For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VKVARADIPTIDAASAPYWEAARQGQLLIAECSACGKVHHYPRPFCPFCWSEDVAPVQASGTGTLYTYST VYVNDLAPFKERVPYVAALVELTEGPRLMTTIEGADFDDLRVGMPVTAVFRPVDDTDPDSPYLTVFTPSE ENP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2640 | - | - | 100% (144) | hypothetical protein MAV_2640 |
| M. avium 104 | MAV_1938 | - | 1e-27 | 80.28% (71) | hypothetical protein MAV_1938 |
| M. avium 104 | MAV_5258 | - | 2e-15 | 34.96% (123) | hypothetical protein MAV_5258 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3572c | - | 3e-09 | 32.17% (115) | hypothetical protein Mb3572c |
| M. gilvum PYR-GCK | Mflv_2483 | - | 2e-13 | 29.79% (141) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3542c | - | 3e-09 | 32.17% (115) | hypothetical protein Rv3542c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2052 | - | 8e-17 | 36.44% (118) | hypothetical protein MAB_2052 |
| M. marinum M | MMAR_4248 | - | 8e-17 | 36.13% (119) | hypothetical protein MMAR_4248 |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 1e-17 | 37.23% (137) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_3574 | - | 2e-24 | 44.83% (116) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0937 | - | 4e-16 | 36.13% (119) | hypothetical protein MUL_0937 |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 8e-14 | 30.50% (141) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3572c|M.bovis_AF2122/97 MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
Rv3542c|M.tuberculosis_H37Rv MTGVSDIQEAVAQIKAAGPSKPRLARDPVNQPMINNWVEAIGDRNPIYVD
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
Rv3542c|M.tuberculosis_H37Rv DAAARAAGHPGIVAPPAMIQVWTMMGLGGVRPKDDPLGPIIKLFDDAGYI
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
Rv3542c|M.tuberculosis_H37Rv GVVATNCEQTYHRYLLPGEQVSISAELGDVVGPKQTALGEGWFINQHIVW
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4171|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4814|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
Rv3542c|M.tuberculosis_H37Rv QVGDEDVAEMNWRILKFKPAGSPSSVPDDLDPDAMMRPSSSRDTAFFWDG
MMAR_4248|M.marinum_M -------------------------------MASRLAPAISPDTEFFWHG
MUL_0937|M.ulcerans_Agy99 -------------------------------MASRLAPAISPDTEFFWHG
MAV_2640|M.avium_104 ----------------------------MVKVARADIPTIDAASAPYWEA
TH_3574|M.thermoresistible__bu ----------------------------MT-------PEIDTDSEAWWAA
Mflv_2483|M.gilvum_PYR-GCK ----------------------------MSRLP---LPLLTFDNEFFWTS
Mvan_4171|M.vanbaalenii_PYR-1 ----------------------------MSRLP---LPQLTFDNEFFWKS
MSMEG_4814|M.smegmatis_MC2_155 ----------------------------MSQIPGRPLPTVTALNEYFWTA
MAB_2052|M.abscessus_ATCC_1997 --------------------MTAASSSLDGLHDPEALPPLTDVNRPYFAA
* . :: .
Mb3572c|M.bovis_AF2122/97 VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
Rv3542c|M.tuberculosis_H37Rv VKAHELRIQRLAD-GSLRHPPVPAVWQDKSVPINYVVSSGRGTVFSFVVH
MMAR_4248|M.marinum_M LREHKLLIQRCAECGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVMP
MUL_0937|M.ulcerans_Agy99 LREHQLLIQRCAEFGELRHPPRPMCPKCRCLHWDTVESGGLGTVYSFVMP
MAV_2640|M.avium_104 ARQGQLLIAECSACGKVHHYPRPFCPFCWSEDVAPVQASGTGTLYTYSTV
TH_3574|M.thermoresistible__bu IQDGTLMVNHCRACRRNSLYPRPFCPHCWSESVELRPASGRGRLYTWSVV
Mflv_2483|M.gilvum_PYR-GCK GADGVLRIQECGDCKSLIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVN
Mvan_4171|M.vanbaalenii_PYR-1 GADGVLRIQECGDCKALIHPPQPVCRYCHSHNMGPREVSGRAVLSAFTVN
MSMEG_4814|M.smegmatis_MC2_155 GRDGVLRIQECRSCDALIHPPQPICRYCRSHDLGVRDVSGRATLAGFTVN
MAB_2052|M.abscessus_ATCC_1997 AARGVLVFQRCAN-GHPFLYPRLVCPVCHDGELAWETAAGTGEIVSFAPV
* . . * .* . : :
Mb3572c|M.bovis_AF2122/97 HAPKVP--GRTVPFVIALVELEEGV--RMLGELRGADPARVAIGMPVRAT
Rv3542c|M.tuberculosis_H37Rv HAPKVP--GRTVPFVIALVELEEGV--RMLGELRGADPARVAIGMPVRAT
MMAR_4248|M.marinum_M HQPRFP--FFDYPYIVVLVELDEGV--RLVSNLCGIDPADVTVGMAVEVF
MUL_0937|M.ulcerans_Agy99 HQPRFP--FFDYPYIVVLVELDEGV--RLVSNLCGIDPADVTVGMAVEVF
MAV_2640|M.avium_104 YVNDLAPFKERVPYVAALVELTEGP--RLMTTIEGADFDDLRVGMPVTAV
TH_3574|M.thermoresistible__bu HQ------SGRDPYVVAMVDLLEGP--RVMTAVEGCDIDALAADAELEVA
Mflv_2483|M.gilvum_PYR-GCK HRFSIP--GLEAPYVVAQVAIEEDPRVRLTTNIVDCDPDELELGRVVEVV
Mvan_4171|M.vanbaalenii_PYR-1 HRFSIP--GLQAPYVVAQVAIEEDPRVRLTTNIIDCDPDELELGRVVEVV
MSMEG_4814|M.smegmatis_MC2_155 ERFGFP--DMPPPYVVAEVAIVEDPRVRLTTNIVDCDPQSLELGQPVEVS
MAB_2052|M.abscessus_ATCC_1997 YRPPWDSFPRSEPYVVVLVRLDEGP--QLLASLEGVAPDEVAIGARVRAV
*:: . * : *. :: : . : . : .
Mb3572c|M.bovis_AF2122/97 YIDF---PD--WSLYAWEPDE-----------------------------
Rv3542c|M.tuberculosis_H37Rv YIDF---PD--WSLYAWEPDE-----------------------------
MMAR_4248|M.marinum_M YQDFD-GPDGSFVLHQFRPVALDSEAVR----------------------
MUL_0937|M.ulcerans_Agy99 YQDFD-GPDGSFVLHQFRPVALDSEAVR----------------------
MAV_2640|M.avium_104 FRPVDDTDPDSPYLTVFTPSEENP--------------------------
TH_3574|M.thermoresistible__bu YR----TDDGGFTVPVFRLCGG----------------------------
Mflv_2483|M.gilvum_PYR-GCK FE-----QNEDVWLPLFRPTAEPETAALPDDEIAPQEFPKFVRPMLTTEK
Mvan_4171|M.vanbaalenii_PYR-1 FE-----ENDDVWLPLFRPTAETETAPLPEDEIAPQDFGKFVRPMLTTEK
MSMEG_4814|M.smegmatis_MC2_155 FQ-----HIDDVWLPVFTPSADTTPTPAPVEDIAPQDIGKFVRPMLTEDK
MAB_2052|M.abscessus_ATCC_1997 FER----VNEDLGLVRFRPAAS----------------------------
: : :
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK FEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAIADAGLTLADIDGLST
Mvan_4171|M.vanbaalenii_PYR-1 FEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAIADAGLTLADIDGLST
MSMEG_4814|M.smegmatis_MC2_155 FEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAVADAGLTFDDIDGLST
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK YPAMDAMGMGEGGCTVLEGALGIRPTWINGGMDTFGPGGSLIAAVMAVAT
Mvan_4171|M.vanbaalenii_PYR-1 YPAMDAMGMGEGGVTALEGALGIRPTWINGGMDTFGPGGSVIAAVMAVAT
MSMEG_4814|M.smegmatis_MC2_155 YPGLDIAGMGEGGVSVLEGALGLRPTWINGGMDTFGPGGSVIAAMMAISA
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK GMARHVLCFRTLWEATFNQLMKEGKASPPGGARVNSWQAPFGATSAAHTL
Mvan_4171|M.vanbaalenii_PYR-1 GMARHVLCFRTLWEATFNQLMKEGRVSPPGGTRVNSWQAPFGATSAAHTL
MSMEG_4814|M.smegmatis_MC2_155 GLARHVLCFRTLWEATFGQLVKEGKMSPPMSARTNSWQQPYGATSAAHTL
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK ALNAQRHFHRYGTTKETLGWIALNQRANAALNPTAIYRDPMTMQDYLNAR
Mvan_4171|M.vanbaalenii_PYR-1 ALNAQRHFHRYGTTKETLGWIALNQRANAALNPTAIYRDPMTMDDYLNAR
MSMEG_4814|M.smegmatis_MC2_155 AQNAGRHFHRYGTTRETLGWIALNQRANAALNPTAIYREPLTMEDYLSAR
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK PITTPFGLYDCDVPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIERT
Mvan_4171|M.vanbaalenii_PYR-1 PITTPFGLYDCDVPCDGAVAVVVSAVDAAVDLPKPPVYFEAVGTQIIERT
MSMEG_4814|M.smegmatis_MC2_155 TITTPFGLYDCDVPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIERL
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK DWDQTTLTHEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEA
Mvan_4171|M.vanbaalenii_PYR-1 DWDQTTLTHEPQVLGQAAHLWTRTSLRPADVDVAELYDGFTFNCLSWLEA
MSMEG_4814|M.smegmatis_MC2_155 DWDQTTLTHEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEG
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 --------------------------------------------------
Rv3542c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4248|M.marinum_M --------------------------------------------------
MUL_0937|M.ulcerans_Agy99 --------------------------------------------------
MAV_2640|M.avium_104 --------------------------------------------------
TH_3574|M.thermoresistible__bu --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK LGFCGIGESKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVS
Mvan_4171|M.vanbaalenii_PYR-1 LGFCGIGEAKDFLDGGKAIARDGVIPLNTHGGQLSHGRTHGMGLIHEAVS
MSMEG_4814|M.smegmatis_MC2_155 LGFCGIGEAKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVT
MAB_2052|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3572c|M.bovis_AF2122/97 ------------------------------------
Rv3542c|M.tuberculosis_H37Rv ------------------------------------
MMAR_4248|M.marinum_M ------------------------------------
MUL_0937|M.ulcerans_Agy99 ------------------------------------
MAV_2640|M.avium_104 ------------------------------------
TH_3574|M.thermoresistible__bu ------------------------------------
Mflv_2483|M.gilvum_PYR-GCK QLRGEAGERQVADARVAVVSSGGLTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 QLRGEAGERQVDGARVAVVSSGGLTPSGALLLRTAT
MSMEG_4814|M.smegmatis_MC2_155 QLRGEAGERQVEDARVAVASSGGLTPSGVLLLRRDD
MAB_2052|M.abscessus_ATCC_1997 ------------------------------------