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VSGSTAPLPVTSDPDTAGFWLAAQAGQVAVCVCANCGAVLHLPRSYCANCRSWTVEWKPVTAAARLVAWT VAEHQVHPAFPVPYTVVLVELDDSPGVRLAGHLPGRPALRAGMPMRADFQTRRDGATLVNWVPEPQSRTI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0902 | - | - | 100% (140) | hypothetical protein Mvan_0902 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 4e-09 | 31.00% (100) | hypothetical protein Mvan_4171 |
| M. vanbaalenii PYR-1 | Mvan_0530 | - | 5e-07 | 29.29% (99) | hypothetical protein Mvan_0530 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 3e-06 | 27.59% (145) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 3e-09 | 30.00% (100) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 3e-06 | 27.59% (145) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2052 | - | 5e-06 | 29.41% (119) | hypothetical protein MAB_2052 |
| M. marinum M | MMAR_4731 | - | 2e-11 | 29.93% (137) | 3-ketoacyl-CoA thiolase |
| M. avium 104 | MAV_2640 | - | 2e-12 | 33.87% (124) | hypothetical protein MAV_2640 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 2e-11 | 32.69% (104) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4505 | - | 1e-38 | 52.31% (130) | PUTATIVE protein of unknown function DUF35 |
| M. ulcerans Agy99 | MUL_0937 | - | 6e-10 | 37.84% (111) | hypothetical protein MUL_0937 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4731|M.marinum_M --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
Rv3542c|M.tuberculosis_H37Rv MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4731|M.marinum_M --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
Rv3542c|M.tuberculosis_H37Rv DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4731|M.marinum_M --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
Rv3542c|M.tuberculosis_H37Rv GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 ----------------------------MSGSTAPLPVTSDPDTAGFWLA
TH_4505|M.thermoresistible__bu -------------------------------MTRPVPYTDDHETGPFFAA
Mflv_2483|M.gilvum_PYR-GCK ----------------------------MSRLP---LPLLTFDNEFFWTS
MMAR_4731|M.marinum_M ----------------------------MSAAPGRPLPLITDENEFFWTS
MSMEG_4814|M.smegmatis_MC2_155 ----------------------------MSQIPGRPLPTVTALNEYFWTA
MAV_2640|M.avium_104 ----------------------------MVKVARADIPTIDAASAPYWEA
Mb3572c|M.bovis_AF2122/97 QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
Rv3542c|M.tuberculosis_H37Rv QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
MUL_0937|M.ulcerans_Agy99 -------------------------------MASRLAPAISPDTEFFWHG
MAB_2052|M.abscessus_ATCC_1997 --------------------MTAASSSLDGLHDPEALPPLTDVNRPYFAA
. :: .
Mvan_0902|M.vanbaalenii_PYR-1 AQAGQVAVCVCANCGAVLHLPRSYCANCRSWTVEWKPVTAAARLVAWTVA
TH_4505|M.thermoresistible__bu AREGALALCFCSRCDQVLHLPRAHCRFCGSWRTDWREVSGRGSVYSWTVV
Mflv_2483|M.gilvum_PYR-GCK GADGVLRIQECGDCKSLIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVN
MMAR_4731|M.marinum_M GADGKLRLQECAACASLIHPPAPVCRYCRSRDMGVRTVSGAATLTGFTVN
MSMEG_4814|M.smegmatis_MC2_155 GRDGVLRIQECRSCDALIHPPQPICRYCRSHDLGVRDVSGRATLAGFTVN
MAV_2640|M.avium_104 ARQGQLLIAECSACGKVHHYPRPFCPFCWSEDVAPVQASGTGTLYTYSTV
Mb3572c|M.bovis_AF2122/97 VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
Rv3542c|M.tuberculosis_H37Rv VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
MUL_0937|M.ulcerans_Agy99 LREHQLLIQRCAEFGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVMP
MAB_2052|M.abscessus_ATCC_1997 AARGVLVFQRCAN-GHPFLYPRLVCPVCHDGELAWETAAGTGEIVSFAPV
: . * . . : :
Mvan_0902|M.vanbaalenii_PYR-1 EHQVHPAFPV--PYTVVLVELDDSPGVRLAGHLPGRPALRAGMPMRADFQ
TH_4505|M.thermoresistible__bu ERQLHPAFPV--PYTLVLVSVHEYPEVRLLGHLPGRPALRAGMPMVA-IV
Mflv_2483|M.gilvum_PYR-GCK HRFSIPGLEA--PYVVAQVAIEEDPRVRLTTNIVDCDPDELELGRVVEVV
MMAR_4731|M.marinum_M HRFSLPGLPA--PYVIAQVAIAEDPRVRLTTNIVECDPDRLELGQTVEVV
MSMEG_4814|M.smegmatis_MC2_155 ERFGFPDMPP--PYVVAEVAIVEDPRVRLTTNIVDCDPQSLELGQPVEVS
MAV_2640|M.avium_104 YVNDLAPFKERVPYVAALVELTEGPRLMTTIEGADFDDLRVGMPVTAVFR
Mb3572c|M.bovis_AF2122/97 HAPKVPGRTV--PFVIALVELEEG--VRMLGELRGADPARVAIGMPVRAT
Rv3542c|M.tuberculosis_H37Rv HAPKVPGRTV--PFVIALVELEEG--VRMLGELRGADPARVAIGMPVRAT
MUL_0937|M.ulcerans_Agy99 HQPRFPFFDY--PYIVVLVELDEG--VRLVSNLCGIDPADVTVGMAVEVF
MAB_2052|M.abscessus_ATCC_1997 YRPPWDSFPRSEPYVVVLVRLDEGP--QLLASLEGVAPDEVAIGARVRAV
*: . * : : : .
Mvan_0902|M.vanbaalenii_PYR-1 TRR-DGATLVNWVPEPQSRTI-----------------------------
TH_4505|M.thermoresistible__bu ERV-DDTAVLNWAPQE----------------------------------
Mflv_2483|M.gilvum_PYR-GCK FEQNEDVWLPLFRPTAEPETAALPDDEIAPQEFPKFVRPMLTTEKFEDAA
MMAR_4731|M.marinum_M FERIEDVWLPLFRPRTDAQPRPLPVDEIAPQRFGEHVRPMLTTQKFEDKV
MSMEG_4814|M.smegmatis_MC2_155 FQHIDDVWLPVFTPSADTTPTPAPVEDIAPQDIGKFVRPMLTEDKFEDHS
MAV_2640|M.avium_104 PVDDTDPDSPYLTVFTPSEENP----------------------------
Mb3572c|M.bovis_AF2122/97 YIDF--PD--WSLYAWEPDE------------------------------
Rv3542c|M.tuberculosis_H37Rv YIDF--PD--WSLYAWEPDE------------------------------
MUL_0937|M.ulcerans_Agy99 YQDFDGPDGSFVLHQFRPVALDSEAVR-----------------------
MAB_2052|M.abscessus_ATCC_1997 FERVNEDLGLVRFRPAAS--------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK AITGIGASKMGRRLMVSPLSLTVEACEKAIADAGLTLADIDGLSTYPAMD
MMAR_4731|M.marinum_M ALTGIGMSTIGRRLMVAPLSLTVDACEAAVADAGLTFDDIDGLSTYPGGG
MSMEG_4814|M.smegmatis_MC2_155 AITGIGMSRIGRRLMVPPLSLTIEAAEQAVADAGLTFDDIDGLSTYPGLD
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK AMG-MGEGGCTVLEGALGIRPTWINGGMDTFGPGGSLIAAVMAVATGMAR
MMAR_4731|M.marinum_M NLGGFGEGGVTALEAALGIRPVWHNGGIETFGPGGSVIAAMLAVAGGLAR
MSMEG_4814|M.smegmatis_MC2_155 IAG-MGEGGVSVLEGALGLRPTWINGGMDTFGPGGSVIAAMMAISAGLAR
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK HVLCFRTLWEATFNQLMKEGKASPPGGARVNSWQAPFGATSAAHTLALNA
MMAR_4731|M.marinum_M HVLCFRTLWEATYNELMKRGKIAPPGG-RTTSWQYPFGATSAAHTLAINA
MSMEG_4814|M.smegmatis_MC2_155 HVLCFRTLWEATFGQLVKEGKMSPPMSARTNSWQQPYGATSAAHTLAQNA
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK QRHFHRYGTTKETLGWIALNQRANAALNPTAIYRDPMTMQDYLNARPITT
MMAR_4731|M.marinum_M QRHFHRYGTTKETLGWIALNQRANAELNPTAVYRSPMTMDDYLNARPITT
MSMEG_4814|M.smegmatis_MC2_155 GRHFHRYGTTRETLGWIALNQRANAALNPTAIYREPLTMEDYLSARTITT
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK PFGLYDCDVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIERTDWDQ
MMAR_4731|M.marinum_M PFGLFDCDVPCDAAIAVIVSAVDAARDLAKPPVLVEAVGTQIIERIDWDQ
MSMEG_4814|M.smegmatis_MC2_155 PFGLYDCDVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIERLDWDQ
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TTLTHEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALGFC
MMAR_4731|M.marinum_M STLTHEPQVLGQAAHVWTRTTLRPADVDVAELYDGFTMNCLSWIEALGFC
MSMEG_4814|M.smegmatis_MC2_155 TTLTHEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGLGFC
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4505|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK GIGESKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVSQLRG
MMAR_4731|M.marinum_M GIGEAKEFLDGGKNIARDGLIPLNTHGGQLSHGRTHGMGLLHEAVTQLRG
MSMEG_4814|M.smegmatis_MC2_155 GIGEAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQLRG
MAV_2640|M.avium_104 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0902|M.vanbaalenii_PYR-1 --------------------------------
TH_4505|M.thermoresistible__bu --------------------------------
Mflv_2483|M.gilvum_PYR-GCK EAGERQVADARVAVVSSGGLTPSGVMLLRTGA
MMAR_4731|M.marinum_M EADARQVAGARVGVVSSGGLTPSGVILLRADT
MSMEG_4814|M.smegmatis_MC2_155 EAGERQVEDARVAVASSGGLTPSGVLLLRRDD
MAV_2640|M.avium_104 --------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------