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M. ulcerans Agy99 MUL_1319 (ptpA)

annotation: phosphotyrosine protein phosphatase PtpA
coordinates: 1416512 - 1417006
length: 164

SDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWHVGNRADERARQVLYSHGYPTD
HCAAQVGTDHLEADLVIALGRNHARQLRQLGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLV
VIEAALPGLHDWVDEQLAQDGKV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1319ptpA-100% (164)phosphotyrosine protein phosphatase PtpA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2258ptpA4e-7380.25% (162) phosphotyrosine protein phosphatase PTPA
M. gilvum PYR-GCKMflv_2888-6e-6372.08% (154) protein tyrosine phosphatase
M. tuberculosis H37RvRv2234ptpA4e-7380.25% (162) phosphotyrosine protein phosphatase PTPA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1900c-7e-6168.79% (157) putative low molecular weight protein tyrosine phosphatase
M. marinum MMMAR_3309ptpA5e-9499.39% (164) phosphotyrosine protein phosphatase PtpA
M. avium 104MAV_2206-1e-6775.80% (157) low molecular weight protein-tyrosine-phosphatase
M. smegmatis MC2 155MSMEG_4309-2e-6473.91% (161) low molecular weight protein-tyrosine-phosphatase
M. thermoresistible (build 8)TH_1463ptpA3e-6471.60% (162) PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA
M. vanbaalenii PYR-1Mvan_3622-1e-6571.70% (159) protein tyrosine phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1900c|M.abscessus_ATCC_199      MSEL--HVTFVCTGNICRSPIAEKMLAHQLAERGLADRVRVTSAGTGDWH
MSMEG_4309|M.smegmatis_MC2_155      MSEL--HVTFVCSGNICRSPMAEKMFAHQIAERGLRDVVRVTSAGTGSWH
MUL_1319|M.ulcerans_Agy99           MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
MMAR_3309|M.marinum_M               MSDSTLHVTFVCTGNICRSPMAEKMFAHQLRERGLGEAVRVTSAGTGNWH
Mb2258|M.bovis_AF2122/97            MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
Rv2234|M.tuberculosis_H37Rv         MSDP-LHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWH
MAV_2206|M.avium_104                MSEP-LHVTFVCTGNICRSVMAEKMFADQLRRRGMADAVRVSSAGTGNWH
Mflv_2888|M.gilvum_PYR-GCK          MSEE-LHVTFVCSGNICRSPMAEKMFAHQIDGRGLAGVVRVTSAGTGHWH
Mvan_3622|M.vanbaalenii_PYR-1       MSEL-LHVTFICSGNICRSPMAEKMFAHQIGERGLAHVVRVTSAGTGHWH
TH_1463|M.thermoresistible__bu      VSDL-LHVTFVCSGNICRSPMAEKMFAHQIAQRGLADAMRVTSAGTGGWH
                                    :*:   ****:*:****** :****:*.*:  **:   :**:***** **

MAB_1900c|M.abscessus_ATCC_199      AGQPADERASSVLAEYGYPTAHRAAQVDEDHLSADLIIALARNHSRMLLH
MSMEG_4309|M.smegmatis_MC2_155      AGDGADERACLVLADRGYPTAHRAAVVDDDHLSADLVVAMGRNHARILAD
MUL_1319|M.ulcerans_Agy99           VGNRADERARQVLYSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
MMAR_3309|M.marinum_M               VGNRADERARQVLHSHGYPTDHCAAQVGTDHLEADLVIALGRNHARQLRQ
Mb2258|M.bovis_AF2122/97            VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
Rv2234|M.tuberculosis_H37Rv         VGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQ
MAV_2206|M.avium_104                VGECADERAAGVLRAHGYPTEHRAAQVGAEHLSADLVVALDRNHARMLRH
Mflv_2888|M.gilvum_PYR-GCK          EGEPADRRASHTLREHGYPTTHRAAQITDEHLAADLVVALGRNHLRMLQH
Mvan_3622|M.vanbaalenii_PYR-1       EGEPADRRAGHVLRAHGYPSSHRATQINDDHLAADLVVALGRNHQRMLQH
TH_1463|M.thermoresistible__bu      VGAPADERARRTLRANGYPTDHRAAQLDDDHLSADLVVPMGRNHQRILVD
                                     *  **.**  .*   ***: * *: :  :** ***::.: *** * * .

MAB_1900c|M.abscessus_ATCC_199      LGADPERVRLLRSFDPRASRAAMDVEDPYYGNRKDFVEVLAVIEAALPGV
MSMEG_4309|M.smegmatis_MC2_155      LGVEPDRLRMLRSFDPRAGAHTPDVEDPYYGTRDDFEAVFEVIEAALPGL
MUL_1319|M.ulcerans_Agy99           LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
MMAR_3309|M.marinum_M               LGVEESRLRMLRSFDPRSGAYVLDVEDPYYGGHDDFEEVLVVIEAALPGL
Mb2258|M.bovis_AF2122/97            LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
Rv2234|M.tuberculosis_H37Rv         LGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGL
MAV_2206|M.avium_104                LGVDEDRIRMLRSFDPRTGAHTPDVDDPYYGDSKDFERVYTVIEAALPGL
Mflv_2888|M.gilvum_PYR-GCK          MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTQDDFEETFAVIDASLPGL
Mvan_3622|M.vanbaalenii_PYR-1       MGVPAERLRMLRSFDPRSGAHVLDVEDPYYGTHDDFEDVFTVIDAALPGL
TH_1463|M.thermoresistible__bu      LGVPHDRLRMLRSFDPRSGAHALDVEDPYYGTQSDFDEVFRVIDASLPGL
                                    :*.   *:*:*******:.  . **:*****  .**  .  **:::***:

MAB_1900c|M.abscessus_ATCC_199      HEWVDKTLAERENS-
MSMEG_4309|M.smegmatis_MC2_155      HDWVDEALAARGIVA
MUL_1319|M.ulcerans_Agy99           HDWVDEQLAQDGKV-
MMAR_3309|M.marinum_M               HDWVDEQLAQDGKV-
Mb2258|M.bovis_AF2122/97            HDWVDERLARNGPS-
Rv2234|M.tuberculosis_H37Rv         HDWVDERLARNGPS-
MAV_2206|M.avium_104                HDWVDERLAQNGSS-
Mflv_2888|M.gilvum_PYR-GCK          HSWVDERLAGREQAG
Mvan_3622|M.vanbaalenii_PYR-1       HGWVDERLADREQVG
TH_1463|M.thermoresistible__bu      HEWVDEQLDARGLAS
                                    * ***: *