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PDPRRSEMSQDDKAAQTRKSFAESVKGKAKELAGAVTGNDSLTAEGQLEQAEAKERREASRKEAEADAEA AQAQAQAREARLEGAQERAAAEVRAAGVETQVSADQAAARQSVEEAGRRDVARAQTQAEAKVAQESARAQ AEQREEIVEAAEEYQEAAADYQEATSEAARAEAQAERLRQRANDSTPT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5236 | - | - | 100% (189) | CsbD family protein |
| M. gilvum PYR-GCK | Mflv_3881 | - | 2e-12 | 56.25% (64) | CsbD family protein |
| M. gilvum PYR-GCK | Mflv_2022 | - | 8e-12 | 45.57% (79) | CsbD family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2169c | wag31 | 7e-06 | 29.79% (94) | hypothetical protein Mb2169c |
| M. tuberculosis H37Rv | Rv2145c | wag31 | 7e-06 | 29.79% (94) | hypothetical protein Rv2145c |
| M. leprae Br4923 | MLBr_00922 | ag84 | 4e-05 | 29.29% (99) | immunogenic protein, antigen 84 |
| M. abscessus ATCC 19977 | MAB_3217 | - | 4e-11 | 48.05% (77) | hypothetical protein MAB_3217 |
| M. marinum M | MMAR_2416 | lgt | 4e-10 | 33.33% (162) | prolipoprotein diacylglyceryl transferases Lgt |
| M. avium 104 | MAV_3734 | - | 5e-13 | 48.15% (81) | hypothetical protein MAV_3734 |
| M. smegmatis MC2 155 | MSMEG_1950 | - | 7e-45 | 52.51% (179) | hypothetical protein MSMEG_1950 |
| M. thermoresistible (build 8) | TH_4168 | - | 3e-11 | 48.53% (68) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2228 | - | 5e-09 | 48.44% (64) | hypothetical protein MUL_2228 |
| M. vanbaalenii PYR-1 | Mvan_1034 | - | 1e-60 | 69.77% (172) | CsbD-like protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARG
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M GERGVIYDIALWMVPFGLIGGRLYHLSTDWQTYFGEGGAGLGAALRIWDG
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M GLGIWGAVTLGTVGAWIGCRRRGIPLPAFLDAVAPGVVMGQAIGRLGNYF
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M NQELYGRETTVPWGLEIFYRRDPSGFVDVHSLDGVSTGQVAVVVQPTFLY
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M ELIWNLLVFAALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLRDDTAT
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M HIAGIRINSFTSTFVFIGAVVYIILAPKGREDPASVRGTAAAAEEVPEPE
Mflv_5236|M.gilvum_PYR-GCK ------------------------------------------------MP
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 ---------------------------------------MPLTPADVHNV
Rv2145c|M.tuberculosis_H37Rv ---------------------------------------MPLTPADVHNV
MLBr_00922|M.leprae_Br4923 ---------------------------------------MPLTPADVHNV
MMAR_2416|M.marinum_M PAGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPETVGSAVAGDESTAD
Mflv_5236|M.gilvum_PYR-GCK DPRRSEMSQ---DDKAAQTRKSFAE-----------SVKGKAKELAGAVT
Mvan_1034|M.vanbaalenii_PYR-1 ------MS----DDKAAQTRKSFVE-----------ALKGKAKEVAGAIT
MSMEG_1950|M.smegmatis_MC2_155 ------MTQ---HSKSDQARKSFID-----------SVKGTAKEVVGAVT
MAV_3734|M.avium_104 ------MAEEN-KSGPAEAVKGVVE-----------DVKGKAKEAVGAVA
MUL_2228|M.ulcerans_Agy99 ------MAD---KSGPQEAVEGVVE-----------GAKGKAKEVFEAVT
TH_4168|M.thermoresistible__bu ------MSDNR-NSGPQEAIRGVVE-----------DAKGKAKEVIGTVT
MAB_3217|M.abscessus_ATCC_1997 ------MSDDNKDSGFEAGIKGVVE-----------DVKGKVKEAAGKLT
Mb2169c|M.bovis_AF2122/97 AFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLRQRINELDQELA
Rv2145c|M.tuberculosis_H37Rv AFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLRQRINELDQELA
MLBr_00922|M.leprae_Br4923 AFSKPPIGKRGYNEDEVDAFLDLVENELTQLIEENSDLRQRIEELDHELA
MMAR_2416|M.marinum_M TEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAEEAEP
: . : . :* .
Mflv_5236|M.gilvum_PYR-GCK G-----------------------------------------NDSLTAEG
Mvan_1034|M.vanbaalenii_PYR-1 G-----------------------------------------NDSLTAEG
MSMEG_1950|M.smegmatis_MC2_155 G-----------------------------------------NDSLTAEG
MAV_3734|M.avium_104 G-----------------------------------------RDDLTREG
MUL_2228|M.ulcerans_Agy99 G-----------------------------------------RDDVKREG
TH_4168|M.thermoresistible__bu G-----------------------------------------REDLTREG
MAB_3217|M.abscessus_ATCC_1997 G-----------------------------------------DESLEREG
Mb2169c|M.bovis_AF2122/97 AGGGAGVTP------QATQAIPAYEPE--PGKPAPAAVSAGMNEEQALKA
Rv2145c|M.tuberculosis_H37Rv AGGGAGVTP------QATQAIPAYEPE--PGKPAPAAVSAGMNEEQALKA
MLBr_00922|M.leprae_Br4923 AGGGTGAGPV--IAVQPTQALSTFEPELVSAKQAPVAAVAETAEELAMKA
MMAR_2416|M.marinum_M GEVEVAEAVEGEVEAAAEAEEAEEAEEAEEAEEAEEAEPGEIEVAEAVEG
. :.
Mflv_5236|M.gilvum_PYR-GCK QLEQAEAKERREASRKEAEADAEAAQAQAQAREARLEGAQERAAAEVRAA
Mvan_1034|M.vanbaalenii_PYR-1 QLEQAEAKERRAASRNEAEADAEAAQAREKAGEAELRGAQQRARAEVQAA
MSMEG_1950|M.smegmatis_MC2_155 QLEKTQAKERREAGRAAAVADAEARQARAEEAQAQADGAQKRAAVAAEAA
MAV_3734|M.avium_104 QAQQDKAEAQRDAAK--KEAEAEAARGGAEAAEERQRANQ----------
MUL_2228|M.ulcerans_Agy99 QAQQDKADAQRDAAK--KEAEAEAARRGADVAEERQKANQ----------
TH_4168|M.thermoresistible__bu QAQQDKADAQRDAAK--KEAEAERARANAKVDEQRQKAAQRPD-------
MAB_3217|M.abscessus_ATCC_1997 QAQQDKAEAQREVAT--KEAEAEKARAEAAVHEAREDAEK----------
Mb2169c|M.bovis_AF2122/97 ARVLSLAQDTADRLTNTAKAESDKMLADARANAEQILGEARHTADATVAE
Rv2145c|M.tuberculosis_H37Rv ARVLSLAQDTADRLTNTAKAESDKMLADARANAEQILGEARHTADATVAE
MLBr_00922|M.leprae_Br4923 TRVLSLAQDTADQLTSTAKVESDKMLADARVNADQILGEARLTAEATVAE
MMAR_2416|M.marinum_M EVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIEAAEAVEGEVEVAAEAE
:: .
Mflv_5236|M.gilvum_PYR-GCK GVETQVSADQAAARQSVEEAGRRDVARAQTQAEAKVAQ-ESARAQAEQRE
Mvan_1034|M.vanbaalenii_PYR-1 TAESAVRSEQAARRQMAEESGRRDVAGAQSAFEADVQR-EAQRATAERRG
MSMEG_1950|M.smegmatis_MC2_155 VVENDVRAQQDAQKREAEAAARRDAERQKTQADIDAQR-EVQLADAAERS
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 ARQRADAMLADAQSRSEAQLRQAQEKADALQADAERKHSEIMGTINQQRA
Rv2145c|M.tuberculosis_H37Rv ARQRADAMLADAQSRSEAQLRQAQEKADALQADAERKHSEIMGTINQQRA
MLBr_00922|M.leprae_Br4923 AQQRADAMLADAQTRSEVQSRQAQEKADALQAEAERKHSEIMGAISQQRT
MMAR_2416|M.marinum_M EAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGGQTGVDDAGEADAEPDD
Mflv_5236|M.gilvum_PYR-GCK EIVEAAEEYQEAAADYQEATSEAARAEAQAERLRQRAN--DSTPT-----
Mvan_1034|M.vanbaalenii_PYR-1 RVADAAEEYHEAAADYQQKTAEAERAEADADRLRRQAAAADDHPKLP---
MSMEG_1950|M.smegmatis_MC2_155 DVAVARQEAAEAAADHQDAVKESADVRARADRMRQEADKLTEEADLPGDE
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 VLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSNADAGGFD
Rv2145c|M.tuberculosis_H37Rv VLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSNADAGGFD
MLBr_00922|M.leprae_Br4923 VLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSNADAGGFD
MMAR_2416|M.marinum_M DSTAAEPEVVVEQADIEEIEPQEPEAEAVAAAEATDADEGDGEPAEPASD
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 K-------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 QFNRGKN-------------------------------------------
Rv2145c|M.tuberculosis_H37Rv QFNRGKN-------------------------------------------
MLBr_00922|M.leprae_Br4923 QFNRGNN-------------------------------------------
MMAR_2416|M.marinum_M DLDAVAAEDADVDVDATATEAEESGDESPEPAADSEEPEADESAPEDSAE
Mflv_5236|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1950|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3734|M.avium_104 --------------------------------------------------
MUL_2228|M.ulcerans_Agy99 --------------------------------------------------
TH_4168|M.thermoresistible__bu --------------------------------------------------
MAB_3217|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2169c|M.bovis_AF2122/97 --------------------------------------------------
Rv2145c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00922|M.leprae_Br4923 --------------------------------------------------
MMAR_2416|M.marinum_M DTSSGESDTQSELEQSQTIEQGSDQTSAGDGEGPPPSAAVDGDTGPTRQG
Mflv_5236|M.gilvum_PYR-GCK --------------
Mvan_1034|M.vanbaalenii_PYR-1 --------------
MSMEG_1950|M.smegmatis_MC2_155 --------------
MAV_3734|M.avium_104 --------------
MUL_2228|M.ulcerans_Agy99 --------------
TH_4168|M.thermoresistible__bu --------------
MAB_3217|M.abscessus_ATCC_1997 --------------
Mb2169c|M.bovis_AF2122/97 --------------
Rv2145c|M.tuberculosis_H37Rv --------------
MLBr_00922|M.leprae_Br4923 --------------
MMAR_2416|M.marinum_M WRGRLRNRMRRSGR