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VAVPMESLITDIGAETAELWSLIAELPEGQAGWDAPTPAAGWAVRDQISHLAFFDDAAVRSATDPEGFTA EVLPMLADGRISPDTIAERYRPMPTAELLSWFDGARRALVAAFAAIDPSMRVPWFGLPMSAASSLTARIM ETWAHGQDIADALGVTRVPSARLRHVAHIGVGARAFSYMANGLEVPEEPVRVELTAPGGTLWTWGPDGVP NRVTGTAHDFCLLVTQRRHRDDTALHVTGPLADQWLSIAQAFAGPPGGGRTAGQFDGGVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4597 | - | - | 100% (270) | wyosine base formation |
| M. gilvum PYR-GCK | Mflv_0848 | - | 1e-61 | 48.22% (253) | wyosine base formation |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0037c | - | 7e-58 | 45.24% (252) | hypothetical protein Mb0037c |
| M. tuberculosis H37Rv | Rv0036c | - | 8e-58 | 45.24% (252) | hypothetical protein Rv0036c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2059 | - | 1e-116 | 74.63% (268) | hypothetical protein MAB_2059 |
| M. marinum M | MMAR_0051 | - | 8e-61 | 48.22% (253) | hypothetical protein MMAR_0051 |
| M. avium 104 | MAV_0050 | - | 3e-60 | 47.43% (253) | hypothetical protein MAV_0050 |
| M. smegmatis MC2 155 | MSMEG_0336 | - | 4e-67 | 49.21% (254) | hypothetical protein MSMEG_0336 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0050 | - | 2e-60 | 48.62% (253) | hypothetical protein MUL_0050 |
| M. vanbaalenii PYR-1 | Mvan_6059 | - | 8e-64 | 49.42% (257) | hypothetical protein Mvan_6059 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4597|M.gilvum_PYR-GCK MAVPMESLITDIGAETAELWSLIAELPEGQAGWDAPTPAAGWAVRDQISH
MAB_2059|M.abscessus_ATCC_1997 MAVSMQSVITDIEAETAALRGLVAPLTEGPRGWDAPTPAVGWTIRDQISH
Mb0037c|M.bovis_AF2122/97 MADPGP-FVADLRAESDDLDALVAHLPADR--WADPTPAPGWTIAHQIGH
Rv0036c|M.tuberculosis_H37Rv MADPGP-FVADLRAESDDLDALVAHLPADR--WADPTPAPGWTIAHQIGH
MAV_0050|M.avium_104 MTGPAP-IVADLRAESDALDALVAPLPPGR--WADPTPAAGWTIAHQIGH
MMAR_0051|M.marinum_M MAGPGP-IVADLEAESDDLDALVAPLPPQR--WSELTPAPGWSIAHQIAH
MUL_0050|M.ulcerans_Agy99 MAGPGP-IVADLEAENDDLDALVAPLAPQR--WSELTPAPGWTIAHQIAH
Mvan_6059|M.vanbaalenii_PYR-1 MADAAR-VIDELRAESDDLDALVAALPAAR--WTLPTPAPGWTIAHQIGH
MSMEG_0336|M.smegmatis_MC2_155 MALDYGRLLDELRTESDLLTGHLQDLPFEE--WGRDTPAAGWSIQDQVSH
*: .: :: :*. * . : *. * *** **:: .*:.*
Mflv_4597|M.gilvum_PYR-GCK LAFFDDAAVRSATDPEGFTAEVLPMLADGRISPDTIAERYRPMPTAELLS
MAB_2059|M.abscessus_ATCC_1997 LAFFDDVAVRSATDPDGFSSDYLPMMADGAISPDVIAERYRQMPAADLLA
Mb0037c|M.bovis_AF2122/97 LLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELLT
Rv0036c|M.tuberculosis_H37Rv LLWTDRVALTAVTDEAGFAELMTAAAANPAGFVDDAATELAAVSPAELLT
MAV_0050|M.avium_104 LLWTDRVALIAVTDEPGFAEVLAGAAADPAGFVDKGAEELAAVAPAELLA
MMAR_0051|M.marinum_M LLWTDRVALTAVTDEAGFADVLTAAAANPAGFVDEGAEELAALPPAELLS
MUL_0050|M.ulcerans_Agy99 LLWTDRVALTAVTDEAGFADVLTAAAANPAGFVDEGAEELAAMPPAELLS
Mvan_6059|M.vanbaalenii_PYR-1 LMWTDRVALLSVTDEAGFAAVLAQASENPGGFVDAAAEELALTSPGELLA
MSMEG_0336|M.smegmatis_MC2_155 LAFFDDAAKLALRQPDDFRAMADRLIAGGMDFPDRIAEQHRILAPDALLQ
* : * .* : : .* . * * . .. **
Mflv_4597|M.gilvum_PYR-GCK WFDGARRALVAAFAAIDPSMRVPWFGLPMSAASSLTARIMETWAHGQDIA
MAB_2059|M.abscessus_ATCC_1997 WFDTSRAALVAAFADIAPATRLPWFGPPMSAVSSLTARLMETWAHGQDVV
Mb0037c|M.bovis_AF2122/97 DWRVTRGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDVA
Rv0036c|M.tuberculosis_H37Rv DWRVTRGRLHEELLAVPDGRKLAWFGPPMSAASMATARLMETWAHGLDVA
MAV_0050|M.avium_104 DWRATRDRLHRALLGVPAGRKLPWFGPPMSAASMATARLMETWAHGLDVA
MMAR_0051|M.marinum_M DWRLTRGRLHEALLNVADGRKLPWFGPPMSAASMATARLMETWAHGLDVA
MUL_0050|M.ulcerans_Agy99 DWRLTRGRLHEALLNVADGRKLPWFGPPMSAASMATARLMETWAHGLDVA
Mvan_6059|M.vanbaalenii_PYR-1 DWRATRAALHDALSTVADGRKLPWFGPPMSAASMATARLMETWAHGLDVA
MSMEG_0336|M.smegmatis_MC2_155 WLLAARRDLLAALSEDDPKRRIPWFGPDMSVASCATARLMETWAHGRDIY
:* * : ::.*** **..* ***:******* *:
Mflv_4597|M.gilvum_PYR-GCK DALGVTRVPSARLRHVAHIGVGARAFSYMANGLEVPEEPVRVELTAPGGT
MAB_2059|M.abscessus_ATCC_1997 DALGATREATARLRHVAHIGVGARAFSYLANGLDLPADPVRVELTAPDGS
Mb0037c|M.bovis_AF2122/97 DALGVIRPATQRLRSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSGD
Rv0036c|M.tuberculosis_H37Rv DALGVIRPATQRLRSIAHLGVRTRDYAFIVNNLTPPAEPFLVELRGPSGD
MAV_0050|M.avium_104 DALGVTRPATDRLRSIAHLGVRTRDYAFAVNNLTPPAEPFLVELRGPRGD
MMAR_0051|M.marinum_M DALGVTRPATDRLRSIAHLGVRTRDYAYFVNNLAPPTEQFLVELRGPGGD
MUL_0050|M.ulcerans_Agy99 DALGVTRPATDRLRSIAHLGVRTRDYAYFVNNLAPPTEQFLVELRGPGGD
Mvan_6059|M.vanbaalenii_PYR-1 DALGVTRAPTARLRSIAHIGVRTRDFAFTVHGLTPPPEPFHVKLSAPHGA
MSMEG_0336|M.smegmatis_MC2_155 ETIGVAPPASPGLRSIAHLGVSTFAFSHRLNGQDVPSEPVAVQLHSPGGE
:::*. .: ** :**:** : ::. :. * : . *:* .* *
Mflv_4597|M.gilvum_PYR-GCK LWTWGPDGVPNRVTGTAHDFCLLVTQRRHRDDTALHVTGPLAD-QWLSIA
MAB_2059|M.abscessus_ATCC_1997 VWTWGPADAANRVSGPALDFCLLVTQRRHRDDTALVADGPLADHQWLAIA
Mb0037c|M.bovis_AF2122/97 TWSWGPSDAAQRVTGSAEDFCFLVTQRRALSTLDVNAVGEDAQ-RWLTIA
Rv0036c|M.tuberculosis_H37Rv TWSWGPSDAAQRVTGSAEDFCFLVTQRRALSTLDVNAVGEDAQ-RWLTIA
MAV_0050|M.avium_104 TWSWGPPEAAQRVTGSAEDFCFLVTQRRPLSALDITADGADAQ-RWLEIA
MMAR_0051|M.marinum_M IWSWGPADAAQRVTGPAEDFCFLVTQRRPLSSLHLTATGEDAR-QWLQIA
MUL_0050|M.ulcerans_Agy99 LWSWGPADAAQRVTGPAEDFCFLVTQRRPLSSLHLTATGEDAR-QWLQIA
Mvan_6059|M.vanbaalenii_PYR-1 QWTWGPEDAAQRVTGSAEHFCMLATQRRPRAALDVVAVGPDAE-KWLTIA
MSMEG_0336|M.smegmatis_MC2_155 TWTWGPQDAADRITGTAEDFVLVVTQRRHWTDTGLTVEGPVAT-GWMEVA
*:*** ..:*::*.* .* ::.**** : . * * *: :*
Mflv_4597|M.gilvum_PYR-GCK QAFAGPPGGGRTAGQFDGGVS
MAB_2059|M.abscessus_ATCC_1997 QAFAGPPGGGRVAGQFAGRQR
Mb0037c|M.bovis_AF2122/97 QAFAGPPGRGR----------
Rv0036c|M.tuberculosis_H37Rv QAFAGPPGRGR----------
MAV_0050|M.avium_104 QAFAGPPGPGR----------
MMAR_0051|M.marinum_M QAFAGPPGEGR----------
MUL_0050|M.ulcerans_Agy99 QAFAGPPGEGR----------
Mvan_6059|M.vanbaalenii_PYR-1 QAFAGPPGPGRG---------
MSMEG_0336|M.smegmatis_MC2_155 QAFAGAATKTEPKVQAR----
*****.. .