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DHDAYTQLLADLGAESEHLTGHLRALSFPQWGLATPAAGWGIQDQVTHLAYFDDATVMALQQPHEFRPFA DALMADGMDFPDRIAANHRILAPESMLDWYADSRAKLLDVLSKHEPRDRMPWFGPDMSAASAATARLMET WAHGQDIYDALGIEHPPSPGLRSIAHLGVATFAFSHRIHGVEVPSHAVHVALDAPDGGLWTWGPGDSADK VRGSAEDFVLVVTQRRHWTETDLVAEGSAAKGWLELAQAYAGAPSRRLPEVTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0343 | - | - | 100% (264) | hypothetical protein Mvan_0343 |
| M. vanbaalenii PYR-1 | Mvan_6059 | - | 7e-54 | 44.58% (249) | hypothetical protein Mvan_6059 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0037c | - | 1e-49 | 41.94% (248) | hypothetical protein Mb0037c |
| M. gilvum PYR-GCK | Mflv_4597 | - | 1e-62 | 47.39% (249) | wyosine base formation |
| M. tuberculosis H37Rv | Rv0036c | - | 1e-49 | 41.94% (248) | hypothetical protein Rv0036c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2059 | - | 2e-61 | 47.20% (250) | hypothetical protein MAB_2059 |
| M. marinum M | MMAR_0051 | - | 2e-51 | 42.11% (247) | hypothetical protein MMAR_0051 |
| M. avium 104 | MAV_0050 | - | 9e-52 | 43.95% (248) | hypothetical protein MAV_0050 |
| M. smegmatis MC2 155 | MSMEG_0336 | - | 9e-97 | 63.04% (257) | hypothetical protein MSMEG_0336 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0050 | - | 3e-51 | 41.70% (247) | hypothetical protein MUL_0050 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0037c|M.bovis_AF2122/97 -MADPGP-FVADLRAESDDLDALVAHLPADR--WADPTPAPGWTIAHQIG
Rv0036c|M.tuberculosis_H37Rv -MADPGP-FVADLRAESDDLDALVAHLPADR--WADPTPAPGWTIAHQIG
MAV_0050|M.avium_104 -MTGPAP-IVADLRAESDALDALVAPLPPGR--WADPTPAAGWTIAHQIG
MMAR_0051|M.marinum_M -MAGPGP-IVADLEAESDDLDALVAPLPPQR--WSELTPAPGWSIAHQIA
MUL_0050|M.ulcerans_Agy99 -MAGPGP-IVADLEAENDDLDALVAPLAPQR--WSELTPAPGWTIAHQIA
Mflv_4597|M.gilvum_PYR-GCK -MAVPMESLITDIGAETAELWSLIAELPEGQAGWDAPTPAAGWAVRDQIS
MAB_2059|M.abscessus_ATCC_1997 -MAVSMQSVITDIEAETAALRGLVAPLTEGPRGWDAPTPAVGWTIRDQIS
Mvan_0343|M.vanbaalenii_PYR-1 MDHDAYTQLLADLGAESEHLTGHLRALSFPQ--WGLATPAAGWGIQDQVT
MSMEG_0336|M.smegmatis_MC2_155 MALD-YGRLLDELRTESDLLTGHLQDLPFEE--WGRDTPAAGWSIQDQVS
.: :: :*. * . : *. * *** ** : .*:
Mb0037c|M.bovis_AF2122/97 HLLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELL
Rv0036c|M.tuberculosis_H37Rv HLLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELL
MAV_0050|M.avium_104 HLLWTDRVALIAVTDEPGFAEVLAGAAADPAGFVDKGAEELAAVAPAELL
MMAR_0051|M.marinum_M HLLWTDRVALTAVTDEAGFADVLTAAAANPAGFVDEGAEELAALPPAELL
MUL_0050|M.ulcerans_Agy99 HLLWTDRVALTAVTDEAGFADVLTAAAANPAGFVDEGAEELAAMPPAELL
Mflv_4597|M.gilvum_PYR-GCK HLAFFDDAAVRSATDPEGFTAEVLPMLADGRISPDTIAERYRPMPTAELL
MAB_2059|M.abscessus_ATCC_1997 HLAFFDDVAVRSATDPDGFSSDYLPMMADGAISPDVIAERYRQMPAADLL
Mvan_0343|M.vanbaalenii_PYR-1 HLAYFDDATVMALQQPHEFRPFADALMADGMDFPDRIAANHRILAPESML
MSMEG_0336|M.smegmatis_MC2_155 HLAFFDDAAKLALRQPDDFRAMADRLIAGGMDFPDRIAEQHRILAPDALL
** : * .: : : * *. * * . :.. :*
Mb0037c|M.bovis_AF2122/97 TDWRVTRGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDV
Rv0036c|M.tuberculosis_H37Rv TDWRVTRGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDV
MAV_0050|M.avium_104 ADWRATRDRLHRALLGVPAGRKLPWFGPPMSAASMATARLMETWAHGLDV
MMAR_0051|M.marinum_M SDWRLTRGRLHEALLNVADGRKLPWFGPPMSAASMATARLMETWAHGLDV
MUL_0050|M.ulcerans_Agy99 SDWRLTRGRLHEALLNVADGRKLPWFGPPMSAASMATARLMETWAHGLDV
Mflv_4597|M.gilvum_PYR-GCK SWFDGARRALVAAFAAIDPSMRVPWFGLPMSAASSLTARIMETWAHGQDI
MAB_2059|M.abscessus_ATCC_1997 AWFDTSRAALVAAFADIAPATRLPWFGPPMSAVSSLTARLMETWAHGQDV
Mvan_0343|M.vanbaalenii_PYR-1 DWYADSRAKLLDVLSKHEPRDRMPWFGPDMSAASAATARLMETWAHGQDI
MSMEG_0336|M.smegmatis_MC2_155 QWLLAARRDLLAALSEDDPKRRIPWFGPDMSVASCATARLMETWAHGRDI
:* * : ::.*** **..* ***:******* *:
Mb0037c|M.bovis_AF2122/97 ADALGVIRPATQRLRSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSG
Rv0036c|M.tuberculosis_H37Rv ADALGVIRPATQRLRSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSG
MAV_0050|M.avium_104 ADALGVTRPATDRLRSIAHLGVRTRDYAFAVNNLTPPAEPFLVELRGPRG
MMAR_0051|M.marinum_M ADALGVTRPATDRLRSIAHLGVRTRDYAYFVNNLAPPTEQFLVELRGPGG
MUL_0050|M.ulcerans_Agy99 ADALGVTRPATDRLRSIAHLGVRTRDYAYFVNNLAPPTEQFLVELRGPGG
Mflv_4597|M.gilvum_PYR-GCK ADALGVTRVPSARLRHVAHIGVGARAFSYMANGLEVPEEPVRVELTAPGG
MAB_2059|M.abscessus_ATCC_1997 VDALGATREATARLRHVAHIGVGARAFSYLANGLDLPADPVRVELTAPDG
Mvan_0343|M.vanbaalenii_PYR-1 YDALGIEHPPSPGLRSIAHLGVATFAFSHRIHGVEVPSHAVHVALDAPDG
MSMEG_0336|M.smegmatis_MC2_155 YETIGVAPPASPGLRSIAHLGVSTFAFSHRLNGQDVPSEPVAVQLHSPGG
:::* .: ** :**:** : ::. :. * . . * * .* *
Mb0037c|M.bovis_AF2122/97 DTWSWGPSDAAQRVTGSAEDFCFLVTQRRALSTLDVNAVGEDAQ-RWLTI
Rv0036c|M.tuberculosis_H37Rv DTWSWGPSDAAQRVTGSAEDFCFLVTQRRALSTLDVNAVGEDAQ-RWLTI
MAV_0050|M.avium_104 DTWSWGPPEAAQRVTGSAEDFCFLVTQRRPLSALDITADGADAQ-RWLEI
MMAR_0051|M.marinum_M DIWSWGPADAAQRVTGPAEDFCFLVTQRRPLSSLHLTATGEDAR-QWLQI
MUL_0050|M.ulcerans_Agy99 DLWSWGPADAAQRVTGPAEDFCFLVTQRRPLSSLHLTATGEDAR-QWLQI
Mflv_4597|M.gilvum_PYR-GCK TLWTWGPDGVPNRVTGTAHDFCLLVTQRRHRDDTALHVTGPLAD-QWLSI
MAB_2059|M.abscessus_ATCC_1997 SVWTWGPADAANRVSGPALDFCLLVTQRRHRDDTALVADGPLADHQWLAI
Mvan_0343|M.vanbaalenii_PYR-1 GLWTWGPGDSADKVRGSAEDFVLVVTQRRHWTETDLVAEGSAAK-GWLEL
MSMEG_0336|M.smegmatis_MC2_155 ETWTWGPQDAADRITGTAEDFVLVVTQRRHWTDTGLTVEGPVAT-GWMEV
*:*** .::: *.* ** ::***** : . * * *: :
Mb0037c|M.bovis_AF2122/97 AQAFAGPPGRGR----------
Rv0036c|M.tuberculosis_H37Rv AQAFAGPPGRGR----------
MAV_0050|M.avium_104 AQAFAGPPGPGR----------
MMAR_0051|M.marinum_M AQAFAGPPGEGR----------
MUL_0050|M.ulcerans_Agy99 AQAFAGPPGEGR----------
Mflv_4597|M.gilvum_PYR-GCK AQAFAGPPGGGRTAGQFDGGVS
MAB_2059|M.abscessus_ATCC_1997 AQAFAGPPGGGRVAGQFAGRQR
Mvan_0343|M.vanbaalenii_PYR-1 AQAYAGAPSRRLPEVTP-----
MSMEG_0336|M.smegmatis_MC2_155 AQAFAGAATKTEPKVQAR----
***:**..