401) | acetyl-CoA acetyltransferase |
M. avium 104 | MAV_4185 | - | 6e-85 | 46.32% (408) | FadA6_4 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0882 | fadA | 0.0 | 90.57% (403) | acetyl-CoA acetyltransferase |
M. gilvum PYR-GCK | Mflv_1691 | - | 0.0 | 89.83% (403) | acetyl-CoA acetyltransferase |
M. tuberculosis H37Rv | Rv0859 | fadA | 0.0 | 90.32% (403) | acetyl-CoA acetyltransferase |
M. leprae Br4923 | MLBr_02162 | fadA | 0.0 | 89.33% (403) | acetyl-CoA acetyltransferase |
M. abscessus ATCC 19977 | MAB_0850 | - | 0.0 | 86.00% (400) | acetyl-CoA acetyltransferase |
M. marinum M | MMAR_4677 | fadA | 0.0 | 87.84% (403) | acyl-CoA thiolase FadA |
M. smegmatis MC2 155 | MSMEG_5721 | - | 0.0 | 89.33% (403) | acetyl-CoA acetyltransferase |
M. thermoresistible (build 8) | TH_0166 | fadA6 | 7e-77 | 43.07% (411) | PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 |
M. ulcerans Agy99 | MUL_0296 | fadA | 0.0 | 87.34% (403) | acetyl-CoA acetyltransferase |
M. vanbaalenii PYR-1 | Mvan_5067 | - | 0.0 | 89.08% (403) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0882|M.bovis_AF2122/97 --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLI Rv0859|M.tuberculosis_H37Rv --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLI MLBr_02162|M.leprae_Br4923 --------------MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLV MMAR_4677|M.marinum_M MTDLNPNFCEQEVDMSEEAFIYEAIRTPRGKQKNGSLNEVKPISLVVGLI MUL_0296|M.ulcerans_Agy99 --------------MSEEAFIYEAIRTPRGKQKYGSLNEVKPISLVVGLI MAV_0980|M.avium_104 --------------MSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLV Mflv_1691|M.gilvum_PYR-GCK --------------MSEEAFIYEAIRTPRGKQRGGALNEIKPVNLVVGLI MSMEG_5721|M.smegmatis_MC2_155 --------------MSEEAFIYEAIRTPRGKQRGGALNEIKPVNLVVGLI Mvan_5067|M.vanbaalenii_PYR-1 --------------MSEEAFIYEAIRTPRGKQRNGALNEIKPVNLVVGLI MAB_0850|M.abscessus_ATCC_1997 ---------------MTEAFIYEAVRTPRGKQRGGALNEIKPLNLVVGLI TH_0166|M.thermoresistible__bu -------------MAMTEAYIVDAVRTPVGK-RNGGLSGAHPADMAAHVI **:* :*:*** ** : *.* :* .:.. :: Mb0882|M.bovis_AF2122/97 DELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV Rv0859|M.tuberculosis_H37Rv DELRKRHPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV MLBr_02162|M.leprae_Br4923 EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGV MMAR_4677|M.marinum_M EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV MUL_0296|M.ulcerans_Agy99 EELRKRNPDLDENLISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGV MAV_0980|M.avium_104 DELRRRYPDLDETLISDMILGVVSPVGDQGGDIARTAVLAAGLPETTGGV Mflv_1691|M.gilvum_PYR-GCK DEMRTRFPDLDENLISDLILGVVSPVGDQGGDIARTAGLVAKLPETTGGV MSMEG_5721|M.smegmatis_MC2_155 DELRVRFPNLDETLISDLVLGVVSPVGDQGGDIARTATLVANLPETTGGV Mvan_5067|M.vanbaalenii_PYR-1 DEMRVRFPDLDENLISDLILGCVSPVGDQGGDIARTAGLVAGLPDTTGGF MAB_0850|M.abscessus_ATCC_1997 EEIRHRHPDLDENLISDVVLGVVSPVGDQGGDIARTAVLAAGLPDTTGGV TH_0166|M.thermoresistible__bu KTLVGRH-DFDPAAIDDVIFGCLDNIGSQAGDIARTAALAAGLPESVPGV . : * ::* *.*:::* :. :*.*.*****:: *.: :* : *. Mb0882|M.bovis_AF2122/97 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- Rv0859|M.tuberculosis_H37Rv QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- MLBr_02162|M.leprae_Br4923 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- MMAR_4677|M.marinum_M QLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGADGGA--- MUL_0296|M.ulcerans_Agy99 QLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGADGGA--- MAV_0980|M.avium_104 QLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- Mflv_1691|M.gilvum_PYR-GCK QLNRFCASGLEAVNMAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- MSMEG_5721|M.smegmatis_MC2_155 QLNRFCASGLEAVNIAAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- Mvan_5067|M.vanbaalenii_PYR-1 QLNRFCASGLEAVNLGAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- MAB_0850|M.abscessus_ATCC_1997 QLNRFCASGLEAINIGAQKVRSGWDDLVLAGGVESMSRVPMGSDGGA--- TH_0166|M.thermoresistible__bu TIDRQCGSAQQAVHFAAQGVMSGTVDLIVAGGVQKMSQFPILSAFAAGEP ::* *.*. :*:: .** * ** **::****:.**:.*: : .* Mb0882|M.bovis_AF2122/97 -MGLDPAT-------NYDVMFVPQGIGADLIATIEGFSREDVDAYALRSQ Rv0859|M.tuberculosis_H37Rv -MGLDPAT-------NYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQ MLBr_02162|M.leprae_Br4923 -MGLDPAT-------NYDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQ MMAR_4677|M.marinum_M -MGLDPVT-------NYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQ MUL_0296|M.ulcerans_Agy99 -MGLDPVT-------NYDVMFVPQGIGADLIATIEGFSRDDVDAYALRSQ MAV_0980|M.avium_104 -WATDPET-------NYRIGFVPQGIGADLIATLEGFSREDVDAYALRSQ Mflv_1691|M.gilvum_PYR-GCK -WAADPET-------NYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQ MSMEG_5721|M.smegmatis_MC2_155 -WAGDPET-------NYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQ Mvan_5067|M.vanbaalenii_PYR-1 -WAGDPET-------NYRIGFVPQGIGADLIATIEGFSREDVDAYAARSQ MAB_0850|M.abscessus_ATCC_1997 -WASDPAT-------NYDVSFVPQGIGADLIATIEGFTRDDVDAYAARSQ TH_0166|M.thermoresistible__bu YGATDPWTGCEGWQARYGDQEISQFRGAEMIAEHWKLSREDNEKFALESH . ** * .* :.* **::** ::*:* : :* .*: Mb0882|M.bovis_AF2122/97 QKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAF Rv0859|M.tuberculosis_H37Rv QKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAF MLBr_02162|M.leprae_Br4923 EKAAAAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLKPAF MMAR_4677|M.marinum_M EKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAF MUL_0296|M.ulcerans_Agy99 EKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPETTKEGLGKLKSAF MAV_0980|M.avium_104 QKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTTMEGLAKLKTAF Mflv_1691|M.gilvum_PYR-GCK ERAAAAWSGGYFAKSVVPVKDQNGLVVLDHDEHIRPGTTIESLGKLKSAF MSMEG_5721|M.smegmatis_MC2_155 ERAAAAWSGGYFSKSVVPVKDQNGLVVLDHDEHMRPGTTVESLGKLKPAF Mvan_5067|M.vanbaalenii_PYR-1 ERAAAAWAGGYFAKSVVPVKDQNGLVVLDHDEHMRPGSTVESLGKLKTAF MAB_0850|M.abscessus_ATCC_1997 ERAAAAWSGGYFAKSVVPVKDQNGLLVLDHDEHMRPGTTAADLGKLKPAF TH_0166|M.thermoresistible__bu RRAVAAIEAGYFDKEITPYADAT------VDEGPRPDTSLEKMASLPTLI .:*. * .*** *.:.* * . ** ** :: :..* . : Mb0882|M.bovis_AF2122/97 EGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAG Rv0859|M.tuberculosis_H37Rv EGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAG MLBr_02162|M.leprae_Br4923 EGLAAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVG MMAR_4677|M.marinum_M EGLAAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAG MUL_0296|M.ulcerans_Agy99 EGLAAMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAAIVMVGSEKAG MAV_0980|M.avium_104 DGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAG Mflv_1691|M.gilvum_PYR-GCK EGVGAMGGFDDVALQKYHFVEKINHVHTGGNSSGIVDGAALVLIGSESAG MSMEG_5721|M.smegmatis_MC2_155 EGVGAMGGFDDVALQKYHSIEKINHVHTGGNSSGIVDGAALVLIGSESAG Mvan_5067|M.vanbaalenii_PYR-1 DGIGAMGGFDDVALQKYHFVEKINHVHTGGNSSGIVDGAALLLIGSEAAG MAB_0850|M.abscessus_ATCC_1997 EGLAALGGFDDVARIKYHYVEKINHVHTGGNSSGIVDGAALVLIGSEEAG TH_0166|M.thermoresistible__bu EG----G------------------VLTAAVASQISDGAAALLVASKDAV :* * * *.. :* * **** :::.* . Mb0882|M.bovis_AF2122/97 KLQGLTPRARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFE Rv0859|M.tuberculosis_H37Rv KLQGLTPRARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFE MLBr_02162|M.leprae_Br4923 KSQGLTPRARMVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFE MMAR_4677|M.marinum_M AAINATPRARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFE MUL_0296|M.ulcerans_Agy99 AAINATPRARIVATATSGADPVIMLTGPTPAARKVLDRAGLTVDDIDLFE MAV_0980|M.avium_104 KSQGLTPRARIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFE Mflv_1691|M.gilvum_PYR-GCK TSQGLTPRARIVATATSGADPVIMLTGPTPATKKVLDRAGLTVDDIDLFE MSMEG_5721|M.smegmatis_MC2_155 KAAGLTPRARVVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFE Mvan_5067|M.vanbaalenii_PYR-1 KSQGLTPRARIVATATSGADPVIMLTGPTPATQKVLDRAGLTVDDIDLFE MAB_0850|M.abscessus_ATCC_1997 KSQGLTPRARIVATATSGSEPLIMLTGPTPATKKVLDRAGLTVDDIDLFE TH_0166|M.thermoresistible__bu DRFNLTPRARIHHMSVRGADPVMMLTAPIPATQHALKRAGMSIDDIDAVE . *****: :. *::*::***.* **:::.*.***:::**** .* Mb0882|M.bovis_AF2122/97 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE Rv0859|M.tuberculosis_H37Rv LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE MLBr_02162|M.leprae_Br4923 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE MMAR_4677|M.marinum_M LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE MUL_0296|M.ulcerans_Agy99 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDE MAV_0980|M.avium_104 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDE Mflv_1691|M.gilvum_PYR-GCK LNEAFASVVLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDE MSMEG_5721|M.smegmatis_MC2_155 LNEAFASVVLKFQKDLGIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDE Mvan_5067|M.vanbaalenii_PYR-1 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDE MAB_0850|M.abscessus_ATCC_1997 LNEAFASVVLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDE TH_0166|M.thermoresistible__bu INEAFAPVVLAWLAELGADPARVNPNGGAIALGHPIGCTGARLMTSLLHH :*****.*** : :*. ::* ******:***:*.*** : :::.. Mb0882|M.bovis_AF2122/97 LERRNARRALITLCIGGGMGVATIIERV Rv0859|M.tuberculosis_H37Rv LERRNARRALITLCIGGGMGVATIIERV MLBr_02162|M.leprae_Br4923 LERCNARRALVTLCIGAGMGVATIIERV MMAR_4677|M.marinum_M LERRNARRALVTLCIGGGMGVATIIERV MUL_0296|M.ulcerans_Agy99 LERRNARRALVTLCIGGGMGAATIIERV MAV_0980|M.avium_104 LERRNARRALITLCIGGGMGVATIIERV Mflv_1691|M.gilvum_PYR-GCK LERRGARRALITLCVGGGMGVATIIERV MSMEG_5721|M.smegmatis_MC2_155 LERRGARRALITLCVGGGMGVATIIERV Mvan_5067|M.vanbaalenii_PYR-1 LERRGAKRALMTLCVGGGMGVATIIERV MAB_0850|M.abscessus_ATCC_1997 LERRGLKRALITLCVGGGMGVATIIERV TH_0166|M.thermoresistible__bu LERTGGRYGLQTMCEGGGQANVTIIERL *** . : .* *:* *.* . .*****: