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CTGNICRSPIAERLAAAHGTLVGLPGFQASSAGTRAVIGHPIHQEAADVLENMGGVASDFAARQLTRRIV FDADLVLAMTKAHRDKVLELAPHKLSSTFALAEAAALASMGDNNRNIADLAALRPHVAAHDWSDVPDPIG QSRAVFEAVGSQIAELLTPVLDFCQRACADSPY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4757 | - | - | 100% (174) | protein tyrosine phosphatase |
| M. gilvum PYR-GCK | Mflv_2888 | - | 2e-05 | 37.21% (86) | protein tyrosine phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2258 | ptpA | 1e-06 | 29.07% (172) | phosphotyrosine protein phosphatase PTPA |
| M. tuberculosis H37Rv | Rv2234 | ptpA | 1e-06 | 29.07% (172) | phosphotyrosine protein phosphatase PTPA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1900c | - | 2e-07 | 30.61% (147) | putative low molecular weight protein tyrosine phosphatase |
| M. marinum M | MMAR_3309 | ptpA | 1e-06 | 36.56% (93) | phosphotyrosine protein phosphatase PtpA |
| M. avium 104 | MAV_2206 | - | 2e-06 | 29.31% (174) | low molecular weight protein-tyrosine-phosphatase |
| M. smegmatis MC2 155 | MSMEG_4309 | - | 4e-07 | 31.40% (172) | low molecular weight protein-tyrosine-phosphatase |
| M. thermoresistible (build 8) | TH_1463 | ptpA | 3e-06 | 37.11% (97) | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA |
| M. ulcerans Agy99 | MUL_1319 | ptpA | 2e-06 | 36.56% (93) | phosphotyrosine protein phosphatase PtpA |
| M. vanbaalenii PYR-1 | Mvan_1702 | - | 8e-36 | 53.47% (144) | protein tyrosine phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4309|M.smegmatis_MC2_155 --------------MSELHVTFVCSGNICRSPMAEKMFAHQIAERGLRDV
TH_1463|M.thermoresistible__bu -------------VSDLLHVTFVCSGNICRSPMAEKMFAHQIAQRGLADA
Mb2258|M.bovis_AF2122/97 ------------MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDA
Rv2234|M.tuberculosis_H37Rv ------------MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDA
MAV_2206|M.avium_104 ------------MSEP-LHVTFVCTGNICRSVMAEKMFADQLRRRGMADA
MMAR_3309|M.marinum_M ------------MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEA
MUL_1319|M.ulcerans_Agy99 ------------MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEA
MAB_1900c|M.abscessus_ATCC_199 --------------MSELHVTFVCTGNICRSPIAEKMLAHQLAERGLADR
Mflv_4757|M.gilvum_PYR-GCK MCTGNICRSPIAERLAAAHGTLVGLPGFQASSAGTRAVIGHPIHQEAADV
Mvan_1702|M.vanbaalenii_PYR-1 ----------MADQLR--------IPDFEASSAGTRALVGYPIHEYAALV
.: * . : . ..
MSMEG_4309|M.smegmatis_MC2_155 VRVTSAGTGSWHAGDGADERACLVLADRGYPTAHRAAVVDDDHLSADLVV
TH_1463|M.thermoresistible__bu MRVTSAGTGGWHVGAPADERARRTLRANGYPTDHRAAQLDDDHLSADLVV
Mb2258|M.bovis_AF2122/97 VRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLV
Rv2234|M.tuberculosis_H37Rv VRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLV
MAV_2206|M.avium_104 VRVSSAGTGNWHVGECADERAAGVLRAHGYPTEHRAAQVGAEHLSADLVV
MMAR_3309|M.marinum_M VRVTSAGTGNWHVGNRADERARQVLHSHGYPTDHCAAQVGTDHLEADLVI
MUL_1319|M.ulcerans_Agy99 VRVTSAGTGNWHVGNRADERARQVLYSHGYPTDHCAAQVGTDHLEADLVI
MAB_1900c|M.abscessus_ATCC_199 VRVTSAGTGDWHAGQPADERASSVLAEYGYPTAHRAAQVDEDHLSADLII
Mflv_4757|M.gilvum_PYR-GCK LENMGGVASDFAARQLTRRIVFDADLVLAMTKAHRDKVL--ELAPHKLSS
Mvan_1702|M.vanbaalenii_PYR-1 LEGLGGDVSGFVSRQLTPRIASSADLVLAMTREHRDAVL--ERAPKQLHR
:. .. ...: : . . . . . * : : .*
MSMEG_4309|M.smegmatis_MC2_155 AMGRNHARILADLGVEPDRLRMLRSFDPR-AGAHTPDVEDPYYGTRDDFE
TH_1463|M.thermoresistible__bu PMGRNHQRILVDLGVPHDRLRMLRSFDPR-SGAHALDVEDPYYGTQSDFD
Mb2258|M.bovis_AF2122/97 ALDRNHARLLRQLGVEAARVRMLRSFDPR-SGTHALDVEDPYYGDHSDFE
Rv2234|M.tuberculosis_H37Rv ALDRNHARLLRQLGVEAARVRMLRSFDPR-SGTHALDVEDPYYGDHSDFE
MAV_2206|M.avium_104 ALDRNHARMLRHLGVDEDRIRMLRSFDPR-TGAHTPDVDDPYYGDSKDFE
MMAR_3309|M.marinum_M ALGRNHARQLRQLGVEESRLRMLRSFDPR-SGAYVLDVEDPYYGGHDDFE
MUL_1319|M.ulcerans_Agy99 ALGRNHARQLRQLGVEESRLRMLRSFDPR-SGAYVLDVEDPYYGGHDDFE
MAB_1900c|M.abscessus_ATCC_199 ALARNHSRMLLHLGADPERVRLLRSFDPR-ASRAAMDVEDPYYGNRKDFV
Mflv_4757|M.gilvum_PYR-GCK TFALAEAAALASMGDNNRNIADLAALRPHVAAHDWSDVPDPIGQSRAVFE
Mvan_1702|M.vanbaalenii_PYR-1 TFTVVEAARLASEFEA-RDVAALAELRSRLTASESIDILDPMGREAEVFA
.: . * : * : .: :. *: ** *
MSMEG_4309|M.smegmatis_MC2_155 AVFEVIEAALPGLHDWVDEALAARGIVA
TH_1463|M.thermoresistible__bu EVFRVIDASLPGLHEWVDEQLDARGLAS
Mb2258|M.bovis_AF2122/97 EVFAVIESALPGLHDWVDERLARNGPS-
Rv2234|M.tuberculosis_H37Rv EVFAVIESALPGLHDWVDERLARNGPS-
MAV_2206|M.avium_104 RVYTVIEAALPGLHDWVDERLAQNGSS-
MMAR_3309|M.marinum_M EVLVVIEAALPGLHDWVDEQLAQDGKV-
MUL_1319|M.ulcerans_Agy99 EVLVVIEAALPGLHDWVDEQLAQDGKV-
MAB_1900c|M.abscessus_ATCC_199 EVLAVIEAALPGVHEWVDKTLAERENS-
Mflv_4757|M.gilvum_PYR-GCK AVGSQIAELLTPVLDFCQRACADSPY--
Mvan_1702|M.vanbaalenii_PYR-1 EVGEQIAGLLPPIMELCRRSARLAE---
* * *. : : .