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MKLKALLVVLVSAVLALAGCSVDNGGQHGDDSGKPTIRIGYQTFPSGDLIVKNNKWLEEALPDYNIKWTK FDSGADVNTAFVAGELDFGALGSSPVARGLSEPLNIPYKVAFVLDVAGDNEALVVRNGAGVDTIAQLKGR RIGTPFASTAHYSLLAALDQNGLSANDVQLIDLQPQAILAAWERGDIDAAYTWLPTLDELRKTGRDLITS RQLADAGKPTLDLATVSDEFASAHPEAVDVWRQQQGRALDLIREDPQAAAEAIAAEIGLTPQDVAGQLKQ MVFLTPQDISSTEWLGTEGNPGNLAVNLESASQFLADQSQIPAAAPLKTFQDAVYTKGLPGALNE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0122 | - | - | 100% (345) | substrate-binding region of ABC-type glycine betaine transport system |
| M. vanbaalenii PYR-1 | Mvan_3411 | - | 1e-15 | 30.92% (207) | aliphatic sulfonate ABC transporter periplasmic ligand-binding |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0723 | - | 1e-161 | 79.71% (345) | substrate-binding region of ABC-type glycine betaine transport |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01629 | smc | 2e-05 | 27.13% (247) | putative cell division protein |
| M. abscessus ATCC 19977 | MAB_2177 | - | 1e-143 | 71.43% (343) | ABC transporter periplasmic protein |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3400 | - | 3e-20 | 27.68% (289) | ABC transporter substrate-binding protein |
| M. smegmatis MC2 155 | MSMEG_0114 | - | 1e-156 | 77.10% (345) | extracellular solute-binding protein, family protein 3 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 MYLKSLTLKGFKSFASPTTLRFEPGITAVVGPNGSGKSNVVDALAWVMGE
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 QGAKTLRGSKMEDVIFAGTLSRAPLGRAEVTLIIDNSDNVLPIEYSEVSI
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 TRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVGQGKLDQIL
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 QSRPEDRRTFIEEAAGILKYRRRKEKALRKLDAMSANLARLTDLTTELRR
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 QLKPLSRQAEVARRAATIQADLRDARLRLAADDLVSRQGQRDAIVEAETM
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 MRRDHDEAAARLAVASEELAAHEAALTELSGRAESVQQIWFGLSTLVERV
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 SATIRIAGERAYHLDVDPATPSDTDPDVLEAEAQQMEVAEQQLLAELAVA
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 RTQLEAARAELADRERHAVEADKAHLEAVRAEADRREGLALLAGQVETMR
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 ARIESIDDSVARLSERIEEVTARTQQILAEFETVQGRVGELDQSEVHLDE
Mvan_0122|M.vanbaalenii_PYR-1 ----------------------------------MKLKALLVVLVSAVLA
Mflv_0723|M.gilvum_PYR-GCK ----------------------------------MRFKALLVALVAGMLA
MSMEG_0114|M.smegmatis_MC2_155 ----------------------------------MKLKSLLVATAASALA
MAB_2177|M.abscessus_ATCC_1997 ----------------------------------MRLNYLAAALAVAMTM
MAV_3400|M.avium_104 ---------------------------------MRRHAALLASVLIAVAA
MLBr_01629|M.leprae_Br4923 QHERAVAALRFANERVAELQSAERDAERQVVSLRARIDALTMGLERKDGA
: *
Mvan_0122|M.vanbaalenii_PYR-1 L-AGCSVDNGGQHGDDSGKPTIRIGYQTFPS-------------------
Mflv_0723|M.gilvum_PYR-GCK L-AGCSVGSGGQSGNDPEKPTIRIGYQTFPS-------------------
MSMEG_0114|M.smegmatis_MC2_155 L-AGCAVDNSEQ---DAEKPTIRVGYQTFPS-------------------
MAB_2177|M.abscessus_ATCC_1997 L-SGCAIDHSGLQ---NGKPTIRIGYQNFPS-------------------
MAV_3400|M.avium_104 LGTGCSLESLSQS---AGVVNVVVGYQSKTINTV----------------
MLBr_01629|M.leprae_Br4923 AWLARNYSDTGLLGSIAKLVKVRPGYEAALAAVLGPAADALAVDSLGAAR
. .: **:
Mvan_0122|M.vanbaalenii_PYR-1 ---------------------------------------GDLIVKNNKWL
Mflv_0723|M.gilvum_PYR-GCK ---------------------------------------GDLIVKNNKWL
MSMEG_0114|M.smegmatis_MC2_155 ---------------------------------------GDLIVKNNGWL
MAB_2177|M.abscessus_ATCC_1997 ---------------------------------------GDLVVKQNRWL
MAV_3400|M.avium_104 --------------------------------------TAGTLLRAQGYL
MLBr_01629|M.leprae_Br4923 SALTALKEADAGRATLVLADWLADAGPACVTGLPDGAQRALDLIEAPPWL
. ::. :*
Mvan_0122|M.vanbaalenii_PYR-1 EEALPDYN---------------------------------IKWTKFDSG
Mflv_0723|M.gilvum_PYR-GCK EEALPDHN---------------------------------IKWVKFDSG
MSMEG_0114|M.smegmatis_MC2_155 EEALPDYN---------------------------------IKWTKFDSG
MAB_2177|M.abscessus_ATCC_1997 ETALPDYN---------------------------------IKWTRFDSG
MAV_3400|M.avium_104 ERRLADITT-------------------------RTGTKYAVRWQDYDTG
MLBr_01629|M.leprae_Br4923 QGALIAMLYGVVVVNYLAEALGVVDICPQLRVVTVDGDLVGAGWVSGGSG
: * * .:*
Mvan_0122|M.vanbaalenii_PYR-1 ADVNTAFVAGELDFGALGSSPVARGLSEPLNIPYKVAFVLDVAGDN----
Mflv_0723|M.gilvum_PYR-GCK ADVNTAFVADELDFGALGSSPVARGLSEPLNIPYQVAFILDVAGDN----
MSMEG_0114|M.smegmatis_MC2_155 ADVNTAFVAGELDFGALGSSPVARGLSAPLNIPYKVAFVLDVAGDN----
MAB_2177|M.abscessus_ATCC_1997 ADINTAFIARELDFGALGSSPFARGLSAPLNIPYRVAFVLDVAGDN----
MAV_3400|M.avium_104 APITAQMLAEKIDIGSMGDYPMLINGSKTQANPLARTEMVSITGYNPKGA
MLBr_01629|M.leprae_Br4923 RRLSTLEVTSEIDK-AGAELAAAEAHMAQLNAALSGALSEQVAHSDATEQ
:.: :: ::* : .. . . : .:: :
Mvan_0122|M.vanbaalenii_PYR-1 -EALVVRNGAGVDTIAQLKGRRIGTPFASTAHYSLLAALDQ---------
Mflv_0723|M.gilvum_PYR-GCK -EALVARNAAGITTIADLRDKRVATPFASTAHYSLLAALDQ---------
MSMEG_0114|M.smegmatis_MC2_155 -EALVARDGSGVNSIADLRGKRVATPFASTAHYSLLAALAQ---------
MAB_2177|M.abscessus_ATCC_1997 -EALVASNRSGVSTIAGLKGKRVGTPFASTAHYSLLSALAQ---------
MAV_3400|M.avium_104 LNMVVVSPESRAKDLADLAGAKVSASVGSAGHGTLVRALSR---------
MLBr_01629|M.leprae_Br4923 ALVALNESDTAILSMYDQLGRLGQEVRAAEAEWESLLAQREELEARRVSI
: : : . .: .. : * .
Mvan_0122|M.vanbaalenii_PYR-1 -NGLSANDVQLIDLQPQAILAAWERGDIDAAYTWLPTLDELR--------
Mflv_0723|M.gilvum_PYR-GCK -NGLSPNDVQLIDLQPQAILAAWERGDIDAAYTWLPTLNELR--------
MSMEG_0114|M.smegmatis_MC2_155 -NGLSPNDVQLIDLQPQAILAAWERGDIAAAYSWLPTLDDLR--------
MAB_2177|M.abscessus_ATCC_1997 -NGLSASDVRLVDLQPQAALAAFDRGDVDAVYTWLPTVDQVR--------
MAV_3400|M.avium_104 -AGVN--GVEVLNQQPQVGASALESGQVQALSQFVAWPGLLV--------
MLBr_01629|M.leprae_Br4923 LEEVVELETRLHNVEQIQHVHALDENSAAARQLIVAAAEEARGVEVEALL
: ..: : : * : .. * :.
Mvan_0122|M.vanbaalenii_PYR-1 -----------KTGRDLITSRQLADAGKPTLD------------------
Mflv_0723|M.gilvum_PYR-GCK -----------KTGKDLITSRQLAAEGKPTLD------------------
MSMEG_0114|M.smegmatis_MC2_155 -----------KTGKDLITSRELAADGKPTLD------------------
MAB_2177|M.abscessus_ATCC_1997 -----------KNGRDLITSRQLAADGRPTLD------------------
MAV_3400|M.avium_104 -----------FQGKAKLLYDGAELN-LPTLH------------------
MLBr_01629|M.leprae_Br4923 AVRTAEERVNAVCGRANSLRRAAAAEREVRLRDQQAHAARIRAAAVAAAV
*: *
Mvan_0122|M.vanbaalenii_PYR-1 ---------LATVSDEFASAHPEAVDVWRQQQGRALDLIREDPQAAAEAI
Mflv_0723|M.gilvum_PYR-GCK ---------LAVVSSEFAKSHPEVVDTWRKQQARALDVIADDPAAAAKAI
MSMEG_0114|M.smegmatis_MC2_155 ---------LGVVSDKFATEHPDVVDTWREQEARALDVIKDDPDAAAKAI
MAB_2177|M.abscessus_ATCC_1997 ---------LAVVANAFADAHPEIVDAWRRQQARALRLIHDDPSAAAKAI
MAV_3400|M.avium_104 ---------GVVVRRSYAAAHPEVLAAFLQAQLDATDFLNTHPLQAARIV
MLBr_01629|M.leprae_Br4923 TDCGQLLASRLTQAVDLAARHRDALATERQQRSVAIAAVRYEVNTLRVRL
. * * : : . . . * : . :
Mvan_0122|M.vanbaalenii_PYR-1 AAEIG---------LTPQ-------------------DVAGQLKQMVFLT
Mflv_0723|M.gilvum_PYR-GCK AAEVG---------LTPE-------------------DIEGQLTQTVFLT
MSMEG_0114|M.smegmatis_MC2_155 AAEIG---------LSPE-------------------DVAGQLKQGVYLT
MAB_2177|M.abscessus_ATCC_1997 AAENG---------LTPQ-------------------EVADQLKQGIYLT
MAV_3400|M.avium_104 ADASG---------LPPEVVYLYNGPGGTSFDTTLKPSLTEALKSDVPYL
MLBr_01629|M.leprae_Br4923 ATLTDSLHRDEVANVQAALRIEQLEQLVLEQFGIAPVDLIAEYGPQVALL
* . : . .: :
Mvan_0122|M.vanbaalenii_PYR-1 P-----QDISSTEWLGTE--------------------GNPGNLAVNLES
Mflv_0723|M.gilvum_PYR-GCK P-----EQVASAEWLGDD--------------------GKPGNLAANLQS
MSMEG_0114|M.smegmatis_MC2_155 P-----AEVASEQWLGSD--------------------GKPGNIAANLQS
MAB_2177|M.abscessus_ATCC_1997 P-----AEVGSAKWLGEQ--------------------GKPGHIAVDLQS
MAV_3400|M.avium_104 KSIGDFADLDVDKFVVDEPLRAVFTARGLDYQAARARTTNPSTLRGDPAL
MLBr_01629|M.leprae_Br4923 PTELEMAEFQQARERGEQ------------VTSPAPMPYDRATQERRAKR
:. . : . .
Mvan_0122|M.vanbaalenii_PYR-1 ASQFLAD-----QSQIPAAAPLKTFQDAV---------------------
Mflv_0723|M.gilvum_PYR-GCK ASEFLAE-----QKQIPAAAPLNTFQDGL---------------------
MSMEG_0114|M.smegmatis_MC2_155 ASEFLAE-----QKQIPEAAPLGTFEDAI---------------------
MAB_2177|M.abscessus_ATCC_1997 ASQFLAD-----QKQIPAAAPLATFENAV---------------------
MAV_3400|M.avium_104 AGELWLDGADTTQTTADPASLLRAVRDALGRGARVRAAYVPDTEFGTRWF
MLBr_01629|M.leprae_Br4923 AERELAELGRVNPLALEEFAALEERYNFLSTQLEDVKG--ARKDLLDVVA
* . : : * : :
Mvan_0122|M.vanbaalenii_PYR-1 ------------------------YTKGLPGALNE---------------
Mflv_0723|M.gilvum_PYR-GCK ------------------------YTRGLPGVLTE---------------
MSMEG_0114|M.smegmatis_MC2_155 ------------------------YTKGLPGAISK---------------
MAB_2177|M.abscessus_ATCC_1997 ------------------------YTKGLPDAIGR---------------
MAV_3400|M.avium_104 ADKAFWVKDGQNYLPFGTAAGAGRYLAAHPGSIAVNYQQALGGSV-----
MLBr_01629|M.leprae_Br4923 EVDARILQVFSDAFVDVEREFRGVFTSLFPGGEGRLRLTDPDDMLTTGIE
: *.
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 VEARPSGKKVSRLSLLSGGEKSLIAVAMLVAIFKARPSPFYIMDEVEAAL
Mvan_0122|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0723|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0114|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2177|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3400|M.avium_104 --------------------------------------------------
MLBr_01629|M.leprae_Br4923 DDVNLCRLIGVFEQLRGQSQLIIITHQKPTMEVADTLYGVTMQGDGITAV
Mvan_0122|M.vanbaalenii_PYR-1 ------------------
Mflv_0723|M.gilvum_PYR-GCK ------------------
MSMEG_0114|M.smegmatis_MC2_155 ------------------
MAB_2177|M.abscessus_ATCC_1997 ------------------
MAV_3400|M.avium_104 ------------------
MLBr_01629|M.leprae_Br4923 ISQRMRGQQVESLVTSSS